LOCUS       NM_028260                926 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus IMP1 inner mitochondrial membrane peptidase-like (S.
            cerevisiae) (Immp1l), mRNA; nuclear gene for mitochondrial product.
ACCESSION   NM_028260
VERSION     NM_028260.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 926)
  AUTHORS   Favor,J., Bradley,A., Conte,N., Janik,D., Pretsch,W., Reitmeir,P.,
            Rosemann,M., Schmahl,W., Wienberg,J. and Zaus,I.
  TITLE     Analysis of Pax6 contiguous gene deletions in the mouse, Mus
            musculus, identifies regions distinct from Pax6 responsible for
            extreme small-eye and belly-spotting phenotypes
  JOURNAL   Genetics 182 (4), 1077-1088 (2009)
   PUBMED   19474196
REFERENCE   2  (bases 1 to 926)
  AUTHORS   Bailey,P.J., Klos,J.M., Andersson,E., Karlen,M., Kallstrom,M.,
            Ponjavic,J., Muhr,J., Lenhard,B., Sandelin,A. and Ericson,J.
  TITLE     A global genomic transcriptional code associated with CNS-expressed
            genes
  JOURNAL   Exp Cell Res 312 (16), 3108-3119 (2006)
   PUBMED   16919269
REFERENCE   3  (bases 1 to 926)
  AUTHORS   Luo,W., Fang,H. and Green,N.
  TITLE     Substrate specificity of inner membrane peptidase in yeast
            mitochondria
  JOURNAL   Mol Genet Genomics 275 (5), 431-436 (2006)
   PUBMED   16450175
  REMARK    GeneRIF: Murine precursors to cytochrome c1 and
            glycerol-3-phosphate dehydrogenase are cleaved by murine Imp2.
REFERENCE   4  (bases 1 to 926)
  AUTHORS   Burri,L., Strahm,Y., Hawkins,C.J., Gentle,I.E., Puryer,M.A.,
            Verhagen,A., Callus,B., Vaux,D. and Lithgow,T.
  TITLE     Mature DIABLO/Smac is produced by the IMP protease complex on the
            mitochondrial inner membrane
  JOURNAL   Mol Biol Cell 16 (6), 2926-2933 (2005)
   PUBMED   15814844
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL590380.9.
            
            On Jan 12, 2022 this sequence version replaced NM_028260.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK015978.1, AK011466.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on single
                                                  protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-63                AL590380.9         127664-127726
            64-169              AL590380.9         131320-131425
            170-303             AL590380.9         153715-153848
            304-392             AL590380.9         156261-156349
            393-519             AL590380.9         159988-160114
            520-630             AL590380.9         187176-187286
            631-926             AL590380.9         188260-188555
FEATURES             Location/Qualifiers
     source          1..926
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 55.43 cM"
     gene            1..926
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
                     /note="IMP1 inner mitochondrial membrane peptidase-like
                     (S. cerevisiae)"
                     /db_xref="GeneID:66541"
                     /db_xref="MGI:MGI:1913791"
     exon            1..63
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            64..169
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            170..303
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             199..699
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
                     /note="IMP1-like protein"
                     /codon_start=1
                     /product="mitochondrial inner membrane protease subunit 1"
                     /protein_id="NP_082536.1"
                     /db_xref="CCDS:CCDS38192.1"
                     /db_xref="GeneID:66541"
                     /db_xref="MGI:MGI:1913791"
                     /translation="MLRGVLGKAFRLAGYTIQYGCIAHCAFEYVGGVVMCSGPSMEPT
                     IQNSDIVFAENLSRHFYGIQRGDIVIAKSPSDPKSNICKRVIGLEGDKILSTSPSDVF
                     KSRSYVPTGHVWLEGDNLQNSTDSRYYGPIPYGLIRGRIFFKIWPFSDFGFLRDSPNG
                     QRFSDD"
     exon            304..392
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            393..519
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            520..630
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            631..926
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      766..771
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
                     /note="hexamer: AATAAA"
     polyA_site      791
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
                     /note="major polyA site"
     regulatory      841..846
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
                     /note="hexamer: AGTAAA"
     regulatory      855..860
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
                     /note="hexamer: GATAAA"
     polyA_site      866
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
     polyA_site      873
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
     regulatory      905..910
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
                     /note="hexamer: AATATA"
     polyA_site      926
                     /gene="Immp1l"
                     /gene_synonym="1500034J20Rik; 2610528O17Rik"
ORIGIN      
        1 gtacgcggcc ctggtccgtc tgagtcctgg ccgaggaact tctgttggtg tttggggccg
       61 caggaatcgg aagccatgga tgacccatgc acgctttgag acctccgtca gatctggggt
      121 ttcctggaaa cctaccataa agttgaacaa attgtagaac agacttatgg ctggtggtag
      181 cagagtcaac atcaaagtat gcttcgtggt gttctgggaa aggcttttcg acttgctggc
      241 tataccattc agtatggctg catagctcat tgtgcttttg aatacgttgg tggtgttgta
      301 atgtgttctg gaccatcaat ggaacccaca attcaaaatt cagatattgt ctttgcagaa
      361 aatcttagcc gacattttta tggcatccaa agaggtgaca ttgtaattgc aaaaagccca
      421 agtgatccaa aatcaaatat ctgtaaaaga gtaattggtt tggaaggaga caaaatcctc
      481 agcactagtc catctgatgt atttaagagc cgcagttacg tgccaacagg tcatgtttgg
      541 ttagaaggtg ataacttaca gaattctacc gattccaggt attatggacc tataccatat
      601 ggactaataa gaggacgtat cttctttaag atttggcctt tcagtgactt cggatttctg
      661 cgtgacagcc caaatggcca gagattttct gatgattaat aagtatttct tgattactgt
      721 ctcctattca agtgaattta ttactacagt tgaaaccatg aacttaataa actatttgct
      781 attcagtttt atttatgttt taaatataag agtaaatatc acactctgca atatatatta
      841 agtaaaagta tttagataaa aattgaccca aaacaaattt tctttctaaa ttgtatgata
      901 taaaaatata ttggggaaga aatcca
//
