LOCUS       NM_153511               1647 bp    mRNA    linear   ROD 04-DEC-2024
DEFINITION  Mus musculus interleukin 36G (Il36g), mRNA.
ACCESSION   NM_153511
VERSION     NM_153511.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1647)
  AUTHORS   Wang,L., Tu,Y., Wu,W., Tu,Y., Yang,Z., Chai,Y., Yang,X. and He,L.
  TITLE     Role of interleukin-36gamma induced by ultraviolet radiation in
            chronic actinic dermatitis
  JOURNAL   Photodermatol Photoimmunol Photomed 39 (6), 598-606 (2023)
   PUBMED   37545106
  REMARK    GeneRIF: Role of interleukin-36gamma induced by ultraviolet
            radiation in chronic actinic dermatitis.
REFERENCE   2  (bases 1 to 1647)
  AUTHORS   Cho,W.J., Elbasiony,E., Singh,A., Mittal,S.K. and Chauhan,S.K.
  TITLE     IL-36gamma Augments Ocular Angiogenesis by Promoting the Vascular
            Endothelial Growth Factor-Vascular Endothelial Growth Factor
            Receptor Axis
  JOURNAL   Am J Pathol 193 (11), 1740-1749 (2023)
   PUBMED   36740182
  REMARK    GeneRIF: IL-36gamma Augments Ocular Angiogenesis by Promoting the
            Vascular Endothelial Growth Factor-Vascular Endothelial Growth
            Factor Receptor Axis.
REFERENCE   3  (bases 1 to 1647)
  AUTHORS   Anzaghe,M., Niles,M.A., Korotkova,E., Dominguez,M., Kronhart,S.,
            Ortega Iannazzo,S., Bechmann,I., Bachmann,M., Muhl,H., Kochs,G. and
            Waibler,Z.
  TITLE     Interleukin-36gamma is causative for liver damage upon infection
            with Rift Valley fever virus in type I interferon
            receptor-deficient mice
  JOURNAL   Front Immunol 14, 1194733 (2023)
   PUBMED   37720217
  REMARK    GeneRIF: Interleukin-36gamma is causative for liver damage upon
            infection with Rift Valley fever virus in type I interferon
            receptor-deficient mice.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1647)
  AUTHORS   Manzanares-Meza,L.D., Gutierrez-Roman,C.I., Jimenez-Pineda,A.,
            Castro-Martinez,F., Patino-Lopez,G., Rodriguez-Arellano,E.,
            Valle-Rios,R., Ortiz-Navarrete,V.F. and Medina-Contreras,O.
  TITLE     IL-36gamma is secreted through an unconventional pathway using the
            Gasdermin D and P2X7R membrane pores
  JOURNAL   Front Immunol 13, 979749 (2022)
   PUBMED   36059446
  REMARK    GeneRIF: IL-36gamma is secreted through an unconventional pathway
            using the Gasdermin D and P2X7R membrane pores.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1647)
  AUTHORS   Shukla,S., Cho,W.K., Elbasiony,E., Singh,R.B., Mittal,S.K. and
            Chauhan,S.K.
  TITLE     Non-immune and immune functions of interleukin-36gamma suppress
            epithelial repair at the ocular surface
  JOURNAL   FASEB J 36 (8) (2022)
   PUBMED   35781326
  REMARK    GeneRIF: Non-immune and immune functions of interleukin-36gamma
            suppress epithelial repair at the ocular surface.
REFERENCE   6  (bases 1 to 1647)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   7  (bases 1 to 1647)
  AUTHORS   Egawa,G., Osawa,M., Uemura,A., Miyachi,Y. and Nishikawa,S.
  TITLE     Transient expression of ephrin b2 in perinatal skin is required for
            maintenance of keratinocyte homeostasis
  JOURNAL   J Invest Dermatol 129 (10), 2386-2395 (2009)
   PUBMED   19571816
REFERENCE   8  (bases 1 to 1647)
  AUTHORS   Rogers,M.S., Rohan,R.M., Birsner,A.E. and D'Amato,R.J.
  TITLE     Genetic loci that control vascular endothelial growth
            factor-induced angiogenesis
  JOURNAL   FASEB J 17 (14), 2112-2114 (2003)
   PUBMED   12958152
REFERENCE   9  (bases 1 to 1647)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   10 (bases 1 to 1647)
  AUTHORS   Taylor,S.L., Renshaw,B.R., Garka,K.E., Smith,D.E. and Sims,J.E.
  TITLE     Genomic organization of the interleukin-1 locus
  JOURNAL   Genomics 79 (5), 726-733 (2002)
   PUBMED   11991723
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY778759.1 and AK081783.1.
            
            On Mar 14, 2009 this sequence version replaced NM_153511.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK081783.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849376, SAMN00849387
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-6                 BY778759.1         2-7
            7-1647              AK081783.1         2-1642
FEATURES             Location/Qualifiers
     source          1..1647
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 16.24 cM"
     gene            1..1647
                     /gene="Il36g"
                     /gene_synonym="If36g; IL-36gamma; Il1f9"
                     /note="interleukin 36G"
                     /db_xref="GeneID:215257"
                     /db_xref="MGI:MGI:2449929"
     exon            1..275
                     /gene="Il36g"
                     /gene_synonym="If36g; IL-36gamma; Il1f9"
                     /inference="alignment:Splign:2.1.0"
     exon            276..418
                     /gene="Il36g"
                     /gene_synonym="If36g; IL-36gamma; Il1f9"
                     /inference="alignment:Splign:2.1.0"
     CDS             295..876
                     /gene="Il36g"
                     /gene_synonym="If36g; IL-36gamma; Il1f9"
                     /note="IL-1F9; interleukin 1 family, member 9"
                     /codon_start=1
                     /product="interleukin-36 gamma"
                     /protein_id="NP_705731.2"
                     /db_xref="CCDS:CCDS50518.1"
                     /db_xref="GeneID:215257"
                     /db_xref="MGI:MGI:2449929"
                     /translation="MENNEKKNIVYGSDVEMEHERAGLFVSSAMFSKHPFSTHISGRE
                     TPDFGEVFDLDQQVWIFRNQALVTVPRSHRVTPVSVTILPCKYPESLEQDKGIAIYLG
                     IQNPDKCLFCKEVNGHPTLLLKEEKILDLYHHPEPMKPFLFYHTRTGGTSTFESVAFP
                     GHYIASSKTGNPIFLTSKKGEYYNINFNLDIKS"
     exon            419..526
                     /gene="Il36g"
                     /gene_synonym="If36g; IL-36gamma; Il1f9"
                     /inference="alignment:Splign:2.1.0"
     exon            527..666
                     /gene="Il36g"
                     /gene_synonym="If36g; IL-36gamma; Il1f9"
                     /inference="alignment:Splign:2.1.0"
     exon            667..1647
                     /gene="Il36g"
                     /gene_synonym="If36g; IL-36gamma; Il1f9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atcattacac ctgggagctg cccaagctgg gatttggtct tctagacttt ccataaggac
       61 tctttcttgc catgtaccta caaacctaca aaaccctttg agtgcgcctc tgagtgtgga
      121 gctttctgca gttcagggtt cagtgaatgg acagatctgt cttgctgtaa gtgatcctgt
      181 gagcgatcct gtgagcgatc ctgtgagcga tcctgtgagc gatcctgtga gcgatcctgt
      241 gagtgatcct gtgagcaatc ctgtgagagc tctgtgcacc agaacaagat cacgatggaa
      301 aacaatgaaa aaaaaaacat tgtgtatgga agtgatgttg agatggaaca cgagagagct
      361 gggctatttg tatcttcagc tatgttttct aaacacccat tttctacaca catctcagga
      421 agagaaactc ctgactttgg ggaggttttt gacttggacc agcaggtgtg gatctttcgt
      481 aatcaggccc ttgtgacagt tccacgaagc cacagagtaa ccccagtcag cgtgactatc
      541 ctcccatgca agtacccaga gtctcttgaa caggacaaag ggattgccat ttatttggga
      601 attcagaatc cagataaatg cctgttttgt aaggaagtta atggacaccc tactttgctg
      661 ctaaaggaag agaagatttt ggatttgtac caccaccctg agccaatgaa gccattcctg
      721 ttttaccaca cccggacagg tggaacatcc acctttgaat cagtggcttt ccctggccac
      781 tatattgcct cctccaagac tggcaacccc atcttcctca catcaaaaaa gggagaatat
      841 tacaacatta acttcaattt agatataaag tcttaaactc agcatggaag tggagggttg
      901 gttagaactc ttcctcttaa aacatcaaac ctctaatatg ttatcatttg tttgatctat
      961 ggtattttca tactgaaagg taagcaggac caacattatc tcctttcata gatgaagaag
     1021 caacaaaata atgcatactc caaagtcggt gggattggag tggtgtaagg atgttctcta
     1081 agactgaagt ggtccaatct ataagacatc atgtctgaga aatagggtgc tgtgccacag
     1141 tgtataaaac ctagaatgcc ctgtgtgtga gtggtgacat cctcatttcc agccattggc
     1201 ctgattcata ccatgttttc acacatttgt aatatcaact ccttgcattt ggatagcaga
     1261 ggcctcacaa tgacatttgc ctcaacagct aatagctttg atctttcaat gctgtgtaga
     1321 tctgaataca ctagaaaagg aattagaatc ctgagtgaat gaactgtgag gagccgccct
     1381 cacatttgcc attataagat ggcactgaca gctgtgttct aagtggtaaa catagtctgc
     1441 acacatgcag gggcagtttt cccaccatgt gttctgcctt tcccgtgatg acaactgggc
     1501 cgatgggctg cagccaatca gggagtaata cgtcctaggt ggaggataat tctccttaaa
     1561 agggacgggg ttctggcact ctctcccttc cttgcttgct ctcttgcact ctggctcctg
     1621 aagatgtaag caataaagct ttgccgc
//
