LOCUS       NM_030688               5422 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus interleukin 1 receptor accessory protein-like 2
            (Il1rapl2), mRNA.
ACCESSION   NM_030688
VERSION     NM_030688.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5422)
  AUTHORS   Ferrante,M.I., Ghiani,M., Bulfone,A. and Franco,B.
  TITLE     IL1RAPL2 maps to Xq22 and is specifically expressed in the central
            nervous system
  JOURNAL   Gene 275 (2), 217-221 (2001)
   PUBMED   11587848
REFERENCE   2  (bases 1 to 5422)
  AUTHORS   Born,T.L., Smith,D.E., Garka,K.E., Renshaw,B.R., Bertles,J.S. and
            Sims,J.E.
  TITLE     Identification and characterization of two members of a novel class
            of the interleukin-1 receptor (IL-1R) family. Delineation of a new
            class of IL-1R-related proteins based on signaling
  JOURNAL   J Biol Chem 275 (39), 29946-29954 (2000)
   PUBMED   10882729
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK045976.1 and AL672067.5.
            
            On Aug 27, 2015 this sequence version replaced NM_030688.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK045976.1, AF284437.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164131, SAMN01164132
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2446              AK045976.1         2-2447
            2447-5422           AL672067.5         221707-224682
FEATURES             Location/Qualifiers
     source          1..5422
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 59.1 cM"
     gene            1..5422
                     /gene="Il1rapl2"
                     /note="interleukin 1 receptor accessory protein-like 2"
                     /db_xref="GeneID:60367"
                     /db_xref="MGI:MGI:1913106"
     exon            1..889
                     /gene="Il1rapl2"
                     /inference="alignment:Splign:2.1.0"
     exon            890..990
                     /gene="Il1rapl2"
                     /inference="alignment:Splign:2.1.0"
     CDS             909..2969
                     /gene="Il1rapl2"
                     /EC_number="3.2.2.6"
                     /note="X-linked interleukin-1 receptor accessory
                     protein-like 2; TIGIRR-1; IL1RAPL-2; IL-1RAPL-2;
                     IL-1-RAPL-2; IL1RAPL-2-related protein; IL-1 receptor
                     accessory protein-like 2; three immunoglobulin
                     domain-containing IL-1 receptor-related 1"
                     /codon_start=1
                     /product="X-linked interleukin-1 receptor accessory
                     protein-like 2 precursor"
                     /protein_id="NP_109613.1"
                     /db_xref="CCDS:CCDS30429.1"
                     /db_xref="GeneID:60367"
                     /db_xref="MGI:MGI:1913106"
                     /translation="MKLPLLLALVVCSAVSTNLKMVSKRNSVDGCIDWSVDLKTYMAL
                     AGEPVRVKCALFYSYIRTNYSMAQSTGLRLMWYRNKGDLEEPIIFSEVRMSKEEDAIW
                     FHSAEEQDSGFYTCVLRNSTYCMKVSMSLTVAENESGLCYNSRIRYLEKSEVTKRKEI
                     SCPDMDDFKKSDQEPDVVWYKECKPKMWRSIIIQKGNALLIQEVQEEDGGNYTCELKY
                     EGKLVRRTTELKVTALLTDKPPKPLFPMENQPSVIDVQLGKPLNIPCKAFFGFSGESG
                     PMIYWMKGEKFIEELAGHIREGEIRLLKEHLGEKEVELTLIFDSVVEADLANYTCHVE
                     NRNGRKHASVLLRKKDLIYKIELAGGLGAIFLLLILLLVVYKCYNIELMLFYRQRFGG
                     DETTDDNKEYDAYLSYTKVDQDTLDCDNTEEEQFALEILPDVLEKHYGYKLFIPERDL
                     IPSGTYIEDLTRCVEQSRRLIIVLTPDYILRRGWSIFELESRLHNMLVSGEIKVILIE
                     CTELKGKVNCQEVESLKHNIKLLSLIKWKGPKSSKLNSKFWKHLVYEMPIKKKEMLSH
                     CHVLDSAEQGLFGELQPIPSIAMTSTSATMVPSQADLPEFHHSDSMQMRHCCRGYQHE
                     MPANTLSVPSLGNHHTYCNLPLTLLNGQLPLNNSLKETEEFSRNNPLLPLTSKELSFT
                     SDIW"
     exon            991..1264
                     /gene="Il1rapl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1265..1451
                     /gene="Il1rapl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1605
                     /gene="Il1rapl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1606..1680
                     /gene="Il1rapl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1681..1810
                     /gene="Il1rapl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1811..1956
                     /gene="Il1rapl2"
                     /inference="alignment:Splign:2.1.0"
     exon            1957..2100
                     /gene="Il1rapl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2101..2271
                     /gene="Il1rapl2"
                     /inference="alignment:Splign:2.1.0"
     exon            2272..5422
                     /gene="Il1rapl2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5245..5250
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Il1rapl2"
                     /note="hexamer: ATTAAA"
     polyA_site      5267
                     /gene="Il1rapl2"
                     /note="major polyA site"
ORIGIN      
        1 tctctaattc gcacctcccg gttgcagtca gtcagccagg aggcaccaaa ctgttagcaa
       61 ggaagccaag gctctgggtg acttccacta ccctcccact tccctactcc aggcatattt
      121 tggagaggct ggcgacagtg gcaggatgtg agaggagcgc agcgcttgcc cctcgcactc
      181 ctctctttga gggctggggt gcgagtggct tctgcgcact ggctggaggg ctccgggaag
      241 cgctggagcc acgcaggagg gaggcgggcg agctgggtgg gtgcaagcta ggctgcctgc
      301 accacagccc ggctgagccg gtggctccgc tgctttctgg agctcgcgag tcccgtgagc
      361 ggtggtagca ccgccaactg gggtgccccg cgtcccgcgt cccagcgtgg cgcgcactgt
      421 tcggcctgaa ccaggtgcgg ctggaaggag gcagcaccaa agctaactcg ctccaaagaa
      481 tcttggaggc gggcaccttt gagaatccat tcactcagct gagaagtggt acctgccatt
      541 ctaactatag ggtctaatga tttggaaacc tcctgtaacc tgtcccctct ccagtacatc
      601 ccgaagtcca cagaagcggc actgaactcc aggaatcttc cgaacttccc aggtatcctc
      661 gctggcttag gactggaagt gtagtgaacc tggtgggaga ctttgagtcc gcggcgtggg
      721 agacaccttc caaaagcccc ctccatccca ttcctctctg ggcagcttta ctggccgccc
      781 tggaagccaa accctgcgct cttctgaact ctgctcttca tcgcgccctg ggcatggaac
      841 tatacgcctg aaacctgctg gaccttgctg gttgttttgc aagactcagc tgccagagaa
      901 cttgaacaat gaagctgcca cttcttctgg ccctggtggt ctgttctgca gtcagtacaa
      961 atttgaagat ggtgtcaaaa agaaattctg tggatggctg cattgattgg tcggtggatc
     1021 tcaagacata catggctttg gcaggtgaac ctgtccgagt gaaatgtgcc cttttctaca
     1081 gttatatccg caccaactac agcatggccc agagtaccgg gctcaggctc atgtggtata
     1141 gaaacaaagg tgacttggaa gagcccatca tcttttcaga ggtcaggatg agtaaagagg
     1201 aagacgccat atggtttcac tcagctgagg aacaagacag tggattctac acttgtgttt
     1261 taagaaactc cacatattgc atgaaggtgt caatgtcctt gactgttgca gagaatgaat
     1321 caggcctgtg ctacaatagc aggatccgct acttagagaa atctgaagtt accaaaagaa
     1381 aggagatctc atgcccagac atggatgact ttaagaagtc tgatcaggaa cctgatgtcg
     1441 tatggtacaa ggaatgcaag ccaaaaatgt ggagaagcat aataatacag aagggaaatg
     1501 ctcttctcat ccaagaagtt caagaagaag atggaggaaa ttatacatgt gaacttaaat
     1561 atgaaggaaa acttgtaaga cgaacaacag aattgaaagt tacagcttta ctcacagaca
     1621 agcctcccaa gccattgttc cccatggaaa atcagccaag tgttatagat gtccagctgg
     1681 gtaaacctct gaacatccct tgcaaagctt tctttggatt cagtggggag tctggaccaa
     1741 tgatctactg gatgaaaggc gagaagttta ttgaagaact ggcaggtcac attagagaag
     1801 gtgaaataag gctcctcaaa gagcatcttg gagaaaaaga agttgagttg acacttatct
     1861 ttgactcagt ggtagaagct gacttggcta attatacctg ccatgtggag aacagaaatg
     1921 gacggaaaca cgccagtgtt ctactgcgaa aaaaggattt aatatacaaa attgagcttg
     1981 cagggggcct aggagcaatc ttcctactac ttatactgct actggtggtc tacaaatgct
     2041 acaacataga actgatgctt ttctacagac agcgttttgg aggtgatgaa actactgatg
     2101 acaacaagga atatgatgcg tatctctctt acacaaaagt ggatcaagat actttggact
     2161 gtgacaatac tgaggaagag cagtttgctc ttgaaatact gccagatgtc ttagaaaaac
     2221 actatggata taaactcttc atcccagaaa gggatctcat tccaagtgga acatatattg
     2281 aagatctcac aagatgtgtt gagcaaagca gacgacttat tatcgtgcta actccagact
     2341 atattctcag acggggatgg agtattttcg aactggaaag cagactccat aacatgctag
     2401 tcagtggaga aatcaaagtg attttgattg agtgtacaga attaaaaggg aaggtgaatt
     2461 gccaggaagt ggaatcacta aagcacaaca tcaaacttct gtcactgatc aagtggaagg
     2521 gacccaaaag cagcaaatta aattctaagt tttggaagca cttagtgtat gaaatgccca
     2581 tcaagaaaaa agaaatgcta tcccactgcc atgttctaga ctctgccgag caggggcttt
     2641 ttggagaact tcagcctata ccttcaattg ccatgacgag tacctcagcc acaatggtgc
     2701 catcgcaagc tgatctccct gagttccatc attcggattc aatgcaaatg aggcactgtt
     2761 gcagaggata ccaacacgag atgccagcca acaccctgtc agtaccctcc ttaggcaacc
     2821 accacactta ctgtaacttg ccactgacac tactcaatgg acagctaccc cttaacaact
     2881 ccttaaaaga gactgaggaa ttttcaagga acaatcccct actgccatta acatccaaag
     2941 agcttagctt caccagtgat atttggtagc ggaaaacaaa aaatctcaac tcctcagaac
     3001 agctatatga gaatatgaaa tttcggctac agtgagaata aattacacct aaaaacatta
     3061 aggtgctgaa aatgtgaaga aaaaggcaca acaatcatgt ttgtacttaa atatttatta
     3121 tttaaattta tagagtagta ggggaataaa aggtcttgct tttgtagtgt ggcaccttgt
     3181 cacaatgtac agatttgatt tttttctgga aaaaaattga attgtgtcct tttcaagtag
     3241 gttttatggc accatatgga ctgcccatac ttagcattta aacagtattt ttcataaaaa
     3301 aaaaaataag agaaagaaag acagacagac agacacacag aaggaaagaa agaaagaaag
     3361 aaagaaagaa agaaagaaag aaagaaagaa agaagaagga aagaggaagg aagaaagaaa
     3421 gaaagaaaga aagaaagaaa gaaagaaaga aggaaagaaa gagagagaga gagagaaaga
     3481 aagaaagaaa gaaagaaaga aagaaagaaa gaaagaaagg aaggaaggaa ggaaggaagg
     3541 aaggaagaaa gaaaacttga aattttcact gaatttaaag agtctgaatg aaggtttaag
     3601 ggaaaagaga acttctataa agtgactgaa agcgtctgag aattgtacag gaacaaaaca
     3661 gattgaggca gccaattgga agactatcca agaagatctg ttgagaaaat gattgaaaca
     3721 tttgcatctt cttcaatata atagacaact cttgtagact aaaccaacag cttgtaacaa
     3781 tagcttttaa ttctaataga caagcacatc aactgtactc aaactggtag gtaggtcaac
     3841 tatgcacatt tcttcatcaa atgaatagat agctctaaga tctttaaaaa tgatttttag
     3901 taaaacgtat gactttctgt atcattagaa aaaacatttt gcaactttaa aaaatacatc
     3961 ttaaagtgca caatttattg tttctgtaaa ctttcacatt tagatgtgga ttttccccca
     4021 aaacacactt accatcttct ctaagattta tgtgaagatg taggcattgc cctacttgtt
     4081 tttcagcctc attgcaagtt gagcttaaat atatattgac tgaaaatgtc tgcagttgaa
     4141 gagaagtaac gactattcag aaatgttgag ctaagtgatt tgagtttact agtggtagag
     4201 cagtgactgc agacttgctc atttgcagca tagttgtgaa atagacttct attctgtaca
     4261 ctatatgcac aaggctccag cagaagtatc tctattcctg gtgcttcaaa gaatatattt
     4321 agtagactga gcttgttcat cttcatacag agactgggac tgcactatat cagcacatca
     4381 ttgtgaataa cctttctcct gatggttgta tggaacgtat ccctcttcta ggattcattg
     4441 tggatcatga ctttttgtca cttaatttgg tgtcctctcc caccttatac ctggtggtgg
     4501 tggggatcaa ctgcttaact gcttctcaaa gttgattcag aaattgtacg aatggttctt
     4561 acagaaaatc cttgtacaat tatgaaaaaa gatgatatat acaatgtgta aaaattaaga
     4621 ctttgtttac cccttgtgat tgtgagaccc aaaattatta tcaaatagga gaaaatatgc
     4681 tttgacgaga tttgtctcta attgctttcc atggttgctt ccctgtgatc catcagtgct
     4741 gtgaaattac ttatttctct gttgcttttc tacatcttat ctgttcagaa aatccatttt
     4801 tggaccaaaa ccttggaagt ttcacagtga tatatgttta ttttacaggg agacatcagt
     4861 tgctcctttg aaaagtcctg ttcaccatat gtgggtattt catagatgtg tttttcccca
     4921 agaatagaaa cttcagaaaa aaaaaactat aggtatttca aaatgaaaat ctatcaattc
     4981 tgaagtgttt tccaagtgtt ataaagttgt atttattctg ggtgttcttt aatgctatgt
     5041 gtaatgacta aattaataat ctgcatgaaa tgagtggtac atgttttaag tggacaattg
     5101 tactttttcc tattttattt ttcacagaaa tctagatgaa ttcaaataga atgttcagtc
     5161 atatttttaa actaatagtt ctgtattgag catgccagtt ctgaaaatat aacgtgggcc
     5221 tctttacttc ctttatttac aatgattaaa cgtgggtagc aatttgagtt ggctggccac
     5281 aatgtgtccc ttcactgctt gtaggtactc agaaacacag cattcacact tgtcctgggg
     5341 aacttgacaa gaaacctttt ctaccatttt caggaaataa tgtgtacact atctataaaa
     5401 atttatttct agatggcaat tc
//
