LOCUS       NM_001418762            3964 bp    mRNA    linear   ROD 14-FEB-2025
DEFINITION  Mus musculus IKAROS family zinc finger 5 (Ikzf5), transcript
            variant 3, mRNA.
ACCESSION   NM_001418762
VERSION     NM_001418762.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3964)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3964)
  AUTHORS   Nakata,H., Hashimoto,T. and Yoshiki,A.
  TITLE     Quick validation of genetic quality for conditional alleles in mice
  JOURNAL   Genes Cells 26 (4), 240-245 (2021)
   PUBMED   33540482
REFERENCE   3  (bases 1 to 3964)
  AUTHORS   Kasowitz,S.D., Ma,J., Anderson,S.J., Leu,N.A., Xu,Y., Gregory,B.D.,
            Schultz,R.M. and Wang,P.J.
  TITLE     Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and
            splicing during mouse oocyte development
  JOURNAL   PLoS Genet 14 (5), e1007412 (2018)
   PUBMED   29799838
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3964)
  AUTHORS   Martin-Ibanez,R., Pardo,M., Giralt,A., Miguez,A., Guardia,I.,
            Marion-Poll,L., Herranz,C., Esgleas,M., Garcia-Diaz Barriga,G.,
            Edel,M.J., Vicario-Abejon,C., Alberch,J., Girault,J.A., Chan,S.,
            Kastner,P. and Canals,J.M.
  TITLE     Helios expression coordinates the development of a subset of
            striatopallidal medium spiny neurons
  JOURNAL   Development 144 (8), 1566-1577 (2017)
   PUBMED   28289129
REFERENCE   5  (bases 1 to 3964)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643.. PMID: 29144450]
REFERENCE   6  (bases 1 to 3964)
  AUTHORS   Alsio,J.M., Tarchini,B., Cayouette,M. and Livesey,F.J.
  TITLE     Ikaros promotes early-born neuronal fates in the cerebral cortex
  JOURNAL   Proc Natl Acad Sci U S A 110 (8), E716-E725 (2013)
   PUBMED   23382203
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):E3088. doi:
            10.1073/pnas.1508413112.. PMID: 25976099]
REFERENCE   7  (bases 1 to 3964)
  AUTHORS   Yeung,F., Chung,E., Guess,M.G., Bell,M.L. and Leinwand,L.A.
  TITLE     Myh7b/miR-499 gene expression is transcriptionally regulated by
            MRFs and Eos
  JOURNAL   Nucleic Acids Res 40 (15), 7303-7318 (2012)
   PUBMED   22638570
REFERENCE   8  (bases 1 to 3964)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   9  (bases 1 to 3964)
  AUTHORS   Elliott,J., Jolicoeur,C., Ramamurthy,V. and Cayouette,M.
  TITLE     Ikaros confers early temporal competence to mouse retinal
            progenitor cells
  JOURNAL   Neuron 60 (1), 26-39 (2008)
   PUBMED   18940586
REFERENCE   10 (bases 1 to 3964)
  AUTHORS   Mattar,P., Britz,O., Johannes,C., Nieto,M., Ma,L., Rebeyka,A.,
            Klenin,N., Polleux,F., Guillemot,F. and Schuurmans,C.
  TITLE     A screen for downstream effectors of Neurogenin2 in the embryonic
            neocortex
  JOURNAL   Dev Biol 273 (2), 373-389 (2004)
   PUBMED   15328020
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC156606.12.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK033716.1, SRR7345562.2545375.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142 [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-128               AC156606.12        137955-138082       c
            129-311             AC156606.12        124237-124419       c
            312-494             AC156606.12        121323-121505       c
            495-3964            AC156606.12        116220-119689       c
FEATURES             Location/Qualifiers
     source          1..3964
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 73.98 cM"
     gene            1..3964
                     /gene="Ikzf5"
                     /gene_synonym="2610034F18Rik; PEGASUS; Zfpn1a5"
                     /note="IKAROS family zinc finger 5"
                     /db_xref="GeneID:67143"
                     /db_xref="MGI:MGI:1914393"
     exon            1..128
                     /gene="Ikzf5"
                     /gene_synonym="2610034F18Rik; PEGASUS; Zfpn1a5"
                     /inference="alignment:Splign:2.1.0"
     exon            129..311
                     /gene="Ikzf5"
                     /gene_synonym="2610034F18Rik; PEGASUS; Zfpn1a5"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..979
                     /gene="Ikzf5"
                     /gene_synonym="2610034F18Rik; PEGASUS; Zfpn1a5"
                     /note="isoform 3 is encoded by transcript variant 3; zinc
                     finger protein, subfamily 1A, 5; zinc finger protein
                     Pegasus; ikaros family zinc finger protein 5"
                     /codon_start=1
                     /product="zinc finger protein Pegasus isoform 3"
                     /protein_id="NP_001405691.1"
                     /db_xref="GeneID:67143"
                     /db_xref="MGI:MGI:1914393"
                     /translation="MGEKKPEPLDFVKDFQEYLTQQTHHVNMISGSVSGDKEAETLQG
                     AGTDGDQNGLDHPSVEVSLDENSGMLVDGFERTFDGKLKCRYCNYASKGTARLIEHIR
                     IHTAGQLSSLPPENQNPASPDVDACPDEKPFMIQQPSAQAVVSAVSASIPQSSSPTSP
                     EPRPSHSQRNYSPVAGPSSEPSAHTSTPSIGNSQPSTPAPTLPVQDPQLLHHCQHCDV
                     YFADNVLYTVHMGCHGYDSPFQCNVCGCKCKDKYDFACHFARGQHNQH"
     exon            312..494
                     /gene="Ikzf5"
                     /gene_synonym="2610034F18Rik; PEGASUS; Zfpn1a5"
                     /inference="alignment:Splign:2.1.0"
     exon            495..3964
                     /gene="Ikzf5"
                     /gene_synonym="2610034F18Rik; PEGASUS; Zfpn1a5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2231..2236
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ikzf5"
                     /gene_synonym="2610034F18Rik; PEGASUS; Zfpn1a5"
                     /note="hexamer: AATAAA"
     polyA_site      2250
                     /gene="Ikzf5"
                     /gene_synonym="2610034F18Rik; PEGASUS; Zfpn1a5"
     regulatory      3943..3948
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ikzf5"
                     /gene_synonym="2610034F18Rik; PEGASUS; Zfpn1a5"
                     /note="hexamer: AATAAA"
     polyA_site      3964
                     /gene="Ikzf5"
                     /gene_synonym="2610034F18Rik; PEGASUS; Zfpn1a5"
                     /note="major polyA site"
ORIGIN      
        1 gggaagggag cggagacaca acaaatatgg cggctacagc tgcgacgctg acgaacgctg
       61 aggcggtggc ggtggcggcg acggcagtga aaagggctgt ggggattcct cggtgcggtt
      121 gtcaggagat ataacagact ttcaacttaa agaaagaaag aaaaaaaaaa gcaccaagat
      181 gggtgaaaag aaaccagagc ctttggactt tgtaaaagat ttccaggaat acctgaccca
      241 gcagacgcat catgtgaaca tgatttcggg atcagttagt ggggacaaag aagcagagac
      301 tcttcaggga gctggaacag atggcgatca gaatggcctt gatcacccgt ctgttgaagt
      361 ttccctggat gaaaactcag gaatgttagt agacgggttt gagaggacct tcgatgggaa
      421 gctcaagtgt cggtactgca actatgccag caaaggaacg gccaggctca ttgagcacat
      481 caggatccac acagcaggac agttgtccag cttgccacca gaaaaccaaa accctgcctc
      541 tcctgatgta gatgcctgcc ctgatgaaaa gcctttcatg attcagcaac cctctgccca
      601 agcagttgtc tctgctgtgt cagcaagtat tcctcagagc tcctccccca caagtccgga
      661 accgcggcca tcgcatagtc agaggaacta cagtccagtg gcagggccca gcagtgaacc
      721 aagtgcccac accagtactc ccagcatagg aaacagccag ccaagcactc cagctccaac
      781 cctgccggtg caggatcctc agcttctaca ccactgccag cactgtgacg tgtactttgc
      841 agacaacgtc ctttacactg tccacatggg gtgccatggg tatgacagcc cctttcagtg
      901 taacgtatgt gggtgcaaat gtaaagacaa gtacgatttt gcctgtcatt ttgcaagagg
      961 gcaacacaac cagcactgaa cacaatcaac attgttctca cttggtttgg ccttttggga
     1021 gtttgtagtt tggtttttag tttgatcatc cctaataagg tatatgctaa tttaaaattt
     1081 atacattcta gtctataaaa tagaagtttg atagtgaaaa agggttttgt taacttttca
     1141 taaaagtctg gtcagggtta tttatgcatt agatagttag atgcattgct gtctttttca
     1201 tttacaccta tgagagttaa agtacagttg taatcagttt cctacacttg tccataagga
     1261 ttcccagggt tatctgtact cctgatgctt caggatatac attacagcta atgttctttc
     1321 tgccatatgt caaaatggca cacttctcat aaaatctttt ataacatttc agtgtttata
     1381 gacaaactgc ctttaagttt gctcctaatt aaaatactat tttcattcac ataacttaag
     1441 ttgaattagt ttcattacaa ccaaaaccag tagttatttc agtgtaataa atatttctct
     1501 tcaaggagaa gcataaaaca gttctttcaa atttaaatta taaaatgaaa atcttggaag
     1561 ttgaaatttg gggctaaatt gaaaattgtg tttggtattt gagatatctg ttcatttaat
     1621 gtgtaaacat gttagttttt agcttttcat ttatatatgt atttatatat tttgagtatt
     1681 attttaaagc cacaggtaaa tatactagag tgctagatgc cttttttcaa tctgatcttt
     1741 catgtaaatt ctgcattcac ctgttactgg tgtcaggtaa gattgacagc cacactgatt
     1801 attttattct tcccagtctt tgatgaccaa agaggaagtg agcgcatcat cccactgaga
     1861 tgcttccaga gcctccgagg ctcctttcct gccctctgtg cataattgcc cgtaatgtcc
     1921 acgaagggtt ggtctagaaa cccagagacg taataagtga ggaaacagct acaaacccag
     1981 agcatgccca gacagagcct ccttgcctct ccagagcaga gcaggccatg gaaagtcctc
     2041 cctgtgagtc tttatggaca gagacggtgg gatcgtcacc acagtgggaa aggataaata
     2101 gagttattat gaagcacatt taaatgtgtc atttaactta cttagaatta gagtggttca
     2161 ttttatatag gaagccatta tttttgtatt gtgtaataag tagcttactc tgaagagagc
     2221 ctggcaaaac aataaaacat tgtcacttac tattggtttc tgtgtacctt gcaaattttt
     2281 catttttatt tggttaatag cttgaaaata ttctcaattg gcttcttaaa gaaataccct
     2341 gtcaagcatt tattaaccaa aaaatagcct cttacagtaa ataagaggga actatgagag
     2401 tgtctacccg tgaagcccca agtgccctgg taatggacct gctctccctc cctgtgctgg
     2461 aaagccattc cgagggtgcc tgtgcgtaca cagccagtct tggctcctcc caactgcact
     2521 gttaaagcgc agccccgaag acactttcta gtgattttgg tctgttgctt aaatcattta
     2581 ctagattagt tttagggcaa cactttccaa atacataact tgactgttgt gcttatcagc
     2641 tgccagaaag aaacaggtta ttgttgggaa accttgctgt ttttaaagtt tgattcaatt
     2701 aaaagcaata cttccaaata gacagtgaaa acttcccaaa agaggaagaa gcccagtgta
     2761 ctgccgcaca tctgtagtcc cagctgcttg aagcagaggc gggaagagtg ctagagccca
     2821 ggaggtccct gccaggccgg gcaacactgc aagacacagt ctcaaaggcc aagcagccga
     2881 aagggctctc ctcacagcca gctttatcac ctctacgttc tgggccaaac agtgacatgg
     2941 gcattttggt tttcctaaca actaacgatg aatgttctga aggtacattt cattttaaat
     3001 acggaaaaaa cttttcataa ttacagacaa gaaggaaaaa cccccgattt tccaataata
     3061 taaagagcac agttggtctt ccaaaggtgt ccatgtgtga agctacaagt acttcgaaat
     3121 gcactaaaat tttgaagcaa atctacctta ggaacttttt tgaaattgta cttttaaagg
     3181 tttaggcttt tgcttaaata ttctgagtta aattctgtac taggaaagat gttggattct
     3241 ttccttaaat actaaataag ttcctcatct tatttttaat caaatgtttt atagaaatga
     3301 gttgagaaaa gttgaccatg cactatttat agtactttgc cataacaggc aatgttctaa
     3361 aactaaattt atttttgttt agtgaacatg agtttagatt tttaaagttg gtaatttatc
     3421 tccactaata tttttttaaa gaaactgtga agagattaac agaataattt tatttcagat
     3481 tttactaatg tagtgtgtag ctacaacttg acattcaagt gaagactaga cttctgtttt
     3541 gaaatttttc catcaggtag tttcagtggt ttcattttag aaatgtgttt gcagatgttt
     3601 gacaaaggga atattactaa aaaagaaaag caaaaaaaaa aaaaacttat caaatgaaga
     3661 attgttagaa aaatttaaat tccctgctaa agacattttt gttagtctta gggggtaggt
     3721 atttgctttc tagaacttgt ttttgttgat agtatttgct ttctagaact tgtttttgtt
     3781 gatagctgga tgtatggaac ctgttttcta tgcgaggtgc aagtcttgca ctacagttgt
     3841 aagatatatt atattgttta gggatcaaga aagcaatcta tgctgaagta actatagtat
     3901 gtagttccta ttgtgaataa tgctttgctt ttgtaatgta ttaataaaaa gtaacacttt
     3961 ctaa
//
