LOCUS       NM_001161421            6915 bp    mRNA    linear   ROD 11-MAR-2025
DEFINITION  Mus musculus inhibitor of kappaB kinase gamma (Ikbkg), transcript
            variant 4, mRNA.
ACCESSION   NM_001161421
VERSION     NM_001161421.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6915)
  AUTHORS   De Ponti,F.F., Bujko,A., Liu,Z., Collins,P.J., Schuermans,S.,
            Maueroder,C., Amstelveen,S., Thone,T., Martens,L., McKendrick,J.G.,
            Louwe,P.A., Sanchez Cruz,A., Saelens,W., Matchett,K.P.,
            Waller,K.J., Zwicker,C., Buglar-Lamb,A., Vanneste,B.,
            Parmentier,F., Binte Abdul Latib,M., Remmerie,A., Kertesz,L.,
            Kremer,A., Verbeke,J., Ipsen,D.H., Pfister,D.R., Liu,Z.,
            Guilliams,M., Henderson,N.C., Ravichandran,K., Marques,P.E. and
            Scott,C.L.
  TITLE     Spatially restricted and ontogenically distinct hepatic macrophages
            are required for tissue repair
  JOURNAL   Immunity 58 (2), 362-380 (2025)
   PUBMED   39862865
REFERENCE   2  (bases 1 to 6915)
  AUTHORS   Tsesmelis,M., Buttner,U.F.G., Gerstenlauer,M., Manfras,U.,
            Tsesmelis,K., Du,Z., Sperb,N., Weissinger,S.E., Moller,P.,
            Barth,T.F.E., Maier,H.J., Chan,L.K. and Wirth,T.
  TITLE     NEMO/NF-kappaB signaling functions as a double-edged sword in PanIN
            formation versus progression to pancreatic cancer
  JOURNAL   Mol Cancer 23 (1), 103 (2024)
   PUBMED   38755681
  REMARK    GeneRIF: NEMO/NF-kappaB signaling functions as a double-edged sword
            in PanIN formation versus progression to pancreatic cancer.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6915)
  AUTHORS   Harding,O., Holzer,E., Riley,J.F., Martens,S. and Holzbaur,E.L.F.
  TITLE     Damaged mitochondria recruit the effector NEMO to activate
            NF-kappaB signaling
  JOURNAL   Mol Cell 83 (17), 3188-3204 (2023)
   PUBMED   37683611
  REMARK    GeneRIF: Damaged mitochondria recruit the effector NEMO to activate
            NF-kappaB signaling.
REFERENCE   4  (bases 1 to 6915)
  AUTHORS   Tang,X., Weng,R., Guo,G., Wei,J., Wu,X., Chen,B., Liu,S., Zhong,Z.
            and Chen,X.
  TITLE     USP10 regulates macrophage inflammation responses via stabilizing
            NEMO in LPS-induced sepsis
  JOURNAL   Inflamm Res 72 (8), 1621-1632 (2023)
   PUBMED   37436447
  REMARK    GeneRIF: USP10 regulates macrophage inflammation responses via
            stabilizing NEMO in LPS-induced sepsis.
REFERENCE   5  (bases 1 to 6915)
  AUTHORS   Vucur,M., Ghallab,A., Schneider,A.T., Adili,A., Cheng,M.,
            Castoldi,M., Singer,M.T., Buttner,V., Keysberg,L.S., Kusgens,L.,
            Kohlhepp,M., Gorg,B., Gallage,S., Barragan Avila,J.E., Unger,K.,
            Kordes,C., Leblond,A.L., Albrecht,W., Loosen,S.H., Lohr,C.,
            Jordens,M.S., Babler,A., Hayat,S., Schumacher,D., Koenen,M.T.,
            Govaere,O., Boekschoten,M.V., Jors,S., Villacorta-Martin,C.,
            Mazzaferro,V., Llovet,J.M., Weiskirchen,R., Kather,J.N.,
            Starlinger,P., Trauner,M., Luedde,M., Heij,L.R., Neumann,U.P.,
            Keitel,V., Bode,J.G., Schneider,R.K., Tacke,F., Levkau,B.,
            Lammers,T., Fluegen,G., Alexandrov,T., Collins,A.L., Nelson,G.,
            Oakley,F., Mann,D.A., Roderburg,C., Longerich,T., Weber,A.,
            Villanueva,A., Samson,A.L., Murphy,J.M., Kramann,R., Geisler,F.,
            Costa,I.G., Hengstler,J.G., Heikenwalder,M. and Luedde,T.
  TITLE     Sublethal necroptosis signaling promotes inflammation and liver
            cancer
  JOURNAL   Immunity 56 (7), 1578-1595 (2023)
   PUBMED   37329888
REFERENCE   6  (bases 1 to 6915)
  AUTHORS   Maniatis,T.
  TITLE     A ubiquitin ligase complex essential for the NF-kappaB,
            Wnt/Wingless, and Hedgehog signaling pathways
  JOURNAL   Genes Dev 13 (5), 505-510 (1999)
   PUBMED   10072378
  REMARK    Review article
REFERENCE   7  (bases 1 to 6915)
  AUTHORS   Li,Y., Kang,J., Friedman,J., Tarassishin,L., Ye,J., Kovalenko,A.,
            Wallach,D. and Horwitz,M.S.
  TITLE     Identification of a cell protein (FIP-3) as a modulator of
            NF-kappaB activity and as a target of an adenovirus inhibitor of
            tumor necrosis factor alpha-induced apoptosis
  JOURNAL   Proc Natl Acad Sci U S A 96 (3), 1042-1047 (1999)
   PUBMED   9927690
REFERENCE   8  (bases 1 to 6915)
  AUTHORS   Mercurio,F., Murray,B.W., Shevchenko,A., Bennett,B.L., Young,D.B.,
            Li,J.W., Pascual,G., Motiwala,A., Zhu,H., Mann,M. and Manning,A.M.
  TITLE     IkappaB kinase (IKK)-associated protein 1, a common component of
            the heterogeneous IKK complex
  JOURNAL   Mol Cell Biol 19 (2), 1526-1538 (1999)
   PUBMED   9891086
REFERENCE   9  (bases 1 to 6915)
  AUTHORS   Yamaoka,S., Courtois,G., Bessia,C., Whiteside,S.T., Weil,R.,
            Agou,F., Kirk,H.E., Kay,R.J. and Israel,A.
  TITLE     Complementation cloning of NEMO, a component of the IkappaB kinase
            complex essential for NF-kappaB activation
  JOURNAL   Cell 93 (7), 1231-1240 (1998)
   PUBMED   9657155
REFERENCE   10 (bases 1 to 6915)
  AUTHORS   Verma,I.M., Stevenson,J.K., Schwarz,E.M., Van Antwerp,D. and
            Miyamoto,S.
  TITLE     Rel/NF-kappa B/I kappa B family: intimate tales of association and
            dissociation
  JOURNAL   Genes Dev 9 (22), 2723-2735 (1995)
   PUBMED   7590248
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AY112937.1, AK037020.1 and AL669976.11.
            
            Transcript Variant: This variant (4) uses an alternate in-frame
            splice junction at the 5' end of an exon compared to variant 3. The
            resulting isoform (4) has the same N- and C-termini but is 1 aa
            shorter compared to isoform 3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC021431.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-659               AY112937.1         1-659
            660-1649            AK037020.1         535-1524
            1650-6915           AL669976.11        27716-32981
FEATURES             Location/Qualifiers
     source          1..6915
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 38.0 cM"
     gene            1..6915
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /note="inhibitor of kappaB kinase gamma"
                     /db_xref="GeneID:16151"
                     /db_xref="MGI:MGI:1338074"
     exon            1..104
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /inference="alignment:Splign:2.1.0"
     exon            105..245
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /inference="alignment:Splign:2.1.0"
     CDS             207..1496
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /note="isoform 4 is encoded by transcript variant 4;
                     NF-kappa-B essential modulator; inhibitor of nuclear
                     factor kappa-B kinase subunit gamma; IKKG; IKKAP1; mFIP-3;
                     IKK-gamma; ikB kinase subunit gamma; NF-kappa-B essential
                     modifier; I-kappa-B kinase subunit gamma; ikB
                     kinase-associated protein 1; inhibitor of kappa light
                     polypeptide gene enhancer in B-cells, kinase gamma"
                     /codon_start=1
                     /product="NF-kappa-B essential modulator isoform 4"
                     /protein_id="NP_001154893.1"
                     /db_xref="GeneID:16151"
                     /db_xref="MGI:MGI:1338074"
                     /translation="MYIRYCCDDQDTQTLSCWMNKHPWKNQLSEMVQPSGGPAEDQDM
                     LGEESSLGKPAMLHLPSEQGTPETLQRCLEENQELRDAIRQSNQMLRERCEELLHFQV
                     SQREEKEFLMCKFQEARKLVERLSLEKLDLRSQREQALKELEQLKKCQQMAEDKASVK
                     AQVTSLLGELQESQSRLEAATKDRQALEGRIRAVSEQVRQLESEREVLQQQHSVQVDQ
                     LRMQNQSVEAALRMERQAASEEKRKLAQLQAAYHQLFQDYDSHIKSSKGMQLEDLRQQ
                     LQQAEEALVAKQELIDKLKEEAEQHKIVMETVPVLKAQADIYKADFQAERHAREKLVE
                     KKEYLQEQLEQLQREFNKLKVGCHESARIEDMRKRHVETPQPPLLPAPAHHSFHLALS
                     NQRRSPPEEPPDFCCPKCQYQAPDMDTLQIHVMECIE"
     exon            246..447
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /inference="alignment:Splign:2.1.0"
     exon            448..659
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /inference="alignment:Splign:2.1.0"
     exon            660..775
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /inference="alignment:Splign:2.1.0"
     exon            776..928
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1004
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /inference="alignment:Splign:2.1.0"
     exon            1005..1148
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /inference="alignment:Splign:2.1.0"
     exon            1149..1291
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /inference="alignment:Splign:2.1.0"
     exon            1292..1353
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /inference="alignment:Splign:2.1.0"
     exon            1354..6915
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3405..3410
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /note="hexamer: AATAAA"
     polyA_site      3427
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
     regulatory      4638..4643
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /note="hexamer: AATAAA"
     polyA_site      4662
                     /gene="Ikbkg"
                     /gene_synonym="1110037D23Rik; IKK[g]; NEMO"
                     /note="major polyA site"
ORIGIN      
        1 cttgttctct ttgggattaa caagacatag aacctgctct ccttgttttg gctcagcctg
       61 caactgacag tctgcctggc ttcaagtcac ccaagggagg tgaggaggaa gaagtgctac
      121 tgggtggtgc tttagcacct gtgatggtcc aagtctggtc tccactcaat ggctcagcac
      181 agagttctga gatgtgacac aagtacatgt atatcaggta ctgctgtgat gatcaggaca
      241 cacagacact gtcctgttgg atgaacaagc acccctggaa gaaccagctg agtgagatgg
      301 tgcagcccag tggtggccca gcagaggacc aggacatgct gggtgaagaa tcttctctgg
      361 ggaagcctgc aatgctacat ctgccttcag agcagggtac tcctgagacc ctccagcgct
      421 gcctggaaga gaatcaagag ctccgagacg ctatccggca gagcaatcag atgctgaggg
      481 aacgctgtga ggagctgctg catttccagg tcagccagcg ggaggagaag gagttcctta
      541 tgtgcaaatt ccaggaagcc cggaagctgg tggagagact gagcttggag aagcttgatc
      601 ttcggagtca gagggaacag gccttaaagg agttggagca actgaagaaa tgccaacaga
      661 tggctgagga caaggcctct gtgaaagctc aggtgacatc attgctcgga gaactccagg
      721 agagccagag ccgtttggag gctgccacca aggatcggca agctttagag ggaaggattc
      781 gagcagttag tgagcaggtc agacagctgg agagtgagcg ggaggtgcta cagcagcagc
      841 acagcgtcca ggtggaccag ctgcgtatgc agaaccagag cgtggaggct gccttgcgaa
      901 tggagcggca ggctgcttca gaggagaagc ggaagctggc tcagttgcag gcagcctatc
      961 accagctctt ccaagactac gacagccaca ttaagagcag caagggcatg cagctggaag
     1021 atctgaggca acagctccag caagctgagg aggccctggt agccaaacag gaattgattg
     1081 ataagctgaa agaggaggct gagcagcaca agattgtgat ggagactgtg ccagtcttga
     1141 aggcccaggc ggatatctac aaggctgact tccaagctga gaggcatgcc cgggagaagc
     1201 tggtggagaa gaaggagtat ttgcaggagc agctggagca gctgcagcgc gagttcaaca
     1261 agctgaaagt tggctgccat gagtcagcca ggattgagga tatgaggaag cggcatgtag
     1321 agactcccca gcctccttta ctccctgctc cagctcacca ctcctttcat ttggccttgt
     1381 ccaaccagcg gaggagccct cctgaagaac ctcctgactt ctgttgtccg aagtgccagt
     1441 atcaggctcc tgatatggac actctacaga tacatgtcat ggagtgcata gagtaggagc
     1501 agcagatgca aggccacttg cagtactatg tcctgatctg tgtgacttgt gctttcctgt
     1561 tttacctgca tagtccacac ttaagggctt gctttagccc tttggtcccc catttagggt
     1621 agacagcccc attcagggct tttttttttc tgtgtgcctg atccagtttg cctctggtgg
     1681 cttcttccct cttctcccat agtcctaggg agtctagaat ggaggccagg ggctcttagg
     1741 gagcatccct tctccaagca ggtctgggta cagcttttct tctctccaac tggtaccttt
     1801 cttgccggtg aactgcaggc tctcctccca gggcatgtgg cacttgggtc tataacatgt
     1861 gttacctctg gtagacatgt ggaaagtatt ctgtcctttt gttactgtaa ttaatggtgt
     1921 agtgaaagta cttgtacact gatctgtgtg tacctttagg acagatgctt agatgtgaca
     1981 ttggatcctt gccctggagg aggtgggcag acctttggat ttttgccatc tctaagatat
     2041 accattcttt actaaagaat ttgcttaagt gtctttttct ggggcatgtg ggcccttttt
     2101 aattcctctg atgtaacttg gattttcata attcctaccc atttttctgt tgggacattg
     2161 ccatttgttc ttgggctttg tagagctttt tgattatcag tcaggttggt tttgactatt
     2221 acagaagtgc accccttgtt ccacattgat tgttagtgtt ttggggccta gaagctgttt
     2281 tatactccta cttacccatt ctttactcct agttttttga ctttggaatt atgactgctt
     2341 tgtcaacaga aaggtatttc acatgtatgc tttccttttt ctagccccag tgtgctcttg
     2401 tttttgccaa gcacattgtt accttctgtg aatggtggtg gccatagttc atcacactcc
     2461 tggagtttgt gatcacatgt tcttcaccag ccaaaatgtc ctagggaacc atttagcagt
     2521 gactgactga tcacagaaaa gggaacactt cacttgtttt gcaaggttct agacattttg
     2581 tgggacctta ccgtcattgg tattagacct gcagttctag taaaggaaag gaagttgtag
     2641 ttgagaaagc aataaatatg ccttgctcat tccttaggtc taaatccttc ctgccctcct
     2701 gtaagctttc atggttctga gtggtatctg tgaatccatc ccgggggctt ttatttacat
     2761 ggtttctttc ccattaagag tgagaaggct aagtagaatt cagattataa aaaaggattt
     2821 aaaaagtaat cctgagctgg gggctttctc ggaattttca ggggatgcag agtaagtttt
     2881 ccatttccta attcccaggt atctatcaga aagatcttta ggaaaatgtt aaaggaacaa
     2941 acaagttctt tgcttatgtg ttttcattta aatacctaat ctataatttt cctttaggaa
     3001 tactattggt ttaggttgag tccagttttg tggtggtata tatcactttt ctatagctgc
     3061 tttaaaattt ttcctaaact tggaagagca agaacaacaa caacaacaac aacaacaaca
     3121 aatcactctt tcctgtctgg aagccacata ttaagttttt tctggaggct gtgagaatca
     3181 attccaggca ttctcttaac tttcagtggt ttgtggtagt ccttggtgtt gcttggctca
     3241 tagacccatc actccagttt ctggttctag ggccttgtgg tttcttcctc tcttctgtct
     3301 cataaggaaa ccatgttgtg catgtggggt ctatttgatt agattaagga ggatctccag
     3361 ttcaagaccc ttaactcatt ccacctacca agatcctttc cccaaataaa gtcttgttct
     3421 cacattatgg gggtttgggc ttatataacc cggagtatgg atatcatcag aacctgagta
     3481 aatgcagccc aaaggcaggg cctttaaagc cttgtaattc tgctagagag acctggtctc
     3541 tagggtgatg accagtagtc ttcagagttt gaaggcagac ccttgtcagt gcttgatgct
     3601 gttagtaggg tcagtgggaa tgattgggaa aggcaggttg gctatagtag gagagagctg
     3661 ttgggctgcc tgcagtggct gcatgagctt cacgcttctt ggataaacag agatgcatag
     3721 gtgcatttct gaccagtact ttatcctgaa agggtcccag aaagcaggtg tgacccaggt
     3781 tacacagtag gaagcttgaa aacatgggct tcatgcactg gtcaagacaa atctgagggt
     3841 ggcacaaggt aatggttggg acctagtacc cttctagaag gtgggagccc ttgccaccga
     3901 cttaccctgc agtatggtgt atgattaacc gtacatcaaa gatttgagat tctaccatct
     3961 ttttgacatg agacatgctc ttttcttttg cagaattact taagctagaa ctggaaaaag
     4021 tggtcgttcc attcccctca ggaattagtc tacttgcttt tgcacaaatt ttatgtggcc
     4081 tctggcagac aacttttaga tccatacagc tagaagcatg ccctttccag aagacctgtt
     4141 ctggaataga tagtgcttct tatgtatgct ctcttcctgt tggcccatgc ccaagagaaa
     4201 accagagagc cagtaagaca gtacagagtg cttcacctac tgaagtaata aacgataagg
     4261 cagattgtag gtaggaatga tatctaaaaa ggaacaattg cagccctgtg tgtgacaccc
     4321 tcaggcaagg taaggcctac cttttagtgt ttcccctttc aaggtgggag tttggagaga
     4381 tgaacaagca ctttggaagc atccccagcc ctctttacct gacaacagtt tggtcctcac
     4441 agtgactgct tcattggagt gcctctccag tgttatggca ccatcatctg ttaccaccca
     4501 aggctgtgat gaaataagat acaacatatc cgatgacaca ggcctgcatg gctagcatct
     4561 tgaacatttt attacatgaa cattctctgt acgatggtat aaaaaggccc gaggattaaa
     4621 ttatgtataa aatatgaaat aaagaagtaa gactttcaag catgcactct gtcctccctt
     4681 gttggatgta ggggtaggat tgccagtaac aaaggttttc tttgctattt ctatctcttt
     4741 aattcccctg tattacatag gaagtagctg ttacacacag ctctgaggtt tcttctgcct
     4801 atggctgagg aaagctcatt attgacacaa cagagtggtg aaaggggcca agtcaactaa
     4861 tttggggctt gaatttcctg tggttgcagc aacaaagtac cacacgttag ggagcttagg
     4921 caacagattt cctctccctg ttaaggatgg caggcatctg agaagtgggt tcctcataag
     4981 ggataaccca ttccagtgcc cctctccagt gtgtggcagg tcccagaaat tcttagtttt
     5041 ctctagttgt acctgcatct ctgcctctgc cacttttgtc acatggccat cttgtgtttc
     5101 ctttttataa gcacaccagt gttgtataca ggtgggtatt tggaaacatg gaagcatttt
     5161 gttcagtatc tagtgacagt gatggaaaga gatgatttgc agagaaggtc agagcagcat
     5221 gagggtctta ggtatggagc tgcagccaac attatggaca tggaagagag ggattgctgg
     5281 acttttggtt tcctgcctgg gtacctggac aatctatcta ccattgggag gactaggtaa
     5341 cagtggaagt tagttatgag agaagttgtt tgatgttcaa ttctgatcta gccaggctca
     5401 gtgtgagatg tcctgggtcc cttcatcttg ccttgactgt taggtgcagt ttcatattga
     5461 aactgcaggc tcttttttat ccattgctac tggcaaccag tgtgatctgg taaatctgtt
     5521 tccactttgc ttagtgctct ccactgattt tctgttactt gagacctaaa ctccatcttc
     5581 agccttgtgt tgatctaatg tcatgtcaac ttctctaaaa gctcagccaa ttctacactg
     5641 gccttctatt cctttcctca aaccacttag cacttttttt ttttaaattt ttttagattt
     5701 atttatttat ttattatatg taagtacact gtagttgtct tcagacactc cagaaaagga
     5761 gtcagatctt gttacggatg gttgtgagcc accatgtggt tgctgggatt tgaactccag
     5821 acctttggaa gagcagtagg gtgctcttac ccactgagcc atctcaccag cccagcactt
     5881 ctgtttctta aggctgttgc tcctgttgtc tcctttgctg agaaagttct gttccctaat
     5941 ttgtactgtt gactactttt tgtcatccat ataagtgtaa acaaaagttc tttcatctga
     6001 tctcttcatc ctaaatcata ctaccctgtt ttaactcaca ttactaccac tgaccttttc
     6061 tagtgttttt ttcttttcta ccactagagg gagacagaag ccgtatcaat ttagtcgtat
     6121 actcaacaca gggaaactgc atttactgat ggctgagctt gtctgagacg atatcaggat
     6181 tcccctgcca atatcttcat ggacgtcact tgtcaccata attggtgact tatagaagtt
     6241 attaatgtac tagaaattat agtacagaaa tcttatttta ggactatagt accaatagcc
     6301 tttttttgtg gtgctgggga tagaacccag ggtctttcac atgtaagcat tcataccatc
     6361 actgagctac aatccctggt tatcagcttc tcactttatt taccttcccc tgactttgac
     6421 agccctgtct agtttggaac ttattatgta atccacgatg gccttgaatt tacagccatc
     6481 ctcagcctct ccagtgctag gattataaat atatctgact agcttatttt tttcattttg
     6541 ttcaggtttt taatgagtgt cttggtttca gatatgaaaa acagaatttg gaagaaagcc
     6601 agttgggcca gtctgtggta gagcatgcac tcaaagttga agcaagatgt taatgagttc
     6661 taggctggct taggcttcat agcaagatcc tatctcataa aacaaaaagt taactggtga
     6721 ttccctggag gtgagagggg tgaggagaga gtgatagtta atgaatacaa agttctttga
     6781 gggaaaatga gaatattctg aaattggcta tggcgatact catacatttg tgaatgtgca
     6841 aggaacactt cagatgaatg acttttgttg tatatggatt aggttgcaat aaaactggca
     6901 tttaaaatgt tatct
//
