LOCUS       XM_006509023            1468 bp    mRNA    linear   ROD 10-APR-2023
DEFINITION  PREDICTED: Mus musculus inhibitor of kappaB kinase beta (Ikbkb),
            transcript variant X8, mRNA.
ACCESSION   XM_006509023
VERSION     XM_006509023.5
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000074.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Oct 12, 2023 this sequence was replaced by
            NR_188955.1.
            
            On Sep 21, 2020 this sequence version replaced XM_006509023.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2023_04
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 04/05/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1468
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="8"
     gene            1..1468
                     /gene="Ikbkb"
                     /gene_synonym="IKK-2; IKK-beta; IKK2; IKKbeta; IKK[b]"
                     /note="inhibitor of kappaB kinase beta; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 9 mRNAs, 9 ESTs, 186 long SRA reads, and 100% coverage
                     of the annotated genomic feature by RNAseq alignments,
                     including 30 samples with support for all annotated
                     introns"
                     /db_xref="GeneID:16150"
                     /db_xref="MGI:MGI:1338071"
     CDS             139..1383
                     /gene="Ikbkb"
                     /gene_synonym="IKK-2; IKK-beta; IKK2; IKKbeta; IKK[b]"
                     /codon_start=1
                     /product="inhibitor of nuclear factor kappa-B kinase
                     subunit beta isoform X6"
                     /protein_id="XP_006509086.1"
                     /db_xref="GeneID:16150"
                     /db_xref="MGI:MGI:1338071"
                     /translation="MSWSPSLPTQTCGAWEMKERLGTGGFGNVIRWHNQATGEQIAIK
                     QCRQELSPKNRDRWCLEIQIMRRLNHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGG
                     DLRRYLNQFENCCGLREGAVLTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEKRL
                     IHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITG
                     FRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGAVKFSSSLPFPNNLNSVLAERLEKW
                     LQLMLMWHPRQRGTDPQYGPNGCFRALDDILNLKLVHVLNMVTGTVHTYPVTEDESLQ
                     SLKTRIQEDTGILETDQELLQEAGLVLLPDKPATQCISDSKTNEGLTLDMDLVFLFDN
                     SKINYETQITPRPQPESVSCIR"
ORIGIN      
        1 gtacccgtga cgtcagggca ggaagtgttt gaggaagtgg cgctgggctg gctgcgtggg
       61 gaccccgagt tttcatgtcc tcagcgggtg tcgctggcgg ccccgcggcc cccggggcag
      121 agttagcagg gcatcgatat gagctggtca ccgtccctcc caacccagac atgtggagcc
      181 tgggaaatga aagaacgcct ggggaccggg ggatttggaa acgtcatccg gtggcacaat
      241 caggcgacag gtgaacagat cgccatcaag caatgccgac aggagctcag cccaaagaac
      301 agagaccgct ggtgcctcga aatccagatc atgagaaggc tgaaccatcc caatgtggtg
      361 gctgcccggg atgtcccaga ggggatgcag aacctggcac ccaatgattt gccactgctg
      421 gccatggagt actgccaagg aggagatctc cgaagatact tgaaccagtt cgagaactgc
      481 tgtggcctgc gggaaggagc tgtccttacc ctgctgagtg acatcgcatc ggctcttaga
      541 taccttcacg aaaacagaat catccatcga gacctgaagc cagaaaacat cgttctgcag
      601 caaggagaga aaagattaat acacaaaatt attgatctag gatatgccaa ggagctggat
      661 cagggcagtc tgtgcacgtc atttgtgggg actctgcaat acctggcgcc agagcttctg
      721 gagcagcaga agtacaccgt gaccgttgac tactggagct tcggcaccct ggccttcgag
      781 tgcatcactg gcttccggcc cttcctccct aactggcagc ctgtgcagtg gcactccaaa
      841 gtccggcaga agagcgaagt ggacatcgtt gttagtgaag acttgaatgg agcagtgaag
      901 ttttcaagtt cgctaccctt ccccaataat cttaacagtg tcttggctga acggctggag
      961 aagtggctgc agctgatgct tatgtggcac cctcggcaaa ggggcacgga tccccagtat
     1021 ggccccaacg gctgcttcag agccctggat gacatcttga acttgaagct ggttcatgtc
     1081 ttgaacatgg tcacaggcac cgttcacaca taccccgtga cggaggatga gagtctgcag
     1141 agcttaaaaa ccagaatcca ggaagacacg gggatcctgg agacagacca ggagctgctg
     1201 caagaggcag ggctggtgct gctccctgac aagcctgcta ctcagtgcat ctcagacagc
     1261 aagacaaacg agggcctcac gttggacatg gatcttgttt ttctctttga caacagtaaa
     1321 atcaactatg agactcagat caccccccga ccccaaccgg aaagtgtcag ctgtatccga
     1381 tgagtctcct ccggaataac agctgcctct ctaagatgaa gaacgccatg gcctccacgg
     1441 cccagcagct caaggccaag ctggactt
//
