LOCUS       XM_006509020            3500 bp    mRNA    linear   ROD 10-APR-2023
DEFINITION  PREDICTED: Mus musculus inhibitor of kappaB kinase beta (Ikbkb),
            transcript variant X2, mRNA.
ACCESSION   XM_006509020
VERSION     XM_006509020.5
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000074.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Oct 12, 2023 this sequence was replaced by
            NM_001424831.1.
            
            On Sep 21, 2020 this sequence version replaced XM_006509020.4.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2023_04
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 04/05/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3500
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="8"
     gene            1..3500
                     /gene="Ikbkb"
                     /gene_synonym="IKK-2; IKK-beta; IKK2; IKKbeta; IKK[b]"
                     /note="inhibitor of kappaB kinase beta; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 12 mRNAs, 34 ESTs, 712 long SRA reads, 2 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 27 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:16150"
                     /db_xref="MGI:MGI:1338071"
     CDS             139..2259
                     /gene="Ikbkb"
                     /gene_synonym="IKK-2; IKK-beta; IKK2; IKKbeta; IKK[b]"
                     /codon_start=1
                     /product="inhibitor of nuclear factor kappa-B kinase
                     subunit beta isoform X2"
                     /protein_id="XP_006509083.1"
                     /db_xref="GeneID:16150"
                     /db_xref="MGI:MGI:1338071"
                     /translation="MSWSPSLPTQTCGAWEMKERLGTGGFGNVIRWHNQATGEQIAIK
                     QCRQELSPKNRDRWCLEIQIMRRLNHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGG
                     DLRRYLNQFENCCGLREGAVLTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEKRL
                     IHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITG
                     FRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGAVKFSSSLPFPNNLNSVLAERLEKW
                     LQLMLMWHPRQRGTDPQYGPNGCFRALDDILNLKLVHVLNMVTGTVHTYPVTEDESLQ
                     SLKTRIQEDTGILETDQELLQEAGLVLLPDKPATQCISDSKTNEGLTLDMDLVFLFDN
                     SKINYETQITPRPQPESVSCILQEPKRNLSFFQLRKVWGQVWHSIQTLKEDCNRLQQG
                     QRAAMMSLLRNNSCLSKMKNAMASTAQQLKAKLDFFKTSIQIDLEKYKEQTEFGITSD
                     KLLLAWREMEQAVEQCGRENDVKHLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQ
                     ARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALE
                     LLPKVEEVVSLMNEDERTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNVSRLS
                     HPGQLMSQPSSACDSLPESDKKRL"
ORIGIN      
        1 gtacccgtga cgtcagggca ggaagtgttt gaggaagtgg cgctgggctg gctgcgtggg
       61 gaccccgagt tttcatgtcc tcagcgggtg tcgctggcgg ccccgcggcc cccggggcag
      121 agttagcagg gcatcgatat gagctggtca ccgtccctcc caacccagac atgtggagcc
      181 tgggaaatga aagaacgcct ggggaccggg ggatttggaa acgtcatccg gtggcacaat
      241 caggcgacag gtgaacagat cgccatcaag caatgccgac aggagctcag cccaaagaac
      301 agagaccgct ggtgcctcga aatccagatc atgagaaggc tgaaccatcc caatgtggtg
      361 gctgcccggg atgtcccaga ggggatgcag aacctggcac ccaatgattt gccactgctg
      421 gccatggagt actgccaagg aggagatctc cgaagatact tgaaccagtt cgagaactgc
      481 tgtggcctgc gggaaggagc tgtccttacc ctgctgagtg acatcgcatc ggctcttaga
      541 taccttcacg aaaacagaat catccatcga gacctgaagc cagaaaacat cgttctgcag
      601 caaggagaga aaagattaat acacaaaatt attgatctag gatatgccaa ggagctggat
      661 cagggcagtc tgtgcacgtc atttgtgggg actctgcaat acctggcgcc agagcttctg
      721 gagcagcaga agtacaccgt gaccgttgac tactggagct tcggcaccct ggccttcgag
      781 tgcatcactg gcttccggcc cttcctccct aactggcagc ctgtgcagtg gcactccaaa
      841 gtccggcaga agagcgaagt ggacatcgtt gttagtgaag acttgaatgg agcagtgaag
      901 ttttcaagtt cgctaccctt ccccaataat cttaacagtg tcttggctga acggctggag
      961 aagtggctgc agctgatgct tatgtggcac cctcggcaaa ggggcacgga tccccagtat
     1021 ggccccaacg gctgcttcag agccctggat gacatcttga acttgaagct ggttcatgtc
     1081 ttgaacatgg tcacaggcac cgttcacaca taccccgtga cggaggatga gagtctgcag
     1141 agcttaaaaa ccagaatcca ggaagacacg gggatcctgg agacagacca ggagctgctg
     1201 caagaggcag ggctggtgct gctccctgac aagcctgcta ctcagtgcat ctcagacagc
     1261 aagacaaacg agggcctcac gttggacatg gatcttgttt ttctctttga caacagtaaa
     1321 atcaactatg agactcagat caccccccga ccccaaccgg aaagtgtcag ctgtatcctt
     1381 caggagccca agcggaacct ctccttcttc cagctgagga aagtgtgggg ccaagtctgg
     1441 cacagcatcc agacgctgaa ggaagactgt aaccggctgc agcagggaca gcgagcagcc
     1501 atgatgagtc tcctccggaa taacagctgc ctctctaaga tgaagaacgc catggcctcc
     1561 acggcccagc agctcaaggc caagctggac ttcttcaaaa ccagcatcca gatcgacctg
     1621 gagaagtata aagagcagac cgagtttggg atcacctcag ataaattgct gctggcttgg
     1681 cgggagatgg agcaggctgt ggagcagtgt gggcgggaga atgacgtgaa gcatctagta
     1741 gagcggatga tggcactgca gactgacatt gtggacctgc agaggagccc gatgggtcgg
     1801 aagcaggggg gcaccctgga tgacctagag gaacaagcga gggagctcta ccgaagactc
     1861 agggagaagc caagagacca aaggacagaa ggtgacagcc aggagatggt acggctgctg
     1921 cttcaggcaa tccaaagctt tgagaagaaa gttcgggtga tttatacaca gctcagtaag
     1981 accgtggttt gtaagcagaa ggcactggag ttgctgccca aggtagaaga ggtagtgagc
     2041 cttatgaacg aggacgagag gaccgtggtc cggcttcagg agaagcggca gaaggaactc
     2101 tggaacctcc tgaagatcgc ctgtagcaaa gtccgaggtc ccgtgagtgg aagcccagac
     2161 agcatgaatg tgtctcgact cagtcaccct ggtcagctaa tgtcccagcc ttccagtgcc
     2221 tgtgacagct tacctgaatc agacaagaaa agactctaga ctggagctgg ttacagatgg
     2281 aggatgaaga aaggtgtagc ctggagcagg cctgtgactg aggtgcccat gagctggccc
     2341 gtggctctgc atgtgacgat gttctggtat ctccaggtgg acatctcact ctgccagcag
     2401 ctgtgatact tgcccgcagc agcctaggct ggccctgtcc acacactgga ttctcgccca
     2461 cagaagcaca acaatgcagg tacaagcact tgcagcagcg acgcttcatg gctgctgtac
     2521 aaagaaagcg acacagagaa atgacaagtg tctatcttga gtgtttccag acagcagaca
     2581 gcctgtctgc tttggactcc tgggggagga agctctgccc tgcccacccc tcctctcctt
     2641 acagctggac gtcatccgga tccagctctc ttagacagtt aatcctaagt ttgactatcc
     2701 tatatctctc ttcctcttca cttctcccct ggtaaatgtt tcaaccttct gtgctggtcg
     2761 ctgtggcaaa cgacctttga ctatgctgta gtgatggcga tgccaaactc cctgctgttt
     2821 ctggtccttt aagccacaaa gtgacttaca aagccaggca gaacagaaat gcagctacat
     2881 atcttgagtc ccaaagatta cctagaatca attgtcacag agaaaaaagg aagatgaagg
     2941 tgttatgcca actactaccc tactgaacac tgcgactcct gggtgcctgt caggtgtgtg
     3001 tggatattgc tgcctcttaa attagctagc aatattatta aattggttca ttttataaat
     3061 agtttctatt ttttgtaaca ttactcagat atgtatcctg ggctcaaagg tgtatttcca
     3121 tagtatacca tcactagtac ttctgagctc aaaactcaac atcatgggaa agtttgtaaa
     3181 attgaatagt gtgtctatgt ctagatcatg agccattttt aacatcacac aaaacttgtg
     3241 tgtttgtgtg catgtgtgtg tgtaaaagca aaaaccggct caggttatca taggcaggta
     3301 tatttaatta gagaatacgt aacgctggag cagagaaatg tcagagtggc caccgcagag
     3361 gcagtatgaa gcatcgacgg tcaaatgagt tcagaggtgc tgcacgcttt gattgttcct
     3421 gagagattga cactgtgcac tggtaaactg tctgaaagct ctgacaataa agatgctggc
     3481 ttaagctcag tgtaaattca
//
