LOCUS       NM_009951               8382 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Mus musculus insulin-like growth factor 2 mRNA binding protein 1
            (Igf2bp1), transcript variant 1, mRNA.
ACCESSION   NM_009951 NM_176983
VERSION     NM_009951.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8382)
  AUTHORS   Wang,S., Ma,Y., Li,W., Zhao,Y., Gao,Y. and Wang,S.
  TITLE     LncRNA SNHG5/IGF2BP1/Occludin axis regulates Nd2O3 induced
            blood-testis barrier disruption
  JOURNAL   Environ Pollut 358, 124527 (2024)
   PUBMED   38992831
  REMARK    GeneRIF: LncRNA SNHG5/IGF2BP1/Occludin axis regulates Nd2O3 induced
            blood-testis barrier disruption.
REFERENCE   2  (bases 1 to 8382)
  AUTHORS   Han,Y., Sun,K., Yu,S., Qin,Y., Zhang,Z., Luo,J., Hu,H., Dai,L.,
            Cui,M., Jiang,C., Liu,F., Huang,Y., Gao,P., Chen,X., Xin,T.,
            Ren,X., Wu,X., Song,J., Wang,Q., Tang,Z., Chen,J., Zhang,H.,
            Zhang,X., Liu,M. and Luo,D.
  TITLE     A Mettl16/m6A/mybl2b/Igf2bp1 axis ensures cell cycle progression of
            embryonic hematopoietic stem and progenitor cells
  JOURNAL   EMBO J 43 (10), 1990-2014 (2024)
   PUBMED   38605226
  REMARK    GeneRIF: A Mettl16/m[6]A/mybl2b/Igf2bp1 axis ensures cell cycle
            progression of embryonic hematopoietic stem and progenitor cells.
REFERENCE   3  (bases 1 to 8382)
  AUTHORS   Wang,J., Guo,X., Chen,Y., Zhang,W., Ren,J. and Gao,A.
  TITLE     The m6A reader IGF2BP1 attenuates the stability of RPL36 and cell
            proliferation to mediate benzene hematotoxicity by recognizing m6A
            modification
  JOURNAL   Toxicology 503, 153758 (2024)
   PUBMED   38367942
  REMARK    GeneRIF: The m6A reader IGF2BP1 attenuates the stability of RPL36
            and cell proliferation to mediate benzene hematotoxicity by
            recognizing m6A modification.
REFERENCE   4  (bases 1 to 8382)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   5  (bases 1 to 8382)
  AUTHORS   Parham,L.R., Williams,P.A., Katada,K., Nettleford,S.K.,
            Chatterji,P., Acheampong,K.K., Danan,C.H., Ma,X., Simon,L.A.,
            Naughton,K.E., Mizuno,R., Karakasheva,T., McMillan,E.A.,
            Whelan,K.A., Brady,D.C., Shaffer,S.M. and Hamilton,K.E.
  TITLE     IGF2BP1/IMP1 Deletion Enhances a Facultative Stem Cell State via
            Regulation of MAP1LC3B
  JOURNAL   Cell Mol Gastroenterol Hepatol 17 (3), 439-451 (2024)
   PUBMED   38081361
  REMARK    GeneRIF: IGF2BP1/IMP1 Deletion Enhances a Facultative Stem Cell
            State via Regulation of MAP1LC3B.
REFERENCE   6  (bases 1 to 8382)
  AUTHORS   Leeds,P., Kren,B.T., Boylan,J.M., Betz,N.A., Steer,C.J.,
            Gruppuso,P.A. and Ross,J.
  TITLE     Developmental regulation of CRD-BP, an RNA-binding protein that
            stabilizes c-myc mRNA in vitro
  JOURNAL   Oncogene 14 (11), 1279-1286 (1997)
   PUBMED   9178888
REFERENCE   7  (bases 1 to 8382)
  AUTHORS   Prokipcak,R.D., Herrick,D.J. and Ross,J.
  TITLE     Purification and properties of a protein that binds to the
            C-terminal coding region of human c-myc mRNA
  JOURNAL   J Biol Chem 269 (12), 9261-9269 (1994)
   PUBMED   8132663
REFERENCE   8  (bases 1 to 8382)
  AUTHORS   Herrick,D.J. and Ross,J.
  TITLE     The half-life of c-myc mRNA in growing and serum-stimulated cells:
            influence of the coding and 3' untranslated regions and role of
            ribosome translocation
  JOURNAL   Mol Cell Biol 14 (3), 2119-2128 (1994)
   PUBMED   8114742
REFERENCE   9  (bases 1 to 8382)
  AUTHORS   Forejt,J. and Gregorova,S.
  TITLE     Genetic analysis of genomic imprinting: an Imprintor-1 gene
            controls inactivation of the paternal copy of the mouse Tme locus
  JOURNAL   Cell 70 (3), 443-450 (1992)
   PUBMED   1322799
REFERENCE   10 (bases 1 to 8382)
  AUTHORS   Bernstein,P.L., Herrick,D.J., Prokipcak,R.D. and Ross,J.
  TITLE     Control of c-myc mRNA half-life in vitro by a protein capable of
            binding to a coding region stability determinant
  JOURNAL   Genes Dev 6 (4), 642-654 (1992)
   PUBMED   1559612
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL603682.36 and AL606704.20.
            
            On Mar 1, 2008 this sequence version replaced NM_009951.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK013940.1, AK044850.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164142 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-486               AL603682.36        29739-30224         c
            487-547             AL603682.36        28503-28563         c
            548-596             AL603682.36        3901-3949           c
            597-648             AL603682.36        3562-3613           c
            649-712             AL606704.20        68649-68712         c
            713-994             AL606704.20        67328-67609         c
            995-1129            AL606704.20        66434-66568         c
            1130-1252           AL606704.20        64058-64180         c
            1253-1388           AL606704.20        63238-63373         c
            1389-1511           AL606704.20        62188-62310         c
            1512-1631           AL606704.20        61752-61871         c
            1632-1706           AL606704.20        60938-61012         c
            1707-1838           AL606704.20        60040-60171         c
            1839-1952           AL606704.20        59566-59679         c
            1953-8382           AL606704.20        50552-56981         c
FEATURES             Location/Qualifiers
     source          1..8382
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 59.08 cM"
     gene            1..8382
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /note="insulin-like growth factor 2 mRNA binding protein
                     1"
                     /db_xref="GeneID:140486"
                     /db_xref="MGI:MGI:1890357"
     exon            1..486
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /inference="alignment:Splign:2.1.0"
     CDS             312..2045
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     coding region determinant binding protein; zipcode binding
                     protein 1; VICKZ family member 1; IGF2 mRNA-binding
                     protein 1; IGF-II mRNA-binding protein 1; insulin-like
                     growth factor 2, binding protein 1; insulin-like growth
                     factor 2 mRNA binding protein 1 dN CRDBP-2; insulin-like
                     growth factor 2 mRNA binding protein 1 deltaN CRDBP"
                     /codon_start=1
                     /product="insulin-like growth factor 2 mRNA-binding
                     protein 1 isoform 1"
                     /protein_id="NP_034081.1"
                     /db_xref="CCDS:CCDS25286.1"
                     /db_xref="GeneID:140486"
                     /db_xref="MGI:MGI:1890357"
                     /translation="MNKLYIGNLNESVTPADLEKVFAEHKISYSGQFLVKSGYAFVDC
                     PDEHWAMKAIETFSGKVELQGKRLEIEHSVPKKQRSRKIQIRNIPPQLRWEVLDSLLA
                     QYGTVENCEQVNTESETAVVNVTYSNREQTRQAIMKLNGHQLENHALKVSYIPDEQIT
                     QGPENGRRGGFGSRGQPRQGSPVAAGAPAKQQPVDIPLRLLVPTQYVGAIIGKEGATI
                     RNITKQTQSKIDVHRKENAGAAEKAISVHSTPEGCSSACKMILEIMHKEAKDTKTADE
                     VPLKILAHNNFVGRLIGKEGRNLKKVEQDTETKITISSLQDLTLYNPERTITVKGAIE
                     NCCRAEQEIMKKVREAYENDVAAMSLQSHLIPGLNLAAVGLFPASSSAVPPPPSSVTG
                     AAPYSSFMQAPEQEMVQVFIPAQAVGAIIGKKGQHIKQLSRFASASIKIAPPETPDSK
                     VRMVVITGPPEAQFKAQGRIYGKLKEENFFGPKEEVKLETHIRVPASAAGRVIGKGGK
                     TVNELQNLTAAEVVVPRDQTPDENDQVIVKIIGHFYASQMAQRKIRDILAQVKQQHQK
                     GQSNLAQARRK"
     exon            487..547
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            548..596
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            597..648
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            649..712
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            713..994
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            995..1129
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..1252
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1253..1388
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1389..1511
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1512..1631
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1632..1706
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1707..1838
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1839..1952
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /inference="alignment:Splign:2.1.0"
     exon            1953..8382
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      7914..7919
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /note="hexamer: AATAAA"
     polyA_site      7934
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
     regulatory      8359..8364
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /note="hexamer: AATAAA"
     polyA_site      8382
                     /gene="Igf2bp1"
                     /gene_synonym="CRD-BP; Crdbp; D030026A21Rik; D11Moh40e;
                     D11Moh45; IMP1; mir-3063; Neilsen; ZBP-1; Zbp1"
                     /note="major polyA site"
ORIGIN      
        1 ggagaaacgt gacacaccag cccgctcgca ggggtttcgg accgaaggga aggagccgcg
       61 ccgcgtcgtc gtcagcctcc cctgcactcg gcgggcactt ctcccgggct cacccaaact
      121 ctcccgtgac ccccgcgtgc cctcaggccg cccacccgcc cggagctccg gacaacttca
      181 ggggtggggt gcgtagaaag tttgcggctc ccgccgcccg tctccacgcc tctcggccta
      241 ggaggctctc cgcccgcgcc cgcccggctc ggccttgcct ggaaccgtgt ccttgccccg
      301 ccaccgccac catgaacaag ctttacatcg gcaacctcaa cgagagtgtg acccccgcag
      361 acttggagaa agtattcgcg gagcacaaga tctcctacag cggccagttc ttggtcaaat
      421 ccggctacgc cttcgtggat tgccccgacg agcactgggc gatgaaggcc atcgaaactt
      481 tctcggggaa agtagaactg caaggaaaac gtctagagat tgaacactca gtccccaaaa
      541 aacaaaggag tcggaaaata cagatccgca atattccacc tcagctccga tgggaagtgc
      601 tagatagcct gctggctcag tacggtacag tggagaactg tgagcaagtg aacactgaaa
      661 gtgagacagc tgtggtcaac gtcacctact ctaaccggga gcagaccagg caagctatca
      721 tgaagctaaa tggccatcaa ctggagaacc atgccctgaa ggtctcctac atacctgatg
      781 agcagataac gcaaggtcct gagaatgggc gtcgtggagg ctttgggtct cggggccagc
      841 cccggcaagg gtcgcccgtg gcagcagggg ctccagccaa gcagcagcca gtggacatcc
      901 ctctccggct cctggtgcct acgcagtatg taggcgctat cattggcaag gagggtgcca
      961 ccatccgaaa catcacaaaa cagacgcagt ccaaaataga cgtgcatagg aaggagaatg
     1021 cgggcgctgc ggagaaggcc atcagcgtgc attcaacccc tgaaggctgc tcctccgcgt
     1081 gcaagatgat cttggagatt atgcacaagg aggcaaagga caccaaaacg gcagatgaag
     1141 ttcccctgaa gatcctggct cataacaact tcgtcgggcg actcattggc aaggaagggc
     1201 ggaacctgaa gaaggtggag caggacacag agacgaagat caccatctca tcgctccagg
     1261 acctcacgct ctataaccct gagaggacca tcactgtgaa gggcgccatt gagaactgtt
     1321 gcagggccga gcaggagatc atgaagaaag ttcgagaggc ttacgagaac gacgtggccg
     1381 ccatgagctt gcagtcccac ctcatccctg ggcttaacct ggctgctgta ggtctcttcc
     1441 cagcttcatc cagcgctgtc cctcctcctc ccagcagtgt caccggggct gctccctata
     1501 gctccttcat gcaggctccg gagcaggaga tggtacaagt gttcatcccc gcccaggctg
     1561 tgggcgccat cattggcaag aagggccagc acatcaaaca actctcccgc ttcgccagcg
     1621 cctccatcaa gattgcacca ccagaaacac ctgactccaa agttcgaatg gtcgtcatca
     1681 ctggaccccc agaggctcag ttcaaggccc agggaagaat ctatggcaaa ctaaaagaag
     1741 agaatttctt tggtcccaag gaggaagtaa agctagagac ccacatacgg gttccggctt
     1801 cagcagccgg ccgtgtcatc ggcaaaggcg gcaaaacggt gaatgagctg cagaacttga
     1861 ccgcagctga ggtggtagtg ccaagagacc agaccccgga tgagaacgac caagtcattg
     1921 ttaagatcat cggacatttc tatgccagcc agatggctca gcggaagatc cgagacatcc
     1981 tggctcaagt taagcaacag caccagaagg gacagagcaa cctggcccag gctcggagga
     2041 agtgaccccg ccccctcctg tcccattggc tccaagatca gcaggaggaa cacagaactg
     2101 gaggggcggg tggagggccg gtgtgctctt cccagcaggc ctgagaatga gtgggaatca
     2161 gggcatttgg gcctggctgg agatcaggtt tgcacactgt cttgagaaca atgttccagt
     2221 gaggaatcct gatctctcgc ccccaattga gccagctggc cacagcccac cccttggaat
     2281 atcaccattg caatcatagc ttgggttgct tttaaacgtg gattgtcttg aagttctcca
     2341 gcctccatgg aaggatgggt cagatcccag tggggaagag aaataaaatt tccttcaggt
     2401 tttataaaac ctcaaaggat ggtttgtttc ttaacccctc caaatctttc taaccttctt
     2461 ggttaattca cgaaaattcc tcccgttctt aatgtcctga ccagtaactt acctcttcct
     2521 ggatccattc acactgtttc agccttgttg tgctggggtg ggggaggggc gggaggaggg
     2581 ctagaacaca gctttgttta caatattaac tctggagagc cctatcctgg atagtctaat
     2641 tctgattttt ccttaaccaa ccattaggaa cagcaagata taaaggagag agttaataat
     2701 tacagtatgt accgatccac gtttaaaagg agtccttggg ctaaggatag agctcgccgg
     2761 gcacagtgct tgcccggcac ggacgaggcc ctggcttcta tccttggcat cacaaaaaga
     2821 aaaagaaaaa aaaaagcatg ccttatggct gagctcttgc agatcttgaa aaattggcac
     2881 agcagaaatt cctcctggcc ggccagctgg ggcttcccca cctcacttat gcccctgtaa
     2941 ccctgggagt cctgcacggt gccctggtac aggggagtgg tgctgcgtgc ttcagggtag
     3001 ggctgaccac ggtccctgat tcccaccatt ctctctcagg cggattttat atatttttta
     3061 aagtctattt taatgatggg atatatgagc tctgggaagg gggtgtgagc tccctttggt
     3121 aaagtctcgg ttctgtggag gagttgagtg gcccaaaggt gctctcgctc cacccgcgtg
     3181 ctttgacaag ggctgaggca gctgttgcgg tgtgtgtgtc cccaccacgg cactgttccc
     3241 ttgtggtggt cggactacaa cccaaccctg agctcctgat aaagcttaaa atttagtcca
     3301 tcatctggca aacttagtaa attggagaat gtcgcttctg tttttatcta gaggagtatt
     3361 taactgactg cttatgcctc cgtgaatgtc attgttatta tgaaaggtgt gcctgaaaac
     3421 aaaccagagt accagccgca ttatgcacag aggggtgagc acacttaatt tattaattta
     3481 ccaggctcac tgagatcctg ttggaagtta acccttgtgg agggcagcgg ccatcagtta
     3541 agtgaggctc agcctccctc ccgatcctgt actgactgta atgcatatta gccaggtgat
     3601 gcactttagc taccctggac aatgctgtca agtgtgctgg gaagaaagga aggcctctct
     3661 gcctgtgctc ggggtccccg cttcctgata ttgcaaggac aacagtgaca aagctaccgt
     3721 gacgtgtggg cggagtcagg cagtgctgtg cgaagtaaac tacctcaagg tgtgaagtta
     3781 cctcagcaat ggttttcctt ttgttcccta aatcctggtt tttaattttc tttctttttt
     3841 ttaatttttt tttttttttt tttgcggctt gctgatattt tatataaaaa aaaagaaaag
     3901 cgaagcaaaa gagaagctga tagtcttgaa tattttattt ttttaatgaa aagaaaaaat
     3961 gagaaagtta tgtttcataa tttcttaaaa catgagccag taactctttt ggggctctgt
     4021 ggagaaaagg ccctgtgggg gaaaggtggg ggttggggcc tggatccagg ggaggaggcc
     4081 atggtgaagt ggaaaactcc aaggagccca ggtcctccct gggttctaga ctctgacctt
     4141 gaagtaggat ttaagatcta gcagagcttt agcccttggg ggtcaaactg tgggcacccc
     4201 tcctcccctc tggtgagaca gtaccttagc cggctcttcc caccagcggt gctgttattt
     4261 tatgatattg cctccgtttt atcgaggaaa gaaataataa ctaaaaaata atactgtttt
     4321 aaaagaaacc tgtatttctt taaaaatatg ggagccaaga ctccgtttat gggaaagaca
     4381 aggccactct gttcccatcg ggccacctgg tttgtcatta cagtgctttt cctgatgatt
     4441 ttttggttat tgtttcattc ccaccccacc ttgttcttgt ctgtgtcatt ctgcatagac
     4501 cacaaggcca gcggaccctc cataactgcc ctccccgtct ccctgcctcc ttaggttgat
     4561 ctgcttcatt ctaaaagtgg acctgttagg gcattcttgg ttttagagtg gtgggtagcc
     4621 aagaggagga agaggaaatg ctgagtgtgg ttgggacagg gtcttaccac ttggtcccca
     4681 tcacagccac ggtctctcat aggctccaga ccatttagtc caaagagaga aacagtcttt
     4741 aggatgtaac aggccagtag aattaagctt cccacctggc tctatgtgct ttgttcccat
     4801 tcaaagcaga caatgttcag acatcggcca tttagtgatt tcaagtggat ttcttgcagc
     4861 aagcatgctt tgatacctgg ttcaagtgac catgggggga tcccatagta cctggaatga
     4921 gattgctgga gcgtctgttc cttggggacc tgcccccttc acaccttaag tccaagtcct
     4981 tccctttagc tgattgagct cccagaagag atcagaacat gtgtgacaag ggacctgaaa
     5041 acttacatgg actaggcaag gttccactca tggctggatt tgcccagcag caagattgtg
     5101 aaagttggct tcctaatgaa agtaagaata tggactaggg gcagaggtca gcaggaaggg
     5161 agagcctggc ttatttgggt tgtctggtga ctcaaaggcc agatcttagg gcagctcctt
     5221 accctgcttg tcacctcttt tttttttttt ttccaaaccc tgtcctaggt aagatggcaa
     5281 attattacaa aaagcacttg ggatatttgg acagttgaga aaagcaacct ttagaagaaa
     5341 ctgcttctgt gctcagaggt ctatgtatag aggtgtgtgt gtgtgcacta cacacgtagt
     5401 tttatgaatg aaaggatcat ctcttgggtc tattttttaa attcttggaa acacataaaa
     5461 agccaaatgg tttgactcac tgactgactt tgaagctgca tctgccgctt acaccgcagt
     5521 ggctttaacc ccctctgggg tctggttgcc ttttgcagtt tgtggactta gttgctggaa
     5581 ggaggtctag gtacgaggga agtcgtgtgg cctttgactc tttccggtcc tttctgtctt
     5641 tcatttccct aaactctccg cttttgggga aaactcctgc ctcgctattg gctggagaca
     5701 ccatgtcaaa accccgagga tgctgggaca ggatgttcca gttggttctg tatgtccgtt
     5761 ttcctttgtg ccaaagacag acagacagac agaggctgag aggctgtttc taagacaaag
     5821 cagtggccgg ccatctttct acatctccta ggcctgtctg tgagggggag ggtcctggag
     5881 actacactaa agacaagcac cactcttgtt aagttcctgg gggattgggg tgtggtgctt
     5941 gcccagggct agggagcagg gaaaaggggg tcctgttgca ctttggggaa ggagggactc
     6001 ttgggctccc tgtgggactg ctctcctccc ctgtccccac tgcagagatg gcaccgtgga
     6061 gttcccttca ggcctggcag actggcagtg aggaggggcc tcagttagct ctcaagggtg
     6121 ccttcccctc ctcccttccc agacaccctc tgccaaactg ggaaccagca gtgctattaa
     6181 ctacctcagc cccagagggc gccaagccta actgagcccc aggaggagct gtcgatttag
     6241 gcaactcttc tccccctctc tcgggacgag gtcgcctttc cttgtcctaa gtgctcctgg
     6301 gggagatcct agtggctttg ccattcagac cacacaactg tttttgcctg tttgttgaaa
     6361 accaatagaa ggagaccagc ttggcaggac attgcaggaa gagaccccct catcaatgcc
     6421 aggggatgta aaagccattt tccttccaga tactcaatgg tttaggtgca gaatgttgtt
     6481 cttgtattca gacatacata gagtaatacc agctgaaaca tggtgtttct ttcctttgga
     6541 tacatctcag tgagggttca agatccggga caggccacat gcttcatggt ctagaggcta
     6601 ggccaaagcc tcaaccctgc acggcctgat gtggtatcat tacggatgcc ctcaaatggg
     6661 tgactatgga ctgacaaaag aagagaattt gtttttctta aatagcagga tgctcctgga
     6721 gcgtgtgttt ttcataatca cagatgatga atactacgag tataaatgga tgaactacct
     6781 cagtcctcac agtaagattg gagatgaggg cagggactca tgcctcgggg atgaatccca
     6841 gccaggagag agttttggct tatgccacac taggtttgtc atggggatcg ggcaggcttg
     6901 cccgggtccc cactcacatt ggtcgggttg gcagggttcc gtcatctcgt gtcccctccc
     6961 ccccacccca tccccttttc tgctctcctc ccccactctc tcatcccttc actccagctc
     7021 ctccccctct ctctcagagc ttaagcttaa gcttgatgtg aggaaaggaa tgggctcctt
     7081 ccctagagag ctggatggag ggtggttctg ggtccggcct ggaatcccct agtcagctcc
     7141 taacttggga accggggcct cttcaacagg gtttcttcaa gatcctctgc ctccactgag
     7201 tcccctcggg aggtgtgtgt gtgtatgggg ggagggggcg cgctctgaga tagagcagga
     7261 tccttctgcc ctggggcctg gtccagtcta ccaggctcgc tcaggccacc tttgtagttg
     7321 accaccgcca ggtgccctag ccctccccac ccctaaatga cctccttata gaagcctgtt
     7381 tcacttttgg ttttaatcta cctcttagca aaacaatata gagaaattta ggtagtggca
     7441 actccacttg cttaggttag gcgggggaaa gatttctttt tccaaaggaa aaactattac
     7501 cttaaaaata ctttccaaaa aatcttaaaa aaaaaaaaaa taaaaaccaa aaaaaatttt
     7561 tttttctttt aagggaggga gacaatttcc agtaaccatg ggattaattt cctacactct
     7621 tttcccccat acatatggtt tcctctttgg cagttgtcac atgtcacgta atgatacggc
     7681 tttcccagtg atctccttgt ctggtcacat ccccacccca aggagtgcca gtgagactca
     7741 cctgtgcttc ctgtcacagc tctggccagg tgacctggac atctcaaaca ggagcactgg
     7801 gcaggggtgc ttctggactc gttagggaac ctcatgtgac cacagtttta tgtgaaccac
     7861 tgcttataag ctcattggaa atgaatttaa gcagattata aatttgcatg atgaataaat
     7921 accttttacc accatttgga gtctcccttc tcttcagaaa tcgtgattct gttctccgaa
     7981 accagagttg aatgagaaga gcccactctg gcagaatggg ttgataggca gtccgaggac
     8041 acggcttccg gggagggctt tatttttctg agtggatgtc tgggaggcat tggggggctg
     8101 ctgcttgtga ctgttagact ctgtaattgc gataactttg ggattgtatt ttaccagaac
     8161 tctgccggcc atcctgaccc tgaatttgat tgtgccttcc tccctccctt ctctgttctt
     8221 gaagctgggg gaggggcagc gggctcggac ttggctagtt tgtttattga atggatgaac
     8281 gaacactccc gggggtccct tccgggggaa agctgtttca gccacaaagc aatctcattc
     8341 cactgttttc agcctcaaaa taaaaggaaa cttatattga aa
//
