LOCUS       NM_001290315            6253 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus immunoglobulin superfamily, DCC subclass, member 4
            (Igdcc4), transcript variant 1, mRNA.
ACCESSION   NM_001290315 XM_006511312
VERSION     NM_001290315.2
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6253)
  AUTHORS   Comerford,S.A., Hinnant,E.A., Chen,Y. and Hammer,R.E.
  TITLE     Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed
            bile duct development and loss of hepatocyte viability; a
            ribosomopathy-like phenotype that is partially p53-dependent
  JOURNAL   PLoS Genet 19 (1), e1010595 (2023)
   PUBMED   36656901
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6253)
  AUTHORS   Kutting,F., Gebauer,F., Zweerink,S., Kramer,L., Schramm,C.,
            Quaas,A., Bruns,C., Goeser,T. and Nierhoff,D.
  TITLE     Expression of Neighbor of Punc E11 (NOPE) in early stage esophageal
            adenocarcinoma is associated with reduced survival
  JOURNAL   Sci Rep 12 (1), 3584 (2022)
   PUBMED   35246597
  REMARK    GeneRIF: Expression of Neighbor of Punc E11 (NOPE) in early stage
            esophageal adenocarcinoma is associated with reduced survival.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6253)
  AUTHORS   Song,Y., Huang,H., Hu,Y., Zhang,J., Li,F., Yin,X., Shi,J., Li,Y.,
            Li,C., Zhao,D. and Chen,H.
  TITLE     A genome-wide CRISPR/Cas9 gene knockout screen identifies
            immunoglobulin superfamily DCC subclass member 4 as a key host
            factor that promotes influenza virus endocytosis
  JOURNAL   PLoS Pathog 17 (12), e1010141 (2021)
   PUBMED   34871331
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6253)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6253)
  AUTHORS   Xiang,C., Frietze,K.K., Bi,Y., Li,Y., Dal Pozzo,V., Pal,S.,
            Alexander,N., Baubet,V., D'Acunto,V., Mason,C.E., Davuluri,R.V. and
            Dahmane,N.
  TITLE     RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell
            Identity and Glioblastoma Subtypes in Developing Neurons
  JOURNAL   Mol Cell Biol 41 (7), e0052620 (2021)
   PUBMED   33903225
REFERENCE   6  (bases 1 to 6253)
  AUTHORS   Marquardt,J.U., Quasdorff,M., Varnholt,H., Curth,H.M.,
            Mesghenna,S., Protzer,U., Goeser,T. and Nierhoff,D.
  TITLE     Neighbor of Punc E11, a novel oncofetal marker for hepatocellular
            carcinoma
  JOURNAL   Int J Cancer 128 (10), 2353-2363 (2011)
   PUBMED   20658536
  REMARK    GeneRIF: identified Nope as a novel oncofetal surface marker for
            murine and human HCC. Nope is specifically expressed by epithelial
            tumor cells but not in preneoplastic stages and is a promising
            marker
REFERENCE   7  (bases 1 to 6253)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Aizawa,H., Yuasa,S.,
            Nakajima,D., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: II. The complete nucleotide sequences of 400 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (1), 35-48 (2003)
   PUBMED   12693553
REFERENCE   8  (bases 1 to 6253)
  AUTHORS   Salbaum,J.M. and Kappen,C.
  TITLE     Cloning and expression of nope, a new mouse gene of the
            immunoglobulin superfamily related to guidance receptors
  JOURNAL   Genomics 64 (1), 15-23 (2000)
   PUBMED   10708514
REFERENCE   9  (bases 1 to 6253)
  AUTHORS   Salbaum,J.M.
  TITLE     Genomic structure and chromosomal localization of the mouse gene
            Punc
  JOURNAL   Mamm Genome 10 (2), 107-111 (1999)
   PUBMED   9922388
REFERENCE   10 (bases 1 to 6253)
  AUTHORS   Stewart,G.J., Savioz,A. and Davies,R.W.
  TITLE     Sequence analysis of 497 mouse brain ESTs expressed in the
            substantia nigra
  JOURNAL   Genomics 39 (2), 147-153 (1997)
   PUBMED   9027501
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC122463.4 and AC161366.6.
            
            On Dec 23, 2022 this sequence version replaced NM_001290315.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note:.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB052621.1, SRR10223970.11391.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-140               AC122463.4         156542-156681
            141-494             AC161366.6         46879-47232         c
            495-636             AC161366.6         46050-46191         c
            637-773             AC161366.6         40137-40273         c
            774-914             AC161366.6         38571-38711         c
            915-1070            AC161366.6         37685-37840         c
            1071-1484           AC161366.6         36302-36715         c
            1485-1649           AC161366.6         35715-35879         c
            1650-1787           AC161366.6         35069-35206         c
            1788-1961           AC161366.6         33563-33736         c
            1962-2198           AC161366.6         31787-32023         c
            2199-2300           AC161366.6         31610-31711         c
            2301-2484           AC161366.6         29745-29928         c
            2485-2612           AC161366.6         29020-29147         c
            2613-2783           AC161366.6         28712-28882         c
            2784-2921           AC161366.6         28428-28565         c
            2922-3027           AC161366.6         27335-27440         c
            3028-3256           AC161366.6         26623-26851         c
            3257-3421           AC161366.6         25854-26018         c
            3422-6253           AC161366.6         22548-25379         c
FEATURES             Location/Qualifiers
     source          1..6253
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 35.1 cM"
     gene            1..6253
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /note="immunoglobulin superfamily, DCC subclass, member 4"
                     /db_xref="GeneID:56741"
                     /db_xref="MGI:MGI:1858497"
     exon            1..140
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..3838
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; neighbor of Punc e11 protein; amplimer
                     WI-16786, mouse homolog; amplimer WI-18508, mouse homolog"
                     /codon_start=1
                     /product="immunoglobulin superfamily DCC subclass member 4
                     isoform 1 precursor"
                     /protein_id="NP_001277244.1"
                     /db_xref="CCDS:CCDS72258.1"
                     /db_xref="GeneID:56741"
                     /db_xref="MGI:MGI:1858497"
                     /translation="MARADTGRGLLVLTFCLLSARGELPLPQETTVKLSCDEGPLQVI
                     LGPEQAVVLDCTLGATAAGPPTRVTWSKDGDTVLEHENLHLLPNGSLWLSSPLEQEDS
                     DDEEALRIWKVTEGSYSCLAHSPLGVVASQVAVVKLATLEDFSLHPESQIVEENGTAR
                     FECHTKGLPAPIITWEKDQVTVPEESRLITLPNGVLQILDVQDSDAGSYRCVATNSAR
                     QRFSQEASLTVALRGSLEATRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSW
                     VRQDGKPISTDVIVLGRTNLLIASAQPRHSGVYVCRANKPRTRDFATAAAELRVLAAP
                     AISQAPEALSRTRASTARFVCRASGEPRPALHWLHDGIPLRPNGRVKVQGGGGSLVIT
                     QIGLQDAGYYQCVAENSAGTACAAAPLAVVVREGLPSAPTRVTATPLSSSSVLVAWER
                     PELHSEQIIGFSLHYQKARGVDNVEYQFAVNNDTTELQVRDLEPNTDYEFYVVAYSQL
                     GASRTSSPALVHTLDDVPSAAPQLTLSSPNPSDIRVAWLPLPSSLSNGQVLKYKIEYG
                     LGKEEDQVFSTEVPGNETQLTLNSLQPNKVYRVRISAGTGAGYGVPSQWMQHRTPGVH
                     NQSHVPFAPAELKVRAKMESLVVSWQPPPHPTQISGYKLYWREVGTEEEADGDRPPGG
                     RGDQAWDVGPVRLKKKVKQYELTQLVPGRLYEVKLVAFNKHEDGYAAVWKGKTEKAPT
                     PDLPIQRGPPLPPAHVHAESNSSTSIWLRWKKPDFTTVKIVNYTVRFGPWGLRNASLV
                     TYYTSSGEDILIGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRL
                     SPLTPSTVRLHWCPPTEPNGEIVEYLILYSNNHTQPEHQWTLLTTEGNIFSAEVHGLE
                     SDTRYFFKMGARTEVGPGPFSRLQDVITLQKTFSDSLDVHAVTGIIVGVCLGLLCLLA
                     CMCAGLRRSSHREALPGLSSSGTPGNPALYTRARLGPPSVPAAHELESLVHPRPQDWS
                     PPPSDVEDKAEVHSLMGGSVSDCRGHSKRKISWAQAGGPNWAGSWAGCELPQGSGPRP
                     ALTRALLPPAGTGQTLLLQALVYDAIKSNGRKKPSPACRNQVEAEVIVHSDFGASKGC
                     PDLHLQDLEPEEPLTAETLPSTSGAVDLSQGADWLGRELGGCQPTTSGPERLTCLPEA
                     ASASCSCSDLQPSTAIEEAPGKSCQPKALCPLTVSPSLPRAPVSSAQVP"
     exon            141..494
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            495..636
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            637..773
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            774..914
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1070
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            1071..1484
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            1485..1649
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            1650..1787
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            1788..1961
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            1962..2198
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            2199..2300
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            2301..2484
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            2485..2612
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            2613..2783
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            2784..2921
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            2922..3027
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            3028..3256
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            3257..3421
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     exon            3422..6253
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6234..6239
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /note="hexamer: AATAAA"
     polyA_site      6253
                     /gene="Igdcc4"
                     /gene_synonym="DDM36; Nope"
                     /note="major polyA site"
ORIGIN      
        1 actgacgccc ggcgcgccct cccccggcgg cggcccaggc gcccggacgc ggcggcagcg
       61 gcccgagccc ggccctatgg cgcgggcgga cacgggccgc gggctcctgg tgctgacctt
      121 ctgcctgctg tccgcgcgcg gggagctgcc attgccccag gagacaactg tcaagctgag
      181 ctgtgatgag ggacccctgc aagtgatcct gggccctgag caggctgtgg tgctggactg
      241 cactttgggg gctacagctg ctgggcctcc gaccagggtg acatggagca aggatggaga
      301 cactgtacta gagcatgaga acctgcacct gctacccaat ggctccctgt ggctgtcctc
      361 acccctagag caagaagaca gcgatgatga ggaagctctt aggatctgga aggtcactga
      421 gggcagctat tcctgtctgg cccacagccc gctaggagtg gtggccagcc aggttgctgt
      481 ggtcaagctt gccacactcg aagacttctc tctgcacccc gagtcccaga ttgtggagga
      541 gaacgggaca gcacgctttg aatgccacac caagggcctt ccagccccca tcattacttg
      601 ggaaaaggac caggtgaccg tgcctgagga gtcccggctc atcactcttc ccaatggcgt
      661 cctccagatc ctagatgtcc aggacagtga tgcaggctcc taccgctgcg tggccaccaa
      721 ttcagcccgc caacgattca gccaggaggc ctcgctcact gtggccctca gagggtcttt
      781 ggaggctacc agggggcagg atgtggtcat tgtggcagcc ccagagaaca ccacggtagt
      841 gtctggacag agtgtagtga tggagtgcgt ggcctctgct gaccccaccc cttttgtgtc
      901 ctgggtccga caggatggaa agcctatctc cacggatgtc atcgttctgg gccggaccaa
      961 tctactcatc gccagcgcgc agcctcggca ctctggagtc tatgtctgcc gagccaacaa
     1021 gccccgcacg cgtgatttcg ccactgcggc tgctgagctc cgagtgcttg ctgccccagc
     1081 catctcgcag gcgcccgagg cgctctcgcg gacgcgggcc agcaccgcgc gcttcgtgtg
     1141 ccgggcgtcc ggggagccac ggcccgcgct gcactggctg cacgacggga tcccgttgcg
     1201 acccaatggg cgcgtcaagg tgcagggcgg tggcggcagc ttggtcatca ctcagatcgg
     1261 ccttcaggac gctggctact accagtgcgt agcagaaaac agcgcgggaa ctgcctgtgc
     1321 cgctgcgccc ctggcggtag tggtgcgcga ggggctgccc agcgccccga ctcgggtcac
     1381 agccacgccg ctgagcagct cctctgtgct ggtggcctgg gagcggcctg agttgcacag
     1441 cgagcaaatc attggcttct ctcttcacta ccaaaaggca aggggagtgg acaatgtgga
     1501 gtaccagttt gcagtaaaca atgacaccac agagctgcag gttcgggacc tggaacccaa
     1561 cacggattat gagttctacg tggtggccta ctcccagctg ggggccagcc gaacctccag
     1621 cccagccctg gtgcatacac tggacgatgt ccccagcgca gcaccccagc ttaccttgtc
     1681 cagccccaac ccctcggaca tcagggtggc atggctgccc ctgccctcca gcctgagcaa
     1741 tggacaggtg ctgaagtaca agatagagta cggtttgggg aaggaagaag atcaggtttt
     1801 ctccaccgag gtgcctggaa atgagacaca acttacgtta aactcacttc agccaaacaa
     1861 agtgtaccga gtccggattt cagctggcac tggcgctggc tatggagtcc cttctcagtg
     1921 gatgcagcac aggacacctg gtgtgcacaa ccagagccat gttccctttg cccctgcaga
     1981 attgaaggtg agggcaaaga tggagtccct ggtggtgtca tggcagccgc cccctcaccc
     2041 cacccagatc tctggataca aactctactg gagagaggtg ggaacagagg aggaggcaga
     2101 tggtgaccgc cccccagggg gtcgtggaga tcaagcttgg gacgtcgggc ccgtgcggct
     2161 gaagaagaaa gtgaagcagt atgaactgac ccagttagtc cctggcaggc tgtacgaggt
     2221 gaagctcgta gctttcaaca aacacgagga cggctacgct gctgtgtgga agggcaagac
     2281 ggagaaggcg cccacgccag acctgcctat ccagaggggg ccaccgctgc ctcctgccca
     2341 tgtccacgca gagtcaaaca gctccacttc catttggctt cggtggaaga agccagactt
     2401 taccactgtc aagattgtca actacactgt acgcttcggc ccctgggggc tcaggaatgc
     2461 ttccctggtc acctactata ccagctctgg agaagacatt ctcattggcg gcctgaaacc
     2521 atttaccaag tacgagtttg cggtacagtc ccacggagtg gatatggatg ggccctttgg
     2581 ctccgtcgta gaacgctcca ccctgcctga ccggccttca acacctcctt ctgacctgcg
     2641 cctgagcccc ctgacaccat ccaccgttcg gttacactgg tgtcccccca cggagcccaa
     2701 tggtgagatt gtggagtatc taattctcta cagcaacaac cacacccagc ccgaacacca
     2761 gtggacactg ctcaccacag agggaaacat cttcagtgca gaggtccatg gcctagagag
     2821 tgacactcgg tatttcttca agatgggagc ccgcacagag gtggggcctg ggcccttttc
     2881 ccgcttgcag gatgtgatta ctctgcaaaa gacattctca gactccttgg atgtgcacgc
     2941 cgtcacgggc atcatcgtgg gtgtctgcct gggccttctc tgcctcctgg cctgcatgtg
     3001 tgctggccta cgacgaagct cccacaggga agccctgccc ggattgtcct cctcaggcac
     3061 cccaggaaac ccagcgctct acacaagagc tcgacttggg ccccccagtg tccctgctgc
     3121 ccatgagttg gagtccctcg tgcatcctcg tccccaggat tggtccccac caccctcaga
     3181 tgtggaagac aaggctgaag tacacagcct tatgggtggc agtgtttcag attgccgggg
     3241 ccactccaag agaaagatct cctgggctca ggcaggggga ccaaactggg caggctcctg
     3301 ggcaggctgt gagctgcccc agggtagtgg tccaaggccg gctctgaccc gtgctctgct
     3361 gcctccagcg ggaaccgggc agacactgct gctgcaagcc ctggtatatg acgccataaa
     3421 gagcaacggg agaaagaagc cgtccccagc ctgcaggaat caggtggaag ctgaggtcat
     3481 tgtccactcc gacttcggtg catccaaagg atgtcctgac ctccacctcc aagacctgga
     3541 gccagaggaa ccactgactg cagagactct gccttccacg tctggagctg tggatctgtc
     3601 tcaaggagca gactggctgg gcagggagct gggagggtgc caaccaacaa ccagtgggcc
     3661 agagaggctc acctgcttgc cagaagcagc cagtgcctcc tgctcctgct cagacctcca
     3721 gcccagcact gctatagagg aggcccctgg gaaaagctgc cagcccaaag ccctgtgtcc
     3781 tctaacagtc agcccaagcc ttcccagggc ccctgtctcc tctgctcagg tcccctgagc
     3841 agaaggcaga tatggctcag gaacatgcca tgcatggcta cacatgtgtg tactagagat
     3901 atccataagt ccttggagcc tcttagggtc ctttggctgg ggttggggag aactttactc
     3961 tccctcatat tctgcatcac atacaggagg gacttgagac acagctctgt gtaatggaca
     4021 cgtgtgaagt cgtgtgtgtg tgtgtgtgtg tgtgtgctgg ttgagctagg aaacctctcc
     4081 ctatgtagca ctcactgtgg cctagttgac cctccgtggc aggatggtgt aacagtgatc
     4141 agtgccagct ctttgagctt ttagccttgt cacctagcct tttattacac tctgagagtg
     4201 tctccagtgc tgtgtctaca aagacagcgc cagcccctct tctgtcagct gtgctgagca
     4261 gagtgccagt caactccacg ggcctatgac accgcagcct accacagcat ggctgtcatc
     4321 cccctggcct cctaaggtcc agatgtctgg gtgaacccag ctcagctccc ctctcctttg
     4381 agcatctctg tacctaattt tgtaatctgg gaagtgcctg gtttgggaaa tcttctttcg
     4441 caccctgtcc ctctctgccc cttccttcat ttgttctggt gatctgtctc atgtcatctt
     4501 gctcgattat cctggggccc ttctctttcc catgatgccc ctgatttcct cactgctgtt
     4561 ttcatttctg tctgccatgc ttgtctttat gtcgtgtgtt tctcgtccct gagttcaacc
     4621 tatgcaccct ttcctaacaa catgactacc tcatgtctgc ttcagaccat agtgtgaccc
     4681 ctgggtcccc acagctcccc tgccaaccgc cttcctgggc agatgaccca ctccaagtag
     4741 atctggaaaa gaccttgtgg cttgtctggc tgccctcccc ttggtgttga gatgagaagg
     4801 ttttctatgg aagagatgag tccaggctgc acaggggaac ccccaagaag gggtagggag
     4861 tgaaaccaag aggctgaaaa aaaatggctg ccacccatct gcacagagag atgggtgtgt
     4921 gcttttgacg tgcagtcctg gctgaaactg aaggggtgag gagaggggag ctactggggc
     4981 tgccatggct cagttccctg accctggagc cctgaacctg gcttcagagt agcaaagagt
     5041 ttcctccaag atgctgtaag ggaagtcttt gcataggaaa agggcggctg gctcatttta
     5101 ttttatcttt ctttacactg aatcccaaaa tcatcttacc acaaagggcc aagcctgact
     5161 ggtatttcct gagtcacaag agccatgcca tctctctggt ttctcacctc agtcatgtcc
     5221 cagaattgtc agatccagtg gcatctgtgc tcttgctgca catctttcta tttcaactgg
     5281 ctggcacatc aagtgttaac tctggcttct gggccaagtt agaaataacc agtctatttt
     5341 ccctttattt tattttattt tattttattt tatgtctttc agtggagttg tagcttctga
     5401 aagcgtctgt gtttattagc cttgtgtgtc actcatgttt gaccccaccc acatttcctt
     5461 ctcctcccct cttcagccag cctatgataa cactaaagat tattaatgct ggcttcgtat
     5521 ctcattaaag acaggattgt cacttgaact acttctatag cattcaaagt ggccacggcc
     5581 aacaccaccg tatgtttctt cattgctctg aaggtcaaga gcctcatttt gttttcctgg
     5641 ttagattttt ttcctccttg ccttgaatga aataaccgtt ttaacagtag gctcttagca
     5701 tcacaccaca tagtcattcc tcatgttctt gtttaacaag cactgaggtt ctggtttaaa
     5761 ttaaatagct gcaaatgaga caatttataa cccattaggc tgggtggaaa attgtttctc
     5821 aaaagcaaat aagtaataaa tctggtatct gcctataact cacagttgat aagaaagtag
     5881 ccagaactca ctagcattat atatgatttg ggttctgagt aactggggag tgttagcttt
     5941 gtgactttgt agcagcaggt cttattagga aagtctgttg gccttttaca gggcattagt
     6001 ccctttgtcg tttgccatgg atgccttaag ttctttggag tctcatttaa gaatttcttt
     6061 tctcgaagca tgacaagtgt atgcaatact tacatgctca ctcgtttacc tgtgcttagt
     6121 ttgtgctggg ttatttaatt gcactttcca gcatcatgct tcctccttac aaatatgata
     6181 ttctttattg ttacactaag gtgttgatca tgtatctgtc cctgtaaaga attaataaac
     6241 tattttccag aca
//
