LOCUS       NM_028235               2634 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus intraflagellar transport 70B (Ift70b), mRNA.
ACCESSION   NM_028235 XM_001002878 XM_001002885 XM_001003944 XM_485010
            XM_911984 XM_986297
VERSION     NM_028235.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2634)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2634)
  AUTHORS   Katoh,Y., Terada,M., Nishijima,Y., Takei,R., Nozaki,S., Hamada,H.
            and Nakayama,K.
  TITLE     Overall Architecture of the Intraflagellar Transport (IFT)-B
            Complex Containing Cluap1/IFT38 as an Essential Component of the
            IFT-B Peripheral Subcomplex
  JOURNAL   J Biol Chem 291 (21), 10962-10975 (2016)
   PUBMED   26980730
REFERENCE   3  (bases 1 to 2634)
  AUTHORS   Howard,P.W., Jue,S.F. and Maurer,R.A.
  TITLE     Interaction of mouse TTC30/DYF-1 with multiple intraflagellar
            transport complex B proteins and KIF17
  JOURNAL   Exp Cell Res 319 (14), 2275-2281 (2013)
   PUBMED   23810713
REFERENCE   4  (bases 1 to 2634)
  AUTHORS   Wei,Q., Zhang,Y., Li,Y., Zhang,Q., Ling,K. and Hu,J.
  TITLE     The BBSome controls IFT assembly and turnaround in cilia
  JOURNAL   Nat Cell Biol 14 (9), 950-957 (2012)
   PUBMED   22922713
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL773533.12 and BC026507.1.
            
            On or before Feb 18, 2007 this sequence version replaced
            XM_911984.2, XM_986297.1, XM_485010.3, XM_001003944.1,
            XM_001002885.1, XM_001002878.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-808               AL773533.12        131219-132026       c
            809-2634            BC026507.1         1-1826
FEATURES             Location/Qualifiers
     source          1..2634
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 44.79 cM"
     gene            1..2634
                     /gene="Ift70b"
                     /gene_synonym="2510042P03Rik; Tcc30b; Ttc30b"
                     /note="intraflagellar transport 70B"
                     /db_xref="GeneID:72421"
                     /db_xref="MGI:MGI:1919671"
     exon            1..2614
                     /gene="Ift70b"
                     /gene_synonym="2510042P03Rik; Tcc30b; Ttc30b"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..2050
                     /gene="Ift70b"
                     /gene_synonym="2510042P03Rik; Tcc30b; Ttc30b"
                     /note="tetratricopeptide repeat protein 30B; novel
                     tetratrico peptide repeat (TPR) containing protein; TPR
                     repeat protein 30B; tetratricopeptide repeat domain 30B"
                     /codon_start=1
                     /product="intraflagellar transport protein 70B"
                     /protein_id="NP_082511.1"
                     /db_xref="CCDS:CCDS38150.1"
                     /db_xref="GeneID:72421"
                     /db_xref="MGI:MGI:1919671"
                     /translation="MAGLSSSQIPDGEFTAVVYRLIRDSRYSEAVQLLSAELQRSSRS
                     RAGLSLLAYCYYRLQEFELAAECYEQLSQMHPELEQYRLYQAQALYKACLYPEATRVA
                     FLLDNPAYQTRVLRLQAAIKYSEGDLPGARSLVEQLLSGEGVEDSGGESDYDGQINLG
                     CLLYKEGHYEAACSKFLAALQASGYQPDLSYNLALAYYSSRQYAPALKHIADIIERGI
                     RQHPELGVGMTTEGIDVRSVGNTIVLHQTALVEAFNLKAAIEYQLRNYEAAQEALTDM
                     PPRAEEELDPVTLHNQALMNMDAKPTEGFEKLQFLLQQNPFPPETFGNLLLLYCKYEY
                     FDLAADVLAENAHLTYKFLTPYLYDFLDAMITCQTAPEEAFIKLDGLAGMLTEQLRKL
                     TIQVQDSRHSRDDESAKKAVNEYDETLEKYIPVLMAQAKIYWNFENYPMVEKIFRKSV
                     EFCNDHDVWKLNVAHVLFMQENKYKEAIGFYEPIVKKNYDNILSVSAIVLANLCVSYI
                     MTSQNEEAEELMRKIEKEEEQLSYGDPDKKIYHLCIVNLVIGTLYCAKGNYDFGISRV
                     IKSLEPYHKKLGTDTWYYAKRCFLSLLENMSKHTIMLRDSVIQECVQFLEHCELYGRN
                     IPAVIEQPLEEERMHTGKNTVTYESRKLRALIYEIIGWNV"
     regulatory      2594..2599
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ift70b"
                     /gene_synonym="2510042P03Rik; Tcc30b; Ttc30b"
                     /note="hexamer: AATAAT"
     regulatory      2597..2602
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ift70b"
                     /gene_synonym="2510042P03Rik; Tcc30b; Ttc30b"
                     /note="hexamer: AATGAA"
     polyA_site      2610
                     /gene="Ift70b"
                     /gene_synonym="2510042P03Rik; Tcc30b; Ttc30b"
                     /note="major polyA site"
     polyA_site      2614
                     /gene="Ift70b"
                     /gene_synonym="2510042P03Rik; Tcc30b; Ttc30b"
                     /note="major polyA site"
ORIGIN      
        1 gtttccggtt ggcctattgc cttggaaacc aggatgcaaa acaagctagg tgaatatggc
       61 agggctgagc agctcacaga tccccgacgg tgagttcaca gcagtggtgt acaggctcat
      121 ccgcgactcc cgctactcag aggcggtgca gctgctgagc gcagagctgc agaggagctc
      181 ccgcagccgc gcagggctgt cgctgctggc ctactgctac taccgcctgc aggagttcga
      241 gctcgctgca gagtgctatg agcagctgag ccagatgcac ccggaactcg agcagtaccg
      301 cctgtaccag gcccaggcac tgtacaaggc ctgcctgtat ccagaggcca ccagggtcgc
      361 cttcctcctg gacaaccccg cctatcagac tcgagtcctt cgtctccagg ctgctatcaa
      421 gtacagtgaa ggtgacctcc caggagccag gagcctggtg gagcagctgc tgagtgggga
      481 aggtgtagag gacagtggag gggagagtga ttatgatggt cagatcaacc taggttgtct
      541 gctctacaaa gagggacact atgaagctgc ctgttccaag ttcttagcgg ccctgcaggc
      601 ttctggctac cagcctgacc tttcctacaa cttggctttg gcctattaca gcagtcggca
      661 gtacgcgcct gctctgaagc atatcgctga catcattgag cgtggcatcc gtcaacaccc
      721 agaactcggt gtgggcatga ccacggaggg cattgatgtt cgcagtgttg gcaacactat
      781 agtccttcac cagactgctc tggtcgaagc cttcaacctc aaggcagcca tagagtacca
      841 gctgagaaac tacgaggcag cccaggaagc cctcactgac atgccaccca gagcagagga
      901 agagctggac cccgtaaccc tccacaacca ggctctgatg aacatggatg ccaagcccac
      961 agagggcttt gaaaagctcc agtttctgct ccagcagaac cccttccccc cagagacctt
     1021 tggcaacctg ctgctgctct actgtaaata tgagtatttt gacctggcag ctgatgtcct
     1081 ggcagaaaat gcccacttga cttacaagtt cctcacaccc tatctctatg acttcttgga
     1141 tgccatgatc acttgccaga cagctcctga agaggctttc attaaacttg atgggttggc
     1201 tggcatgctg actgagcagc tccggaaact caccatacaa gtacaggatt caaggcatag
     1261 tagagatgat gaatctgcca aaaaggctgt gaatgaatat gatgaaactc ttgagaagta
     1321 tattcctgta ctgatggccc aggcaaaaat ctactggaac tttgagaatt acccaatggt
     1381 ggagaagatc ttccgcaaat ctgtggaatt ctgtaatgac catgatgtgt ggaagctgaa
     1441 tgtggcccat gtcctcttca tgcaggagaa caagtacaaa gaggccattg gtttctatga
     1501 gcccattgtc aagaagaatt atgataacat cctgagtgtc agtgctattg tgttagccaa
     1561 cctctgtgtt tcctatatca tgacaagtca aaatgaggaa gctgaggagc tcatgaggaa
     1621 gattgagaag gaggaggaac aactctctta tggtgaccca gacaagaaaa tctaccacct
     1681 ttgcattgtg aatttggtga taggaactct gtattgtgcc aaaggaaact atgactttgg
     1741 catctctcgg gttatcaaaa gcctggagcc ttaccataaa aagctaggca ccgatacatg
     1801 gtattatgcc aagagatgtt tcctgtcctt actagagaac atgtcaaagc acacaattat
     1861 gctaagggac agtgtcattc aagaatgtgt gcagtttcta gagcactgtg aactttatgg
     1921 tagaaacatt ccagctgtta tagaacagcc cttggaggaa gaaagaatgc acactgggaa
     1981 gaatacagtc acatatgaat caagaaagtt gagggctctg atttatgaga taattggatg
     2041 gaatgtgtaa ttaccgctga caatttgtat catgatgact ttctatgtac attttcagtt
     2101 tttcctgtat ctagcttttg ctatttgtat ttgctacttg tgagactttg tacactttag
     2161 tgtaacaaaa gcactattcg atataacctg cacttttaaa tcctgtcaag tgagattgtg
     2221 taagaaccca ggccctagaa agtactttgg aacttttaaa actgagaaag atgttgtttc
     2281 tatcatgttt tctccatttt tgtttggttt tgatgtatct tggacaacct ttgctattat
     2341 gttatccagg gaccagacac taagttcaga acttagtcgt ccataacgtc ttcttgtaat
     2401 cactccaacg actgtgtttt ctctttgcac aactccccat gattttatag agaatttaga
     2461 gtgtttgaca gttttccaat acagatataa taatttgtac agattaaatt tcttaggtaa
     2521 taattggttt tgctagtttt caagattcag taaattcact taataaacac taataaataa
     2581 ataatcacta ataaataatg aaaaagaaaa gaaaaaaaaa aaaaaaaaaa aaaa
//
