LOCUS       NM_001199843             825 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus intraflagellar transport 43 (Ift43), transcript
            variant 1, mRNA.
ACCESSION   NM_001199843
VERSION     NM_001199843.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 825)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 825)
  AUTHORS   Agbu,S.O., Liang,Y., Liu,A. and Anderson,K.V.
  TITLE     The small GTPase RSG1 controls a final step in primary cilia
            initiation
  JOURNAL   J Cell Biol 217 (1), 413-427 (2018)
   PUBMED   29038301
REFERENCE   3  (bases 1 to 825)
  AUTHORS   Fu,W., Wang,L., Kim,S., Li,J. and Dynlacht,B.D.
  TITLE     Role for the IFT-A Complex in Selective Transport to the Primary
            Cilium
  JOURNAL   Cell Rep 17 (6), 1505-1517 (2016)
   PUBMED   27806291
REFERENCE   4  (bases 1 to 825)
  AUTHORS   Broekhuis,J.R., Verhey,K.J. and Jansen,G.
  TITLE     Regulation of cilium length and intraflagellar transport by the
            RCK-kinases ICK and MOK in renal epithelial cells
  JOURNAL   PLoS One 9 (9), e108470 (2014)
   PUBMED   25243405
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 825)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   6  (bases 1 to 825)
  AUTHORS   Mukhopadhyay,S., Wen,X., Chih,B., Nelson,C.D., Lane,W.S.,
            Scales,S.J. and Jackson,P.K.
  TITLE     TULP3 bridges the IFT-A complex and membrane phosphoinositides to
            promote trafficking of G protein-coupled receptors into primary
            cilia
  JOURNAL   Genes Dev 24 (19), 2180-2193 (2010)
   PUBMED   20889716
REFERENCE   7  (bases 1 to 825)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC134328.2, CF751010.1 and BE987571.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC034668.1, CK795561.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                AC134328.2         159027-159063
            38-674              CF751010.1         1-637
            675-825             BE987571.1         1-151               c
FEATURES             Location/Qualifiers
     source          1..825
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 40.16 cM"
     gene            1..825
                     /gene="Ift43"
                     /gene_synonym="1700019E19Rik"
                     /note="intraflagellar transport 43"
                     /db_xref="GeneID:76411"
                     /db_xref="MGI:MGI:1923661"
     exon            1..80
                     /gene="Ift43"
                     /gene_synonym="1700019E19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..647
                     /gene="Ift43"
                     /gene_synonym="1700019E19Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     intraflagellar transport protein 43 homolog;
                     intraflagellar transport 43 homolog"
                     /codon_start=1
                     /product="intraflagellar transport protein 43 homolog
                     isoform 1"
                     /protein_id="NP_001186772.1"
                     /db_xref="CCDS:CCDS88375.1"
                     /db_xref="GeneID:76411"
                     /db_xref="MGI:MGI:1923661"
                     /translation="MDDLLDLGEERRRSSATSGAKMGRRAHQESTQAENYLNSKNSSL
                     TQTGEAPPPKPPRRQGGWADDSMKMAKLGKKVSEEMEDHRLRQQNLMGSDDDDIPVIP
                     DLEDVQEEDFVLQVASPPSIQVNRVMTYRDLDNDLMKYSAFQTLDGEIDLKLLTKVLA
                     PEHEVREDDVGWDWDHLYTEVSSELLTEWDLLRAEKEDPVGPSRYI"
     exon            81..173
                     /gene="Ift43"
                     /gene_synonym="1700019E19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            174..238
                     /gene="Ift43"
                     /gene_synonym="1700019E19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            239..271
                     /gene="Ift43"
                     /gene_synonym="1700019E19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            272..315
                     /gene="Ift43"
                     /gene_synonym="1700019E19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            316..388
                     /gene="Ift43"
                     /gene_synonym="1700019E19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            389..464
                     /gene="Ift43"
                     /gene_synonym="1700019E19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            465..527
                     /gene="Ift43"
                     /gene_synonym="1700019E19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            528..809
                     /gene="Ift43"
                     /gene_synonym="1700019E19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      788..793
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ift43"
                     /gene_synonym="1700019E19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      809
                     /gene="Ift43"
                     /gene_synonym="1700019E19Rik"
                     /note="major polyA site"
ORIGIN      
        1 aggaagtgac atcagctgcc gcggcgatgg acgatttact ggacctgggc gaggagagac
       61 gtcgcagctc ggccacctcc ggggccaaga tgggacgccg ggctcatcag gagtcgactc
      121 aggctgagaa ttacttaaac agcaagaatt cttcactgac tcagactgga gaggctcccc
      181 caccgaaacc acctcgaagg cagggaggct gggcggatga ctccatgaag atggcgaaat
      241 tgggaaagaa agtttctgaa gagatggaag atcaccgcct ccgacagcag aacctgatgg
      301 ggtcagacga cgacgatatt cctgtgatcc cagacctgga agatgtgcag gaggaagact
      361 ttgtgctaca ggtggcgtct cctccaagta tccaggtaaa ccgagtgatg acctaccgtg
      421 acctggacaa tgacctcatg aagtactcgg cctttcagac tttggatgga gaaattgacc
      481 tgaaactcct caccaaagtg ctggccccag agcatgaagt gcgagaggat gatgtgggct
      541 gggactggga ccatctgtac accgaggtgt cctcagagct cctcactgag tgggacctgc
      601 tgcgggcaga gaaggaggat cctgtgggac catctaggta catctgaccc aggagcatca
      661 ctgagcattt gaacaaatgc aagaagtctc aaaccaagag agcttgcaag cagcttacag
      721 tttttatacg gaacattttg taatagaata tttattttca gtaggacaca tctgagcagt
      781 ctaattcaat aaatgacttt attctgtgaa aaaaaaaaaa aaaaa
//
