LOCUS       NM_025903               1980 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus interferon-related developmental regulator 2 (Ifrd2),
            mRNA.
ACCESSION   NM_025903
VERSION     NM_025903.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1980)
  AUTHORS   Vietor,I., Cikes,D., Piironen,K., Vasakou,T., Heimdorfer,D.,
            Gstir,R., Erlacher,M.D., Tancevski,I., Eller,P., Demetz,E.,
            Hess,M.W., Kuhn,V., Degenhart,G., Rozman,J., Klingenspor,M., Hrabe
            de Angelis,M., Valovka,T. and Huber,L.A.
  TITLE     The negative adipogenesis regulator Dlk1 is transcriptionally
            regulated by Ifrd1 (TIS7) and translationally by its orthologue
            Ifrd2 (SKMc15)
  JOURNAL   Elife 12, e88350 (2023)
   PUBMED   37603466
  REMARK    GeneRIF: The negative adipogenesis regulator Dlk1 is
            transcriptionally regulated by Ifrd1 (TIS7) and translationally by
            its orthologue Ifrd2 (SKMc15).
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1980)
  AUTHORS   Jadin,L., Wu,X., Ding,H., Frost,G.I., Onclinx,C., Triggs-Raine,B.
            and Flamion,B.
  TITLE     Skeletal and hematological anomalies in HYAL2-deficient mice: a
            second type of mucopolysaccharidosis IX?
  JOURNAL   FASEB J 22 (12), 4316-4326 (2008)
   PUBMED   18772348
REFERENCE   3  (bases 1 to 1980)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   4  (bases 1 to 1980)
  AUTHORS   Shuttleworth,T.L., Wilson,M.D., Wicklow,B.A., Wilkins,J.A. and
            Triggs-Raine,B.L.
  TITLE     Characterization of the murine hyaluronidase gene region reveals
            complex organization and cotranscription of Hyal1 with downstream
            genes, Fus2 and Hyal3
  JOURNAL   J Biol Chem 277 (25), 23008-23018 (2002)
   PUBMED   11929860
REFERENCE   5  (bases 1 to 1980)
  AUTHORS   Lerman,M.I. and Minna,J.D.
  TITLE     The 630-kb lung cancer homozygous deletion region on human
            chromosome 3p21.3: identification and evaluation of the resident
            candidate tumor suppressor genes. The International Lung Cancer
            Chromosome 3p21.3 Tumor Suppressor Gene Consortium
  JOURNAL   Cancer Res 60 (21), 6116-6133 (2000)
   PUBMED   11085536
REFERENCE   6  (bases 1 to 1980)
  AUTHORS   Buanne,P., Incerti,B., Guardavaccaro,D., Avvantaggiato,V.,
            Simeone,A. and Tirone,F.
  TITLE     Cloning of the human interferon-related developmental regulator
            (IFRD1) gene coding for the PC4 protein, a member of a novel family
            of developmentally regulated genes
  JOURNAL   Genomics 51 (2), 233-242 (1998)
   PUBMED   9722946
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK007687.1.
            
            On Apr 5, 2007 this sequence version replaced NM_025903.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK007687.1, AK166130.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1980              AK007687.1         2-1981
FEATURES             Location/Qualifiers
     source          1..1980
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 58.24 cM"
     gene            1..1980
                     /gene="Ifrd2"
                     /gene_synonym="1810034A24Rik; SKMc15"
                     /note="interferon-related developmental regulator 2"
                     /db_xref="GeneID:15983"
                     /db_xref="MGI:MGI:1316708"
     exon            1..229
                     /gene="Ifrd2"
                     /gene_synonym="1810034A24Rik; SKMc15"
                     /inference="alignment:Splign:2.1.0"
     CDS             172..1497
                     /gene="Ifrd2"
                     /gene_synonym="1810034A24Rik; SKMc15"
                     /codon_start=1
                     /product="interferon-related developmental regulator 2"
                     /protein_id="NP_080179.1"
                     /db_xref="CCDS:CCDS23500.1"
                     /db_xref="GeneID:15983"
                     /db_xref="MGI:MGI:1316708"
                     /translation="MPRARKGNALRKGGQRRGGGARSSTQADSGSSEDEAASEARSTT
                     SDCPSLLSATTEDCLGGEAVDEQSQQENLEEKLKGYVDCLTDKSAKTRQGALESLRLA
                     LASRLLPDFLLERSLTLADALEKCLKKGKGEEQALAAAVLGILCVQLGPGPKGEELFR
                     SLQPLLISVLSDSTASPTARLHCASALGLGCYVAATDVQDLVSCLACLEGVFSWSCGT
                     SGSAASLVPASLHGLLCAALQAWALLLTICPGTHISHILDRQLPRLPQLLSSESVNLR
                     IAAGEAIALLFELARDLEEDFVYEDMEALCGSLRTLATDSNKYRAKVDRRRQRSIFRA
                     VLHFVEGGECEEETVRFGLEVLYIDSWARHRIYTAFKDVLGSGIHYHLQNNELLRDIF
                     GLGPVLVLDAAALKACKISRFEKHLYNAAAFKARTKARSRARDKRADIL"
     exon            230..349
                     /gene="Ifrd2"
                     /gene_synonym="1810034A24Rik; SKMc15"
                     /inference="alignment:Splign:2.1.0"
     exon            350..434
                     /gene="Ifrd2"
                     /gene_synonym="1810034A24Rik; SKMc15"
                     /inference="alignment:Splign:2.1.0"
     exon            435..559
                     /gene="Ifrd2"
                     /gene_synonym="1810034A24Rik; SKMc15"
                     /inference="alignment:Splign:2.1.0"
     exon            560..717
                     /gene="Ifrd2"
                     /gene_synonym="1810034A24Rik; SKMc15"
                     /inference="alignment:Splign:2.1.0"
     exon            718..768
                     /gene="Ifrd2"
                     /gene_synonym="1810034A24Rik; SKMc15"
                     /inference="alignment:Splign:2.1.0"
     exon            769..947
                     /gene="Ifrd2"
                     /gene_synonym="1810034A24Rik; SKMc15"
                     /inference="alignment:Splign:2.1.0"
     exon            948..1053
                     /gene="Ifrd2"
                     /gene_synonym="1810034A24Rik; SKMc15"
                     /inference="alignment:Splign:2.1.0"
     exon            1054..1191
                     /gene="Ifrd2"
                     /gene_synonym="1810034A24Rik; SKMc15"
                     /inference="alignment:Splign:2.1.0"
     exon            1192..1320
                     /gene="Ifrd2"
                     /gene_synonym="1810034A24Rik; SKMc15"
                     /inference="alignment:Splign:2.1.0"
     exon            1321..1416
                     /gene="Ifrd2"
                     /gene_synonym="1810034A24Rik; SKMc15"
                     /inference="alignment:Splign:2.1.0"
     exon            1417..1980
                     /gene="Ifrd2"
                     /gene_synonym="1810034A24Rik; SKMc15"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      1980
                     /gene="Ifrd2"
                     /gene_synonym="1810034A24Rik; SKMc15"
                     /note="putative"
ORIGIN      
        1 gacagggcgg ggcgcctcac gaagatggtg gcgcgcgcgg cgtgtggctc ctgtcgtcct
       61 cgccagtctc agctcagcac acgggccagc gtttcgctgg tttggagtcc ccgccctccg
      121 ggtccctgac cccgcgcccc attcccgtgt tcccaattct cggttccagg aatgcctcgt
      181 gctcggaagg gcaatgcgct ccgcaagggc ggtcagcgcc gtggaggagg tgccaggagc
      241 agtacccagg ctgactctgg ctccagtgag gatgaagcgg ccagtgaggc ccggagcacc
      301 accagtgact gtcccagcct tctcagcgcc accacagagg actgcctggg tggcgaagcg
      361 gtggacgaac agagccagca ggaaaacctg gaggagaagc tgaaaggtta tgtggactgc
      421 ctgactgaca agagtgccaa gacccgtcaa ggagccctgg agagcctgcg cctggccctg
      481 gcctcccgcc tacttccgga ctttctgctg gagcgcagcc tcactctggc ggatgccctg
      541 gaaaagtgcc ttaagaaagg gaagggtgaa gaacaggctc tggctgctgc tgtgctaggc
      601 attctctgtg tgcagttggg ccctggaccc aagggcgagg agctgttccg tagcctgcag
      661 cccttgctca tctcggtgct cagtgacagt acagcaagcc ccactgcccg gctccattgt
      721 gcttctgctc ttggcttggg ttgctatgtg gctgccaccg acgtccagga cctggtctct
      781 tgcttggcct gcttggaagg tgttttcagc tggtcctgtg gcactagtgg ctctgcggcg
      841 tctctggttc ccgccagcct ccatggcctt ctctgtgctg ccctgcaggc ctgggcattg
      901 ctgctcacca tctgtcctgg tacccacatc agccatatcc ttgacaggca gctgccccgg
      961 ctgccccagc tcttgtccag tgaaagtgtg aacctgcgga ttgctgctgg tgaagccatc
     1021 gcgctactct ttgagcttgc ccgggacctt gaggaggact tcgtctatga agacatggag
     1081 gccctctgtg gatctctgcg taccctagcc accgacagca ataagtaccg tgccaaggtt
     1141 gaccggcggc gccagcgctc cattttccga gctgtgctgc actttgttga gggtggtgaa
     1201 tgtgaggagg agacagtccg cttcggactg gaagtgctct acatagacag ctgggctcgc
     1261 caccgcatct acacagcctt caaagatgtg ttgggctctg gcatacacta tcacctccag
     1321 aacaatgagc ttctccgtga catctttggc ctgggccccg tgctagtgtt ggatgctgct
     1381 gccctgaagg cctgcaagat ttcacgcttt gaaaagcacc tgtacaatgc tgcagccttc
     1441 aaagcccgga ccaaggcccg tagtcgtgca agggacaagc gggcagatat cttgtgaatc
     1501 agactggcca acgagaaggc tacccatacc ataccatatt tttaacagaa gacagtgcaa
     1561 gaactggtcc ctgccagtga ttgtcacttt atttttttaa tgatgaaacc aaaaatagac
     1621 aaatgtggga gggtcaaggg atcaggacac ttagactcaa gccctttgta tgtgcactca
     1681 gctctgtggc tgtggcctct tcctgtcctg tctcaggtaa aaccaaatgt gtgccggtcc
     1741 tggagggcta acggtcctag aggactaacc taggaccaac gggcagggtg ggtggtgaga
     1801 aaggaccatc cctgttttat agaccttgcc ccactccccc acccccaccc ccgaccgggg
     1861 ctgcttccct tgggggtctg gcacctggcc tccatggcat agggtaggca aagctgccta
     1921 taatggatgt gtgtgctggt ttattaaaga taagagagaa ttaaacgata cttagccccc
//
