LOCUS       NM_008336                670 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus interferon alpha B (Ifnab), mRNA.
ACCESSION   NM_008336
VERSION     NM_008336.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 670)
  AUTHORS   Hervas-Stubbs S, Rueda P, Lopez L and Leclerc C.
  TITLE     Insect baculoviruses strongly potentiate adaptive immune responses
            by inducing type I IFN
  JOURNAL   J Immunol 178 (4), 2361-2369 (2007)
   PUBMED   17277142
  REMARK    Erratum:[J Immunol. 2007 May 15;178(10):6653]
REFERENCE   2  (bases 1 to 670)
  AUTHORS   Chen J, Baig E and Fish EN.
  TITLE     Diversity and relatedness among the type I interferons
  JOURNAL   J Interferon Cytokine Res 24 (12), 687-698 (2004)
   PUBMED   15684736
REFERENCE   3  (bases 1 to 670)
  AUTHORS   Schiavoni G, Mauri C, Carlei D, Belardelli F, Pastoris MC and
            Proietti E.
  TITLE     Type I IFN protects permissive macrophages from Legionella
            pneumophila infection through an IFN-gamma-independent pathway
  JOURNAL   J Immunol 173 (2), 1266-1275 (2004)
   PUBMED   15240719
REFERENCE   4  (bases 1 to 670)
  AUTHORS   Honda K, Mizutani T and Taniguchi T.
  TITLE     Negative regulation of IFN-alpha/beta signaling by IFN regulatory
            factor 2 for homeostatic development of dendritic cells
  JOURNAL   Proc Natl Acad Sci U S A 101 (8), 2416-2421 (2004)
   PUBMED   14983024
  REMARK    GeneRIF: IFN regulatory factor 2 is involved in the negative
            regulation of IFN-alpha/beta signaling.
REFERENCE   5  (bases 1 to 670)
  AUTHORS   Wang Y, Wang Z, Zhou M, Cai J, Sun L, Liu X, Daugherty BL and
            Pestka S.
  TITLE     Sequencing and bacterial expression of a novel murine alpha
            interferon gene
  JOURNAL   Sci China C Life Sci 40 (3), 277-283 (1997)
   PUBMED   18726328
REFERENCE   6  (bases 1 to 670)
  AUTHORS   Hamilton JA, Whitty GA, Kola I and Hertzog PJ.
  TITLE     Endogenous IFN-alpha beta suppresses colony-stimulating factor
            (CSF)-1-stimulated macrophage DNA synthesis and mediates inhibitory
            effects of lipopolysaccharide and TNF-alpha
  JOURNAL   J Immunol 156 (7), 2553-2557 (1996)
   PUBMED   8786318
REFERENCE   7  (bases 1 to 670)
  AUTHORS   Hertzog PJ, Hwang SY and Kola I.
  TITLE     Role of interferons in the regulation of cell proliferation,
            differentiation, and development
  JOURNAL   Mol Reprod Dev 39 (2), 226-232 (1994)
   PUBMED   7530016
  REMARK    Review article
REFERENCE   8  (bases 1 to 670)
  AUTHORS   Su YH, Oakes JE and Lausch RN.
  TITLE     Mapping the genetic region coding for herpes simplex virus
            resistance to mouse interferon alpha/beta
  JOURNAL   J Gen Virol 74 (Pt 11), 2325-2332 (1993)
   PUBMED   8245849
REFERENCE   9  (bases 1 to 670)
  AUTHORS   Politis AD, Sivo J and Vogel SN.
  TITLE     Multiple pathways of interferon-induced gene expression in murine
            macrophages
  JOURNAL   J Leukoc Biol 53 (5), 583-590 (1993)
   PUBMED   7684767
REFERENCE   10 (bases 1 to 670)
  AUTHORS   Daugherty,B., Martin-Zanca,D., Kelder,B., Collier,K., Seamans,T.C.,
            Hotta,K. and Pestka,S.
  TITLE     Isolation and bacterial expression of a murine alpha leukocyte
            interferon gene
  JOURNAL   J Interferon Res 4 (4), 635-643 (1984)
   PUBMED   6094686
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC116862.1 and AL928605.22.
            
            On Sep 1, 2006 this sequence version replaced NM_008336.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC116862.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-352               BC116862.1         1-352
            353-436             AL928605.22        52400-52483         c
            437-670             BC116862.1         437-670
FEATURES             Location/Qualifiers
     source          1..670
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 42.02 cM"
     gene            1..670
                     /gene="Ifnab"
                     /gene_synonym="If1ai8"
                     /note="interferon alpha B"
                     /db_xref="GeneID:15974"
                     /db_xref="MGI:MGI:1097683"
     exon            1..670
                     /gene="Ifnab"
                     /gene_synonym="If1ai8"
                     /inference="alignment:Splign:2.1.0"
     CDS             42..614
                     /gene="Ifnab"
                     /gene_synonym="If1ai8"
                     /note="interferon alpha family, gene B; interferon 1ai8"
                     /codon_start=1
                     /product="interferon alpha family, gene B precursor"
                     /protein_id="NP_032362.2"
                     /db_xref="CCDS:CCDS18327.1"
                     /db_xref="GeneID:15974"
                     /db_xref="MGI:MGI:1097683"
                     /translation="MARLSTFLMVLAVMSYWSTCPLGCDLPQTHNLRNKRALTLLVQM
                     RRLSPLSCLKDRKDFGFPQEKVDAQQIQEAQAIPVLTELTQQMLTLFTSKASSAAWNA
                     TLLDSFCNDLHQQLNDLKTCLMQEVGVQESPLTQEDSLLAVRKYFHSITVYLREKKHS
                     PCAWEVVRAEVWRALSSSAKLLASLSEEKE"
ORIGIN      
        1 ccaaacagcc cagaagacca gcagcattgg caatattcac catggctagg ctcagcactt
       61 tcctaatggt cctggcagtg atgagctact ggtcaacctg ccctctagga tgtgacctgc
      121 ctcagactca taacctcagg aacaagagag ccttgacact cctggtacaa atgaggagac
      181 tctcccctct ctcctgcctg aaggacagga aggacttcgg attcccccag gagaaggtgg
      241 atgcccagca gatccaggag gctcaagcca tccctgtcct gactgagctg acccagcaga
      301 tgctgaccct cttcacatca aaggcttcat ctgctgcttg gaatgcaacc ctactagact
      361 cattctgcaa tgacctccac cagcaactca atgacctgaa aacctgtctg atgcaggagg
      421 tgggggtgca ggaatctccc ctgacccagg aagactccct gctggctgtg aggaaatact
      481 tccacagcat cactgtgtac ctgagagaga agaaacacag cccctgtgcc tgggaagtgg
      541 tcagagcaga agtctggaga gccctgtctt cctcagccaa gttgctggca agtctgagtg
      601 aggagaagga gtgagtctga gacccagtgg agagaatctc ctggactagg acactgcacc
      661 tctctgccca
//
