LOCUS       NM_010504                978 bp    mRNA    linear   ROD 07-AUG-2024
DEFINITION  Mus musculus interferon alpha 4 (Ifna4), mRNA.
ACCESSION   NM_010504
VERSION     NM_010504.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 978)
  AUTHORS   Imai,T., Lin,J., Kaya,G.G., Ju,E., Kondylis,V., Kelepouras,K.,
            Liccardi,G., Kim,C. and Pasparakis,M.
  TITLE     The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death
            and inflammation
  JOURNAL   Immunity 57 (7), 1497-1513 (2024)
   PUBMED   38744293
REFERENCE   2  (bases 1 to 978)
  AUTHORS   Geng,X., Zhang,C., Li,M., Wang,J., Ji,F., Feng,H., Xing,M., Li,F.,
            Zhang,L., Li,W., Chen,Z., Hickson,I.D., Shen,H. and Ying,S.
  TITLE     PICH Supports Embryonic Hematopoiesis by Suppressing a
            cGAS-STING-Mediated Interferon Response
  JOURNAL   Adv Sci (Weinh) 9 (7), e2103837 (2022)
   PUBMED   35037428
REFERENCE   3  (bases 1 to 978)
  AUTHORS   Onizawa,H., Kato,H., Kimura,H., Kudo,T., Soda,N., Shimizu,S.,
            Funabiki,M., Yagi,Y., Nakamoto,Y., Priller,J., Nishikomori,R.,
            Heike,T., Yan,N., Tsujimura,T., Mimori,T. and Fujita,T.
  TITLE     Aicardi-Goutieres syndrome-like encephalitis in mutant mice with
            constitutively active MDA5
  JOURNAL   Int Immunol 33 (4), 225-240 (2021)
   PUBMED   33165593
REFERENCE   4  (bases 1 to 978)
  AUTHORS   Liu,T.T., Yang,Q., Li,M., Zhong,B., Ran,Y., Liu,L.L., Yang,Y.,
            Wang,Y.Y. and Shu,H.B.
  TITLE     LSm14A Plays a Critical Role in Antiviral Immune Responses by
            Regulating MITA Level in a Cell-Specific Manner
  JOURNAL   J Immunol 196 (12), 5101-5111 (2016)
   PUBMED   27183626
REFERENCE   5  (bases 1 to 978)
  AUTHORS   Gerlach,N., Gibbert,K., Alter,C., Nair,S., Zelinskyy,G., James,C.M.
            and Dittmer,U.
  TITLE     Anti-retroviral effects of type I IFN subtypes in vivo
  JOURNAL   Eur J Immunol 39 (1), 136-146 (2009)
   PUBMED   19130550
REFERENCE   6  (bases 1 to 978)
  AUTHORS   Morin,P., Genin,P., Doly,J. and Civas,A.
  TITLE     The virus-induced factor VIF differentially recognizes the
            virus-responsive modules of the mouse IFNA4 gene promoter
  JOURNAL   J Interferon Cytokine Res 22 (1), 77-86 (2002)
   PUBMED   11846978
  REMARK    GeneRIF: IFN regulatory factor-3 is a component of virus-induced
            factor which binds the virus responsive element VRE-A4 in the IFNA4
            promotor
REFERENCE   7  (bases 1 to 978)
  AUTHORS   Coleman,M., Muller,S., Quezada,A., Mendiratta,S.K., Wang,J.,
            Thull,N.M., Bishop,J., Matar,M., Mester,J. and Pericle,F.
  TITLE     Nonviral interferon alpha gene therapy inhibits growth of
            established tumors by eliciting a systemic immune response
  JOURNAL   Hum Gene Ther 9 (15), 2223-2230 (1998)
   PUBMED   9794206
REFERENCE   8  (bases 1 to 978)
  AUTHORS   Hughes,T.K. Jr., Chin,R., Tyring,S.K. and Rady,P.L.
  TITLE     Distinction of mouse interferon-alpha subtypes by polymerase chain
            reaction utilizing consensus primers and type-specific
            oligonucleotide probes
  JOURNAL   J Interferon Res 14 (3), 117-120 (1994)
   PUBMED   7523540
REFERENCE   9  (bases 1 to 978)
  AUTHORS   Kelley,K.A. and Pitha,P.M.
  TITLE     Characterization of a mouse interferon gene locus I. Isolation of a
            cluster of four alpha interferon genes
  JOURNAL   Nucleic Acids Res 13 (3), 805-823 (1985)
   PUBMED   2987811
REFERENCE   10 (bases 1 to 978)
  AUTHORS   Zwarthoff,E.C., Mooren,A.T. and Trapman,J.
  TITLE     Organization, structure and expression of murine interferon alpha
            genes
  JOURNAL   Nucleic Acids Res 13 (3), 791-804 (1985)
   PUBMED   2987810
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928605.22.
            
            On Sep 13, 2022 this sequence version replaced NM_010504.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC119349.1, SRR17253011.7721478.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-978               AL928605.22        203362-204339
FEATURES             Location/Qualifiers
     source          1..978
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 42.03 cM"
     gene            1..978
                     /gene="Ifna4"
                     /gene_synonym="If1ai13; Ifa4"
                     /note="interferon alpha 4"
                     /db_xref="GeneID:15967"
                     /db_xref="MGI:MGI:107664"
     exon            1..978
                     /gene="Ifna4"
                     /gene_synonym="If1ai13; Ifa4"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..627
                     /gene="Ifna4"
                     /gene_synonym="If1ai13; Ifa4"
                     /note="MuIFN-alpha 4; IFN-alpha-4; interferon alpha
                     family, gene 4; interferon 1ai13"
                     /codon_start=1
                     /product="interferon alpha-4 precursor"
                     /protein_id="NP_034634.1"
                     /db_xref="CCDS:CCDS18346.1"
                     /db_xref="GeneID:15967"
                     /db_xref="MGI:MGI:107664"
                     /translation="MARLCAFLMILVMMSYYWSACSLGCDLPHTYNLGNKRALTVLEE
                     MRRLPPLSCLKDRKDFGFPLEKVDNQQIQKAQAILVLRDLTQQILNLFTSKDLSATWN
                     ATLLDSFCNDLHQQLNDLKACVMQEPPLTQEDSLLAVRTYFHRITVYLRKKKHSLCAW
                     EVIRAEVWRALSSSTNLLARLSEEKE"
ORIGIN      
        1 agagaacctg taggagaaga ctcaaaccca cagcccagag agtgaccagc atctacaaga
       61 cccacaatgg ctaggctctg tgctttcctc atgatcctgg taatgatgag ctactactgg
      121 tcagcctgtt ctctaggatg tgacctgcct cacacttata acctcgggaa caagagggcc
      181 ttgacagtcc tggaagaaat gagaagactc ccccctcttt cctgcctgaa ggacaggaag
      241 gattttggat tccccttgga gaaggtggat aaccaacaga tccagaaggc tcaagccatc
      301 cttgtgctaa gagatcttac ccagcagatt ttgaacctct tcacatcaaa agacttgtct
      361 gctacttgga atgcaactct actagactca ttctgcaatg acctccatca gcagctcaat
      421 gacctcaaag cctgtgtgat gcaggaacct cctctgaccc aggaagactc cctgctggct
      481 gtgaggacat acttccacag gatcactgtg tacctgagaa agaagaaaca cagcctctgt
      541 gcctgggagg tgatcagagc agaagtctgg agagccctct cttcctcaac caacttgctg
      601 gcaagactga gtgaggagaa ggagtgagtc ctgagacaaa gtgtggagag gacttttctg
      661 gaccagaaca ctgcatctca ctttataagc tctcctttaa aaactctcat aactttcata
      721 tatgagtaca aacaacctgc atagatgttt cagcaatctt gagcaattct tttcaatatg
      781 caaaaccgtg tttgtatctg aatccatttg ctctttctta tttgtttgtt tgtttattta
      841 tttatttatt tatttattgt gctattaata taatttaagg taattatgtt aaatatttca
      901 gtctcatatt tttaatatat catgttatca tttgtaatta acttattttc tattcaaata
      961 aatttgattc ataagaca
//
