LOCUS       NM_008333                647 bp    mRNA    linear   ROD 02-APR-2024
DEFINITION  Mus musculus interferon alpha 11 (Ifna11), mRNA.
ACCESSION   NM_008333
VERSION     NM_008333.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 647)
  AUTHORS   Gibbert,K., Joedicke,J.J., Meryk,A., Trilling,M., Francois,S.,
            Duppach,J., Kraft,A., Lang,K.S. and Dittmer,U.
  TITLE     Interferon-alpha subtype 11 activates NK cells and enables control
            of retroviral infection
  JOURNAL   PLoS Pathog 8 (8), e1002868 (2012)
   PUBMED   22912583
  REMARK    GeneRIF: a unique and subtype-specific activation of NK cells by
            IFN-alpha11.
REFERENCE   2  (bases 1 to 647)
  AUTHORS   Hervas-Stubbs,S., Rueda,P., Lopez,L. and Leclerc,C.
  TITLE     Insect baculoviruses strongly potentiate adaptive immune responses
            by inducing type I IFN
  JOURNAL   J Immunol 178 (4), 2361-2369 (2007)
   PUBMED   17277142
  REMARK    Erratum:[J Immunol. 2007 May 15;178(10):6653]
REFERENCE   3  (bases 1 to 647)
  AUTHORS   Nacionales,D.C., Kelly,K.M., Lee,P.Y., Zhuang,H., Li,Y.,
            Weinstein,J.S., Sobel,E., Kuroda,Y., Akaogi,J., Satoh,M. and
            Reeves,W.H.
  TITLE     Type I interferon production by tertiary lymphoid tissue developing
            in response to 2,6,10,14-tetramethyl-pentadecane (pristane)
  JOURNAL   Am J Pathol 168 (4), 1227-1240 (2006)
   PUBMED   16565497
  REMARK    GeneRIF: IFN-I from ectopic lymphoid tissue could play a role in
            the pathogenesis of experimental lupus in mice.
REFERENCE   4  (bases 1 to 647)
  AUTHORS   Chen,J., Baig,E. and Fish,E.N.
  TITLE     Diversity and relatedness among the type I interferons
  JOURNAL   J Interferon Cytokine Res 24 (12), 687-698 (2004)
   PUBMED   15684736
REFERENCE   5  (bases 1 to 647)
  AUTHORS   van Pesch,V., Lanaya,H., Renauld,J.C. and Michiels,T.
  TITLE     Characterization of the murine alpha interferon gene family
  JOURNAL   J Virol 78 (15), 8219-8228 (2004)
   PUBMED   15254193
REFERENCE   6  (bases 1 to 647)
  AUTHORS   Morin,P., Braganca,J., Bandu,M.T., Lin,R., Hiscott,J., Doly,J. and
            Civas,A.
  TITLE     Preferential binding sites for interferon regulatory factors 3 and
            7 involved in interferon-A gene transcription
  JOURNAL   J Mol Biol 316 (5), 1009-1022 (2002)
   PUBMED   11884139
  REMARK    GeneRIF: Preferential binding sites for interferon regulatory
            factors 3 and 7 involved in interferon-A gene transcription
REFERENCE   7  (bases 1 to 647)
  AUTHORS   Roffet,P., Lopez,S., Navarro,S., Bandu,M.T., Coulombel,C.,
            Vignal,M., Doly,J. and Vodjdani,G.
  TITLE     Identification of distal silencing elements in the murine
            interferon-A11 gene promoter
  JOURNAL   Biochem J 317 (Pt 3) (Pt 3), 697-706 (1996)
   PUBMED   8760352
REFERENCE   8  (bases 1 to 647)
  AUTHORS   Civas,A., Dion,M., Vodjdani,G. and Doly,J.
  TITLE     Repression of the murine interferon alpha 11 gene: identification
            of negatively acting sequences
  JOURNAL   Nucleic Acids Res 19 (16), 4497-4502 (1991)
   PUBMED   1886773
REFERENCE   9  (bases 1 to 647)
  AUTHORS   Coulombel,C., Vodjdani,G. and Doly,J.
  TITLE     Isolation and characterization of a novel interferon-alpha-encoding
            gene, IFN-alpha 11, within a murine IFN cluster
  JOURNAL   Gene 104 (2), 187-195 (1991)
   PUBMED   1655578
REFERENCE   10 (bases 1 to 647)
  AUTHORS   Navarro,S., Dion,M., Vodjdani,G., Berlot-Picard,F. and Doly,J.
  TITLE     Isolation and characterization of a functional murine interferon
            alpha gene which is not expressed in fibroblasts upon virus
            induction
  JOURNAL   J Gen Virol 70 (Pt 6), 1381-1389 (1989)
   PUBMED   2471809
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928605.22.
            
            On Oct 24, 2007 this sequence version replaced NM_008333.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC116872.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-647               AL928605.22        181486-182132
FEATURES             Location/Qualifiers
     source          1..647
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 42.03 cM"
     gene            1..647
                     /gene="Ifna11"
                     /gene_synonym="If1ai10; IFN-[a]11"
                     /note="interferon alpha 11"
                     /db_xref="GeneID:15964"
                     /db_xref="MGI:MGI:109210"
     exon            1..647
                     /gene="Ifna11"
                     /gene_synonym="If1ai10; IFN-[a]11"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..613
                     /gene="Ifna11"
                     /gene_synonym="If1ai10; IFN-[a]11"
                     /note="limitin; IFN-alpha-11; interferon alpha family,
                     gene 11; interferon 1ai10"
                     /codon_start=1
                     /product="interferon alpha-11 precursor"
                     /protein_id="NP_032359.2"
                     /db_xref="CCDS:CCDS38810.1"
                     /db_xref="GeneID:15964"
                     /db_xref="MGI:MGI:109210"
                     /translation="MARLCAFLMILIVMSYWSTCSLGCDLPHTYNLRNKRALKVLAQM
                     RRLTPLSCLKDRKDFGFPLEKVDAQQIQKAQSIPVLRDLTQQILNLFASKDSSAAWNA
                     TLLDSFCNDLHQQLNDLQGCLMQQVGVQESPLTQEDSLLAVRIYFHRITVFLREKKHS
                     PCAWEVVRAEVWRALSSSANVLGRLREEKA"
ORIGIN      
        1 cacacagtcc agagagccat caatatctgc aagacccata atggctaggc tctgtgcttt
       61 cctcatgatc ttgatagtga tgagctactg gtcaacctgt tctctaggat gcgatctgcc
      121 tcacacttat aacctcagga acaagagggc cttgaaggtc ctggcacaaa tgaggaggct
      181 cacccctctt tcctgcctaa aggacaggaa ggactttgga ttccccttgg agaaggtgga
      241 tgcccagcag atccagaagg ctcaatccat ccctgtgctg cgagatctta cccagcagat
      301 cttgaacctc ttcgcatcaa aggactcatc tgctgcttgg aatgcaaccc tcctagactc
      361 attctgcaat gacctccacc agcagctcaa tgacctgcaa ggttgtctga tgcagcaggt
      421 gggggtgcag gaatctcccc tgacccagga agactccctg ctggctgtga ggatatactt
      481 ccacaggatc actgtgttcc tgagagagaa gaaacacagc ccctgtgcct gggaggtggt
      541 cagagcagaa gtctggagag ccctgtcttc ctctgccaat gtgctgggaa gactgagaga
      601 agagaaggct tgagtcctga gaccaagtgt ggagagtcct cccctgg
//
