LOCUS       NM_001110517            2296 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus interferon induced protein with tetratricpeptide
            repeats 1B like 1 (Ifit1bl1), transcript variant 1, mRNA.
ACCESSION   NM_001110517
VERSION     NM_001110517.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2296)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2296)
  AUTHORS   Mears,H.V. and Sweeney,T.R.
  TITLE     Mouse Ifit1b is a cap1-RNA-binding protein that inhibits mouse
            coronavirus translation and is regulated by complexing with Ifit1c
  JOURNAL   J Biol Chem 295 (51), 17781-17801 (2020)
   PUBMED   33454014
  REMARK    GeneRIF: Mouse Ifit1b is a cap1-RNA-binding protein that inhibits
            mouse coronavirus translation and is regulated by complexing with
            Ifit1c.
REFERENCE   3  (bases 1 to 2296)
  AUTHORS   Fensterl,V. and Sen,G.C.
  TITLE     Interferon-induced Ifit proteins: their role in viral pathogenesis
  JOURNAL   J Virol 89 (5), 2462-2468 (2015)
   PUBMED   25428874
  REMARK    Review article
REFERENCE   4  (bases 1 to 2296)
  AUTHORS   Diamond,M.S. and Farzan,M.
  TITLE     The broad-spectrum antiviral functions of IFIT and IFITM proteins
  JOURNAL   Nat Rev Immunol 13 (1), 46-57 (2013)
   PUBMED   23237964
  REMARK    Review article
REFERENCE   5  (bases 1 to 2296)
  AUTHORS   Norman,B., Davis,J. and Piatigorsky,J.
  TITLE     Postnatal gene expression in the normal mouse cornea by SAGE
  JOURNAL   Invest Ophthalmol Vis Sci 45 (2), 429-440 (2004)
   PUBMED   14744882
REFERENCE   6  (bases 1 to 2296)
  AUTHORS   VanBuren,V., Piao,Y., Dudekula,D.B., Qian,Y., Carter,M.G.,
            Martin,P.R., Stagg,C.A., Bassey,U.C., Aiba,K., Hamatani,T.,
            Kargul,G.J., Luo,A.G., Kelso,J., Hide,W. and Ko,M.S.
  TITLE     Assembly, verification, and initial annotation of the NIA mouse
            7.4K cDNA clone set
  JOURNAL   Genome Res 12 (12), 1999-2003 (2002)
   PUBMED   12466305
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AA290456.1, BY094379.1, BB575849.1, DV551663.1, AC016791.23,
            AA175618.1, BX515248.1 and BQ553020.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes isoform 1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no quality transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BY094379.1, BB575849.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-42                AA290456.1         1-42
            43-68               BY094379.1         36-61
            69-155              AA290456.1         69-155
            156-200             BB575849.1         81-125
            201-523             DV551663.1         88-410
            524-1161            AC016791.23        42653-43290         c
            1162-1574           AA175618.1         1-413
            1575-1767           BX515248.1         346-538
            1768-2296           BQ553020.1         1-529               c
FEATURES             Location/Qualifiers
     source          1..2296
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 29.75 cM"
     gene            1..2296
                     /gene="Ifit1bl1"
                     /gene_synonym="Gm14446; Ifit1c"
                     /note="interferon induced protein with tetratricpeptide
                     repeats 1B like 1"
                     /db_xref="GeneID:667373"
                     /db_xref="MGI:MGI:3650685"
     exon            1..160
                     /gene="Ifit1bl1"
                     /gene_synonym="Gm14446; Ifit1c"
                     /inference="alignment:Splign:2.1.0"
     CDS             129..1541
                     /gene="Ifit1bl1"
                     /gene_synonym="Gm14446; Ifit1c"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="interferon induced protein with tetratricpeptide
                     repeats 1B like 1 isoform 1"
                     /protein_id="NP_001103987.1"
                     /db_xref="CCDS:CCDS50421.1"
                     /db_xref="GeneID:667373"
                     /db_xref="MGI:MGI:3650685"
                     /translation="MEQLLSPSNMSAKSHSCLIYDSLVELRCHFTWKLVIEKVDMPDL
                     EVRISETEFFDASYSIGMHNLLAYVRHLKGQQEEALQSLKEAEALIQSEQLSKRRLVT
                     WGNCAWLHYHRGSLAEAQVYLDKVEKVCKEFSSPFQYRLECAEMDCEEGWALLKCGIQ
                     NYKGAMACFAKALKVEPENPEYNAGYAVVAYRLDHIDGTSLQHLQKAVSVKPEDPYLK
                     VLLALKLQDLHKLEEAEKHIEETLPRISSQPYVFGYVAKFYRRKGLVKEALEFLGRAL
                     QKQPCSTFLHFQIGLCHKKRLIQIKKASNMQPRGEDRKRADQSIHLAICHFKRTLELK
                     PTYVMAYVTLAEMYIEKNQLKEAEDNFQKLLNMSNLEDHIQQEIHFRYGNFQQYYKKS
                     EEAAITHYLKGLKIEVTSHYRDKPLKALEKLAKRRKEDHVLENLGLLGFVYKLKGNTS
                     EAMSCYERALRLTGAVNPEF"
     exon            161..2296
                     /gene="Ifit1bl1"
                     /gene_synonym="Gm14446; Ifit1c"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2274..2279
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ifit1bl1"
                     /gene_synonym="Gm14446; Ifit1c"
                     /note="hexamer: AATAAA"
     polyA_site      2295
                     /gene="Ifit1bl1"
                     /gene_synonym="Gm14446; Ifit1c"
                     /note="major polyA site"
ORIGIN      
        1 attgccagtt tcagttagga actgagggtg tagcaaacct tctctatata aataccttgc
       61 ttatcctaga atccctagaa cacttttgat tgagtttgga agcatctctt ggcctggatt
      121 aaagtgctat ggagcaactt ctgagtccca gcaacatgag tgcaaaatct catagttgtc
      181 tcatctatga cagcctggtt gagctgagat gccatttcac atggaagttg gttatagaaa
      241 aggttgacat gcctgatttg gaagtaagaa tctcagagac tgagttcttt gatgccagct
      301 acagcatcgg gatgcacaac ctcctggcct acgtgaggca cctgaaaggc cagcaggagg
      361 aagccctgca gagcttgaaa gaagctgaag ccttgatcca gagcgagcag ttgagcaaga
      421 gaaggctggt gacctggggc aactgtgcct ggctgcatta ccacaggggc agcttggcag
      481 aagcccaggt ctacctggac aaggtggaga aggtgtgcaa ggaattttca agtcccttcc
      541 aatacaggct ggagtgtgct gagatggact gtgaggaagg ctgggccttg ttgaagtgtg
      601 gcatacaaaa ttataaagga gccatggcct gctttgcaaa ggctctgaaa gtggagccag
      661 aaaaccctga gtacaatgct ggctatgcag tcgtagccta tcgcctggat cacattgatg
      721 gcacttcgct ccaacattta cagaaggctg tcagcgtaaa accagaagat ccatacctta
      781 aagttctcct tgccctaaag cttcaggatt tacacaaact agaagaagca gaaaaacaca
      841 ttgaagaaac tctgcccagg atatcctcgc agccctatgt ctttggatat gtagccaaat
      901 tttaccgaag gaaaggattg gtgaaagaag ctcttgagtt ccttggcaga gccttgcaga
      961 aacaaccttg ctccaccttc ttgcatttcc agattggcct ttgccataag aaacgactga
     1021 ttcaaataaa gaaagcttca aacatgcaac caagagggga agatagaaaa agagcagacc
     1081 aatccatcca tttggctata tgtcatttta aacggacttt agaactgaaa cccacatatg
     1141 tgatggcata tgttactctg gctgaaatgt acattgagaa aaatcaacta aaagaagcag
     1201 aggacaattt tcagaaattg ttgaacatga gtaacttgga agatcatatt cagcaagaga
     1261 ttcacttccg gtatggcaac ttccaacaat actataagaa atcagaagag gcagccatca
     1321 cacattactt aaaaggccta aaaatagagg taacttctca ctacagggat aaacctctca
     1381 aggctttgga gaaactggct aaaagacgca aggaagatca tgtcctggaa aacttgggcc
     1441 tacttgggtt tgtctacaaa ctgaaaggga acacaagtga agccatgtca tgctatgaga
     1501 gggccctgag gctcacagga gcagtgaacc ctgagttttg aggaagagct tcttgagtgg
     1561 cttgttaagc gtgagcatga ctttctaatc tactagtctt ttccagctgt tgccttaact
     1621 atataaaccc ccatgaagca agatacagat gatgcctttt ctattgcttg cttttctaca
     1681 gccataattt atggttgagg gcctatgagt gtgtgacagg agtgtccatt ctcctgtcac
     1741 acatgctgga cattttcctt atgagtgtgc ctttaattgc atctcctata ccatcagtct
     1801 tcaagaaccc cgatcaaagg acacttgaca cattaaggct catttttcat gggatcttcc
     1861 aaacttcaac aacatctgac agcaaaataa atgagcaatg gtgagcatta aaagggagag
     1921 aaatgcaaga tatctttaca gtgtttcagt ccataggccc attttcatag gctttactgc
     1981 agccagaacc tgctggtcaa tgacccccaa gccaataatc aaagcatctt tttgtataaa
     2041 agtgtttgat tttagataat tgtggtggat ttctgtggtc tacatatatt ggcctttatt
     2101 cattactaag aaagatttaa tgcttcagga agatagaata aagcagtaac ctctgtggaa
     2161 tgtgccaaca acaacaaaaa caacaaaaaa tgacaaaatt tctactggag aatgttcaga
     2221 ctatgaagtg ttgtgtaata tcaccttgtt gctttcctaa cccaatcata ttcaataaaa
     2281 tctgctaata tcacag
//
