LOCUS       NM_008331               2638 bp    mRNA    linear   ROD 03-FEB-2024
DEFINITION  Mus musculus interferon-induced protein with tetratricopeptide
            repeats 1 (Ifit1), mRNA.
ACCESSION   NM_008331
VERSION     NM_008331.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2638)
  AUTHORS   Lu,Y.J., Deng,Y.T., Ko,H.H., Peng,H.H., Lee,H.C., Kuo,M.Y. and
            Cheng,S.J.
  TITLE     Lysyl oxidase-like 2 promotes stemness and enhances antitumor
            effects of gefitinib in head and neck cancer via IFIT1 and IFIT3
  JOURNAL   Cancer Sci 114 (10), 3957-3971 (2023)
   PUBMED   37496288
  REMARK    GeneRIF: Lysyl oxidase-like 2 promotes stemness and enhances
            antitumor effects of gefitinib in head and neck cancer via IFIT1
            and IFIT3.
REFERENCE   2  (bases 1 to 2638)
  AUTHORS   Zengeler,K.E., Shapiro,D.A., Bruch,K.R., Lammert,C.R., Ennerfelt,H.
            and Lukens,J.R.
  TITLE     SSRI treatment modifies the effects of maternal inflammation on in
            utero physiology and offspring neurobiology
  JOURNAL   Brain Behav Immun 108, 80-97 (2023)
   PUBMED   36343752
REFERENCE   3  (bases 1 to 2638)
  AUTHORS   Rupani,D.N., Thege,F.I., Chandra,V., Rajaei,H., Cowan,R.W.,
            Wormann,S.M., Le Roux,O., Malaney,P., Manning,S.L., Hashem,J.,
            Bailey-Lundberg,J., Rhim,A.D. and McAllister,F.
  TITLE     Adar1 deletion causes degeneration of the exocrine pancreas via
            Mavs-dependent interferon signaling
  JOURNAL   Development 150 (2) (2023)
   PUBMED   36458554
REFERENCE   4  (bases 1 to 2638)
  AUTHORS   Jiang,W., Zhang,Y., Sheng,Y., Liu,M., Du,C., Pan,X., Huang,C.,
            Li,J. and Wang,Y.
  TITLE     Overexpression of IFIT1 protects against LPS-induced acute lung
            injury via regulating CCL5-p65NF-kappaB signaling
  JOURNAL   Int Immunopharmacol 114, 109485 (2023)
   PUBMED   36446235
  REMARK    GeneRIF: Overexpression of IFIT1 protects against LPS-induced acute
            lung injury via regulating CCL5-p65NF-kappaB signaling.
REFERENCE   5  (bases 1 to 2638)
  AUTHORS   de Reuver,R., Verdonck,S., Dierick,E., Nemegeer,J., Hessmann,E.,
            Ahmad,S., Jans,M., Blancke,G., Van Nieuwerburgh,F., Botzki,A.,
            Vereecke,L., van Loo,G., Declercq,W., Hur,S., Vandenabeele,P. and
            Maelfait,J.
  TITLE     ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1
            activation
  JOURNAL   Nature 607 (7920), 784-789 (2022)
   PUBMED   35859175
REFERENCE   6  (bases 1 to 2638)
  AUTHORS   Williams,T.M., Williams,M.E., Kuick,R., Misek,D., McDonagh,K.,
            Hanash,S. and Innis,J.W.
  TITLE     Candidate downstream regulated genes of HOX group 13 transcription
            factors with and without monomeric DNA binding capability
  JOURNAL   Dev Biol 279 (2), 462-480 (2005)
   PUBMED   15733672
REFERENCE   7  (bases 1 to 2638)
  AUTHORS   Hui,D.J., Terenzi,F., Merrick,W.C. and Sen,G.C.
  TITLE     Mouse p56 blocks a distinct function of eukaryotic initiation
            factor 3 in translation initiation
  JOURNAL   J Biol Chem 280 (5), 3433-3440 (2005)
   PUBMED   15561726
  REMARK    GeneRIF: block different functions of eIF3 by binding to its
            different subunits.
REFERENCE   8  (bases 1 to 2638)
  AUTHORS   Smith,J.B. and Herschman,H.R.
  TITLE     The glucocorticoid attenuated response genes GARG-16, GARG-39, and
            GARG-49/IRG2 encode inducible proteins containing multiple
            tetratricopeptide repeat domains
  JOURNAL   Arch Biochem Biophys 330 (2), 290-300 (1996)
   PUBMED   8660659
REFERENCE   9  (bases 1 to 2638)
  AUTHORS   Smith,J.B. and Herschman,H.R.
  TITLE     Glucocorticoid-attenuated response genes encode intercellular
            mediators, including a new C-X-C chemokine
  JOURNAL   J Biol Chem 270 (28), 16756-16765 (1995)
   PUBMED   7622488
REFERENCE   10 (bases 1 to 2638)
  AUTHORS   Bluyssen,H.A., Vlietstra,R.J., Faber,P.W., Smit,E.M., Hagemeijer,A.
            and Trapman,J.
  TITLE     Structure, chromosome localization, and regulation of expression of
            the interferon-regulated mouse Ifi54/Ifi56 gene family
  JOURNAL   Genomics 24 (1), 137-148 (1994)
   PUBMED   7896268
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AK150424.1.
            
            [WARNING] On Apr 11, 2024 this sequence was replaced by
            NM_008331.4.
            
            On Apr 17, 2007 this sequence version replaced NM_008331.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK150424.1, AK151298.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2638              AK150424.1         2-2639
FEATURES             Location/Qualifiers
     source          1..2638
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="19"
                     /map="19 29.78 cM"
     gene            1..2638
                     /gene="Ifit1"
                     /gene_synonym="GARG-16; IFI-56K; Ifi56; ISG56; P56"
                     /note="interferon-induced protein with tetratricopeptide
                     repeats 1"
                     /db_xref="GeneID:15957"
                     /db_xref="MGI:MGI:99450"
     exon            1..99
                     /gene="Ifit1"
                     /gene_synonym="GARG-16; IFI-56K; Ifi56; ISG56; P56"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..1486
                     /gene="Ifit1"
                     /gene_synonym="GARG-16; IFI-56K; Ifi56; ISG56; P56"
                     /note="interferon-induced 56 kDa protein;
                     glucocorticoid-attenuated response gene 16 protein"
                     /codon_start=1
                     /product="interferon-induced protein with
                     tetratricopeptide repeats 1"
                     /protein_id="NP_032357.2"
                     /db_xref="CCDS:CCDS29766.1"
                     /db_xref="GeneID:15957"
                     /db_xref="MGI:MGI:99450"
                     /translation="MGENADGDQVMENLLQLRCHFTWKLLFENNDIPDLEVRISEQVQ
                     FLDIKNPLGMHNLLAYVRHLKGQQDEALQSLKEAEALIQSEQLSKRSLATWGNCAWLH
                     YHRGSLAEAQIYLDKVEKVCKEFSSPFRYRLECAEMDCEEGWALLKCGGGNYKQAMAC
                     FAKALKVEPENPEYNTGYAVVAYRQDLDDNFISLEPLRKAVRLNPEDPYLKVLLALKL
                     QDLGEHVEAEAHIEEALSSTSCQSYVIRYAAKYFRRKHRVDKALHLLNRALQASPSSG
                     YLHYQKGLCYKQQISQLRTSRNRQPRRQDNVQELAQQAIHEFQETLKLRPTFEMAYVC
                     MAEVQAEIHQYEEAERNFQKALNNKTLVAHIEQDIHLRYGRFLQFHKQSEDKAITLYL
                     KGLKVEEKSFAWRKLLTALEKVAERRVCQNVHLVESTSLLGLVYKLKGQEKNALFYYE
                     KALRLTGEMNPAF"
     exon            100..2638
                     /gene="Ifit1"
                     /gene_synonym="GARG-16; IFI-56K; Ifi56; ISG56; P56"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      2638
                     /gene="Ifit1"
                     /gene_synonym="GARG-16; IFI-56K; Ifi56; ISG56; P56"
                     /note="putative"
ORIGIN      
        1 gacagtctgc aagagagcag agagtcaagg caggtttctg aggagttctg ctctgctgaa
       61 aacccagaga acagctacca cctttacagc aaccatggga gagaatgctg atggtgacca
      121 ggtcatggag aatctgcttc agctgagatg tcacttcaca tggaagctgc tatttgaaaa
      181 taatgacata cctgatttgg aagtgagaat ctcagagcag gtccagttcc ttgacatcaa
      241 gaacccattg gggatgcaca acctcctggc ctacgtgagg cacctgaaag gccagcagga
      301 cgaagccctg cagagcttga aagaagctga agccttgatc cagagcgagc agctgagcaa
      361 gagaagcctg gcgacctggg gcaactgtgc ctggctgcat taccacaggg gcagcttggc
      421 agaagcccag atctacctgg acaaggtgga gaaggtgtgc aaggaatttt caagtccctt
      481 ccgctacagg ctggagtgtg ctgagatgga ctgtgaggaa ggctgggcct tgctgaagtg
      541 tggaggagga aattataaac aagccatggc ctgctttgcg aaggctctga aagtggagcc
      601 agaaaaccct gagtacaaca ctggctatgc agtcgtagcc tatcgccaag atttagatga
      661 caactttatt tctctagaac ctttgaggaa ggctgtccgg ttaaatccag aagatccata
      721 ccttaaagtt ctccttgccc taaagcttca ggatttagga gaacatgttg aagcagaagc
      781 acacattgaa gaagccctca gcagcacatc ttgccaaagc tatgtcattc gctatgcagc
      841 caaatatttc cgtaggaaac atcgcgtaga caaagctctt catcttctaa acagggcctt
      901 gcaggcatca ccttcctctg gctacttaca ttatcaaaaa gggctctgct acaagcaaca
      961 aatctcccaa ctgaggacat cccgaaacag gcagcccaga aggcaggaca atgtgcaaga
     1021 attggcacaa caggccattc atgaatttca agagactttg aaactgaggc ccacatttga
     1081 gatggcctat gtttgcatgg ctgaagtgca ggcagaaatt caccagtatg aagaagcaga
     1141 gagaaatttc cagaaggcac tgaacaacaa gaccctcgtg gctcacatag agcaggatat
     1201 tcacctccgc tatggccgtt tcctacagtt tcataagcag tcagaagaca aggcaatcac
     1261 cctctactta aaaggtctaa aagtggaaga gaagtccttt gcttggagga aactactgac
     1321 tgctttggag aaagtggctg aaagacgtgt ttgtcagaat gttcatcttg tagagagtac
     1381 cagccttctt gggctagtct acaaactgaa aggacaagag aaaaatgctc tgttttacta
     1441 tgagaaggca ctgaggctca ctggggaaat gaaccctgca ttctgaatgc agctcacctc
     1501 tgtgacgtta atatactcac aaccaagtgt tccaatgctc cttcctgatt tcttttccca
     1561 ggtctgtttt gttgttgttg ttgttcgttt tctttctgaa atgccaagta gcaaggtaca
     1621 ttttctcctg tgacttcttt ctggtctttc tgaccctgtc tagcaggcaa ttccatccca
     1681 aggatacata ctcacttaaa gatcacaact gattcctgct gttttggact cctgtgagct
     1741 gtagaatcac acaacctttt tccttatgtc tgtgcctttg gaacagatat cttccaccct
     1801 ttgctaatgt cctggacaaa aaagtctttg ccaaagaagg tatttttttt ttaatgtcac
     1861 cggaaatgct tattaccata caatttcaga gcaaaacaaa tgagcaaaga agaaagtttg
     1921 aaagcaaaag aggtcacaca ttactggaaa gatactaaga accaagaaga cttttggctt
     1981 actagagaat taaaatgaaa accctcctta ggtagtaaag tctgaaaatt acataaataa
     2041 cttctttcaa tatttatatg ctaaaagtat tcattgaaag tgaccaaaat agttaaagcc
     2101 aaaaccaaca aaaaaaagaa agaaagaaag aaagagagaa aagaaaagaa aagaaaagaa
     2161 aagaaaagaa aagaaaaaaa agaaaagaaa agaaaagaaa aaaagaagaa gaaagaaaaa
     2221 aaaagaaagc gacccacaaa taacaaattt ggtgtagtct attaatgttg tgcattataa
     2281 aggatgcacc tctatgtttg agcagtttct tggttatctt ttatcctcag cttgatatat
     2341 cctgggacat ctgaaaagag ctgcttgcac cacactagct tgcaggcata ttgtggcact
     2401 tttatcctgg attcctgact gttgtcgtat gacacagtca actgtgagtg cttccatccc
     2461 tacgcaggta gtcttggcct atatatgaaa tcttgctgtg catgtgccaa tgaatgaacc
     2521 agcaagcaga attactccat gattcctacc cagtttcctg ccttgacttt tctgccctga
     2581 gtttcctccc tgatggatta tgatctctaa gtgtaagtca aataaacata ttcccctc
//
