LOCUS       NM_133871               2860 bp    mRNA    linear   ROD 06-NOV-2024
DEFINITION  Mus musculus interferon-induced protein 44 (Ifi44), transcript
            variant 1, mRNA.
ACCESSION   NM_133871
VERSION     NM_133871.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2860)
  AUTHORS   Nedomova,M., Haberecht-Muller,S., Moller,S., Venz,S.,
            Prochazkova,M., Prochazka,J., Sedlak,F., Chawengsaksophak,K.,
            Hammer,E., Kasparek,P., Adamek,M., Sedlacek,R., Konvalinka,J.,
            Kruger,E. and Grantz Saskova,K.
  TITLE     DDI2 protease controls embryonic development and inflammation via
            TCF11/NRF1
  JOURNAL   iScience 27 (10), 110893 (2024)
   PUBMED   39328932
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2860)
  AUTHORS   Imai,T., Lin,J., Kaya,G.G., Ju,E., Kondylis,V., Kelepouras,K.,
            Liccardi,G., Kim,C. and Pasparakis,M.
  TITLE     The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death
            and inflammation
  JOURNAL   Immunity 57 (7), 1497-1513 (2024)
   PUBMED   38744293
REFERENCE   3  (bases 1 to 2860)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 2860)
  AUTHORS   de Reuver,R., Verdonck,S., Dierick,E., Nemegeer,J., Hessmann,E.,
            Ahmad,S., Jans,M., Blancke,G., Van Nieuwerburgh,F., Botzki,A.,
            Vereecke,L., van Loo,G., Declercq,W., Hur,S., Vandenabeele,P. and
            Maelfait,J.
  TITLE     ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1
            activation
  JOURNAL   Nature 607 (7920), 784-789 (2022)
   PUBMED   35859175
REFERENCE   5  (bases 1 to 2860)
  AUTHORS   de Reuver,R., Dierick,E., Wiernicki,B., Staes,K., Seys,L., De
            Meester,E., Muyldermans,T., Botzki,A., Lambrecht,B.N., Van
            Nieuwerburgh,F., Vandenabeele,P. and Maelfait,J.
  TITLE     ADAR1 interaction with Z-RNA promotes editing of endogenous
            double-stranded RNA and prevents MDA5-dependent immune activation
  JOURNAL   Cell Rep 36 (6), 109500 (2021)
   PUBMED   34380029
REFERENCE   6  (bases 1 to 2860)
  AUTHORS   Busse,D.C., Habgood-Coote,D., Clare,S., Brandt,C., Bassano,I.,
            Kaforou,M., Herberg,J., Levin,M., Eleouet,J.F., Kellam,P. and
            Tregoning,J.S.
  TITLE     Interferon-Induced Protein 44 and Interferon-Induced Protein
            44-Like Restrict Replication of Respiratory Syncytial Virus
  JOURNAL   J Virol 94 (18), e00297-20 (2020)
   PUBMED   32611756
  REMARK    GeneRIF: Interferon-Induced Protein 44 and Interferon-Induced
            Protein 44-Like Restrict Replication of Respiratory Syncytial
            Virus.
            Publication Status: Online-Only
REFERENCE   7  (bases 1 to 2860)
  AUTHORS   Heraud-Farlow,J.E., Chalk,A.M., Linder,S.E., Li,Q., Taylor,S.,
            White,J.M., Pang,L., Liddicoat,B.J., Gupte,A., Li,J.B. and
            Walkley,C.R.
  TITLE     Protein recoding by ADAR1-mediated RNA editing is not essential for
            normal development and homeostasis
  JOURNAL   Genome Biol 18 (1), 166 (2017)
   PUBMED   28874170
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 2860)
  AUTHORS   Dickinson,M.E., Flenniken,A.M., Ji,X., Teboul,L., Wong,M.D.,
            White,J.K., Meehan,T.F., Weninger,W.J., Westerberg,H., Adissu,H.,
            Baker,C.N., Bower,L., Brown,J.M., Caddle,L.B., Chiani,F., Clary,D.,
            Cleak,J., Daly,M.J., Denegre,J.M., Doe,B., Dolan,M.E., Edie,S.M.,
            Fuchs,H., Gailus-Durner,V., Galli,A., Gambadoro,A., Gallegos,J.,
            Guo,S., Horner,N.R., Hsu,C.W., Johnson,S.J., Kalaga,S., Keith,L.C.,
            Lanoue,L., Lawson,T.N., Lek,M., Mark,M., Marschall,S., Mason,J.,
            McElwee,M.L., Newbigging,S., Nutter,L.M., Peterson,K.A.,
            Ramirez-Solis,R., Rowland,D.J., Ryder,E., Samocha,K.E.,
            Seavitt,J.R., Selloum,M., Szoke-Kovacs,Z., Tamura,M., Trainor,A.G.,
            Tudose,I., Wakana,S., Warren,J., Wendling,O., West,D.B., Wong,L.,
            Yoshiki,A., MacArthur,D.G., Tocchini-Valentini,G.P., Gao,X.,
            Flicek,P., Bradley,A., Skarnes,W.C., Justice,M.J., Parkinson,H.E.,
            Moore,M., Wells,S., Braun,R.E., Svenson,K.L., de Angelis,M.H.,
            Herault,Y., Mohun,T., Mallon,A.M., Henkelman,R.M., Brown,S.D.,
            Adams,D.J., Lloyd,K.C., McKerlie,C., Beaudet,A.L., Bucan,M. and
            Murray,S.A.
  CONSRTM   International Mouse Phenotyping Consortium; Jackson Laboratory;
            Infrastructure Nationale PHENOMIN, Institut Clinique de la Souris
            (ICS); Charles River Laboratories; MRC Harwell; Toronto Centre for
            Phenogenomics; Wellcome Trust Sanger Institute; RIKEN BioResource
            Center
  TITLE     High-throughput discovery of novel developmental phenotypes
  JOURNAL   Nature 537 (7621), 508-514 (2016)
   PUBMED   27626380
  REMARK    Erratum:[Nature. 2017 Nov 16;551(7680):398. doi:
            10.1038/nature24643. PMID: 29144450]
REFERENCE   9  (bases 1 to 2860)
  AUTHORS   Archambaud,C., Nahori,M.A., Soubigou,G., Becavin,C., Laval,L.,
            Lechat,P., Smokvina,T., Langella,P., Lecuit,M. and Cossart,P.
  TITLE     Impact of lactobacilli on orally acquired listeriosis
  JOURNAL   Proc Natl Acad Sci U S A 109 (41), 16684-16689 (2012)
   PUBMED   23012479
REFERENCE   10 (bases 1 to 2860)
  AUTHORS   Aly,M., Wiltshire,S., Chahrour,G., Osti,J.C. and Vidal,S.M.
  TITLE     Complex genetic control of host susceptibility to coxsackievirus
            B3-induced myocarditis
  JOURNAL   Genes Immun 8 (3), 193-204 (2007)
   PUBMED   17287827
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC135237.6 and AC121969.3.
            
            On Jun 1, 2019 this sequence version replaced NM_133871.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK136553.1, AK079749.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-75                AC135237.6         140289-140363       c
            76-575              AC135237.6         139598-140097       c
            576-612             AC135237.6         138071-138107       c
            613-808             AC135237.6         136246-136441       c
            809-955             AC135237.6         135944-136090       c
            956-1127            AC135237.6         129773-129944       c
            1128-1228           AC135237.6         128676-128776       c
            1229-1704           AC135237.6         122531-123006       c
            1705-2860           AC121969.3         144790-145945       c
FEATURES             Location/Qualifiers
     source          1..2860
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 76.91 cM"
     gene            1..2860
                     /gene="Ifi44"
                     /gene_synonym="A430056A10Rik; MTAP44; p44"
                     /note="interferon-induced protein 44"
                     /db_xref="GeneID:99899"
                     /db_xref="MGI:MGI:2443016"
     exon            1..75
                     /gene="Ifi44"
                     /gene_synonym="A430056A10Rik; MTAP44; p44"
                     /inference="alignment:Splign:2.1.0"
     exon            76..575
                     /gene="Ifi44"
                     /gene_synonym="A430056A10Rik; MTAP44; p44"
                     /inference="alignment:Splign:2.1.0"
     exon            576..612
                     /gene="Ifi44"
                     /gene_synonym="A430056A10Rik; MTAP44; p44"
                     /inference="alignment:Splign:2.1.0"
     exon            613..808
                     /gene="Ifi44"
                     /gene_synonym="A430056A10Rik; MTAP44; p44"
                     /inference="alignment:Splign:2.1.0"
     exon            809..955
                     /gene="Ifi44"
                     /gene_synonym="A430056A10Rik; MTAP44; p44"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1127
                     /gene="Ifi44"
                     /gene_synonym="A430056A10Rik; MTAP44; p44"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..1228
                     /gene="Ifi44"
                     /gene_synonym="A430056A10Rik; MTAP44; p44"
                     /inference="alignment:Splign:2.1.0"
     exon            1229..2860
                     /gene="Ifi44"
                     /gene_synonym="A430056A10Rik; MTAP44; p44"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2831..2836
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ifi44"
                     /gene_synonym="A430056A10Rik; MTAP44; p44"
                     /note="hexamer: AATAAA"
     polyA_site      2860
                     /gene="Ifi44"
                     /gene_synonym="A430056A10Rik; MTAP44; p44"
                     /note="major polyA site"
ORIGIN      
        1 attttctaca ggcttggtca ctgagacaga agctgccctc ctcggtgcca gcctcggtac
       61 agactcttca cacagacttc cgtgtttaaa gaggactgtg ctctttaaga gggcttttcc
      121 actagactga agtatggcca tgagaactcg tttgacatgg cagcaagaaa agtgcctgca
      181 gaattatttt ggaggaaaac gtttttgtct tctttacaag gcgagtgtgc agaagttttc
      241 tcatcagaat ttgctctgca catgtgagaa tcaaggtcct accatgatag tggtttacag
      301 tgaaaagtgt gttattggca tgtacctgaa agagggcttc cagggaaaag atgtttctat
      361 caccattttt gcactccaag agactggatt ttcactatgt gcaaaaggac cagattcacc
      421 atatttattg ttccataaaa gaaaaactaa tgatttctct atactattag atgagaaagc
      481 tgtgattgta agttcagcaa tctgtaaaat gctccaactg actgctcgca ataatgtcat
      541 acctattcag gagtgtgaag cttttcgatg tgaagagttg ttggatgaaa gaaagacaag
      601 aggcattgct gtgttacata gtaatttact gcaggccctg agagactaca agccctatgg
      661 agacctggtt cagcaaacac gagttctgct gctgggtcct attggagctg ggaagtctag
      721 ctttgtgaac tcagtcaagt ctgtgttcaa gggcagcatc acacaccaga tcttggtggg
      781 ctgtgatgaa gatggaatct ctgacaagta caggacatat tccatcaagg ccaaggatga
      841 cagtgacccc ctgccattta ttctgtgtga ctcactgggg ctgggtgaga atgccggctt
      901 gcacacagat gatgtatggc acatcttaaa gggccacact cctgacagat accagttcga
      961 ttccatgaaa ccaatcacat caaaccatcc gaactatacc catgacccac tgctgaagga
     1021 cagaattcac tgtgtggttt ttgtgtttga tatcaattct tttgaaatgc actcttctga
     1081 gctggtggca aagatcaaga aaattcgaag agacttgata aaacatggca ttctgcattt
     1141 ggctttactt acacacgtgg atagcctgga tctgattaca aaagaagaca tgacagacat
     1201 atacaactat agtcctgtga agtccaagct ggaggcattc catggagtct ttggttttgc
     1261 cttatctgac atcttggtgg tgagtaatta tgtctcagag tggcagctgg accccgtgaa
     1321 ggacatgctg atcctctcgg cactgaagga gatcctgtat actgcaaatg aattcttgga
     1381 ggatttgcct ttgaacaaat aagtagagtg attatctcgg agcttgacgg tatcatcaac
     1441 ttggccaatt cttgtctggg tctgttgatt acctgctagg tctgtttctt tagcctgttg
     1501 gcatgtgagt agccctgacc tttaacccac tggttgaatg tattttcctc tgtttatttc
     1561 cttcctgata tcttcctcaa atcagtcttg gaagatccgt ataacttcac tcttgtttta
     1621 aaaaagaaaa ttatgaaatg atttatatcc tttgtccatt tcttttaaac tggaatgctt
     1681 tgcttgagac ctagaactgt gttggatcaa tactgactct cattagatat gatcttatag
     1741 gatccatacc ctccctagga ccaaatatat ctgatgtgat acatacatac acaaaatata
     1801 ttatgtatgt aatatattat gcatataata tacagttcaa aattcatata tatagtttat
     1861 atgattgtct aaatatctag gaaccaaaaa tgaggaaaaa tattgttttt tcagatcagc
     1921 ctaacttgct taatagatta tttttagttg catacactta cttgggcaaa acctaacttt
     1981 ttactttgta gctggaagaa gttccatcat gtgtagacag tgcgttttct ggattcattc
     2041 ctccatcatc atatacctag ttagcatcca tccttagcta ttgtacatag tgacacacac
     2101 acacacacac acacacacac acacacacac actcacacac aaatgtaaaa gtattttgtg
     2161 atacttttag cttcactttt gtctccctca cccccgacct catttatttc tgcttcattt
     2221 agtgtagttc ctcctaggta gatatttatc acctctgatt atagactcac tatgttttta
     2281 agtatgttct attatcaacc tgtgcatatg ctgcattgtc accattagag agtaaatatt
     2341 ttgatttact tcattcaaat cttattccat ccctttagag tgctatatta tgttcattta
     2401 ctgctaattc tgaaaggact gggaatggac ttctcatctg actaacttgc agtctgactc
     2461 catatcctga gttttgccag ttctctttct tatggcgtgc agggttctag acaagatgag
     2521 cttagttctg cttgcttctc actaaaaacc cactgagaac gttttatctt ttcttagata
     2581 tcagaagaaa aatgttacaa tgttgcaaaa aaagaaagga agaaaaggag agactttatc
     2641 atatgttaac aatgaattca ttaagagagt agtgagagaa cagggaatga agaaggcaca
     2701 gagactgtgc caggggaaaa gcacacaaac aagattacag tgctcttgat aaaaagatga
     2761 acaagataaa agtaatcagc tacaaggacc aatcgcaatt ctgttggatt tatattctgt
     2821 atctatgaaa aataaaatag ttaactgttt aaaacccaaa
//
