LOCUS       NM_145449               1093 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus interferon, alpha-inducible protein 27 like 2B
            (Ifi27l2b), mRNA.
ACCESSION   NM_145449
VERSION     NM_145449.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1093)
  AUTHORS   Lu,M.Y. and Liao,F.
  TITLE     Interferon-stimulated gene ISG12b2 is localized to the inner
            mitochondrial membrane and mediates virus-induced cell death
  JOURNAL   Cell Death Differ 18 (6), 925-936 (2011)
   PUBMED   21151029
  REMARK    GeneRIF: ISG12b2 is a novel IMM protein induced by IFNs and
            regulates mitochondria-mediated apoptosis during viral infection
REFERENCE   2  (bases 1 to 1093)
  AUTHORS   Parker,N. and Porter,A.C.
  TITLE     Identification of a novel gene family that includes the
            interferon-inducible human genes 6-16 and ISG12
  JOURNAL   BMC Genomics 5 (1), 8 (2004)
   PUBMED   14728724
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BN000232.1, AC154347.2 and AK007590.1.
            
            On Dec 17, 2009 this sequence version replaced NM_145449.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC021795.1, BN000232.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-263               BN000232.1         1-263
            264-446             AC154347.2         89443-89625         c
            447-638             BN000232.1         447-638
            639-1093            AK007590.1         530-984
FEATURES             Location/Qualifiers
     source          1..1093
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 52.93 cM"
     gene            1..1093
                     /gene="Ifi27l2b"
                     /gene_synonym="1810023F06Rik; ISG12(b2)"
                     /note="interferon, alpha-inducible protein 27 like 2B"
                     /db_xref="GeneID:217845"
                     /db_xref="MGI:MGI:1916390"
     exon            1..71
                     /gene="Ifi27l2b"
                     /gene_synonym="1810023F06Rik; ISG12(b2)"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..916
                     /gene="Ifi27l2b"
                     /gene_synonym="1810023F06Rik; ISG12(b2)"
                     /note="interferon stimulated gene 12(b2);
                     interferon-stimulated gene 12 protein B2; interferon
                     alpha-inducible protein 27-like protein 2B"
                     /codon_start=1
                     /product="interferon alpha-inducible protein 27-like
                     protein 2B precursor"
                     /protein_id="NP_663424.1"
                     /db_xref="CCDS:CCDS26133.1"
                     /db_xref="GeneID:217845"
                     /db_xref="MGI:MGI:1916390"
                     /translation="MKRKFVGAAIGGALAVAGAPVALSAVGFTGAGIAAGSIAAKMMS
                     AAAIANGGGIAAGGLVATLQSVGVLGLSTITNIILVAVGTATGARAEGSMGASREQES
                     GPQDPPQELQEPQEPPSCKKQDLNLGKFVGAAIGGALAVAGAPIALSAVGFTGAGIAA
                     GSIAAKMMSAAAIANGGGIAAGGLVATLQSVGILGLSTSTNIILGAVGAATGATAAGA
                     MGACREQEPGLQDLQQEPKEPQEPQELQKQQEPQEPQELQKQQETQETQETQELQKTQ
                     EPPSYEK"
     exon            72..101
                     /gene="Ifi27l2b"
                     /gene_synonym="1810023F06Rik; ISG12(b2)"
                     /inference="alignment:Splign:2.1.0"
     exon            102..263
                     /gene="Ifi27l2b"
                     /gene_synonym="1810023F06Rik; ISG12(b2)"
                     /inference="alignment:Splign:2.1.0"
     exon            264..446
                     /gene="Ifi27l2b"
                     /gene_synonym="1810023F06Rik; ISG12(b2)"
                     /inference="alignment:Splign:2.1.0"
     exon            447..476
                     /gene="Ifi27l2b"
                     /gene_synonym="1810023F06Rik; ISG12(b2)"
                     /inference="alignment:Splign:2.1.0"
     exon            477..638
                     /gene="Ifi27l2b"
                     /gene_synonym="1810023F06Rik; ISG12(b2)"
                     /inference="alignment:Splign:2.1.0"
     exon            639..1093
                     /gene="Ifi27l2b"
                     /gene_synonym="1810023F06Rik; ISG12(b2)"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1069..1074
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ifi27l2b"
                     /gene_synonym="1810023F06Rik; ISG12(b2)"
                     /note="hexamer: AATAAA"
     polyA_site      1093
                     /gene="Ifi27l2b"
                     /gene_synonym="1810023F06Rik; ISG12(b2)"
                     /note="major polyA site"
ORIGIN      
        1 cactgtctaa gtaggcactg tgctccctac caggacaact caccggctac caggacaact
       61 catcatgaag agaaaatttg tgggcgctgc tataggagga gctctggctg tggcaggggc
      121 acctgtcgcc ctgagtgccg tgggcttcac tggggcaggc attgcagctg ggtccatagc
      181 agccaagatg atgtctgctg cagcaattgc caatggaggt ggaattgcag caggaggcct
      241 ggtagccaca ctccagtcag tgggggtcct tggactctcc acaataacca acatcatcct
      301 ggtggctgtt gggacagcca caggagctag agctgaagga tccatgggag cctccagaga
      361 gcaggagtca gggcctcagg atcctccgca ggagctgcag gagccacagg agcctccaag
      421 ttgtaagaag caagatttga atttaggaaa atttgtgggc gctgctatag gaggagctct
      481 ggctgtggca ggggcaccta tcgccctgag tgccgtgggc ttcactgggg caggcattgc
      541 agctgggtcc atagcagcca agatgatgtc tgctgcagca attgccaatg gaggtggaat
      601 tgcagcagga ggcctggtag ccacactcca gtcagtgggg atccttggac tctccacatc
      661 aaccaatatc atccttggag ctgttggggc agccacagga gctacagctg caggagccat
      721 gggagcctgc agagagcagg agccaggact gcaggatctt cagcaagagc caaaggagcc
      781 acaggagcca caggagctgc agaagcagca ggagccacag gagcctcagg agctgcagaa
      841 gcagcaggag acacaggaga cacaggagac gcaggaactg cagaagacac aggagcctcc
      901 aagttatgag aagtgatatt tgaatttagg agatgacatc tctaccagtt taactcaaag
      961 cttataagaa ttacccagga gaaaaagtac caagatgcac tggttctttg tacttcagag
     1021 aatgagggta cttcaaaacc ctcactgatg tcagagaata atgaaaaaaa taaagatggt
     1081 ttgttggtgt ggc
//
