LOCUS       NM_001024721            1294 bp    mRNA    linear   ROD 05-AUG-2024
DEFINITION  Mus musculus interferon activated gene 214 (Ifi214), mRNA.
ACCESSION   NM_001024721 XM_619700 XM_899478 XM_899484
VERSION     NM_001024721.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Brunette,R.L., Young,J.M., Whitley,D.G., Brodsky,I.E., Malik,H.S.
            and Stetson,D.B.
  TITLE     Extensive evolutionary and functional diversity among mammalian
            AIM2-like receptors
  JOURNAL   J Exp Med 209 (11), 1969-1983 (2012)
   PUBMED   23045604
REFERENCE   2  (bases 1 to 1294)
  AUTHORS   Cridland,J.A., Curley,E.Z., Wykes,M.N., Schroder,K., Sweet,M.J.,
            Roberts,T.L., Ragan,M.A., Kassahn,K.S. and Stacey,K.J.
  TITLE     The mammalian PYHIN gene family: phylogeny, evolution and
            expression
  JOURNAL   BMC Evol Biol 12, 140 (2012)
   PUBMED   22871040
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC084073.22.
            
            On Nov 15, 2007 this sequence version replaced NM_001024721.1.
            
            Summary: This gene encodes a protein that is a member of the
            PAAD/DAPIN/Pyrin domain family of proteins. However, compared to
            the related pyrin and HIN domain family, member 1 (Pyhin1) protein,
            this protein is C-terminally truncated and lacks a HIN domain,
            which has an unknown function. It is therefore possible that this
            gene represents a pseudogene of the Pyhin1 gene, but it is
            currently being retained as a functional protein-coding gene based
            on the presence of an intact PAAD/DAPIN/Pyrin domain. [provided by
            RefSeq, Jul 2008].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK156095.1, AK171847.1 [ECO:0000332]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-286               AC084073.22        227354-227639       c
            287-568             AC084073.22        220956-221237       c
            569-705             AC084073.22        219524-219660       c
            706-945             AC084073.22        218146-218385       c
            946-1294            AC084073.22        212993-213341       c
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 80.45 cM"
     gene            1..1294
                     /gene="Ifi214"
                     /gene_synonym="p214; Pyhin-B"
                     /note="interferon activated gene 214"
                     /db_xref="GeneID:545384"
                     /db_xref="MGI:MGI:3584522"
     exon            1..286
                     /gene="Ifi214"
                     /gene_synonym="p214; Pyhin-B"
                     /inference="alignment:Splign:2.1.0"
     exon            287..568
                     /gene="Ifi214"
                     /gene_synonym="p214; Pyhin-B"
                     /inference="alignment:Splign:2.1.0"
     CDS             307..966
                     /gene="Ifi214"
                     /gene_synonym="p214; Pyhin-B"
                     /note="interferon-inducible protein 214"
                     /codon_start=1
                     /product="pyrin and HIN domain-containing protein 1-like"
                     /protein_id="NP_001019892.2"
                     /db_xref="CCDS:CCDS35790.2"
                     /db_xref="GeneID:545384"
                     /db_xref="MGI:MGI:3584522"
                     /translation="MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDR
                     VKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKR
                     QRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSG
                     QTSSRSSETLQSIIQSPETPTRSSSRILDPPVSPGTAYSSAQALGVLLATPAKVIKAR
                     N"
     exon            569..705
                     /gene="Ifi214"
                     /gene_synonym="p214; Pyhin-B"
                     /inference="alignment:Splign:2.1.0"
     exon            706..945
                     /gene="Ifi214"
                     /gene_synonym="p214; Pyhin-B"
                     /inference="alignment:Splign:2.1.0"
     exon            946..1294
                     /gene="Ifi214"
                     /gene_synonym="p214; Pyhin-B"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1267..1272
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ifi214"
                     /gene_synonym="p214; Pyhin-B"
                     /note="hexamer: AATAAA"
     polyA_site      1286
                     /gene="Ifi214"
                     /gene_synonym="p214; Pyhin-B"
                     /note="major polyA site"
ORIGIN      
        1 gagacattca gcaagcctca gtccatggag tgagtctaac ctgagaattt ctgtagatta
       61 cattttccag ttcccaagag atttattggt ttatcttctt cacacacaca cacacacaca
      121 cacacacaca cacacacaca cacacacaca ccaactcctc ccagtcccca acaaacttta
      181 agaagaagaa ggacaaaaga gaagaggagg aagaggagtg gagaagcctc tagtcctgcc
      241 ctgtagaaga tctcagcttt acatccttag agaaacatcc agcaaggttc acacgtaatt
      301 tgaaagatgg tgaatgaata caagagaatt gttcttctga caggattaat gggtattaat
      361 gaccatgatt ttagaatggt taagtccttg ttgagcaaag aattaaaact aaataaaatg
      421 caagatgaat acgacagagt taagattgct gatttgatgg aagacaagtt cccaaaagat
      481 gctggagtgg tccaactgat aaaactatat aagcagattc caggacttgg agacattgct
      541 aataaactca aaaatgagaa ggcaaaagct aaaaggaaag ggaaagggaa acggaaaacc
      601 gcagcaaaaa gacaaaggca agaagaaccc agtacttccc aacctatgtc caccacaaat
      661 gaagatgcag aaccagaatc agggaggagt acacctgaca cacaggttgc tcagttatct
      721 ttaccaactg cttcccgaag gaaccaagcc attcaaattt ctccaacaat agcatccagc
      781 agtggtcaga ccagcagcag atcttcagaa acattacaaa gcatcattca gtcccccgaa
      841 actccaacaa gatcatccag caggattctg gaccctccag tgtctccagg aacagcatat
      901 agcagtgccc aggcacttgg agttcttcta gcaacaccag ccaaggtcat caaagctagg
      961 aactgagaaa caaccactca gttctgcttc ctttatgaaa ctgcattaat tcttgttttg
     1021 tggacttgga catcactgat gtttatacag ataagatcct gttccaacta tagaaaaatg
     1081 tcattcaact gataaaagca agctctttgc tttggaaatg gtccttattc tttccacagt
     1141 tttagcattt tattacatat tttgatttta taatgtttat actttgaatg aaaaaaaact
     1201 tcaggtactt cacaagtttc ttgcatttgt cggttgcttt aaaactgggt ctgcagacca
     1261 aggtgcaata aacatgtttc atgaaatatt ttca
//
