LOCUS       NM_001204910            3496 bp    mRNA    linear   ROD 19-AUG-2024
DEFINITION  Mus musculus interferon activated gene 207 (Ifi207), mRNA.
ACCESSION   NM_001204910 XM_001479984 XM_003084474 XM_980696
VERSION     NM_001204910.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3496)
  AUTHORS   Moran,E.A., Salas-Briceno,K., Zhao,W., Enya,T., Aguilera,A.N.,
            Acosta,I., Alonzo,F., Kiani,D., Behnsen,J., Alvarez,C., Keane,T.M.,
            Adams,D.J., Lilue,J. and Ross,S.R.
  TITLE     IFI207, a young and fast-evolving protein, controls retroviral
            replication via the STING pathway
  JOURNAL   mBio 15 (7), e0120924 (2024)
   PUBMED   38860764
  REMARK    GeneRIF: IFI207, a young and fast-evolving protein, controls
            retroviral replication via the STING pathway.
REFERENCE   2  (bases 1 to 3496)
  AUTHORS   Brunette,R.L., Young,J.M., Whitley,D.G., Brodsky,I.E., Malik,H.S.
            and Stetson,D.B.
  TITLE     Extensive evolutionary and functional diversity among mammalian
            AIM2-like receptors
  JOURNAL   J Exp Med 209 (11), 1969-1983 (2012)
   PUBMED   23045604
REFERENCE   3  (bases 1 to 3496)
  AUTHORS   Cridland,J.A., Curley,E.Z., Wykes,M.N., Schroder,K., Sweet,M.J.,
            Roberts,T.L., Ragan,M.A., Kassahn,K.S. and Stacey,K.J.
  TITLE     The mammalian PYHIN gene family: phylogeny, evolution and
            expression
  JOURNAL   BMC Evol Biol 12, 140 (2012)
   PUBMED   22871040
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 3496)
  AUTHORS   Choubey,D., Snoddy,J., Chaturvedi,V., Toniato,E., Opdenakker,G.,
            Thakur,A., Samanta,H., Engel,D.A. and Lengyel,P.
  TITLE     Interferons as gene activators. Indications for repeated gene
            duplication during the evolution of a cluster of
            interferon-activatable genes on murine chromosome 1
  JOURNAL   J Biol Chem 264 (29), 17182-17189 (1989)
   PUBMED   2477366
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ056316.1, AK054438.1, CJ065456.1, AC117682.11, BE634329.1,
            BE335648.1 and BX527645.1.
            
            On or before Mar 16, 2011 this sequence version replaced
            XM_980696.3, XM_003084474.1, XM_001479984.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-358               CJ056316.1         4-361
            359-886             AK054438.1         298-825
            887-922             CJ065456.1         244-279
            923-2318            AC117682.11        25664-27059
            2319-2885           BE634329.1         1-567
            2886-3282           BE335648.1         86-482
            3283-3496           BX527645.1         259-472
FEATURES             Location/Qualifiers
     source          1..3496
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 80.61 cM"
     gene            1..3496
                     /gene="Ifi207"
                     /gene_synonym="Pyhin-A; pyhinA"
                     /note="interferon activated gene 207"
                     /db_xref="GeneID:226691"
                     /db_xref="MGI:MGI:2138302"
     exon            1..222
                     /gene="Ifi207"
                     /gene_synonym="Pyhin-A; pyhinA"
                     /inference="alignment:Splign:2.1.0"
     exon            223..507
                     /gene="Ifi207"
                     /gene_synonym="Pyhin-A; pyhinA"
                     /inference="alignment:Splign:2.1.0"
     CDS             243..3179
                     /gene="Ifi207"
                     /gene_synonym="Pyhin-A; pyhinA"
                     /note="interferon-activatable protein"
                     /codon_start=1
                     /product="uncharacterized protein LOC226691"
                     /protein_id="NP_001191839.1"
                     /db_xref="CCDS:CCDS56659.1"
                     /db_xref="GeneID:226691"
                     /db_xref="MGI:MGI:2138302"
                     /translation="MVKEYKRIVLLKGLECINKHHFSLFKSLLARDLSLERDNQEKYS
                     TIQIANMMEEKFKPDAGLGELIEFCEKVPALRKRAEILKKERSEVTGETSLEKNGQEA
                     GPATPTSTTSHMLTSERGETSATQEETSTAQGETSTAQAGTSTAQAGTSTAQAGTSTA
                     QTKRKQITKSEGEKKKKLTQEQAQLSEPLGTDRKKDEDCLQTPLMAPPTPPSSSSNKK
                     QKNTTIPKHGIIKTRGPQEIHQLVEFSSSSNFPAVSELPTFEGLSAIPSSRLQSSQKP
                     LEAHLDLKMSPSSSRSPCHNLSVSLTSDSNVHLNSNAHSIQSSGAQVPYVPSATGFSN
                     VRVPLMPSKTVSCSSIAPHMSLIKVPSSIQDLHLPTQEAFSSTEDPHNQAIASKNLQT
                     TKMPPTTLTSKAQLLKMPSSATSSSSVQVSHTLATVSRSTSVKQILQTTRSSSIQILN
                     SATVKASKNVQASQVSLPTEPNYFQASVAPPSATPSSSTSLLVPLSKATSRAQSTQIH
                     PERESICVQAHRAPSSTVSRNKCTTQLTQGAASGTGKAFSLPEVKASMKVQAPQVSSP
                     TASMSILNPNATPPTTSSNLLAPHATSSTTYSILLAPYATLSTASSNLLAPQATVSTA
                     SSNLLAPHATLSTTSSNLLAPHATLSTTSSNLLAPHATSSTASSNLLAPQATLSTPSN
                     SLLAPHATLSTTSSNLLAPHATSSTASSNLLAPHATSSTASSNLLAPHATLPTASSNL
                     LAPQLCPVTASRALSAIPVPSATVHSSPSWTPRRGTVPKEPSREEGHHQGPKQVMVLK
                     VTEPFTYDLEEDKRMFHATVATETEFFRVKVFDTALISKFIPRNIIAISDYFGCNGFL
                     EIYRASCVSDVNVNPTMVISNTLRQRANATPKISYLFSQAKGTFVSGEYLVIKKTERN
                     KAIYYGVKDNTGKMEVMVYGRLTNITCEPGNKLRLVCFELNLIEDGLQLKSVRHSYMQ
                     VINARR"
     exon            508..725
                     /gene="Ifi207"
                     /gene_synonym="Pyhin-A; pyhinA"
                     /inference="alignment:Splign:2.1.0"
     exon            726..893
                     /gene="Ifi207"
                     /gene_synonym="Pyhin-A; pyhinA"
                     /inference="alignment:Splign:2.1.0"
     exon            894..2552
                     /gene="Ifi207"
                     /gene_synonym="Pyhin-A; pyhinA"
                     /inference="alignment:Splign:2.1.0"
     exon            2553..2969
                     /gene="Ifi207"
                     /gene_synonym="Pyhin-A; pyhinA"
                     /inference="alignment:Splign:2.1.0"
     exon            2970..3158
                     /gene="Ifi207"
                     /gene_synonym="Pyhin-A; pyhinA"
                     /inference="alignment:Splign:2.1.0"
     exon            3159..3484
                     /gene="Ifi207"
                     /gene_synonym="Pyhin-A; pyhinA"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3460..3465
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ifi207"
                     /gene_synonym="Pyhin-A; pyhinA"
                     /note="hexamer: AATAAA"
     polyA_site      3484
                     /gene="Ifi207"
                     /gene_synonym="Pyhin-A; pyhinA"
                     /note="major polyA site"
ORIGIN      
        1 gtttcagcac tgctcaccca agggagacag cacagagaga tagccaatgc tgctcaaaaa
       61 acaactctga gagtgtccta atcactagtg ccttccttta caccccacgc ttcagtttct
      121 catttactac ctgatctacc tacctactcg agccaagcag gccacttctt gtgttgttga
      181 aggtctcagg atctgtacat cgcagcagaa atatccaagg aggctcacaa acaacttgaa
      241 agatggtgaa agaatataag agaattgttc tgctgaaagg acttgaatgt atcaataagc
      301 atcattttag cttatttaag tcattgctgg ccagagattt aagtctggaa agagacaacc
      361 aagagaaata ctccacaatt cagattgcta acatgatgga agagaaattc aaacccgatg
      421 ctggattggg tgaactgatc gagttttgtg aaaaagtacc agctcttaga aaacgtgctg
      481 aaattcttaa aaaagagaga tcagaagtaa caggagaaac atcactggaa aaaaatggtc
      541 aagaagcagg tcctgcaaca cctacatcaa ctacaagcca catgctaaca tctgaaagag
      601 gagagacttc cgcaacccag gaagagactt ccacagctca gggggagact tccacagctc
      661 aggcggggac ttccacagct caggcgggga cttccacagc tcaggcgggg acttctacag
      721 cccagacaaa gagaaaacaa atcacaaaaa gtgaaggtga aaagaaaaag aagctcaccc
      781 aggagcaggc tcagctttca gaacctttag gaaccgatag aaaaaaagat gaagattgtc
      841 tccagactcc tcttatggca ccaccaacac cacccagcag ttcctcaaac aagaaacaga
      901 aaaacacaac catcccaaaa catggtatca taaagacaag gggtcctcag gaaattcatc
      961 aacttgtaga attttcatca tccagcaact tcccagctgt aagtgaactc ccgacctttg
     1021 aaggactttc agcaattcct tctagcagac ttcagtcttc tcagaagcct ctagaagctc
     1081 acttggattt aaagatgtct ccaagctctt caagatcacc ttgccataat ctttcagtgt
     1141 ctctaacgtc agactcaaat gttcatctga actctaatgc acattccatc cagtccagtg
     1201 gtgcccaggt tccttatgta ccatcagcaa caggattcag taatgtcagg gttcctctta
     1261 tgccttcaaa aacagtgtcc tgctcttcca ttgctcctca catgtcttta ataaaggtac
     1321 ccagcagtat ccaggacctt caccttccta cacaagaagc attcagtagc acagaggatc
     1381 ctcacaatca agcaatagca tccaaaaatc tccaaactac taaaatgcct ccaacaacac
     1441 tgacaagcaa agcccagctc ctaaagatgc cttcttcagc aacatcatcc agcagtgttc
     1501 aggtttctca tactctagca actgtgtcca gaagcacctc tgtcaaacag atacttcaaa
     1561 caacaagatc cagtagcatt cagattctta actctgctac agtaaaagca tccaagaatg
     1621 tccaggcctc tcaagtatct ttaccaacag aacccaatta tttccaggct tctgtggcac
     1681 ctccatcagc aacacccagc agttctacat ctcttctggt acctttgtca aaagccacaa
     1741 gcagagccca gagtactcaa attcatccag aaagagaatc catttgtgtc caggctcatc
     1801 gtgctccttc atcaacagtg tccagaaata agtgcaccac tcagttgaca caaggggcag
     1861 catccggtac tgggaaggcc ttttccctcc ctgaagtaaa agcatccatg aaagtccaag
     1921 cacctcaggt gtcttcccca acagcatcca tgagtatcct gaatccaaat gcaacccccc
     1981 caacaacatc cagcaatctc ctggctccac atgcaacttc atcaacaaca tatagcatcc
     2041 tcctggctcc atatgcaact ctatcaacag catctagcaa cctcctggct ccacaagcaa
     2101 ctgtatcaac agcatctagc aacctcctgg ctccacatgc aactctatca acaacatcta
     2161 gcaacctcct ggctccacat gcaactctat caacaacatc tagcaacctc ctggctccac
     2221 atgcaacttc atcaacagca tctagcaacc tcctggctcc acaagcaact ctatcaacac
     2281 catccaatag tctcctggct ccacatgcaa ctctatcaac aacatctagc aacctcctgg
     2341 ctccacatgc aacttcatca acagcatcta gcaacctcct ggctccacat gcaacttcat
     2401 caacagcatc tagcaacctc ctggctccac atgcaactct accaacagca tccagcaatc
     2461 ttctggctcc acagttgtgt ccagtaacag catctagggc tctcagtgct attccagtgc
     2521 cttcagcaac agtacacagc agtccatcct ggacaccaag gagaggaact gtaccaaagg
     2581 agccttctag ggaagaaggt caccatcaag gtcccaaaca agtgatggtg ctgaaagtaa
     2641 cagaaccatt tacatatgac ctggaagaag ataaaaggat gtttcatgct acagtggcta
     2701 ctgaaactga gttcttcaga gtgaaggttt ttgacacagc tctaataagc aagttcatcc
     2761 caagaaatat cattgccata tcagattatt ttgggtgcaa tggatttttg gagatataca
     2821 gagcttcctg tgtctctgat gtgaacgtta acccaacaat ggtcatctca aatacactga
     2881 gacaaagagc taatgcaact cctaaaattt cttatctttt ctcacaagca aaggggacat
     2941 ttgtgagtgg agagtactta gtaattaaga aaactgagag gaataaagcc atttactatg
     3001 gagttaaaga taatacaggg aaaatggaag tgatggttta tggacgactc accaatatca
     3061 cgtgtgaacc aggcaataaa cttagacttg tctgctttga attgaatctc attgaagatg
     3121 ggttgcagct gaagtctgta aggcacagtt acatgcaggt catcaatgct agaaggtgaa
     3181 ggaaagccac tcaacccaga ctcagtcagg ggaacctctc tggaaccata cttctgaaaa
     3241 cctggatgcc aatgacattt tttgtggaga taagattcaa gtacagaaaa taaaagtgca
     3301 taggcctgtt gaaataccag ctctactaaa agcagctctt aattctaaga aatggggctt
     3361 tcttatatgc tttacacatt ttctattatc aaagttttat atgttgtctc tataacttct
     3421 gtgattgttt aatttgtaat ttttatacct aaaacttaaa ataaattcac acaatttctg
     3481 taaaaaaaaa aaaaaa
//
