LOCUS       NM_010500               3272 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus immediate early response 5 (Ier5), mRNA.
ACCESSION   NM_010500
VERSION     NM_010500.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3272)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 3272)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3272)
  AUTHORS   Lewandowski,J.P., Du,F., Zhang,S., Powell,M.B., Falkenstein,K.N.,
            Ji,H. and Vokes,S.A.
  TITLE     Spatiotemporal regulation of GLI target genes in the mammalian limb
            bud
  JOURNAL   Dev Biol 406 (1), 92-103 (2015)
   PUBMED   26238476
REFERENCE   4  (bases 1 to 3272)
  AUTHORS   Okada,A., Kushima,K., Aoki,Y., Bialer,M. and Fujiwara,M.
  TITLE     Identification of early-responsive genes correlated to valproic
            acid-induced neural tube defects in mice
  JOURNAL   Birth Defects Res A Clin Mol Teratol 73 (4), 229-238 (2005)
   PUBMED   15799026
REFERENCE   5  (bases 1 to 3272)
  AUTHORS   Gottgens,B., Barton,L.M., Chapman,M.A., Sinclair,A.M., Knudsen,B.,
            Grafham,D., Gilbert,J.G., Rogers,J., Bentley,D.R. and Green,A.R.
  TITLE     Transcriptional regulation of the stem cell leukemia gene
            (SCL)--comparative analysis of five vertebrate SCL loci
  JOURNAL   Genome Res 12 (5), 749-759 (2002)
   PUBMED   11997341
REFERENCE   6  (bases 1 to 3272)
  AUTHORS   Hunter,K., Greenwood,J., Yang,Y.L., Cunningham,J.M., Birren,B. and
            Housman,D.
  TITLE     An integrated somatic cell hybrid, YAC, and BAC map of the Rmc1
            region of mouse chromosome 1
  JOURNAL   Genomics 58 (3), 318-322 (1999)
   PUBMED   10373331
REFERENCE   7  (bases 1 to 3272)
  AUTHORS   Williams,M., Lyu,M.S., Yang,Y.L., Lin,E.P., Dunbrack,R., Birren,B.,
            Cunningham,J. and Hunter,K.
  TITLE     Ier5, a novel member of the slow-kinetics immediate-early genes
  JOURNAL   Genomics 55 (3), 327-334 (1999)
   PUBMED   10049588
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ064636.1, BC051986.1, AW913049.1, CX200138.1 and BE200357.1.
            
            On Dec 13, 2007 this sequence version replaced NM_010500.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-26                CJ064636.1         2-27
            27-2116             BC051986.1         1-2090
            2117-2315           AW913049.1         290-488
            2316-2805           CX200138.1         264-753
            2806-3272           BE200357.1         1-467               c
FEATURES             Location/Qualifiers
     source          1..3272
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 66.45 cM"
     gene            1..3272
                     /gene="Ier5"
                     /note="immediate early response 5"
                     /db_xref="GeneID:15939"
                     /db_xref="MGI:MGI:1337072"
     exon            1..3270
                     /gene="Ier5"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2093..2098
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ier5"
                     /note="hexamer: ATTAAA"
     polyA_site      2111
                     /gene="Ier5"
                     /note="major polyA site"
     regulatory      3249..3254
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ier5"
                     /note="hexamer: AATAAA"
     polyA_site      3270
                     /gene="Ier5"
ORIGIN      
        1 gctcagttta gagtccggct cagaacggtt ctgttgtctg aagggaagcg gcggaggggg
       61 actacgcgtc accaggtctt ttctccaccg agctttcaga cgccgagggt acaaccacag
      121 aggaagacct gatcccgcct acagctcctc tcgcagcttc agaaggcaag caggcgttca
      181 ccctatcgtc tggaagcgaa ggcaggatgg agttcaagct ggaggctcac cgcatcgtca
      241 gcatctccct gggcaagatc tacaactcgc gggtccagcg cggcggcatc aagctgcaca
      301 agaacctctt ggtgtcgttg gtgctgcgca gcgcccgcca agtctacctg agtgacccct
      361 gccctggcct ctacctggct ggccctgcgg ggaccccggc ggtgccgccg cctcagcagc
      421 ctggagagcc tgtagccggg ccaccctccg gctggggaga gccgcccccg ccggtcgccc
      481 gtgccgcctg gccggagccc gagcctcagc cgcagcctca gcctcagcgt ccctccgtgt
      541 gccacacgcc cggagcggga agctcagaac cggtggccgc ggtggccgga tcgggggaag
      601 ctctccgggg cggagaggag gactcggcgg cagctgcttg gggccgcgtg gagcgtccgc
      661 gcgcggcgtc ttcaggaggt ggctcggacg cgtgccccga ggggccccgg gcagtgcgcc
      721 gcccgtgcgg ctgtcccccg gccgtggagg agcggtcctc cgaggacggg tcccccgcgc
      781 cacccgcccc gtgtcccagg aagcgtggcg cagcgggagt gggtggcggc cgcgcgagct
      841 gctcggcacc cggctctacc cctctcaaga agccgcgccg gaactcggag gagcagccag
      901 tcaccggcga ggacgacacc gacgaggaga tggagaccgg gaacgtggca aacctcatca
      961 gcatcttcgg gtctagcttc tcgggactcc tacggaaaag ccccgcaggc ggccgagagg
     1021 aagaggaggc ggaggagggc ggcccggaag ccgccgagcc ggggcagatc tgctgcgaca
     1081 agccggtgct gagagacatg agcccctgga gcacagccat cgtggccttc tgagcccccg
     1141 ggacccgagt ggctggagct tgagcagcgg gagtccccga agtgcggccg gggcctctcc
     1201 cggccgcgag gacgagccga gaccgtaggc gctgggcgcg taggggagac tggttgctgc
     1261 cgggcagcac atcgccccag aaggggcagc ccggctgggc cgtggctctc gagtctcatc
     1321 ctgagaccta gagttggagg cttattggaa gaggacgatc gatcgttaac ttttgtatct
     1381 gtgtgtgtcc gtgtgtaagt ttgtcttgtg ttgagactgt tctgtgattc tggaatgcac
     1441 caccccttcc ccggggcttg agactttggg ggtgcagaca gggactttcc tctgccagca
     1501 gcacagaaaa ggaagctgca gaaaggctcg aggaagggga gttccccgtt cgatcttggg
     1561 ggagagaggg actttacaca cacctctctc tcatgaaagc tacgaccgca ccggggcgcg
     1621 gagtggcgtt ttctcacagg atttcctcag actagaggga gttcgtctgg agtagagact
     1681 tgtattattt ttctccctcc ccatcctttc tctggcacag aagaagcgct tctaccctgt
     1741 gattactctg ggaaagcaga acattaaggg accttcaatt ccccacaggg gaaaaaaagc
     1801 ttgctgaact tcacagaaga gttcaagctt ggaaatacgg agtttataga gaaaagatat
     1861 attttttaaa agctctagct cagaacttac tacacagtgc ttttaaaaag tgtttaatga
     1921 aacaaagttt acagacgagc tctaagtgga aggaccttat ggctttgtag ataaggtgac
     1981 tccagtcttt gttgtataaa ggttggggga gctgataagg tttttgtaca gtattttctc
     2041 cttctctgta ttgatttttg tataaaaatg taactttacg tgtctaacac gtattaaata
     2101 ttttgaagca actccactgc ctgtttgtat gtatgtaatc acttgtctgg gtttccaaca
     2161 aggtggcggg gaggggcaac caggctggga aatggaaggt gtggttctta atatcagcca
     2221 ttcacaggcg agggacagtg ttggctgact tgaataagta gcaagaaaga cacgtttaag
     2281 ggtttggttt tggttttttg ttttcacgaa catccccatc catggatact ggtatcaatg
     2341 actgtcagtt tgagacttgc cactacaatt ttctcttcag tcatgacaga ccagtttggt
     2401 tttctatagt ttgatctgat gggaatctct aatattaaat aatattaaaa gccaaatttt
     2461 gcagcctttc caatatcaaa tatttccacc aaaactttgt ttccaaaata ggtctggtaa
     2521 tgtatagatg gtagatcaat ttttagattt gaattggggt gggtgggggt tagatagcag
     2581 cttcagaggt cttactagga ccaaacatga agaaaccgat gaaaccgact tgtctaaatg
     2641 tttagatcca tcactgtggc ccaatatatg tcaaggttga catttgactt tagttgtaga
     2701 aagtaaaaag ctctgaaagt gaaattatgt gtatcaaacc agagaaggaa ggagaccgag
     2761 ggaggttggc taaatttaat tctcatgtag cagaacttcc tgatttgctc ttgtcaccta
     2821 catgatgaca taagtggttt tggtcatgct aaacagatga cagccaaggc aatttaaaga
     2881 gaccgttttg tctaaggcaa aatgttcagt acttaagagg tactctctta ggagcaaacc
     2941 aattagacac ttaagtttta aatataattg ctagtacttg aaaagatgcc accagtttct
     3001 aagaagaatg cttaagaaac agaaatgagg aaagagggaa agggctatat agcctttaga
     3061 caaaaggagc atatgaaata tgctctttgg ccatagctta agctctaatt atatgaacta
     3121 tattagttga ctaggccatt gctttgctct ttctgtaaga tatggctggt tttttaagca
     3181 agggagctgt tacttttcta ctccatcacc ataatcatgt acataataca tagaataata
     3241 atacatagaa taaaacatgc tttaatcaga aa
//
