LOCUS       NM_025409               1404 bp    mRNA    linear   ROD 16-OCT-2024
DEFINITION  Mus musculus immediate early response 3 interacting protein 1
            (Ier3ip1), mRNA.
ACCESSION   NM_025409
VERSION     NM_025409.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1404)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1404)
  AUTHORS   Zhong,X., Moresco,J.J., Keller,K., Lazaro,D.R., Ely,C.,
            Moresco,E.M.Y., Beutler,B. and Choi,J.H.
  TITLE     Essential requirement for IER3IP1 in B cell development
  JOURNAL   Proc Natl Acad Sci U S A 120 (46), e2312810120 (2023)
   PUBMED   37934820
REFERENCE   3  (bases 1 to 1404)
  AUTHORS   Yang,J., Zhen,J., Feng,W., Fan,Z., Ding,L., Yang,X., Huang,Y.,
            Shu,H., Xie,J., Li,X., Qiao,J., Fan,Y., Sun,J., Li,N., Liu,T.,
            Wang,S., Zhang,X., Arvan,P. and Liu,M.
  TITLE     IER3IP1 is critical for maintaining glucose homeostasis through
            regulating the endoplasmic reticulum function and survival of beta
            cells
  JOURNAL   Proc Natl Acad Sci U S A 119 (45), e2204443119 (2022)
   PUBMED   36322741
  REMARK    GeneRIF: IER3IP1 is critical for maintaining glucose homeostasis
            through regulating the endoplasmic reticulum function and survival
            of beta cells.
REFERENCE   4  (bases 1 to 1404)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1404)
  AUTHORS   Wang,B., Harrison,W., Overbeek,P.A. and Zheng,H.
  TITLE     Transposon mutagenesis with coat color genotyping identifies an
            essential role for Skor2 in sonic hedgehog signaling and cerebellum
            development
  JOURNAL   Development 138 (20), 4487-4497 (2011)
   PUBMED   21937600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC132608.2, CX207811.1, AK004281.1, CF951253.1 and BE985081.1.
            
            On Jan 14, 2010 this sequence version replaced NM_025409.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK004281.1, SRR7652917.211966.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                AC132608.2         42758-42768
            12-40               CX207811.1         1-29
            41-525              AK004281.1         26-510
            526-526             CF951253.1         257-257
            527-1385            AK004281.1         511-1369
            1386-1404           BE985081.1         6-24                c
FEATURES             Location/Qualifiers
     source          1..1404
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 51.98 cM"
     gene            1..1404
                     /gene="Ier3ip1"
                     /gene_synonym="1110057H19Rik"
                     /note="immediate early response 3 interacting protein 1"
                     /db_xref="GeneID:66191"
                     /db_xref="MGI:MGI:1913441"
     exon            1..190
                     /gene="Ier3ip1"
                     /gene_synonym="1110057H19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             100..348
                     /gene="Ier3ip1"
                     /gene_synonym="1110057H19Rik"
                     /codon_start=1
                     /product="immediate early response 3-interacting protein
                     1"
                     /protein_id="NP_079685.1"
                     /db_xref="CCDS:CCDS37862.1"
                     /db_xref="GeneID:66191"
                     /db_xref="MGI:MGI:1913441"
                     /translation="MAFTLYSLMQAALLCVNAIAVLHEERFLKNIGWGTDQGIGGFGE
                     EPGIKSQLMNLIRSVRTVMRVPLIIVNSITIVLLLLFG"
     exon            191..292
                     /gene="Ier3ip1"
                     /gene_synonym="1110057H19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            293..1394
                     /gene="Ier3ip1"
                     /gene_synonym="1110057H19Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      484..489
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ier3ip1"
                     /gene_synonym="1110057H19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      506
                     /gene="Ier3ip1"
                     /gene_synonym="1110057H19Rik"
     regulatory      1371..1376
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Ier3ip1"
                     /gene_synonym="1110057H19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1394
                     /gene="Ier3ip1"
                     /gene_synonym="1110057H19Rik"
                     /note="major polyA site"
ORIGIN      
        1 aggcgggctt ccgtagctgg acgcggacgg tggcggcgcc acgtcccggg cggtgtccgg
       61 ggagaagtca gtcgggcctg gggacagttt gaagtaacta tggccttcac gctgtactcc
      121 ctgatgcagg cggccctgct gtgcgtgaac gccatcgccg tgctgcacga ggagcgcttc
      181 ctcaagaaca ttggctgggg aacagaccag ggaatcggtg gatttggaga ggagccagga
      241 attaaatctc aactaatgaa ccttattcgg tctgtaagaa ccgtgatgag agtgccattg
      301 ataatagtaa actcaattac tattgtattg cttctgttat ttggctgaac atcgttggga
      361 aatcagagac tgagaagaag aaaagcccca gaagttactt tctgttgtga ccggaatatt
      421 catgtttcag caggctcatc ttgcagttga caaaaaaaaa aagaaaaaaa aagtaaagtt
      481 gacaataaaa ccagagtttc tatctatctg attttttttt ttttttaatt gtagttgcac
      541 ttgtagatca gattatcaga ggcaggagca ctcccggatt ggagcatact tgttttagct
      601 aaaataggta aaggctagga aagggcacaa aactgctgcc tttgtgtcac tccatacgac
      661 accctgttac agctcaggga tggatttaga tataatctga gagtatataa cttcctatat
      721 aaacttaaga gtttttttaa agtaacagtt acatctagtt gacaaattgg tatttgggta
      781 atttattttg aactctttgg ttacctcgtt tctgctataa agaaatttgt aggtaactct
      841 acggggcaat gccgtgattt cagagagaat tctaattctg gaaaccagtt gtttgggaac
      901 tgtggttttt acgatattat ttattagttg acctgaacag tgagagcaga ctgcttacat
      961 attttccttt gtaggaagtc ttgcctgttt tacaaggatt tgttttataa aaatcagtgt
     1021 aactgttagt tggcaaaatc agcccataca gtcagactag cctgctcccg tgactgtctg
     1081 ttaggaagcc tttgccttcc ttaggttgtg cttccattcc tcggcggagt ggcatgctgt
     1141 aggtatgatt cttaattctg tctgtaggta ggttgttgat tctaagtagc tttcgtttgt
     1201 tcgtctgtct tatgtcttag accagctttg tggtgttctt ggctcatctc ataatactgt
     1261 tgttcagttt atatcagaag agttaaactg tgcaaatatt gtatgaaatg tttcagttac
     1321 cataatttaa aggggtggga tggcatcttt ctgtatagaa aacttttata aataaagttg
     1381 acttttcata ttaaaaaaaa aaaa
//
