LOCUS       NM_177351               5103 bp    mRNA    linear   ROD 02-JUN-2024
DEFINITION  Mus musculus hydroxylysine kinase 1 (Hykk), mRNA.
ACCESSION   NM_177351
VERSION     NM_177351.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5103)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK162425.1 and AC161264.2.
            
            On Mar 28, 2008 this sequence version replaced NM_177351.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK138851.1, AK162425.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2410              AK162425.1         2-2411
            2411-5103           AC161264.2         74043-76735         c
FEATURES             Location/Qualifiers
     source          1..5103
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 29.84 cM"
     gene            1..5103
                     /gene="Hykk"
                     /gene_synonym="Agphd1; C630028N24Rik"
                     /note="hydroxylysine kinase 1"
                     /db_xref="GeneID:235386"
                     /db_xref="MGI:MGI:2443139"
     exon            1..569
                     /gene="Hykk"
                     /gene_synonym="Agphd1; C630028N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            570..920
                     /gene="Hykk"
                     /gene_synonym="Agphd1; C630028N24Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             575..1705
                     /gene="Hykk"
                     /gene_synonym="Agphd1; C630028N24Rik"
                     /EC_number="2.7.1.81"
                     /note="aminoglycoside phosphotransferase domain-containing
                     protein 1; 5-hydroxy-L-lysine kinase; aminoglycoside
                     phosphotransferase domain containing 1"
                     /codon_start=1
                     /product="hydroxylysine kinase"
                     /protein_id="NP_796325.2"
                     /db_xref="CCDS:CCDS23197.1"
                     /db_xref="GeneID:235386"
                     /db_xref="MGI:MGI:2443139"
                     /translation="MSSGAGWQSQASAKPVFTEAQASALVESVFGFKVSKIQPLPSYE
                     DQNFRVHIARGKETTDDPVEYVLKISNTESSQTPELIEMQNHVIMFLRAAGFPTASVC
                     RTKGDNTISLISIDSGSGVKSYLVRMLTYLPGRPIAEVAISHQQLYEIGRLAAQLDKA
                     LEEFHHPKLSLFHRENFIWNLKNVPLLEKYMGALSQSRNREIVEQVIRMFKEEVMTKL
                     SHFRECINHGDLNDHNILVDLSKSASGEGVHQVSGILDFGDMSYGYYVFEVAIVIMYM
                     MIESTNPIQVGGHILAGFESVIPLTAVERQALFLLVCSRFSQSLVMAAYSCQLYPENK
                     EYLMITAKTGWKHLQQLFDMGQKAVEEIWFETAKSYESEISM"
     exon            921..1060
                     /gene="Hykk"
                     /gene_synonym="Agphd1; C630028N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1061..1244
                     /gene="Hykk"
                     /gene_synonym="Agphd1; C630028N24Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1245..5103
                     /gene="Hykk"
                     /gene_synonym="Agphd1; C630028N24Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5073..5078
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hykk"
                     /gene_synonym="Agphd1; C630028N24Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      5098
                     /gene="Hykk"
                     /gene_synonym="Agphd1; C630028N24Rik"
                     /note="major polyA site"
ORIGIN      
        1 agctgactga ggggagagag caatcggcct caggacgtcc ggtcgctgtg cgtgagagga
       61 ggtggaagag actgaagcga gtcaagggtc tctctgaggg gacatccccg agaagcggcg
      121 gcgggctcct gcaacccttg cgctcctcaa actcactgcg tgctgacgcg gcaggtcact
      181 gcccagcccc agccctgctg agatttcagt gcgcagtttt gagggtccca ccctccgcgg
      241 gcctgcatgg tttgggggtg gaagccatcc taaggctcct ctggacctga gacaggccgg
      301 gaacgggttg tgggccacct ccctcccatc ggcgtctttc gctcctcagc aagaccccct
      361 ggaagtgagt cttgcttcca atcgcccttg gagtgtagag ttcctgcagc ccgtgagctg
      421 tgagtggagg caactcacga aataagtgca gggaacatca ctgcctgctt cccaagcctg
      481 gaagctcaca gcagaggggt cgtcgaagac agacgtggag aaagtgctaa ggcagaagtc
      541 acaaagactt tgtaacactt taggagaaga cataatgtca agtggagctg gctggcagtc
      601 acaggcttct gccaagcccg tttttactga ggcacaagcc tctgcactgg tagaatcggt
      661 atttgggttc aaagtttcca agatccagcc actccctagc tatgaggacc aaaactttcg
      721 tgttcacatt gcaagaggca aagagactac agatgaccca gttgaatatg tcctcaaaat
      781 aagcaatacg gagtctagcc aaactccaga gctgattgaa atgcagaacc atgtcatcat
      841 gttcctgaga gcagctggat tcccaacagc ctccgtatgc cgaactaaag gggacaacac
      901 catctctctc atatccattg acagtggatc tggagtcaaa agctacttgg taagaatgct
      961 cacttacctc ccaggaagac caatagctga ggttgccatc agccaccagc aattatatga
     1021 aataggaagg ctggctgccc aattggataa agccctagag gaattccatc atccaaagtt
     1081 aagtcttttt catcgggaga acttcatctg gaatctgaaa aatgttcctc ttctagagaa
     1141 atacatgggt gccctgagcc aaagtcgaaa ccgggagatt gttgaacagg tcattcggat
     1201 gttcaaggaa gaagtaatga ccaaattaag tcattttcga gaatgtatta atcatggtga
     1261 tcttaatgac cataacattt tagtagacct cagcaagtca gcctctggag aaggtgtgca
     1321 tcaagtgtct gggattttag acttcggtga catgagctat ggctactatg tgtttgaagt
     1381 ggcaatcgtt atcatgtaca tgatgattga aagcacaaac cctatacaag taggaggtca
     1441 catcctcgca gggtttgaaa gtgtgatccc cctgacggct gtagagaggc aggctttgtt
     1501 tttacttgta tgcagtcgtt ttagccagtc tctcgtcatg gctgcatact cctgccagct
     1561 gtacccagag aacaaagagt acctcatgat tacagccaaa accggatgga agcatttaca
     1621 gcagctgttc gacatgggcc agaaagccgt tgaagaaatc tggtttgaaa ctgccaagtc
     1681 ctatgaatct gagatatcca tgtgactgcc gcggtaaaaa aattaaatcg ctcaaaactc
     1741 cccggtggtg cacatgcgct cggcgctatg cacccacaat gttctggatt cccgagtgaa
     1801 agacacacac gcacaacctt atttttaata tgccctaagc aggtcaattg ccgggccact
     1861 ccctaactcc acttggttaa cgcacactcc acttcaatat tcctgagtta ttacttacta
     1921 aaatctatat attatctttg tgccctggac ctggctgggc agccctcctg ggcagctttc
     1981 cccctgcacc tacatgtcgg cggtctttcc cttctgtatc tttctggcgt ggtcctatgc
     2041 ccctcttgtg gcaaaatctt ctcttcctac tctctctgtc tcttcccagg aatcctaaaa
     2101 gtcccacctc tgtctctgcc cagtcattgg ccgctggtaa ttttattgac aagtcaaaaa
     2161 ctaactgggg acaggcttcc tttagtccta aatgtgggac actgcaaaca ggtatttttg
     2221 gtaacataat tagcatgaga acacaagccg ttacaagtga ccttagaaaa gcttgtgtta
     2281 attaaaaccc agttggccta gaacaaattt atgaaggatt tttgtgcaga gttaaaactg
     2341 aaatggtaaa acagatccat tctcacaggg cagtggtggc gcacgccttt aatcccagcg
     2401 cttgagaggc agaggcaggc ggatttctga gttcgaggcc agcctggtct acagagtgag
     2461 ttccaggaca gccagggcta tacaaagaaa ccgtgtctcg aaaaacaaaa caaaaaaaca
     2521 aaacagagcc attctaaata ggaattggtg aaggaagatc taatttttac agcgatcttt
     2581 ggaccatctt ttactcttaa gaaagtctac atgatgaacc cttgcctagt atgcaaagcc
     2641 cgggttcaac ctcagcacta cagaaacaag gaaatccaca caagtaccac ccaagtaagc
     2701 atgtctctgt gcaggtcatg cttgcctttt acaagaaaca cacatgatga tacatgactt
     2761 gtcttcagtc tccgaagatc gattctcgtc cttagatcaa tgatttttaa actttgaaaa
     2821 gaatgcatat gtacagctat attaattttg tttgtttgtt tgtttgtttt tgaggcaggg
     2881 tttcttggct gccctggaac tctcaaattc atagagatcc aattgcctct gcctctcaaa
     2941 tgctggaatt aaaggcatct accaccgcac acatattcac atattttgaa taatccacat
     3001 attttaaata cctaacctat acatcgctaa ctctatgaat tcttccttaa tctcacctgt
     3061 caagaagtga ggtagtgagg tctttctgtc tttttttttt ttggcatttt actattacct
     3121 gcatattgtt gtacagtcat ctatcttgta agttaccatg acacagacca tgagaaactt
     3181 aaatacatag cttacacatc acaaattctg tagactctta atctcacctc tctagaagtg
     3241 aggcattcta tcttttttgt ggcatttcac tcttacctgc tgatggttgt acagttatct
     3301 atcctgtaaa ttgacatggc acagccatga aaaacttaca tctgggtgtc tcttcttgtc
     3361 cctctgatag tgccttcccc acagaaaagt ctttggacac atttacaaaa tgaatgcatg
     3421 caagaagaaa gatatggtga agccctcggg gaaaacacaa gagggagtcc tgagaaaaac
     3481 ttgtttggga gagtagctgc aaccagaact ccagacacaa gtgcattgaa gcacatgtag
     3541 gcatccaggc aaggccatta tccaggacac cagcaaggcg cctcagcagt tagggcttac
     3601 tatgctcttc aggctggtct taaacatcgt ggctcccaag atcctcctgt tcagcctccc
     3661 aatgcagaga ctatagtgat acaccattct gtttggcccc acatgttctt tgttctctat
     3721 aactaatgat tgccttttta taagattctg taaaaatgca gatcattgca ttgcatactt
     3781 ggcttaagtt ttatctcagt atttccttta ctggctcctt ttcatgtctc tctagtctaa
     3841 gtggctattt acttattctt gtagggtggg attttttttt ttttcttttc tgttttgaga
     3901 ctggattcca ctgtgttgtc catactggaa tcaagctgtc gcatggttat cctggactca
     3961 catgataatc ctgcccatgc aacccagtag ctgggactgt aggcatgcat agaccactca
     4021 ctgcattctt ttgtttaacc acatgctttc taaagatgac tcaggtctag acccctagtc
     4081 atttatttaa acatcttgtt agtagttatc cgtctatgtg agtaggcttt gatactataa
     4141 ctcttgtctg atgtttgcct gcctatctac ctgtctaaac ttcccaaact aggtatttct
     4201 ctgaatttac ttatacaatt tatttttaac ttctccatgt ctcccttttc ttttcctttc
     4261 tcgtttcttt tcttttcttt ttttagagca agataatgtt tgtacttaga gagtcaattg
     4321 tgagggtttt ttaagaggct atggcagcct cttagcatag actctggcac atagtagagg
     4381 cataataaat agttactaaa taatggatca tatttcaggt tacgcacact caaaatattg
     4441 gtgtggcacg ctgcttgccc ttctcacagt cagccatcga gccctgctgc tttcacaaat
     4501 caggatttta ggttaacaaa tctggagcgg ttttgtcttt cctgcttcat tagtttttca
     4561 gtagaatata ctatactaca atgattattg aatgttattt tacatgcact acctcattta
     4621 atccagaaca gaatcacaaa gatattctga tgattaatct ccatttttaa ataaagaaat
     4681 agagccttga aaagctgatt tattgcttta gaagggagct caggcttaga tcttgaatta
     4741 ggtctttggg ctgttacccc tgttcctaat cactacaaaa tcccatcctg ctgcctttcc
     4801 ttccttgttt ttacacaccc acacccacac ccacacacat gggggcagta catgagatca
     4861 ttcacatgtg aaacacttag gatactcata tttgaggttt ttatttaact tggccaatca
     4921 ggaccagaaa aatgggctgg aacttgggtc tcattccaaa tcagtgttta tcctgttata
     4981 caatggaact ctgcaagttt ctcttgattg ttcttgctaa gagagattct ccactaaatt
     5041 cctattgcaa atattgctaa tttctgtttg aaattaaata tatgctgcat tgtatggata
     5101 ttt
//
