LOCUS       NM_010483               2019 bp    mRNA    linear   ROD 04-OCT-2024
DEFINITION  Mus musculus 5-hydroxytryptamine (serotonin) receptor 5B (Htr5b),
            mRNA.
ACCESSION   NM_010483
VERSION     NM_010483.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2019)
  AUTHORS   Katada,Y., Kunimi,H., Serizawa,N., Lee,D., Kobayashi,K.,
            Negishi,K., Okano,H., Tanaka,K.F., Tsubota,K. and Kurihara,T.
  TITLE     Starburst amacrine cells amplify optogenetic visual restoration
            through gap junctions
  JOURNAL   Mol Ther Methods Clin Dev 30, 1-13 (2023)
   PUBMED   37324975
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2019)
  AUTHORS   Kosugi,K., Yoshida,K., Suzuki,T., Kobayashi,K., Yoshida,K.,
            Mimura,M. and Tanaka,K.F.
  TITLE     Activation of ventral CA1 hippocampal neurons projecting to the
            lateral septum during feeding
  JOURNAL   Hippocampus 31 (3), 294-304 (2021)
   PUBMED   33296119
REFERENCE   3  (bases 1 to 2019)
  AUTHORS   Yoshida,K., Drew,M.R., Mimura,M. and Tanaka,K.F.
  TITLE     Serotonin-mediated inhibition of ventral hippocampus is required
            for sustained goal-directed behavior
  JOURNAL   Nat Neurosci 22 (5), 770-777 (2019)
   PUBMED   30988523
REFERENCE   4  (bases 1 to 2019)
  AUTHORS   Tainaka,K., Murakami,T.C., Susaki,E.A., Shimizu,C., Saito,R.,
            Takahashi,K., Hayashi-Takagi,A., Sekiya,H., Arima,Y., Nojima,S.,
            Ikemura,M., Ushiku,T., Shimizu,Y., Murakami,M., Tanaka,K.F.,
            Iino,M., Kasai,H., Sasaoka,T., Kobayashi,K., Miyazono,K., Morii,E.,
            Isa,T., Fukayama,M., Kakita,A. and Ueda,H.R.
  TITLE     Chemical Landscape for Tissue Clearing Based on Hydrophilic
            Reagents
  JOURNAL   Cell Rep 24 (8), 2196-2210 (2018)
   PUBMED   30134179
REFERENCE   5  (bases 1 to 2019)
  AUTHORS   Vogelgesang,S., Niebert,M., Bischoff,A.M., Hulsmann,S. and
            Manzke,T.
  TITLE     Persistent Expression of Serotonin Receptor 5b Alters Breathing
            Behavior in Male MeCP2 Knockout Mice
  JOURNAL   Front Mol Neurosci 11, 28 (2018)
   PUBMED   29515365
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2019)
  AUTHORS   Burmeister,M., Ren,Q., Makris,G.J., Samson,D. and Bennett,V.
  TITLE     Genes for the neuronal immunoglobulin domain cell adhesion
            molecules neurofascin and Nr-CAM map to mouse chromosomes 1 and 12
            and homologous human chromosomes
  JOURNAL   Mamm Genome 7 (7), 558-559 (1996)
   PUBMED   8672144
REFERENCE   7  (bases 1 to 2019)
  AUTHORS   Uelmen,P.J., Oka,K., Sullivan,M., Chang,C.C., Chang,T.Y. and
            Chan,L.
  TITLE     Tissue-specific expression and cholesterol regulation of
            acylcoenzyme A:cholesterol acyltransferase (ACAT) in mice.
            Molecular cloning of mouse ACAT cDNA, chromosomal localization, and
            regulation of ACAT in vivo and in vitro
  JOURNAL   J Biol Chem 270 (44), 26192-26201 (1995)
   PUBMED   7592824
REFERENCE   8  (bases 1 to 2019)
  AUTHORS   Woodward,E.C. and Monaco,J.J.
  TITLE     Characterization and mapping of the gene encoding mouse proteasome
            subunit DELTA (Lmp19)
  JOURNAL   Immunogenetics 42 (1), 28-34 (1995)
   PUBMED   7797265
REFERENCE   9  (bases 1 to 2019)
  AUTHORS   Danielson,P.E., Watson,J.B., Gerendasy,D.D., Erlander,M.G.,
            Lovenberg,T.W., de Lecea,L., Sutcliffe,J.G. and Frankel,W.N.
  TITLE     Chromosomal mapping of mouse genes expressed selectively within the
            central nervous system
  JOURNAL   Genomics 19 (3), 454-461 (1994)
   PUBMED   7910582
REFERENCE   10 (bases 1 to 2019)
  AUTHORS   Matthes,H., Boschert,U., Amlaiky,N., Grailhe,R., Plassat,J.L.,
            Muscatelli,F., Mattei,M.G. and Hen,R.
  TITLE     Mouse 5-hydroxytryptamine5A and 5-hydroxytryptamine5B receptors
            define a new family of serotonin receptors: cloning, functional
            expression, and chromosomal localization
  JOURNAL   Mol Pharmacol 43 (3), 313-319 (1993)
   PUBMED   8450829
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC111011.6.
            
            On Dec 7, 2007 this sequence version replaced NM_010483.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC115825.1, SRR7345562.3942513.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1053              AC111011.6         93341-94393         c
            1054-2019           AC111011.6         75686-76651         c
FEATURES             Location/Qualifiers
     source          1..2019
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 52.98 cM"
     gene            1..2019
                     /gene="Htr5b"
                     /gene_synonym="5-Ht5b"
                     /note="5-hydroxytryptamine (serotonin) receptor 5B"
                     /db_xref="GeneID:15564"
                     /db_xref="MGI:MGI:96284"
     exon            1..1053
                     /gene="Htr5b"
                     /gene_synonym="5-Ht5b"
                     /inference="alignment:Splign:2.1.0"
     CDS             277..1389
                     /gene="Htr5b"
                     /gene_synonym="5-Ht5b"
                     /note="5-HT-5B; serotonin receptor 5B;
                     protein-tyrosine-phosphatase (EC 3.1.3.48) Ly-5 precursor
                     (B-cell variant)"
                     /codon_start=1
                     /product="5-hydroxytryptamine receptor 5B"
                     /protein_id="NP_034613.2"
                     /db_xref="CCDS:CCDS15239.1"
                     /db_xref="GeneID:15564"
                     /db_xref="MGI:MGI:96284"
                     /translation="MEVSNLSGATPGLAFPPGPESCSDSPSSGRSMGSTPGGLILPGR
                     EPPFSAFTVLVVTLLVLLIVATFLWNLLVLVTILRVRAFHRVPHNLVASTAVSDVLVA
                     ALVMPLSLVSELSVGRRWQLGRSLCHVWISFDVLCCTASIWNVAAIALDRYWTITRHL
                     QYTLRTRSRASALMIAITWALSALIALAPLLFGWGEAYDARLQRCQVSQEPSYAVFST
                     CGAFYLPLAVVLFVYWKIYKAAKFRFGRRRRAVVPLPATTQAKEAPPESEMVFTARRR
                     ATVTFQTSGDSWREQKEKRAAMMVGILIGVFVLCWIPFFLTELISPLCACSLPPIWKS
                     IFLWLGYSNSFFNPLIYTAFNKNYNNAFKSLFTKQR"
     exon            1054..2019
                     /gene="Htr5b"
                     /gene_synonym="5-Ht5b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 caggcaccag tccccaatcc tctgcagtcg gtttgatgcg ctgggcaaag ctggactaag
       61 gagtctcatc tggaaaagag ggtccacgaa aaaggccaaa agaagcgcca aaaggaggct
      121 gcagtttgga aaagggacaa gggtggcgcg gtttggacat ctttttgcgt tgctgggcgc
      181 gcggagtgcc tctcttgctt ctcttgcttc gccacctatc cacagttcat gcaaccacgg
      241 gcacatctcc tgccccagag cccaagtccc tgaataatgg aagtttctaa cctctcaggc
      301 gccactcccg gccttgcctt tcctccggga cccgagagct gcagtgacag cccaagttcc
      361 ggcaggagca tgggatccac cccaggtggg ctcatcttgc ctggccgcga gccgcccttc
      421 tctgctttca ccgtgcttgt ggtgactcta ctggtgttgc tgatcgttgc cactttctta
      481 tggaatctgc tagttctggt gactatcctg cgtgtccgcg ccttccaccg cgtgccacat
      541 aacttggtgg cctcgacagc cgtctcggat gtcctggtgg cggctctggt gatgcctctg
      601 agcctggtga gcgagttgtc cgttgggcga cgttggcagc taggcaggag tctgtgccac
      661 gtgtggatct ccttcgacgt gttgtgctgc accgccagca tctggaacgt ggcggccatc
      721 gccctggatc gctactggac tatcacgcgc cacctgcagt acacgctgcg cacccggagc
      781 cgtgcttctg cgctcatgat cgcgatcacc tgggcactgt ccgcgctcat tgctctcgcc
      841 ccgctgcttt ttggctgggg cgaagcctat gatgctcggc tgcagcgttg ccaggtgagc
      901 caggagccct cctatgctgt cttctccacc tgcggagcct tctacctgcc tctggcggtg
      961 gtgctcttcg tctactggaa aatatacaaa gccgccaaat ttcgattcgg ccgcagacgg
     1021 cgggcggtgg taccgcttcc tgccaccacg caggcaaagg aagcacctcc agagtctgag
     1081 atggtgttca cagcccgtcg ccgagcaaca gtaaccttcc agacaagcgg agactcgtgg
     1141 cgggagcaga aggagaagcg ggcagccatg atggtcggga tcttgattgg cgtgtttgtg
     1201 ctttgttgga tccccttctt cctgacggag ctcatcagcc cgctctgtgc ctgcagcctg
     1261 ccacccatct ggaaaagcat attcctgtgg cttggatatt ccaattcgtt cttcaacccc
     1321 ttgatttaca ctgcctttaa taagaattac aacaatgcct tcaagagcct ctttactaag
     1381 cagagataag aagggctggg gagagaaaag ggaagacctg ggaagagaaa ggggacctgt
     1441 gatcctcatt tcacccgaga ccttctcccc accacccacg gcccgatgat gacactccaa
     1501 aagtcatacc attgggcctg gaacgttgaa gagttctcat ggaggttggc aactgtttgg
     1561 caaacacacc catgccttct acagaaggac gtgacagaca ttattagtga attgtgctcc
     1621 atttctgcac taggcagaaa ccctgccaaa cactttcagg atagatttta ggtattggtg
     1681 agcatttgtt agacctcaca tgtgacaaag ttgatttgct tttccattat ttagtactgt
     1741 gtcctctctc aggagtttcc tgagtctgtc tccttgacac agcctttcct ctatccctta
     1801 tccatcagag gagtttccct ttcttagcct cctatacaac ctccacagga caatgattct
     1861 cagcttagaa gcgggcctca cctgaagctt tgataaaacg tgttccacgc aggtgtcttc
     1921 aagatggctc agtaggtgaa ggcacctgcc cctgagcctg gtggcctgct tttgatggag
     1981 acacacgtaa tggaaggaaa ggaaaaaaaa aaaaaaaaa
//
