LOCUS       NM_175111               4606 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus Hspb associated protein 1 (Hspbap1), transcript
            variant 1, mRNA.
ACCESSION   NM_175111
VERSION     NM_175111.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4606)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4606)
  AUTHORS   Zhang,F., Zhao,X., Jiang,R., Wang,Y., Wang,X., Gu,Y., Xu,L., Ye,J.,
            Chen,C.D., Guo,S., Zhang,D. and Zhao,D.
  TITLE     Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox
            Gene Temporal Collinear Activation for Body Axial Patterning in
            Mice
  JOURNAL   Front Cell Dev Biol 9, 642931 (2021)
   PUBMED   34368113
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4606)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   4  (bases 1 to 4606)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   5  (bases 1 to 4606)
  AUTHORS   Cobellis,G., Nicolaus,G., Iovino,M., Romito,A., Marra,E.,
            Barbarisi,M., Sardiello,M., Di Giorgio,F.P., Iovino,N., Zollo,M.,
            Ballabio,A. and Cortese,R.
  TITLE     Tagging genes with cassette-exchange sites
  JOURNAL   Nucleic Acids Res 33 (4), e44 (2005)
   PUBMED   15741177
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4606)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AA879889.1, AK028824.1, AK076189.1 and AK038142.1.
            
            On Jan 4, 2007 this sequence version replaced NM_175111.2.
            
            Transcript Variant: This variant (1) encodes the functional
            protein.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK089941.1, AK076189.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849376
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-21                AA879889.1         1-21
            22-231              AK028824.1         3-212
            232-659             AK076189.1         199-626
            660-4170            AK028824.1         721-4231
            4171-4606           AK038142.1         2504-2939
FEATURES             Location/Qualifiers
     source          1..4606
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="16"
                     /map="16 25.43 cM"
     gene            1..4606
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /note="Hspb associated protein 1"
                     /db_xref="GeneID:66667"
                     /db_xref="MGI:MGI:1913917"
     exon            1..154
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..1542
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /note="27 KdA heat shock protein-associated protein 1;
                     protein associated with small stress protein 1"
                     /codon_start=1
                     /product="HSPB1-associated protein 1"
                     /protein_id="NP_780320.2"
                     /db_xref="CCDS:CCDS28142.1"
                     /db_xref="GeneID:66667"
                     /db_xref="MGI:MGI:1913917"
                     /translation="MAAGCEGIAPPTLGERTVGEEGEPVKPFTPEKAKEIIMSLQQPA
                     IFCNMVFDWPSRHWTAKHLSKVLEGKQIRFRMGLRGTGTVPQYETECSYVDATLEEFL
                     TWNCDQSSISGPFKDYEHSKFWAYADYKYFVTLFEDKTDVFQEVVWSDFGFPGRNGQE
                     STLWIGSFGAHTPCHLDSYGCNLVFQVQGRKRWHLFPPEDTPFLYPTRIPYEESSVFS
                     KINVVNPDLKCFPQFQKARRHMVTLSPGQVLFVPRHWWHYVESLDPVTVSINSWIELE
                     EDHLARVEEAITRMLVCTLKTAEDPHHPRTWLNPTEVEETSHEVNSCYLNSAVCAFFD
                     HCEKAKAVELQVLSANGAEPRVQEEHMEVEQAQGPSLTSRAEKQEAVSLFGPDLIPVT
                     PASEERGGALEGDSEESVSSNGGHFAELPCARRQQTSKGASALTEPLAPRGPMAHSRV
                     FVSTDDLLDCLVNPQVTRMVAQLLIQGKSCDTF"
     exon            155..340
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            341..522
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            523..659
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            660..831
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            832..915
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            916..1026
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..4606
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1575..1580
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /note="hexamer: AATATA"
     polyA_site      1598
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /note="major polyA site"
     regulatory      2557..2562
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2575
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /note="major polyA site"
     regulatory      2597..2602
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /note="hexamer: TATAAA"
     regulatory      2615..2620
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2621
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
     polyA_site      2648
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
     regulatory      4153..4158
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
                     /note="hexamer: AATATA"
     polyA_site      4173
                     /gene="Hspbap1"
                     /gene_synonym="3830421G21Rik"
ORIGIN      
        1 ggcagaggcg gaggatcctt cctgtgtgga agccgcagat cccggtgagc cctctcacct
       61 ggcgctctct ccatcctcgg cgcgataacc atggcagcag gctgcgaggg catcgcgccc
      121 ccgaccctgg gcgagagaac tgtgggggag gaaggtgaac ctgtcaaacc ttttacacca
      181 gagaaagcga aagagattat aatgtcttta cagcagcctg caatcttctg taacatggtt
      241 ttcgattggc catcacgaca ctggactgcg aaacaccttt cgaaggtctt ggagggcaag
      301 cagatacggt tcagaatggg cctgagaggc acaggcacag ttcctcagta tgaaaccgaa
      361 tgtagttatg tggatgcgac gctcgaggag tttttgacct ggaactgtga ccagtctagt
      421 atctctggac cattcaaaga ttatgaacat tctaaattct gggcttacgc tgactataag
      481 tattttgtta ctctgtttga ggacaagaca gatgttttcc aggaggtggt gtggtctgac
      541 tttgggtttc ctggaagaaa tggacaagaa agtacactgt ggatcgggtc ctttggagcc
      601 cacactccct gccatctgga ctcctatggt tgcaacttag tattccaggt acaaggaagg
      661 aaaagatggc atctctttcc tcctgaagat acgcctttcc tttatccaac cagaattcct
      721 tacgaagagt ctagtgtgtt cagtaaaatc aatgttgtca accctgattt gaagtgtttc
      781 ccccagttcc agaaagctcg aagacatatg gtcacgttga gcccaggaca ggttctgttt
      841 gttcccagac actggtggca ttacgtggag tctcttgatc ctgtcaccgt cagtataaac
      901 tcctggattg agctggaaga ggaccaccta gcgcgggtgg aggaggccat cacccgcatg
      961 ctcgtgtgta cactgaagac tgcagaggac ccgcaccacc ccaggacctg gctgaacccc
     1021 actgaggttg aggagacatc tcacgaggtc aacagctgct acttgaacag tgctgtttgt
     1081 gccttttttg atcattgtga aaaagctaaa gcagtagagt tgcaagtgct gagcgcaaac
     1141 ggggcggagc cacgtgtgca ggaggagcac atggaagtgg agcaggccca gggcccgagc
     1201 ctcacatcga gggctgagaa acaggaggcc gtgagcctgt ttggcccaga tctgatccct
     1261 gtgacaccag catccgaaga gagaggaggc gcactggaag gcgacagcga agaatctgtc
     1321 agcagtaatg gaggacactt tgcagaactg ccctgtgcca ggagacagca aaccagcaaa
     1381 ggggcgagcg cattgacgga gcccttggcc ccgaggggtc ctatggcgca ttctcgagtc
     1441 ttcgtgtcca cagatgactt gctggactgc ctagttaatc cacaagtaac caggatggtg
     1501 gcccagcttt tgatacaagg aaaaagctgt gatactttct agtaactttt taattacttt
     1561 ttaataactt ttaaaatata tttttagaaa taatatgata tacgtgtata tttgcttttt
     1621 atgatttttt acttgctctt tgaatatgtc atgtatatac tgtatatttt gattacattc
     1681 atgctgcact gcacctccag ccacttccaa atcccctttg tcccaaattt tctctcttta
     1741 tttatttact tttttttcac aacccattga gtccagttgc tgctagccag atacatataa
     1801 tatggctatc cacttagccc tggttaacca gggttgtacc actgaagaaa actcaacttt
     1861 ccttctggac gcagccatca atagctcctt agctagcgct gggagccctt gtgtccacat
     1921 tagaatattg actggcttgc tcttgcacag gcgaccacac tatagctgca gagttcacag
     1981 gcaaaccggt tctgtcctgt ccactccaaa agccattgct ttgcctcacc cctccctgat
     2041 ctctgacctg taaaaactcc cagcccctct ttctccagct tctttttcct ttcccttggt
     2101 agggaacagg gggggttgaa actggatcca actatgtagc tctctctggc tttccaggag
     2161 ctctcagtat agaccaggct ggtcctgaac tctcaagaga tccaccagcc tccacttcca
     2221 gggtgctggg atcaaaggcg ttcgccacct ccctgtttct cctggctctg tgttagccag
     2281 cattcactgt acaaagtgct ccttgggtaa ggaaggatca tctagaaagg acccagaagg
     2341 cagtttgatg ttttgttcat ttagcaaaac gataggagta ggttcacttc caggcctcac
     2401 aagccagggg tcctggctgg attgagagtt tgtttttaca gggtcccact gtatacctta
     2461 gactggcctt gaattcaaga tcctctggcc cgcctcccca agcgatggat tacaggttta
     2521 cactaccaag gttggttctc aatagtatga ttctaaaata aaggatggaa caggaggtgg
     2581 tgagtttgta catgtttata aatgtgcttt ccccaataaa atgccactgt ggtcacctct
     2641 ttccagcaca tcgctcagta gccaaactag ctagctcaca tttgggttgg tcttggtttg
     2701 ttaggtaaga ctcggctgca aagcagtctg aaaggctgag gtcctctgaa gtggggtaga
     2761 tgggcatggc tacagaatgg ccccagcgtt cgttcggcat cgcttgagcg tcctgttcag
     2821 acaattttgg caggctgcag cgctctccat tgttacaaac actaatcaag taagacagct
     2881 ttcctctggt tttaaaggca cacaagcatt tacgtttcat tactttatga agcttctcag
     2941 gaggcacagt ttctctgcat acatagggtt gttacagaat ggactcagtg tcgactgggc
     3001 tcagagaagc tgggacggtc ttctgcagga agtctttctt tcatgagaag gaagtatctt
     3061 attgtcctgt agtcttagag gttcactgcc tcggtctgct aacccaggcc tacgcctagg
     3121 cctggaagct tctagcctct gtacaatcta atctaagcct agaacgtttt cagcctctga
     3181 gccttactgc tgaataagct caccctttcc tagttctttc tggctcaaac tcctctccag
     3241 gctgactgaa ccaatctagc ttctctcagt ttctcctgag ttgctctgct tggcttcaga
     3301 ttaactctgg caatctgttc tgatcttctg gctccttctc attctctggc tagttctatc
     3361 ttcacctatg tctagcttgt tctctctctg caacctgtct atactactgt cctggtaaac
     3421 tgcctcattc ccctctctgc attgtccctt aagtagcttc ccttcctcct ctcttctcac
     3481 aagagttcga catattctat tctgtcaagt ctttctctga ttcatcactt tgccactcaa
     3541 ttagacatca ctttcaaaca tggatagttt ccttctacaa acttaacttt acctacatcg
     3601 tttgagatta aaggtaagta ctaaggacgt gtctatacac catcaaaagg gattaaaagc
     3661 atgtacaaag ggttgaacca caccacaaat agaaacaggc tttttttttt ccagtttata
     3721 actcaaatct cgatgggggt tcgttcatgg tgtgattaaa tatcctgcaa caatgtctgt
     3781 aaaagtgggt ggtaggagat gagtccctga ttttgtagag ggcaattacg aggtcctggc
     3841 tgattgcaag ggcatccgaa tggtaagcac cgtgaaaacg ctcatgagct gttcccacat
     3901 caccctgcat ctccaaggac cacatctgag tcaggaaaat caactggtaa gtactctggc
     3961 tctgcatggg ccggcagagc tcagacgcat gcttagtatc gtccaatact gaaggacaag
     4021 tcagtagtgc tcacataccc acgtggtgtt caggaggcat ggtggactcc atgagaatgt
     4081 tttaattttt ttgtttgttt taatacatcc atgaatgtag cagtatagtt gtatagtctg
     4141 gatttttaaa aaaatatatt tatttttact taatgtgtga gaatgtttgc ctgcatgaat
     4201 tgatgtgtgc agttccctca caggtcagaa gggggcattg gctccctgga tctttagtta
     4261 cggatgacca taaactaccc tgtgggtgat aagaaccaaa cacgggtcct ctacaagaac
     4321 agtgttctta aacactgata agtaagcact ctgtccatct ctcctgtccc tgagtttagg
     4381 tttggttggt tggttggttg tttttcattg ttatctttta ttattttaca atatatttca
     4441 aaaactgcca ttatagttgc cttgagttct ctgagagcca tagaacacct agatacacat
     4501 aaacatagtc tgatatacca actgacctgg accatcacta aaaaagggga gggggctata
     4561 tatagttttt aaataaatgt gtgacaatgc aaaataaaaa cctgtt
//
