LOCUS       NM_175185               3144 bp    mRNA    linear   ROD 09-JUN-2024
DEFINITION  Mus musculus hydroxysteroid dehydrogenase like 1 (Hsdl1),
            transcript variant 3, mRNA.
ACCESSION   NM_175185
VERSION     NM_175185.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3144)
  AUTHORS   Blackshaw,S., Harpavat,S., Trimarchi,J., Cai,L., Huang,H.,
            Kuo,W.P., Weber,G., Lee,K., Fraioli,R.E., Cho,S.H., Yung,R.,
            Asch,E., Ohno-Machado,L., Wong,W.H. and Cepko,C.L.
  TITLE     Genomic analysis of mouse retinal development
  JOURNAL   PLoS Biol 2 (9), E247 (2004)
   PUBMED   15226823
REFERENCE   2  (bases 1 to 3144)
  AUTHORS   Garcia-Frigola,C., Burgaya,F., Calbet,M., Lopez-Domenech,G., de
            Lecea,L. and Soriano,E.
  TITLE     A collection of cDNAs enriched in upper cortical layers of the
            embryonic mouse brain
  JOURNAL   Brain Res Mol Brain Res 122 (2), 133-150 (2004)
   PUBMED   15010206
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC104882.30.
            
            On Mar 18, 2020 this sequence version replaced NM_175185.4.
            
            Transcript Variant: This variant (3), as well as variants 1 and 2,
            encodes isoform a.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC065074.1, AK088412.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849382, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-84                AC104882.30        68278-68361         c
            85-310              AC104882.30        60952-61177         c
            311-756             AC104882.30        59215-59660         c
            757-984             AC104882.30        58830-59057         c
            985-3144            AC104882.30        55164-57323         c
FEATURES             Location/Qualifiers
     source          1..3144
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 67.95 cM"
     gene            1..3144
                     /gene="Hsdl1"
                     /gene_synonym="2700067E09Rik"
                     /note="hydroxysteroid dehydrogenase like 1"
                     /db_xref="GeneID:72552"
                     /db_xref="MGI:MGI:1919802"
     exon            1..84
                     /gene="Hsdl1"
                     /gene_synonym="2700067E09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            85..310
                     /gene="Hsdl1"
                     /gene_synonym="2700067E09Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..1083
                     /gene="Hsdl1"
                     /gene_synonym="2700067E09Rik"
                     /note="isoform a is encoded by transcript variant 3;
                     inactive hydroxysteroid dehydrogenase-like protein 1"
                     /codon_start=1
                     /product="inactive hydroxysteroid dehydrogenase-like
                     protein 1 isoform a"
                     /protein_id="NP_780394.1"
                     /db_xref="CCDS:CCDS22708.1"
                     /db_xref="GeneID:72552"
                     /db_xref="MGI:MGI:1919802"
                     /translation="MAAVDSFYLLYREIARSCNCYMEALALVGAWYTARKSITVICDF
                     YSLVRLHFIPRLGSRPDLIKQYGRWAVISGATDGIGKAYAEELASHGLNVILISQEEE
                     KLQAAAKHIADTYRVETLVLVADFSRGREIYAPIREALRDRDIGILVNDVGAFYPYPQ
                     YFSQVPEDTLWDIVNVNIAAASLMVHIVLPGMVERKKGAIVTVSSGSCCKPTPQLAAF
                     SASKAYLDHFSRALQYEYASKGIFVQSLIPFYVTSSGAAPASFLHRCPWLAPSPRVYA
                     QHAVSTLGISKRTTGYWSHSIQFLFAQYMPEWLWVWGANLLNRSLRKEALSCQA"
     exon            311..756
                     /gene="Hsdl1"
                     /gene_synonym="2700067E09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            757..984
                     /gene="Hsdl1"
                     /gene_synonym="2700067E09Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            985..3144
                     /gene="Hsdl1"
                     /gene_synonym="2700067E09Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3110..3115
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hsdl1"
                     /gene_synonym="2700067E09Rik"
                     /note="hexamer: AATAAA"
     polyA_site      3144
                     /gene="Hsdl1"
                     /gene_synonym="2700067E09Rik"
                     /note="major polyA site"
ORIGIN      
        1 agcggacctg cggtggtgtc ccggggcggc ggccgcgcgg gcagcgggcg ggacgggctt
       61 cggagaccgc gcctctcgct gcaggtcgcc atggctgctg ttgacagctt ctacctcttg
      121 tacagggaaa tcgccaggtc ttgcaattgc tacatggaag ccttggcctt ggtgggagcc
      181 tggtacacag cccgaaagag catcaccgtc atctgtgact tctacagcct ggtcaggctg
      241 cacttcatcc ctcgcctggg gagcaggccc gacctgatca agcagtatgg aagatgggcg
      301 gtcatcagtg gggccaccga tggcattggg aaggcctatg cggaggagtt agcgagccac
      361 ggactcaatg tcatcctgat cagccaggaa gaggagaagc tgcaggccgc ggccaagcac
      421 atagccgaca cctacagggt agagacgctt gtcctggtgg cagacttcag cagaggccgg
      481 gagatttacg cccccatccg agaagccctg agagacagag acattggcat cctggtgaac
      541 gacgtgggtg cattctaccc ctaccctcag tatttcagcc aggtgcccga ggacacgctc
      601 tgggacatcg tgaacgtgaa catcgcagcc gccagcctga tggtgcacat cgtgctgcca
      661 gggatggtgg agagaaagaa gggcgccatc gtcaccgtgt cttctggttc ctgctgcaag
      721 cccaccccac agctggctgc cttctctgcg tccaaggcct atctggacca cttcagccga
      781 gccctgcagt acgagtatgc ctctaagggg atctttgtgc agagcctgat ccccttctac
      841 gtgaccagca gcggggctgc gcccgccagc ttcctgcaca gatgcccgtg gctggcgccg
      901 tcgccgagag tgtatgcaca gcatgcagtg tcgaccctgg gcatttcaaa aaggaccaca
      961 ggctactggt cccattccat tcagttcctc ttcgcacagt atatgcccga gtggctctgg
     1021 gtgtggggtg caaacctcct caaccgctcc ttacggaaag aggccttatc ctgccaagcc
     1081 tgagccagga ggctggggag aagcttggtt aagccacggt cacctacggt ttctggcgtt
     1141 tggaagaaca cattcactcc acctgtgtat cgtctcctac caagtcccta gtgcatcgcc
     1201 atccttcatg aggccgactg ttacgtctgt gagcaaacct cagggaccac atggttggcc
     1261 cagggcgcat ggccatgaag cctgaggaca gaacgggctg cttcctcaac acttggagcg
     1321 tgaccagctc gctcctgtat tgtccgtctt gtgctggtct ttttcttttt ctttctttct
     1381 tttttttttt tttttgagaa gtcacctgtt ttccttttac aggtgactga ttatagtatt
     1441 ggctttcaag atgttcctca ggctgggcgt gggggctcac gcctttaatg ccagcacttg
     1501 ggagcttgag acaggcctgg gctacatagt gagttccagg ccagccaggg acatgcagtt
     1561 aaacctgtcc ttgaaaaaaa aattaatgtt catcaggaag acaacagaaa agtgttattt
     1621 tcaaactgtg aactgggagt gcaggtgtta acagtagaca tgtgtcatgc tgcatagctc
     1681 catggggggt gtctgtgtgt acacactgcc tttccctaag gtcccttaga accatgtgtg
     1741 tgctgtgtgt ctgggtgaag ttatcgataa gactttacag tagactctgc caagacgagg
     1801 ttatgaggga gcccttccca gagtaaacgc ctgggctact ccctttcatg tgctgaaaga
     1861 ctttcaggct ctacgctgtg tgggcttgcc atgtcctacg acattgtttc tttgagtact
     1921 tttgtctttc ccactctgta ggtgggtttt gttgctaggc tgggacacat aataggttgt
     1981 ctttggatgt acctaagtgg tggttcctca ctgagtccgt gttctatctg acccccttca
     2041 gagcttgtta gagctggctt tcatacactt ttctatgtaa tccaatttct ccccaggagc
     2101 gttgttgata aaatcatcac gtgtttgtgg aatagtggtt gaaatatggg cagcttttgt
     2161 gcgtggtata aggtagttat tgaagtgatg ttagctcgtt tttagcctgt gtgatgaatg
     2221 tgtacattgt agggaatgct tttattagcg tgagggtcct ttacgtatat cccacaatat
     2281 gggggcacac tgaaacttag tggctttcgt tggtttataa aaccaacctc ttgggagggt
     2341 ctcataccca gcacgtggaa gcttggaagt catggcagct tgtgcagagt ggaggatgtg
     2401 gcgttgcccc ttgtggtgct gcgctgtgcc tgggaagtga gaatgagcgg cacgctggga
     2461 cttggatgga gttgctttag tgacatccca tcacctgtag gcccaagtgc actttgccca
     2521 ggacatcaga tgtgccattt taagttgtga ctcagatcta gatcagtgtc ttcatgtcct
     2581 cagatcatgg gcagactacc atgcttggag acagaggagg aggagcctcg gcggggacgg
     2641 ctaccttact gctgagaacc ttcgtgcatg tgataggcgg cagtacctcc acctgagacc
     2701 taatcacgca tggtgattag ggaggaaggc aggagactga ggggttcaag gccagcatgg
     2761 gctatatagt gaaactctgg ttcaggaaac aaaaacagca gcagagacgc actgtccgct
     2821 ctgtgtaagg tcctgtggcc cagtattcag acttgtctat caagtgcgga gtccttgctc
     2881 catgatgagg agtcagtgat gttctctcag caggactcag ctagaactcg gagcacagtg
     2941 atccgtggct gcagcagaag actcgaatca ggcaccttta ggcttcctag ctctcatagg
     3001 cagaccctct ctgctgagct agtctgcctg cccactgtgg acatggcttt ttaccaagga
     3061 aggaggaact cggaaccttt gtaactcatc ctgtgaatca gaacgtaaca ataaaagcat
     3121 cactgtttcc ttcaggtccc gcca
//
