LOCUS       XM_006540904            4511 bp    mRNA    linear   ROD 07-FEB-2024
DEFINITION  PREDICTED: Mus musculus HPS5, biogenesis of lysosomal organelles
            complex 2 subunit 2 (Hps5), transcript variant X1, mRNA.
ACCESSION   XM_006540904
VERSION     XM_006540904.4
DBLINK      BioProject: PRJNA169
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000073.7) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Sep 21, 2020 this sequence version replaced XM_006540904.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001635.27-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/01/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4511
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6J"
                     /db_xref="taxon:10090"
                     /chromosome="7"
     gene            1..4511
                     /gene="Hps5"
                     /gene_synonym="haze; hz; maroon; mr; ru-2; ru2"
                     /note="HPS5, biogenesis of lysosomal organelles complex 2
                     subunit 2; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 5 mRNAs, 37 ESTs, 385 long SRA
                     reads, 14 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 31 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:246694"
                     /db_xref="MGI:MGI:2180307"
     CDS             207..3587
                     /gene="Hps5"
                     /gene_synonym="haze; hz; maroon; mr; ru-2; ru2"
                     /codon_start=1
                     /product="BLOC-2 complex member HPS5 isoform X1"
                     /protein_id="XP_006540967.1"
                     /db_xref="GeneID:246694"
                     /db_xref="MGI:MGI:2180307"
                     /translation="MTFVPVIPEAYSHVLAEFESLDPLLTALRLDSSRLRCTSIAVSR
                     KWLALGSTGGGLNLIQKDGWKQRLFLSHREGAISQIACCSHDDDYVAVATSQGLVVVW
                     ELNQERRGKPERIHVSSEHKGRKVTALCWDTAVLRVFVGDHVGKVSAIKLNTLKQAKA
                     AAAFVMFPVQTVLTVDSCVVQLDYLDGRLLVSSLTRSFLCDTEREKFWKIGNKERHGE
                     YGACFFPGRCAGGQQPVIYCARPGSRMWEVNFDGEVLSTHQFKKLLSMPPLPVITARS
                     EPQYDHTVGSSQSLAFPKLLHLSEHCVLTWTEKGIYIFIPQNVQVLLWSEVKDIQDVA
                     VYKNELFCLHFNGKISHLSLLSVERCVERLLRRGLWDLAARTCCLFQNSIITSRARKT
                     LTADKLEHLKSQLDLTACSELISQLDDLILRFEPLESACSSRRSSISSHESFSILDSG
                     IYRIISSRRGSQSDEDSCSLHSQTFSEDERLKEFASHQEEEQPEQGCGANRNEESASH
                     SPVMSEVDKSEAFLPFSIALPFRSPSPLVSLQAVKDSVSSFVRKTTEKIGTLHGSPEL
                     KEPFESKDADRAHEEEVSAVTCPLEEDTEEKEIHQPPKEDRLQELTAATAEAMTKLLD
                     PLVLFEPKVLRMVLLEWLSQLEKTFAMKDFPGISNTSSPTVKSNLGAHLLGETEKRVL
                     DEESGEGRRVSLVTEEAGGQITCDPVSNLSEPSADRFRVCSPYAITNSLQRDLAELTT
                     LCLELNVLTSAMESVGGHVDRASQQLSPEILACRFLKKYFFLLDLKRAKESIKLTYDS
                     PCVWDTFVEGLKEMARSNPAYTELEEGDLPTGLQLLDGSVPSDSPLLIAFATRLYDRF
                     GESALRACIKFYPSISPSDIAQLCRHHPAQFLAYLDSLVKSRPEDQWPSFLEFLLQPE
                     SLRLEWLLLAVSHDAPPSTSTVDDEGHPRPHSHLLSWGYSQLILLLIKLPADFTTKEK
                     MTDICRSYGFWPGYLTLCLELERRREAFTNIVYLNDISLMEGDNGWIPETLEEWKLLL
                     HLLQTKSTRPAPQESLNGSLSDGPAPINVENVALLLAKAMGPDRAWSLLQECGLALEL
                     SEKFTRTCDILRIAERRQRALIQGMLEKCDRFLWSQQA"
ORIGIN      
        1 accaccgcgg ccgccatgac accttccgct agctcccgcc ctcccccacc gattcccgcc
       61 tgtttcgctt ctcctcctcc ggtctcgagc ggcggagagt ttcggggatt cggcttggct
      121 cgcctttctc cctagagagc atccggtccg gctccgtgag agaaattctg tgtctcttac
      181 agaacaaccg tcatctttct ggctaaatga cttttgtgcc agtgatacca gaagcctaca
      241 gccatgttct tgcagagttt gagtccttgg atccgttact cacagccctg aggctggact
      301 ccagtcgtct gaggtgtacc agcatagctg tgtctcggaa atggttggcg ttaggcagca
      361 caggaggagg actcaatctc attcagaaag atggctggaa gcaaaggctg tttctctctc
      421 accgggaagg ggcaatctct cagattgcct gctgctctca tgatgatgat tatgttgctg
      481 tagctaccag tcaaggtctt gtagttgttt gggaattaaa tcaagagcgt cgtgggaagc
      541 cagaacgaat tcatgtgtcc tcagaacaca aaggccgaaa agttactgcc ctctgttggg
      601 acacggctgt tctgagagtc tttgtcggtg accatgtggg caaagtatct gccatcaaac
      661 tcaacacttt gaaacaagca aaagcagctg ctgcctttgt gatgtttcct gtgcagacag
      721 tactaacagt ggactcgtgt gtcgtccagt tggattactt ggatggaaga ttacttgtgt
      781 cttcactgac tcgatccttc ttgtgtgaca ccgagaggga aaagttttgg aaaatcggaa
      841 ataaggaaag acatggagaa tatggggctt gtttcttccc cgggcggtgt gctgggggcc
      901 agcagcctgt gatctactgc gcccgcccag gctcccggat gtgggaagtg aactttgacg
      961 gggaagtgct cagtacacac cagttcaaga agctcctgtc aatgccaccc ctccctgtga
     1021 tcactgcaag atcagagcct cagtatgatc acacagttgg atcctcccag tctttggcat
     1081 tccccaaact cttgcatctt agtgaacact gtgtgctgac ttggacagaa aagggaattt
     1141 atattttcat tcctcagaat gttcaagttc ttctttggag tgaagtcaag gatattcagg
     1201 atgtagctgt ctacaagaat gaattgttct gtttacactt taatggaaaa atctcacatc
     1261 tttccctgtt gtctgtggag cgctgtgtag aacgcctgtt aaggagaggc ctgtgggacc
     1321 tggctgctcg cacatgctgt ctcttccaaa attctattat taccagcaga gcaagaaaaa
     1381 cattgactgc agataagttg gagcatttga agtctcagct ggaccttaca gcctgcagtg
     1441 aactaatttc tcagctggac gacttgatct taaggttcga gcctttggag tcggcgtgca
     1501 gcagcagaag aagctccatc tcatcgcatg aaagttttag catcttggac tctggtattt
     1561 atcgtatcat cagtagtaga agaggcagtc agtccgacga agattcttgt tcccttcaca
     1621 gccagacctt ctcagaagat gaaaggctta aagaatttgc ctcacaccag gaagaggagc
     1681 agccagagca gggctgtggt gccaatagga atgaagagag tgcttcccac agtccagtga
     1741 tgtctgaggt agataagagt gaagcttttc tgcccttcag cattgcactg ccatttcgtt
     1801 ctccatctcc cctcgtgtct cttcaggctg ttaaagacag tgtttctagc tttgtgcgta
     1861 aaactactga gaagattggc acccttcacg gaagccccga gctgaaagag ccttttgaat
     1921 ccaaggatgc tgaccgagca catgaagagg aagtgagtgc agtcacctgc cctctggagg
     1981 aggacactga ggagaaagaa attcatcaac ctcctaaaga agacaggctt caagaactca
     2041 cagcagcgac agcagaagca atgaccaagt tattggaccc tctggttctg tttgagccca
     2101 aggtgctaag aatggtttta cttgagtggc tttcacagtt agagaaaaca tttgccatga
     2161 aagacttccc cggcatttcc aataccagca gtccaaccgt gaaatcaaac ttgggtgcac
     2221 acctcctcgg tgagacagaa aagagagtat tagatgaaga gagtggagaa ggaagaaggg
     2281 tctctttagt cactgaagaa gctggaggtc agataacctg tgaccctgta agcaacctca
     2341 gtgagccctc ggctgaccgt tttcgagtat gctctccata cgccatcaca aacagccttc
     2401 agagggacct ggcggaattg acaacgttgt gcttggaact gaatgtgttg acttcagcaa
     2461 tggaaagcgt aggtgggcat gtggaccggg cttcacagca gctctctcca gaaatcctgg
     2521 cttgtcgttt cctaaagaag tacttttttc ttctggactt gaaaagagca aaggagagta
     2581 tcaagctcac ttacgacagc ccttgcgttt gggacacttt tgtcgaagga ctaaaagaaa
     2641 tggcaagatc taatcctgcc tacacggagc tggaagaagg agacctgccc acggggttac
     2701 agttactgga tggctccgtc ccttctgata gtcccttgtt gattgcattt gccacccggt
     2761 tgtatgatag atttggggag tcagcccttc gagcttgcat caagttttat ccgtccattt
     2821 cgccctccga catcgcacag ctttgccgtc atcatcctgc tcagttcttg gcctatctag
     2881 acagtctggt gaagtccagg ccggaagacc agtggccatc cttccttgag ttccttctac
     2941 aaccagagtc tttaagactt gaatggctgc ttttggcagt gtcccatgat gctccaccaa
     3001 gcacaagtac agtggatgat gaagggcacc ccaggcccca ttcacacttg ctttcttggg
     3061 gttatagtca gctgattctt cttcttatta aacttcctgc agactttaca accaaagaga
     3121 aaatgactga catctgtagg tcttacggtt tctggcctgg atatcttacc ctctgtctgg
     3181 agctggagag gaggagggag gccttcacca acattgtgta tctgaatgac ataagcctga
     3241 tggaagggga caatgggtgg atccctgaga ccttggagga atggaagctt ctcctacatc
     3301 tactacagac caagagcaca aggccagctc cccaggagtc actaaacggg agcctcagtg
     3361 atgggccagc ccctatcaat gtggagaatg tggccctcct gttagctaag gccatgggcc
     3421 cagatcgggc ctggtcactg ctacaggagt gtggtctggc tcttgagttg tcagaaaagt
     3481 tcaccagaac ctgtgatatc ctgaggattg ctgagagaag gcagagagcg ctgatacaag
     3541 gcatgcttga gaagtgtgac cgcttcctct ggtcgcagca ggcctagttg gggatctact
     3601 ttgaccaagt ggaatcctgc tctcgaccct gcagaggtct ttggcacaga agggaagagg
     3661 acaccccaaa acatgctgct gcagctgctg atgtctcatc accgcctggc cagcccttgg
     3721 cttttgtggc tctgtgacct cagagtttct caaggaagca gtgggctgac cttcactgga
     3781 agcagcctgg aggtgctccc tgctgggtcg gattctttgt gtacaccatg aatcagggaa
     3841 ttggtttcta ctgatgcaga tctgtaggga gcagaagctt tggtacagga agacataact
     3901 aatattgtaa actggagttc aatacttttt cttactgagt taggacctgg aacaatgaca
     3961 tcattcctgt tggcttatgt aataaatact gaagatccaa actagagttt taaataagac
     4021 tgcccatatc tgagttgagc tcagtttcaa gtatttttcc agtatgtatt tgatattctc
     4081 taatctaagc ctatacgtac tgactaatcc tggaaatata ttatctgtaa gttttggaga
     4141 gtgggtgacc caaacgctca cgccctctct tttatttttt ttatcgggtt atgcactttt
     4201 tccttcattc ctttctcttt ttttgtctta atttataacc ctcgctagcc tggaacatgt
     4261 aggtatacca ggctgtctcg actttaaata tctactgcct ctgcctcctg aatgttagaa
     4321 ttaagggttt gtgccatcac atatacttta aaattttatt ttaaaaagcc atagcaagag
     4381 aaagccacgc actaacataa atgataacaa atgattatat tagccaagcc atgtaactgg
     4441 attgtcattt atgaagcttt atgtagcctg ttatgttggt aataaatgat gaaggttttc
     4501 tttaaggaga a
//
