LOCUS       NM_001361645            1655 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus hippocalcin-like 1 (Hpcal1), transcript variant 2,
            mRNA.
ACCESSION   NM_001361645 XM_006515156
VERSION     NM_001361645.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1655)
  AUTHORS   Chen,T., Yuan,Z., Lei,Z., Duan,J., Xue,J., Lu,T., Yan,G., Zhang,L.,
            Liu,Y., Li,Q. and Zhang,Y.
  TITLE     Hippocalcin-Like 1 blunts liver lipid metabolism to suppress
            tumorigenesis via directly targeting RUVBL1-mTOR signaling
  JOURNAL   Theranostics 12 (17), 7450-7464 (2022)
   PUBMED   36438486
  REMARK    GeneRIF: Hippocalcin-Like 1 blunts liver lipid metabolism to
            suppress tumorigenesis via directly targeting RUVBL1-mTOR
            signaling.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1655)
  AUTHORS   Li,H., Bishop,K.M. and O'Leary,D.D.
  TITLE     Potential target genes of EMX2 include Odz/Ten-M and other gene
            families with implications for cortical patterning
  JOURNAL   Mol Cell Neurosci 33 (2), 136-149 (2006)
   PUBMED   16919471
REFERENCE   3  (bases 1 to 1655)
  AUTHORS   Oikawa,K., Kimura,S., Aoki,N., Atsuta,Y., Takiyama,Y., Nagato,T.,
            Yanai,M., Kobayashi,H., Sato,K., Sasajima,T. and Tateno,M.
  TITLE     Neuronal calcium sensor protein visinin-like protein-3 interacts
            with microsomal cytochrome b5 in a Ca2+-dependent manner
  JOURNAL   J Biol Chem 279 (15), 15142-15152 (2004)
   PUBMED   14739275
  REMARK    GeneRIF: visinin-like protein-3 interacts with microsomal
            cytochrome b5 in a Ca2+-dependent manner
REFERENCE   4  (bases 1 to 1655)
  AUTHORS   Kannan,K., Kaminski,N., Rechavi,G., Jakob-Hirsch,J., Amariglio,N.
            and Givol,D.
  TITLE     DNA microarray analysis of genes involved in p53 mediated
            apoptosis: activation of Apaf-1
  JOURNAL   Oncogene 20 (26), 3449-3455 (2001)
   PUBMED   11423996
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC138342.11 and AC154636.2.
            
            On Mar 29, 2018 this sequence version replaced XM_006515156.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR7652917.328041.1,
                                           SRR7345562.1283833.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-238               AC138342.11        73215-73452         c
            239-324             AC154636.2         149247-149332       c
            325-726             AC154636.2         129998-130399       c
            727-832             AC154636.2         128896-129001       c
            833-1655            AC154636.2         124617-125439       c
FEATURES             Location/Qualifiers
     source          1..1655
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 8.13 cM"
     gene            1..1655
                     /gene="Hpcal1"
                     /gene_synonym="NVL-3; NVP-3; Nvp3; VILIP3; Vnsl3; Vsnl3"
                     /note="hippocalcin-like 1"
                     /db_xref="GeneID:53602"
                     /db_xref="MGI:MGI:1855689"
     exon            1..238
                     /gene="Hpcal1"
                     /gene_synonym="NVL-3; NVP-3; Nvp3; VILIP3; Vnsl3; Vsnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            239..324
                     /gene="Hpcal1"
                     /gene_synonym="NVL-3; NVP-3; Nvp3; VILIP3; Vnsl3; Vsnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            325..726
                     /gene="Hpcal1"
                     /gene_synonym="NVL-3; NVP-3; Nvp3; VILIP3; Vnsl3; Vsnl3"
                     /inference="alignment:Splign:2.1.0"
     CDS             349..930
                     /gene="Hpcal1"
                     /gene_synonym="NVL-3; NVP-3; Nvp3; VILIP3; Vnsl3; Vsnl3"
                     /note="neural visinin-like protein 3"
                     /codon_start=1
                     /product="hippocalcin-like protein 1"
                     /protein_id="NP_001348574.1"
                     /db_xref="CCDS:CCDS25830.1"
                     /db_xref="GeneID:53602"
                     /db_xref="MGI:MGI:1855689"
                     /translation="MGKQNSKLRPEVLQDLREHTEFTDHELQEWYKGFLKDCPTGHLT
                     VDEFKKIYANFFPYGDASKFAEHVFRTFDTNSDGTIDFREFIIALSVTSRGKLEQKLK
                     WAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNN
                     DGKLSLEEFIKGAKSDPSIVRLLQCDPSSASQF"
     exon            727..832
                     /gene="Hpcal1"
                     /gene_synonym="NVL-3; NVP-3; Nvp3; VILIP3; Vnsl3; Vsnl3"
                     /inference="alignment:Splign:2.1.0"
     exon            833..1655
                     /gene="Hpcal1"
                     /gene_synonym="NVL-3; NVP-3; Nvp3; VILIP3; Vnsl3; Vsnl3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1650..1655
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hpcal1"
                     /gene_synonym="NVL-3; NVP-3; Nvp3; VILIP3; Vnsl3; Vsnl3"
                     /note="hexamer: AATAAA"
     polyA_site      1655
                     /gene="Hpcal1"
                     /gene_synonym="NVL-3; NVP-3; Nvp3; VILIP3; Vnsl3; Vsnl3"
                     /note="major polyA site"
ORIGIN      
        1 cccttccttc ccgggctggc ggcggctgcg ggtggtggac ctgcagagcg gccgtcgccc
       61 acacctcgct ctctcctggg ccggcggatc cttttgtctc tccgagcggc gaaggtcgca
      121 gagcaggcgc ggcggctgcg ggagcgcaaa cgcccgctct ctcggtcacc tccccagcct
      181 cggccaccgc agaacttggg ctcgagaagc cagcggaccg cgtccagctc cagagccggg
      241 gaatggtcta gcagcttatc gagcctgtgc atcatccccc agcagttctg atcctgctct
      301 gctttggcct ccatttggcc gtaggtttag tctccactgc cagctgccat gggcaagcag
      361 aacagcaagc tgcgtcctga ggtgctgcag gacctgcggg aacacacgga attcaccgac
      421 catgagcttc aggagtggta caagggcttc ctcaaggact gccccactgg ccacctgact
      481 gtggacgagt tcaagaagat ctacgccaac ttcttcccct acggcgatgc ctccaagttc
      541 gctgaacacg tcttccgcac cttcgacacc aacagcgatg gcaccatcga cttccgggag
      601 ttcatcattg ctctgagtgt gacctctcgg ggcaagctgg aacagaagct caagtgggcc
      661 tttagcatgt acgacctgga cggcaatggc tacatcagcc gcagtgaaat gctggagata
      721 gtgcaggcca tctacaagat ggtgtcctcc gtgatgaaga tgcctgagga cgagtccacg
      781 cccgaaaagc gaacagacaa gatcttcaga cagatggaca caaacaatga tggcaaactg
      841 tccctggaag aattcatcaa aggtgccaag agcgacccat ccattgtccg gttgctgcag
      901 tgtgatccca gcagtgctag ccagttctga ggggaatggg cttttggaca tttgtgagaa
      961 acacaggctt ggcctgccat gttcagcttt gcttgtaaaa gtggattcct ccgtgatctc
     1021 tcctgctctc ccaggacctg ggtccaggca gcaatcgcac cctcctgacc tggccaactg
     1081 tggcttcctc ctcctccagt tcaggctggc tccttccaat ggttcaagtg ttctcggctg
     1141 tagggctcct tcctgcccac agagggcctg gcggccctta aggacaccag acaggacttt
     1201 tcagtatctt accaagacca gctaatttat tctatgatcc cagatgactt tgtgaggatg
     1261 aaaaagatgg agagtagaca ggcaagccct tcctgtgcat ggctccacct cccttgttca
     1321 ttttctctga ccaaagccgc ttgcatgtat ataccgtggt atccttactt ttaatatatg
     1381 agttatatgt acggtgagat ggactataat gttcagcccc tgtatttaat gcctctgact
     1441 gcctttgaag catggtcccc tgtggcctgt gattcccccc acccccaagt ctggctgtgc
     1501 tgtgatattt atgcattcat gatttgcctg attccacagg agatacatgc atgcccaggg
     1561 ctgtggacat ctgcctccgt cctgtaaatg caggtgtttc tgtgtgctct gtccttcctg
     1621 tcgattggtc tggcatatta aaatgatcaa ataaa
//
