LOCUS       NM_008275               2572 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus homeobox D13 (Hoxd13), mRNA.
ACCESSION   NM_008275
VERSION     NM_008275.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2572)
  AUTHORS   Frenette,B., Gueno,J., Houde,N., Landry-Truchon,K., Giguere,A.,
            Ashok,T., Ryckman,A., Morton,B.R., Mansfield,J.H. and Jeannotte,L.
  TITLE     Loss of Hoxa5 function affects Hox gene expression in different
            biological contexts
  JOURNAL   Sci Rep 14 (1), 30903 (2024)
   PUBMED   39730789
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2572)
  AUTHORS   Soussi,G., Girdziusaite,A., Jhanwar,S., Palacio,V., Notaro,M.,
            Sheth,R., Zeller,R. and Zuniga,A.
  TITLE     TBX3 is essential for establishment of the posterior boundary of
            anterior genes and upregulation of posterior genes together with
            HAND2 during the onset of limb bud development
  JOURNAL   Development 151 (11) (2024)
   PUBMED   38828908
REFERENCE   3  (bases 1 to 2572)
  AUTHORS   Chen,Y., Zhou,T., Liao,Z., Gao,W., Wu,J., Zhang,S., Li,Y., Liu,H.,
            Zhou,H., Xu,C. and Su,P.
  TITLE     Hnrnpk is essential for embryonic limb bud development as a
            transcription activator and a collaborator of insulator protein
            Ctcf
  JOURNAL   Cell Death Differ 30 (10), 2293-2308 (2023)
   PUBMED   37608075
REFERENCE   4  (bases 1 to 2572)
  AUTHORS   Qu,F., Li,W., Xu,J., Zhang,R., Ke,J., Ren,X., Meng,X., Qin,L.,
            Zhang,J., Lu,F., Zhou,X., Luo,X., Zhang,Z., Wang,M., Wu,G., Pei,D.,
            Chen,J., Cui,G., Suo,S. and Peng,G.
  TITLE     Three-dimensional molecular architecture of mouse organogenesis
  JOURNAL   Nat Commun 14 (1), 4599 (2023)
   PUBMED   37524711
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2572)
  AUTHORS   Kumar,S., Alam,S.S., Bareke,E., Beauchamp,M.C., Dong,Y., Chan,W.,
            Majewski,J. and Jerome-Majewska,L.A.
  TITLE     Sf3b4 regulates chromatin remodeler splicing and Hox expression
  JOURNAL   Differentiation 131, 59-73 (2023)
   PUBMED   37167859
REFERENCE   6  (bases 1 to 2572)
  AUTHORS   Oefelein,M., Chin-Chance,C. and Bushman,W.
  TITLE     Expression of the homeotic gene Hox-d13 in the developing and adult
            mouse prostate
  JOURNAL   J Urol 155 (1), 342-346 (1996)
   PUBMED   7490883
REFERENCE   7  (bases 1 to 2572)
  AUTHORS   Scott,M.P.
  TITLE     Vertebrate homeobox gene nomenclature
  JOURNAL   Cell 71 (4), 551-553 (1992)
   PUBMED   1358459
REFERENCE   8  (bases 1 to 2572)
  AUTHORS   Dolle,P., Izpisua-Belmonte,J.C., Boncinelli,E. and Duboule,D.
  TITLE     The Hox-4.8 gene is localized at the 5' extremity of the Hox-4
            complex and is expressed in the most posterior parts of the body
            during development
  JOURNAL   Mech Dev 36 (1-2), 3-13 (1991)
   PUBMED   1685889
REFERENCE   9  (bases 1 to 2572)
  AUTHORS   Dolle,P., Izpisua-Belmonte,J.C., Brown,J.M., Tickle,C. and
            Duboule,D.
  TITLE     HOX-4 genes and the morphogenesis of mammalian genitalia
  JOURNAL   Genes Dev 5 (10), 1767-1767 (1991)
   PUBMED   1680771
REFERENCE   10 (bases 1 to 2572)
  AUTHORS   Ryder,K., Lanahan,A., Perez-Albuerne,E. and Nathans,D.
  TITLE     jun-D: a third member of the jun gene family
  JOURNAL   Proc Natl Acad Sci U S A 86 (5), 1500-1503 (1989)
   PUBMED   2493644
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL928644.12.
            
            On Jun 21, 2019 this sequence version replaced NM_008275.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK077862.1, AB221620.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-854               AL928644.12        153157-154010
            855-2572            AL928644.12        154818-156535
FEATURES             Location/Qualifiers
     source          1..2572
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 44.13 cM"
     gene            1..2572
                     /gene="Hoxd13"
                     /gene_synonym="Hox-4.8; spdh"
                     /note="homeobox D13"
                     /db_xref="GeneID:15433"
                     /db_xref="MGI:MGI:96205"
     exon            1..854
                     /gene="Hoxd13"
                     /gene_synonym="Hox-4.8; spdh"
                     /inference="alignment:Splign:2.1.0"
     exon            855..2572
                     /gene="Hoxd13"
                     /gene_synonym="Hox-4.8; spdh"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2265..2270
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hoxd13"
                     /gene_synonym="Hox-4.8; spdh"
                     /note="hexamer: AATAAA"
     polyA_site      2289
                     /gene="Hoxd13"
                     /gene_synonym="Hox-4.8; spdh"
                     /note="major polyA site"
     regulatory      2543..2548
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hoxd13"
                     /gene_synonym="Hox-4.8; spdh"
                     /note="hexamer: AATAAA"
     polyA_site      2572
                     /gene="Hoxd13"
                     /gene_synonym="Hox-4.8; spdh"
ORIGIN      
        1 acacagcgag gagggaggag gcgcagcgcg ccatggtgtc ctgcgcgggg ccgaggccgg
       61 ggcccgggcc gggccaggcc gggccatgag ccgctcgggg acttgggaca tggatgggct
      121 gcgggcggac ggcggggccg ctggggcggc accggcctcc tcctcctcct ccgtagcagc
      181 gcctggccag tgtcgcggct tcctgtcggc gccggtgttc gcggggacac attccggacg
      241 cgcggcggcg gcggccgcag cagcggcggc ggcagcggcg gcagcatcca gcttcgctta
      301 cccagggacc tctgagcgca caggctcttc gtcgtcgtcg tcatcctcgg ctgtgatcgc
      361 cactcgcccc gaggctcctg tggccaaaga gtgtcccgcg ccagcggccg ccgcgaccgc
      421 tgcagcaccg ccgggcgctc ccgcgctggg ctatggctac cacttcggca acggttacta
      481 cagctgccgc atgtcgcacg gcgtaggctt acagcagaac gctctcaagt cgtccccgca
      541 cgcttctctc ggaggtttcc cggtggagaa gtacatggac gtgtcgggcc tggcgagcag
      601 cagcgtaccg accaacgagg tgcccgcaag agccaaggaa gtgtccttct accagggcta
      661 cacaagtccc tatcagcacg tgcctggcta catcgacatg gtgtccactt ttggatccgg
      721 ggaacctcgg cacgaggcat acatctccat ggagggctac cagtcctgga cgctagccaa
      781 cgggtggaac agccaggtgt actgtgccaa ggatcagcca caggggtccc atttttggaa
      841 atcatccttt ccaggagatg tggctttaaa ccagccggac atgtgcgtct accgacgggg
      901 aaggaagaaa agggtgcctt acaccaaact gcagctcaaa gaactggaga atgagtatgc
      961 cattaacaag ttcattaaca aggacaagcg gcggcggatc tcagctgcca cgaacctttc
     1021 ggagagacaa gtaaccattt ggtttcagaa tcgaagggtg aaggacaaga aaatcgtctc
     1081 caagctcaaa gacactgtct cctgatgtgg gccaggttgg ccacagacag tttaaatgcg
     1141 ttcagttgtc tccaaaaaaa tacctttgaa aagacttgaa aatgtattta atttccctcc
     1201 cccttccctg cctagaaagg caagcattgt gaatcctttt cccccctctc tatctctctc
     1261 tctctctctt gacctttatc tggttctaaa actttttgct gcccaatccg actttgtaat
     1321 tctatttctt acttgcttat tattggtttt gttcttgtct aggtttgttt ttataatttt
     1381 taaacattgt ttctccctcc aggccagtat gaggaaaaaa aaacttgaag tatttttttc
     1441 aataatcccc ccaaatgaat ttcagaagtg cccttgtatt taggggttta tttttttaac
     1501 aggattttat atgtgtttcc agcactgatt atgcttataa tccattaggc cagaatcgtt
     1561 ttttttagcc tttcataccc tgtgattgtg taattgaatc attagctctc agaagtttcc
     1621 ccaaggcaag tggaaacagc tcttaggcat taggtgattt aggaccgctg ggagagtctg
     1681 aaacttggag gttgaaggca cgtgatgact ttaaaagcag ctaccttatt aatattgaaa
     1741 ttaagacaat cacccttatc tttggcagtc tcctttgctg ttttgtgtgg ttttaacatg
     1801 tcttgtagct gtgatttttg aacctgaaaa cagcattcct agtggatgcc tttatttctc
     1861 caactctaca tgcagctatt aaaatactta cacttggcag agtgactgga gatagtataa
     1921 attcatcccg ttccttgggt ctgtgggaat ggagctaagg ccatctcctc aatccttgga
     1981 aagagactca gccaatgtgg ccatgggtgg gaacttctgt ccagagctca gtgaagaagt
     2041 taattgtctg aatgcatggg cctctcagag ctttaaaata tctaacacat tttttaaata
     2101 tggagctcta aggaccaaga gggaaaaaga aacttctgaa agtgatgaac tactttcaaa
     2161 aatgttgcgt atttatggga ctgaaagatt atttttgtag atacagtgtg tgtgagcagt
     2221 gcttcgagca tttaaaaatc acattttact cctagggaga tataaataaa aagaactctc
     2281 ttgtctccac tgagtcttca tccatttgtg tttttcaagc ttgtgctgcc tctagaagct
     2341 gtttttattt attataaaac tttgctctcc tcgacatctg tagatgaagg aaacaacacc
     2401 agttctggtc tctgaaacct ccatgttctg ttctccattt ctgtccacct ccttctaaca
     2461 caaatagtga tgtttaaaat gaggatatca tctgtgatgt ctaaaatcat cattttaaaa
     2521 ccagaccaac tcattaaaaa tcaataaatt ttatttcttt caatattatc aa
//
