LOCUS       NM_008266               2077 bp    mRNA    linear   ROD 11-OCT-2023
DEFINITION  Mus musculus homeobox B1 (Hoxb1), mRNA.
ACCESSION   NM_008266
VERSION     NM_008266.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2077)
  AUTHORS   Di Bonito M, Bourien J, Tizzano M, Harrus AG, Puel JL, Avallone B,
            Nouvian R and Studer M.
  TITLE     Abnormal outer hair cell efferent innervation in Hoxb1-dependent
            sensorineural hearing loss
  JOURNAL   PLoS Genet 19 (9), e1010933 (2023)
   PUBMED   37738262
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2077)
  AUTHORS   Petrelli B, Ozturk A, Pind M, Ayele H, Fainsod A and Hicks GG.
  TITLE     Genetically programmed retinoic acid deficiency during gastrulation
            phenocopies most known developmental defects due to acute prenatal
            alcohol exposure in FASD
  JOURNAL   Front Cell Dev Biol 11, 1208279 (2023)
   PUBMED   37397253
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2077)
  AUTHORS   Afzal Z, Lange JJ, Nolte C, McKinney S, Wood C, Paulson A, De Kumar
            B, Unruh J, Slaughter BD and Krumlauf R.
  TITLE     Shared retinoic acid responsive enhancers coordinately regulate
            nascent transcription of Hoxb coding and non-coding RNAs in the
            developing mouse neural tube
  JOURNAL   Development 150 (10) (2023)
   PUBMED   37102683
REFERENCE   4  (bases 1 to 2077)
  AUTHORS   Ramachandran J, Zhou W, Bardenhagen AE, Nasr T, Yates ER, Zorn AM,
            Ji H and Vokes SA.
  TITLE     Hedgehog regulation of epithelial cell state and morphogenesis in
            the larynx
  JOURNAL   Elife 11, e77055 (2022)
   PUBMED   36398878
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2077)
  AUTHORS   Chen CH and Behringer RR.
  TITLE     Transgenic human HOXB1-9 directs anterior-posterior axial skeleton
            pattern in Hoxb1-9 deficient mice
  JOURNAL   Differentiation 127, 1-11 (2022)
   PUBMED   36041259
REFERENCE   6  (bases 1 to 2077)
  AUTHORS   Scott,M.P.
  TITLE     Vertebrate homeobox gene nomenclature
  JOURNAL   Cell 71 (4), 551-553 (1992)
   PUBMED   1358459
REFERENCE   7  (bases 1 to 2077)
  AUTHORS   Conlon RA and Rossant J.
  TITLE     Exogenous retinoic acid rapidly induces anterior ectopic expression
            of murine Hox-2 genes in vivo
  JOURNAL   Development 116 (2), 357-368 (1992)
   PUBMED   1363087
REFERENCE   8  (bases 1 to 2077)
  AUTHORS   Frohman MA and Martin GR.
  TITLE     Isolation and analysis of embryonic expression of Hox-4.9, a member
            of the murine labial-like gene family
  JOURNAL   Mech Dev 38 (1), 55-67 (1992)
   PUBMED   1356009
REFERENCE   9  (bases 1 to 2077)
  AUTHORS   Nazarali A, Kim Y and Nirenberg M.
  TITLE     Hox-1.11 and Hox-4.9 homeobox genes
  JOURNAL   Proc Natl Acad Sci U S A 89 (7), 2883-2887 (1992)
   PUBMED   1348361
REFERENCE   10 (bases 1 to 2077)
  AUTHORS   Murphy P and Hill RE.
  TITLE     Expression of the mouse labial-like homeobox-containing genes, Hox
            2.9 and Hox 1.6, during segmentation of the hindbrain
  JOURNAL   Development 111 (1), 61-74 (1991)
   PUBMED   1673098
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK017686.1, BC103598.1, AW537768.1, CF582525.1 and CF582524.1.
            
            [WARNING] On Jan 17, 2024 this sequence was replaced by
            NM_008266.6.
            
            On Apr 14, 2009 this sequence version replaced NM_008266.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK017686.1, BC103597.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN01164134
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-718               AK017686.1         2-719
            719-1455            BC103598.1         716-1452
            1456-1500           AW537768.1         1-45                c
            1501-1516           CF582525.1         581-596             c
            1517-1545           CF582524.1         49-77
            1546-2077           CF582525.1         18-549              c
FEATURES             Location/Qualifiers
     source          1..2077
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 59.86 cM"
     gene            1..2077
                     /gene="Hoxb1"
                     /gene_synonym="Hox-2.9"
                     /note="homeobox B1"
                     /db_xref="GeneID:15407"
                     /db_xref="MGI:MGI:96182"
     exon            1..634
                     /gene="Hoxb1"
                     /gene_synonym="Hox-2.9"
                     /inference="alignment:Splign:2.1.0"
     CDS             70..963
                     /gene="Hoxb1"
                     /gene_synonym="Hox-2.9"
                     /note="homeobox protein Hox-2.9; homeo box B1"
                     /codon_start=1
                     /product="homeobox protein Hox-B1"
                     /protein_id="NP_032292.3"
                     /db_xref="CCDS:CCDS25300.1"
                     /db_xref="GeneID:15407"
                     /db_xref="MGI:MGI:96182"
                     /translation="MDYNRMSSFLEYPLCNRGPSAYSAPTSFPPCSAPAVDSYAGESR
                     YGGGLPSSALQQNSGYPVQQPPSSLGVSFPSPAPSGYAPAACNPSYGPSQYYSVGQSE
                     GDGSYFHPSSYGAQLGGLPDSYGAGGVGSGPYPPPQPPYGTEQTATFASAYDLLSEDK
                     ESPCSSEPSTLTPRTFDWMKVKRNPPKTAKVSELGLGAPGGLRTNFTTRQLTELEKEF
                     HFNKYLSRARRVEIAATLELNETQVKIWFQNRRMKQKKREREGGRMPAGPPGCPKEAA
                     GDASDQSACTSPEASPSSITS"
     exon            635..2077
                     /gene="Hoxb1"
                     /gene_synonym="Hox-2.9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atactgccga aaggttgtag ggcaagaggg tgtctccccc aaacggcccg accctccttc
       61 ggcctctaca tggactataa taggatgagt tcctttttag agtacccact ttgtaaccgg
      121 ggacccagcg cctacagcgc cccaacctct tttcccccct gctcagctcc ggccgttgac
      181 agctacgcag gggagagccg ctatggtgga gggctgccta gctcagcgct ccaacaaaac
      241 tcggggtatc ctgtccagca gccgccgtca tccctggggg tgtcctttcc cagccccgct
      301 ccctcggggt acgccccagc cgcctgcaac cccagctatg ggccttctca gtattattct
      361 gtgggtcagt cggaaggaga tggaagctat tttcatccgt cgagctacgg agcccagcta
      421 ggggggttgc ccgacagcta tggagcgggt ggagtcggct cagggccata tcctccgccg
      481 cagcccccat acggaactga gcagaccgca acctttgcat cagcctacga cctcctctct
      541 gaggacaagg aatcgccttg ctcgtcagaa cccagcactc tcactccccg gaccttcgac
      601 tggatgaagg tcaagagaaa cccacctaag acagcgaagg tgtccgagct gggactgggc
      661 gctcccggcg gtctccgcac aaacttcacc acgcgccagc tgacggagct ggagaaggaa
      721 tttcatttca acaaatacct gagccgtgcc cggagggtgg agatcgccgc caccctggag
      781 ctcaatgaaa cgcaggtgaa gatctggttc cagaaccggc gcatgaagca gaagaaacgc
      841 gagcgagagg ggggcaggat gcctgcaggc cccccaggtt gcccaaagga agccgctgga
      901 gatgcctctg accagtccgc gtgcacctcc ccagaagcct cgcccagttc catcacctct
      961 tgaattgaac ttcctaagta actgggcttc caacgcttga ccagttctct cgaagacttt
     1021 cccaaacttc acagccttgg tgaccctcct caaggccgag gcaccagttt agagctgccc
     1081 aggaaactgg gcaggagttg ggaaatgtat ttttctctct ctcagatcta ggggtggagg
     1141 gatgattgat ggctggggat cctacaggtc ttgggacctg gggaacactc aactcatcag
     1201 aggtcgaagg aaggcctttt ggctttgatc tggagtcagc ccatcctttc gggcttctcc
     1261 tttcccttcc aactcagttc agtgcctttg agcttagaga gttcttcttt cgaattctta
     1321 gcccaactct tctttctagg tctgggatgt ctaggctggg agtccttggg gtttttctgg
     1381 gggaggatgc gtttgagtgt gagcccaatc gccaccaacc cttaatctta atccagccaa
     1441 ctcaccgcag accttacaat agcagacctt acaatagcac cgactgcctt gtgacatacc
     1501 aaaaaaaaaa aaaaacaaaa aaaacaaaaa aaaacaaaac aaaacaaaaa aaaacaaaaa
     1561 aaaccccaca aaaacaaaaa caaaaaaaaa aaacaacctt actcccaagt aatcccacaa
     1621 cccttttcct ggcacatgtc ttttgcacta atgcagccct cagaggctgg cttacgagac
     1681 tctccccttc ccactggcat cacaaaatca ccaaagtgtt ttggaacttg gcactatgga
     1741 gatttccaga gcatcattgc aaggactgcc tcaagcaagc ctcaaccaag aaggggcgaa
     1801 taccccctcc caactcccta tttattacct ccggaaaagc ccacccccca aacctccctc
     1861 cccagcccat tctcctttcc ataaaaccac cctacccctg gggcagtctg gggaggccca
     1921 ggaatggtga cagagtttcc agtctcttca gacatttctc caaaccccgg agacagcaga
     1981 gaggccactt gagtttctag aaaaccaagc tccaagcaag ccaggttctc tttgtatctg
     2041 caactacctc attgcaataa agtctgtttt tctccct
//
