LOCUS       NM_001419271            2183 bp    mRNA    linear   ROD 28-JAN-2025
DEFINITION  Mus musculus homeobox A7 (Hoxa7), transcript variant 6, mRNA.
ACCESSION   NM_001419271
VERSION     NM_001419271.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2183)
  AUTHORS   Frenette,B., Gueno,J., Houde,N., Landry-Truchon,K., Giguere,A.,
            Ashok,T., Ryckman,A., Morton,B.R., Mansfield,J.H. and Jeannotte,L.
  TITLE     Loss of Hoxa5 function affects Hox gene expression in different
            biological contexts
  JOURNAL   Sci Rep 14 (1), 30903 (2024)
   PUBMED   39730789
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2183)
  AUTHORS   Oikonomakos,I., Tedesco,M., Motamedi,F.J., Peitzsch,M., Nef,S.,
            Bornstein,S.R., Schedl,A., Steenblock,C. and Neirijnck,Y.
  TITLE     In vitro differentiation of mouse pluripotent stem cells into
            corticosteroid-producing adrenocortical cells
  JOURNAL   Stem Cell Reports 19 (9), 1289-1303 (2024)
   PUBMED   39178848
REFERENCE   3  (bases 1 to 2183)
  AUTHORS   Catela,C., Chen,Y., Weng,Y., Wen,K. and Kratsios,P.
  TITLE     Control of spinal motor neuron terminal differentiation through
            sustained Hoxc8 gene activity
  JOURNAL   Elife 11, e70766 (2022)
   PUBMED   35315772
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2183)
  AUTHORS   Yoshioka,K., Nagahisa,H., Miura,F., Araki,H., Kamei,Y.,
            Kitajima,Y., Seko,D., Nogami,J., Tsuchiya,Y., Okazaki,N.,
            Yonekura,A., Ohba,S., Sumita,Y., Chiba,K., Ito,K., Asahina,I.,
            Ogawa,Y., Ito,T., Ohkawa,Y. and Ono,Y.
  TITLE     Hoxa10 mediates positional memory to govern stem cell function in
            adult skeletal muscle
  JOURNAL   Sci Adv 7 (24) (2021)
   PUBMED   34108202
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2183)
  AUTHORS   Higashijima,Y., Nagai,N., Yamamoto,M., Kitazawa,T., Kawamura,Y.K.,
            Taguchi,A., Nakada,N., Nangaku,M., Furukawa,T., Aburatani,H.,
            Kurihara,H., Wada,Y. and Kanki,Y.
  TITLE     Lysine demethylase 7a regulates murine anterior-posterior
            development by modulating the transcription of Hox gene cluster
  JOURNAL   Commun Biol 3 (1), 725 (2020)
   PUBMED   33257809
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2183)
  AUTHORS   Scott,M.P.
  TITLE     Vertebrate homeobox gene nomenclature
  JOURNAL   Cell 71 (4), 551-553 (1992)
   PUBMED   1358459
REFERENCE   7  (bases 1 to 2183)
  AUTHORS   Walmer,D.K., Wrona,M.A., Hughes,C.L. and Nelson,K.G.
  TITLE     Lactoferrin expression in the mouse reproductive tract during the
            natural estrous cycle: correlation with circulating estradiol and
            progesterone
  JOURNAL   Endocrinology 131 (3), 1458-1466 (1992)
   PUBMED   1505477
REFERENCE   8  (bases 1 to 2183)
  AUTHORS   Kessel,M.
  TITLE     Respecification of vertebral identities by retinoic acid
  JOURNAL   Development 115 (2), 487-501 (1992)
   PUBMED   1358593
REFERENCE   9  (bases 1 to 2183)
  AUTHORS   Dush,M.K. and Martin,G.R.
  TITLE     Analysis of mouse Evx genes: Evx-1 displays graded expression in
            the primitive streak
  JOURNAL   Dev Biol 151 (1), 273-287 (1992)
   PUBMED   1349539
REFERENCE   10 (bases 1 to 2183)
  AUTHORS   Nazarali,A., Kim,Y. and Nirenberg,M.
  TITLE     Hox-1.11 and Hox-4.9 homeobox genes
  JOURNAL   Proc Natl Acad Sci U S A 89 (7), 2883-2887 (1992)
   PUBMED   1348361
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC015583.34.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17253011.7429352.1,
                                           SRR14995045.1839195.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-453               AC015583.34        95884-96336
            454-643             AC015583.34        96707-96896
            644-2183            AC015583.34        97336-98875
FEATURES             Location/Qualifiers
     source          1..2183
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 25.4 cM"
     gene            1..2183
                     /gene="Hoxa7"
                     /gene_synonym="Hox-1.1; M6"
                     /note="homeobox A7"
                     /db_xref="GeneID:15404"
                     /db_xref="MGI:MGI:96179"
     exon            1..453
                     /gene="Hoxa7"
                     /gene_synonym="Hox-1.1; M6"
                     /inference="alignment:Splign:2.1.0"
     CDS             145..957
                     /gene="Hoxa7"
                     /gene_synonym="Hox-1.1; M6"
                     /note="isoform 3 is encoded by transcript variant 6;
                     HOMEOBOX PROTEIN HOX-A7 (HOX-1.1) (M6-12) (M6)"
                     /codon_start=1
                     /product="homeobox protein Hox-A7 isoform 3"
                     /protein_id="NP_001406200.1"
                     /db_xref="GeneID:15404"
                     /db_xref="MGI:MGI:96179"
                     /translation="MPSRLLAPLHPTRREAATGRAPAPSPPLCRAYTMSTAPSIRAPS
                     RPAMAWEPTPTTCPAPPTTKTSPGSAVTSPKAPATRRTRACFTARPKPVSASTPGCAV
                     QSFFLSPSFLSSISFLTPALSPLLPFFRPGFLSQRQGELRPPGSLTHHCTRGHFQNGA
                     EANGTEGPDRKRGRQTYTRYQTLELEKEFHFNRYLTRRRRIEIAHALCLTERQIKIWF
                     QNRRMKWKKEHKDESQAPTAAPEDAVPSVSTAADKADEEEEEEEEEEEEEEE"
     exon            454..643
                     /gene="Hoxa7"
                     /gene_synonym="Hox-1.1; M6"
                     /inference="alignment:Splign:2.1.0"
     exon            644..2183
                     /gene="Hoxa7"
                     /gene_synonym="Hox-1.1; M6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2158..2163
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hoxa7"
                     /gene_synonym="Hox-1.1; M6"
                     /note="hexamer: AATAAA"
     polyA_site      2183
                     /gene="Hoxa7"
                     /gene_synonym="Hox-1.1; M6"
                     /note="major polyA site"
ORIGIN      
        1 gtaatgttat catatatcac gctacctcgt aaaaccgaca ctgaaagctg ccggacaaca
       61 aatcacaggt caaaattatg agttcttcgt attatgtgaa cgcgcttttt agcaaatata
      121 cggcgggggc ttctctcttc caaaatgccg agccgacttc ttgctccttt gcacccaact
      181 cgcagagaag cggctacggg ccgggcgccg gcgccttcgc ctccactgtg ccgggcttat
      241 acaatgtcaa cagccccctc tatcagagcc ccttcgcgtc cggctatggc ctgggagccg
      301 acgcctacaa cctgccctgc gcctcctacg accaaaacat ccccgggctc tgcagtgacc
      361 tcgccaaagg cgcctgcgac aaggcggacg agggcgtgct tcacggcccg gccgaagcca
      421 gtttccgcat ctacccctgg atgcgcagtt cagtctttct ttctatcccc ctcttttctg
      481 tcctctatct ctttcttgac tccagctctc tctcccctcc ttcccttctt tcggcctggc
      541 tttctttctc aaaggcaagg agaattgaga cctccgggat ccctcactca tcactgtacc
      601 agaggccatt tccagaacgg ggctgaagcc aatgggacag agggacccga caggaagcgg
      661 ggacgccaga cctacacgcg ctaccagacg ctggaactgg agaaggaatt ccatttcaac
      721 cgctacctga cgcggcgccg ccgcatcgag atcgctcacg cgctctgcct cactgagcgc
      781 cagatcaaga tctggttcca gaatcggcgc atgaagtgga agaaagagca taaagatgag
      841 agccaggctc ccactgcagc cccggaagac gcggtgccct ccgtttccac agctgctgac
      901 aaggcggacg aggaggaaga ggaggaagag gaggaagaag aggaggaaga ggagtaaagg
      961 gccaggcaca ggaccctggc tgcacaggac agttggaaaa gcgtctttaa gagactcatt
     1021 gattttagtt acaaaaatgg ggggaaataa agtgtaaaaa aaaaaaagaa agaaagaaag
     1081 aaaaaagaaa gagaaaaaag aaagggaaag aaaaaaagag ggaatcagtt cctaccctca
     1141 ttccattcaa tcacccactt tagctcccag ggaaattagg tcaccttggg gaccctctct
     1201 gcctctgagg aacccagtag atacccacaa ccctgggcca gtgttgtgcg caggcacagc
     1261 caaaatacta cctagcacag gcctctttga gaggcactcc caaactacct atgggcccag
     1321 ccccagtggg ccaccattcc taagaagcct ccttcatgtc ccaacactgg cagacaccca
     1381 gcacctgccc cacccccatc acacacccgg ccaatacctg caaaccatga tcaatactac
     1441 ctactactag ccctaaacta cctattgtgt gctggctagc tcacctgctt ctcggtgccc
     1501 atccctccca ggctggacct tgatgcttct aactgatagt ctttggggtc accaaggctt
     1561 cactgacaag gcaatgaggt tcagggacca gggtattggc ttctatttaa attgaaaaat
     1621 aatatattta ttccaaagca taccaagtgc tgtaacctag aatccctctt tctctggctt
     1681 tgacacaagg tcagggccat taaccctact tcaggagggg agcattcccg agctggctgc
     1741 catcctctgg aatagctctg ggttttgttt ttgtgggact aaggagatgt tcccagactc
     1801 actgtcctct cccccttgct tttgtgtcct actgttcagc catgtcaaat atgtataccc
     1861 tgacttttcc tacaaggaca aatactgtat atttgaacca gatttttttt gtgttgttgt
     1921 catttctata atcttggagc tcatttgtaa aggaatgtct tgactttgga aggatgtttt
     1981 aatggggtga ctttgtagca tggtgtgttg tattgaacta attctgtagt gggtggggga
     2041 agtccagcac ccaccggggc catcatctcc cttgtctcct catgtcccgt cccacccccc
     2101 agcctggggt tcagagaagg cacgcttccc agcccagcta cctgtgtttt atgtaacaat
     2161 aaagatgctt ggtgacaaag aaa
//
