LOCUS       NP_034584                232 aa            linear   ROD 28-JAN-2025
DEFINITION  homeobox protein Hox-A6 [Mus musculus].
ACCESSION   NP_034584
VERSION     NP_034584.1
DBSOURCE    REFSEQ: accession NM_010454.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 232)
  AUTHORS   Frenette,B., Gueno,J., Houde,N., Landry-Truchon,K., Giguere,A.,
            Ashok,T., Ryckman,A., Morton,B.R., Mansfield,J.H. and Jeannotte,L.
  TITLE     Loss of Hoxa5 function affects Hox gene expression in different
            biological contexts
  JOURNAL   Sci Rep 14 (1), 30903 (2024)
   PUBMED   39730789
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 232)
  AUTHORS   Kumar,S., Alam,S.S., Bareke,E., Beauchamp,M.C., Dong,Y., Chan,W.,
            Majewski,J. and Jerome-Majewska,L.A.
  TITLE     Sf3b4 regulates chromatin remodeler splicing and Hox expression
  JOURNAL   Differentiation 131, 59-73 (2023)
   PUBMED   37167859
REFERENCE   3  (residues 1 to 232)
  AUTHORS   Catela,C., Chen,Y., Weng,Y., Wen,K. and Kratsios,P.
  TITLE     Control of spinal motor neuron terminal differentiation through
            sustained Hoxc8 gene activity
  JOURNAL   Elife 11, e70766 (2022)
   PUBMED   35315772
  REMARK    Publication Status: Online-Only
REFERENCE   4  (residues 1 to 232)
  AUTHORS   Yoshioka,K., Nagahisa,H., Miura,F., Araki,H., Kamei,Y.,
            Kitajima,Y., Seko,D., Nogami,J., Tsuchiya,Y., Okazaki,N.,
            Yonekura,A., Ohba,S., Sumita,Y., Chiba,K., Ito,K., Asahina,I.,
            Ogawa,Y., Ito,T., Ohkawa,Y. and Ono,Y.
  TITLE     Hoxa10 mediates positional memory to govern stem cell function in
            adult skeletal muscle
  JOURNAL   Sci Adv 7 (24) (2021)
   PUBMED   34108202
  REMARK    Publication Status: Online-Only
REFERENCE   5  (residues 1 to 232)
  AUTHORS   Lopez-Delgado,A.C., Delgado,I., Cadenas,V., Sanchez-Cabo,F. and
            Torres,M.
  TITLE     Axial skeleton anterior-posterior patterning is regulated through
            feedback regulation between Meis transcription factors and retinoic
            acid
  JOURNAL   Development 148 (1) (2021)
   PUBMED   33298461
  REMARK    Publication Status: Online-Only
REFERENCE   6  (residues 1 to 232)
  AUTHORS   Tkachuk,D.C., Kohler,S. and Cleary,M.L.
  TITLE     Involvement of a homolog of Drosophila trithorax by 11q23
            chromosomal translocations in acute leukemias
  JOURNAL   Cell 71 (4), 691-700 (1992)
   PUBMED   1423624
REFERENCE   7  (residues 1 to 232)
  AUTHORS   Scott,M.P.
  TITLE     Vertebrate homeobox gene nomenclature
  JOURNAL   Cell 71 (4), 551-553 (1992)
   PUBMED   1358459
REFERENCE   8  (residues 1 to 232)
  AUTHORS   Nazarali,A., Kim,Y. and Nirenberg,M.
  TITLE     Hox-1.11 and Hox-4.9 homeobox genes
  JOURNAL   Proc Natl Acad Sci U S A 89 (7), 2883-2887 (1992)
   PUBMED   1348361
REFERENCE   9  (residues 1 to 232)
  AUTHORS   Singh,G., Kaur,S., Stock,J.L., Jenkins,N.A., Gilbert,D.J.,
            Copeland,N.G. and Potter,S.S.
  TITLE     Identification of 10 murine homeobox genes
  JOURNAL   Proc Natl Acad Sci U S A 88 (23), 10706-10710 (1991)
   PUBMED   1683707
REFERENCE   10 (residues 1 to 232)
  AUTHORS   Gaunt,S.J., Coletta,P.L., Pravtcheva,D. and Sharpe,P.T.
  TITLE     Mouse Hox-3.4: homeobox sequence and embryonic expression patterns
            compared with other members of the Hox gene network
  JOURNAL   Development 109 (2), 329-339 (1990)
   PUBMED   1976088
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC119105.1, BQ558488.1 and AC015583.34.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC119105.1, ERR3363658.2578254.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..232
                     /organism="Mus musculus"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 25.4 cM"
     Protein         1..232
                     /product="homeobox protein Hox-A6"
                     /note="homeobox protein M5-4; homeobox protein Hox-1.2;
                     homeo box A6"
                     /calculated_mol_wt=26204
     Region          88..126
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (P09092.2)"
     Region          135..140
                     /region_name="Antp-type hexapeptide"
                     /note="propagated from UniProtKB/Swiss-Prot (P09092.2)"
     Region          155..211
                     /region_name="Homeodomain"
                     /note="pfam00046"
                     /db_xref="CDD:459649"
     CDS             1..232
                     /gene="Hoxa6"
                     /gene_synonym="Hox-1.2"
                     /coded_by="NM_010454.3:49..747"
                     /db_xref="CCDS:CCDS20144.1"
                     /db_xref="GeneID:15403"
                     /db_xref="MGI:MGI:96178"
ORIGIN      
        1 mssyfvnptf pgslpsgqds flgqlplypa gydalrpfpa sygasslpdk tytspcfyqq
       61 snsvlacnra syeygascfy sdkdlsgasp sgnnkqrgpg dylhfspeqq ykpdgsvqgk
      121 alheegtdrk ytspvypwmq rmnscagavy gshgrrgrqt ytryqtlele kefhfnrylt
      181 rrrrieiana lclterqiki wfqnrrmkwk kenklinstq asgedseaka ge
//
