LOCUS       NM_008264               1318 bp    mRNA    linear   ROD 18-MAR-2025
DEFINITION  Mus musculus homeobox A13 (Hoxa13), mRNA.
ACCESSION   NM_008264 XM_906397
VERSION     NM_008264.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1318)
  AUTHORS   Palacio,V., Pancho,A., Morabito,A., Malkmus,J., He,Z., Soussi,G.,
            Zeller,R., Treutlein,B. and Zuniga,A.
  TITLE     Single-cell profiling of penta- and tetradactyl mouse limb buds
            identifies mesenchymal progenitors controlling digit numbers and
            identities
  JOURNAL   Nat Commun 16 (1), 1226 (2025)
   PUBMED   39890843
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1318)
  AUTHORS   Chen,X., Tober,J., Dominguez,M., Tang,A.T., Bockman,J., Yang,J.,
            Mani,S., Lee,C.N., Chen,M., Thillaikumaran,T., Mericko-Ishizuka,P.,
            Mainigi,M., Speck,N.A. and Kahn,M.L.
  TITLE     Lineage tracing studies suggest that the placenta is not a de novo
            source of hematopoietic stem cells
  JOURNAL   PLoS Biol 23 (1), e3003003 (2025)
   PUBMED   39874373
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1318)
  AUTHORS   Frenette,B., Gueno,J., Houde,N., Landry-Truchon,K., Giguere,A.,
            Ashok,T., Ryckman,A., Morton,B.R., Mansfield,J.H. and Jeannotte,L.
  TITLE     Loss of Hoxa5 function affects Hox gene expression in different
            biological contexts
  JOURNAL   Sci Rep 14 (1), 30903 (2024)
   PUBMED   39730789
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1318)
  AUTHORS   Fuiten,A.M., Yoshimoto,Y., Shukunami,C. and Stadler,H.S.
  TITLE     Digits in a dish: An in vitro system to assess the molecular
            genetics of hand/foot development at single-cell resolution
  JOURNAL   Front Cell Dev Biol 11, 1135025 (2023)
   PUBMED   36994104
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 1318)
  AUTHORS   Chen,X., Tang,A.T., Tober,J., Yang,J., Leu,N.A., Sterling,S.,
            Chen,M., Yang,Y., Mericko-Ishizuka,P., Speck,N.A. and Kahn,M.L.
  TITLE     Mouse placenta fetal macrophages arise from endothelial cells
            outside the placenta
  JOURNAL   Dev Cell 57 (23), 2652-2660 (2022)
   PUBMED   36473461
REFERENCE   6  (bases 1 to 1318)
  AUTHORS   Scott,M.P.
  TITLE     Vertebrate homeobox gene nomenclature
  JOURNAL   Cell 71 (4), 551-553 (1992)
   PUBMED   1358459
REFERENCE   7  (bases 1 to 1318)
  AUTHORS   Mock,B.A., D'Hoostelaere,L.A., Matthai,R. and Huppi,K.
  TITLE     A mouse homeo box gene, Hox-1.5, and the morphological locus, Hd,
            map to within 1 cM on chromosome 6
  JOURNAL   Genetics 116 (4), 607-612 (1987)
   PUBMED   2887485
REFERENCE   8  (bases 1 to 1318)
  AUTHORS   Gibson,D.M. and MacLean,S.J.
  TITLE     Ef2: a new LY-3-linked light-chain marker expressed in normal mouse
            serum immunoglobulin
  JOURNAL   J Exp Med 149 (6), 1477-1486 (1979)
   PUBMED   109570
REFERENCE   9  (bases 1 to 1318)
  AUTHORS   Eicher,E.M. and Beamer,W.G.
  TITLE     Inherited ateliotic dwarfism in mice. Characteristics of the
            mutation, little, on chromosome 6
  JOURNAL   J Hered 67 (2), 87-91 (1976)
   PUBMED   1270792
REFERENCE   10 (bases 1 to 1318)
  AUTHORS   Green,M.C. and Shultz,L.D.
  TITLE     Motheaten, an immunodeficient mutant of the mouse. I. Genetics and
            pathology
  JOURNAL   J Hered 66 (5), 250-258 (1975)
   PUBMED   1184950
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            U59322.1.
            
            On Dec 7, 2005 this sequence version replaced XM_906397.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849381,
                              SAMN00849382 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on single protein-coding
                                         transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1318
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 25.41 cM"
     gene            1..1318
                     /gene="Hoxa13"
                     /gene_synonym="Hd; Hox-1.10"
                     /note="homeobox A13"
                     /db_xref="GeneID:15398"
                     /db_xref="MGI:MGI:96173"
     exon            1..1022
                     /gene="Hoxa13"
                     /gene_synonym="Hd; Hox-1.10"
                     /inference="alignment:Splign:2.1.0"
     CDS             107..1267
                     /gene="Hoxa13"
                     /gene_synonym="Hd; Hox-1.10"
                     /note="homeobox protein Hox-1.10; hypodactyly"
                     /codon_start=1
                     /product="homeobox protein Hox-A13"
                     /protein_id="NP_032290.1"
                     /db_xref="GeneID:15398"
                     /db_xref="MGI:MGI:96173"
                     /translation="MTASVLLHPRWIEPTVMFLYDNGGGLVADELNKNMEGAAAAAAA
                     AAAAAAAGAGGGGFPHPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAA
                     AAYSSAPGEAPPSAAAAAAAAAAAAAAAAAASSSGGPGPAGPAGAEAAKQCSPCSAAA
                     QSSSGPAALPYGYFGSGYYPCARMGPHPNAIKSCAQPASAAAAFADKYMDTAGPAAEE
                     FSSRAKEFAFYHQGYAAGPYHHHQPVPGYLDMPVVPGLGGPGESRHEPLGLPMESYQP
                     WALPNGWNGQMYCPKEQTQPPHLWKSTLPDVVSHPSDASSYRRGRKKRVPYTKVQLKE
                     LEREYATNKFITKDKRRRISATTNLSERQVTIWFQNRRVKEKKVINKLKTTS"
     exon            1023..1318
                     /gene="Hoxa13"
                     /gene_synonym="Hd; Hox-1.10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgacccgccc ccctcgctcg ggccccggcc ccgcgcgccg cgctcttcac ttcttggggg
       61 ctttttaaaa cagcgccact ggggtcttct ccatgcggct cgggctatga cagcctccgt
      121 gctcctccac ccccgctgga tcgagcccac cgtcatgttt ctctacgaca acggcggcgg
      181 cctggtggcc gacgagctca acaagaacat ggaaggggcg gcggcggcgg cagcggcggc
      241 ggccgcggcg gcggcggcgg gagctggggg cgggggcttc ccccacccgg ctgccgcggc
      301 cgcggggggc aacttctcgg tggccgcagc ggccgccgcc gccgccgccg ccgcggccaa
      361 ccagtgccgc aacctgatgg cgcatcccgc acccctggcg cccggcgccg cggccgcgta
      421 cagcagcgcc ccgggggagg cgcccccgtc cgccgccgcc gccgccgccg ccgccgctgc
      481 tgccgccgcc gccgcggctg ccgcgtcgtc gtcgggaggg cccgggccgg cggggcccgc
      541 gggtgccgag gccgccaagc agtgcagtcc ctgctcggcg gcggcacaga gctcgtcggg
      601 gcccgcggcg ctgccctacg gctacttcgg cagcggctac tacccgtgcg cccgcatggg
      661 cccgcacccc aacgccatca agtcgtgcgc gcagcctgct tcggccgccg ccgccttcgc
      721 cgacaagtac atggacaccg ccggccccgc ggccgaggag ttcagctccc gcgccaagga
      781 gtttgctttc taccatcagg gctacgcagc cgggccttac caccatcacc agcccgtgcc
      841 cggctacctg gatatgccag tagttccggg gctcgggggt cctggcgagt cgcgccacga
      901 gcctctgggg cttcccatgg aaagctatca gccctgggct ctgcccaacg gctggaacgg
      961 ccaaatgtac tgccccaaag agcagacgca gcctccccac ctctggaagt ccactctgcc
     1021 cgacgtcgtc tcccatcctt cagacgccag ctcctatagg agggggagaa agaagcgcgt
     1081 gccttacact aaggtgcagt tgaaagaact cgaacgggaa tacgctacga acaaattcat
     1141 taccaaggac aaacggagga ggatatcagc cacgacaaac ctctctgaga ggcaggtcac
     1201 aatctggttc cagaacagga gggtcaaaga gaaaaaagtc atcaataaac tcaagaccac
     1261 tagttaatgg attaaaaggt ggagcagagg gcagcttgaa gaaacgctta aggatttg
//
