LOCUS       NM_001347487            2217 bp    mRNA    linear   ROD 04-FEB-2025
DEFINITION  Mus musculus heterogeneous nuclear ribonucleoprotein H1 (Hnrnph1),
            transcript variant 1, mRNA.
ACCESSION   NM_001347487 XM_006533875
VERSION     NM_001347487.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2217)
  AUTHORS   Shen,C.L., Tsai,Y.Y., Chou,S.J., Chang,Y.M. and Tarn,W.Y.
  TITLE     RBM4-mediated intron excision of Hsf1 induces BDNF for cerebellar
            foliation
  JOURNAL   Commun Biol 7 (1), 1712 (2024)
   PUBMED   39738787
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2217)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 2217)
  AUTHORS   Korff,A., Yang,X., O'Donovan,K., Gonzalez,A., Teubner,B.J.,
            Nakamura,H., Messing,J., Yang,F., Carisey,A.F., Wang,Y.D.,
            Patni,T., Sheppard,H., Zakharenko,S.S., Chook,Y.M., Taylor,J.P. and
            Kim,H.J.
  TITLE     A murine model of hnRNPH2-related neurodevelopmental disorder
            reveals a mechanism for genetic compensation by Hnrnph1
  JOURNAL   J Clin Invest 133 (14), e160309 (2023)
   PUBMED   37463454
  REMARK    GeneRIF: A murine model of hnRNPH2-related neurodevelopmental
            disorder reveals a mechanism for genetic compensation by Hnrnph1.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2217)
  AUTHORS   Feng,S., Wen,H., Liu,K., Xiong,M., Li,J., Gui,Y., Lv,C., Zhang,J.,
            Ma,X., Wang,X. and Yuan,S.
  TITLE     hnRNPH1 establishes Sertoli-germ cell crosstalk through cooperation
            with PTBP1 and AR, and is essential for male fertility in mice
  JOURNAL   Development 150 (3) (2023)
   PUBMED   36718792
  REMARK    GeneRIF: hnRNPH1 establishes Sertoli-germ cell crosstalk through
            cooperation with PTBP1 and AR, and is essential for male fertility
            in mice.
REFERENCE   5  (bases 1 to 2217)
  AUTHORS   Luo,Z., Xia,M., Shi,W., Zhao,C., Wang,J., Xin,D., Dong,X.,
            Xiong,Y., Zhang,F., Berry,K., Ogurek,S., Liu,X., Rao,R., Xing,R.,
            Wu,L.M.N., Cui,S., Xu,L., Lin,Y., Ma,W., Tian,S., Xie,Q., Zhang,L.,
            Xin,M., Wang,X., Yue,F., Zheng,H., Liu,Y., Stevenson,C.B., de
            Blank,P., Perentesis,J.P., Gilbertson,R.J., Li,H., Ma,J., Zhou,W.,
            Taylor,M.D. and Lu,Q.R.
  TITLE     Human fetal cerebellar cell atlas informs medulloblastoma origin
            and oncogenesis
  JOURNAL   Nature 612 (7941), 787-794 (2022)
   PUBMED   36450980
REFERENCE   6  (bases 1 to 2217)
  AUTHORS   Jensen,P., Magdaleno,S., Lehman,K.M., Rice,D.S., Lavallie,E.R.,
            Collins-Racie,L., McCoy,J.M. and Curran,T.
  TITLE     A neurogenomics approach to gene expression analysis in the
            developing brain
  JOURNAL   Brain Res Mol Brain Res 132 (2), 116-127 (2004)
   PUBMED   15582152
REFERENCE   7  (bases 1 to 2217)
  AUTHORS   Shu,H., Chen,S., Bi,Q., Mumby,M. and Brekken,D.L.
  TITLE     Identification of phosphoproteins and their phosphorylation sites
            in the WEHI-231 B lymphoma cell line
  JOURNAL   Mol Cell Proteomics 3 (3), 279-286 (2004)
   PUBMED   14729942
REFERENCE   8  (bases 1 to 2217)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   9  (bases 1 to 2217)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 2217)
  AUTHORS   Liu,J., Beqaj,S., Yang,Y., Honore,B. and Schuger,L.
  TITLE     Heterogeneous nuclear ribonucleoprotein-H plays a suppressive role
            in visceral myogenesis
  JOURNAL   Mech Dev 104 (1-2), 79-87 (2001)
   PUBMED   11404082
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL645904.13, BY787002.1, BY307937.1, CO426010.1, DV657681.1,
            AK165283.1 and AA124353.1.
            
            On Apr 20, 2018 this sequence version replaced NM_001347487.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK088169.1, SRR7345562.3591794.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-41                AL645904.13        23304-23344
            42-92               BY787002.1         1-51
            93-465              BY307937.1         3-375
            466-1097            CO426010.1         1-632
            1098-1779           DV657681.1         1-682
            1780-2215           AK165283.1         1134-1569
            2216-2217           AA124353.1         323-324
FEATURES             Location/Qualifiers
     source          1..2217
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 30.56 cM"
     gene            1..2217
                     /gene="Hnrnph1"
                     /gene_synonym="E430005G16Rik; Hnrnph; Hnrph1"
                     /note="heterogeneous nuclear ribonucleoprotein H1"
                     /db_xref="GeneID:59013"
                     /db_xref="MGI:MGI:1891925"
     exon            1..125
                     /gene="Hnrnph1"
                     /gene_synonym="E430005G16Rik; Hnrnph; Hnrph1"
                     /inference="alignment:Splign:2.1.0"
     exon            126..262
                     /gene="Hnrnph1"
                     /gene_synonym="E430005G16Rik; Hnrnph; Hnrph1"
                     /inference="alignment:Splign:2.1.0"
     CDS             166..1584
                     /gene="Hnrnph1"
                     /gene_synonym="E430005G16Rik; Hnrnph; Hnrph1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     heterogeneous nuclear ribonucleoprotein H"
                     /codon_start=1
                     /product="heterogeneous nuclear ribonucleoprotein H
                     isoform 1"
                     /protein_id="NP_001334416.1"
                     /db_xref="CCDS:CCDS83800.1"
                     /db_xref="GeneID:59013"
                     /db_xref="MGI:MGI:1891925"
                     /translation="MMLGAEGGEGFVVKVRGLPWSCSADEVQRFFSDCKIQNGAQGIR
                     FIYTREGRPSGEAFVELESEDEVKLALKKDRETMGHRYVEVFKSNNVEMDWVLKHTGP
                     NSPDTANDGFVRLRGLPFGCSKEEIVQFFSGLEIVPNGITLPVDFQGRSTGEAFVQFA
                     SQEIAEKALKKHKERIGHRYIEIFKSSRAEVRTHYDPPRKLMAMQRPGPYDRPGAGRG
                     YNSIGRGAGFERMRRGAYGGGYGGYDDYNGYNDGYGFGSDRFGRDLNYCFSGMSDHRY
                     GDGGSTFQSTTGHCVHMRGLPYRATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVE
                     FATHEDAVAAMSKDKANMQHRYVELFLNSTAGASGGAYEHRYVELFLNSTAGASGGAY
                     GSQMMGGMGLSNQSSYGGPASQQLSGGYGGGYGGQSSMSGYGSQGAVNSSYYSNGSRA
                     SMGVNGMGGMSSMSSMSGGWGM"
     exon            263..418
                     /gene="Hnrnph1"
                     /gene_synonym="E430005G16Rik; Hnrnph; Hnrph1"
                     /inference="alignment:Splign:2.1.0"
     exon            419..562
                     /gene="Hnrnph1"
                     /gene_synonym="E430005G16Rik; Hnrnph; Hnrph1"
                     /inference="alignment:Splign:2.1.0"
     exon            563..701
                     /gene="Hnrnph1"
                     /gene_synonym="E430005G16Rik; Hnrnph; Hnrph1"
                     /inference="alignment:Splign:2.1.0"
     exon            702..880
                     /gene="Hnrnph1"
                     /gene_synonym="E430005G16Rik; Hnrnph; Hnrph1"
                     /inference="alignment:Splign:2.1.0"
     exon            881..952
                     /gene="Hnrnph1"
                     /gene_synonym="E430005G16Rik; Hnrnph; Hnrph1"
                     /inference="alignment:Splign:2.1.0"
     exon            953..1086
                     /gene="Hnrnph1"
                     /gene_synonym="E430005G16Rik; Hnrnph; Hnrph1"
                     /inference="alignment:Splign:2.1.0"
     exon            1087..1222
                     /gene="Hnrnph1"
                     /gene_synonym="E430005G16Rik; Hnrnph; Hnrph1"
                     /inference="alignment:Splign:2.1.0"
     exon            1223..1282
                     /gene="Hnrnph1"
                     /gene_synonym="E430005G16Rik; Hnrnph; Hnrph1"
                     /inference="alignment:Splign:2.1.0"
     exon            1283..1372
                     /gene="Hnrnph1"
                     /gene_synonym="E430005G16Rik; Hnrnph; Hnrph1"
                     /inference="alignment:Splign:2.1.0"
     exon            1373..1465
                     /gene="Hnrnph1"
                     /gene_synonym="E430005G16Rik; Hnrnph; Hnrph1"
                     /inference="alignment:Splign:2.1.0"
     exon            1466..2217
                     /gene="Hnrnph1"
                     /gene_synonym="E430005G16Rik; Hnrnph; Hnrph1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacgcaagtg gggcggggcc ggcaacaggg tgcgcgtgcg cagagcttgc tggaagggct
       61 ttatttagcc tgcgcaggcg cccgcttatc atttctcctc agccacgccg aggctttttg
      121 tggagccccg caatctgtgt ggacgccagg accaccgaag ggacgatgat gctgggagca
      181 gaaggcggag agggcttcgt ggtgaaggtc cggggcttgc cctggtcctg ctccgcggat
      241 gaagtgcagc gctttttttc tgactgcaaa attcaaaatg gggctcaagg tattcgtttc
      301 atctacacca gagaaggcag accaagtggc gaggcttttg ttgaacttga atcagaagat
      361 gaagtcaaat tggccttgaa aaaagacaga gaaactatgg gacacagata tgttgaagta
      421 ttcaagtcaa acaacgttga aatggattgg gtgttgaagc atactggtcc aaatagtcct
      481 gacacagcca atgatggctt tgtacggctt agaggactcc cttttggatg tagcaaggaa
      541 gaaattgttc agttcttctc agggttggaa atcgtgccaa atgggataac attgccggtg
      601 gacttccagg ggaggagtac gggggaggcc ttcgtgcagt ttgcttcaca ggaaatagct
      661 gaaaaggctc taaagaaaca caaggaaaga atagggcaca ggtatattga aatatttaag
      721 agcagtcgag ctgaagttag aactcattat gacccaccac gaaaacttat ggccatgcag
      781 cggccaggtc cctatgacag acctggggct ggcagagggt ataacagcat tggcagagga
      841 gctggttttg agaggatgag gcgtggtgct tatggtggag gctatggagg ctatgatgat
      901 tataatggct ataatgatgg ctatggattt ggttcagata gatttggaag agacctcaat
      961 tattgttttt caggaatgtc tgaccacaga tatggggacg gtggctctac tttccagagt
     1021 acaaccggac actgtgtaca catgcgggga ttaccataca gagctactga gaatgacatt
     1081 tataattttt tttcaccact caaccctgtg agagtacata ttgagattgg acctgatggc
     1141 agagtaactg gtgaagcaga tgttgagttc gcaacccatg aagatgctgt tgcagctatg
     1201 tcaaaagata aagcaaatat gcaacacaga tatgtagagc tcttcttgaa ttctacagca
     1261 ggagcaagcg gtggtgctta cgaacacaga tatgtagaac tcttcttgaa ttctacagca
     1321 ggagcaagcg gtggtgctta tggtagccaa atgatgggag gcatgggctt gtcaaaccag
     1381 tccagttacg gtggcccagc cagccagcag ctgagtggtg gttatggagg tggttacggt
     1441 ggccagagca gcatgagcgg atatggtagc caaggagcag tgaacagcag ctactacagt
     1501 aatggaagcc gagcatctat gggcgtgaat ggaatgggag ggatgtctag catgtctagt
     1561 atgagtggtg gatggggaat gtaattgatt ttgatcactg actcttggtc aaaaagaaat
     1621 tttttaaaaa acccctcagt ttaacagatt ttgcaatcca tccagccttg tggttttatg
     1681 cctgctctta agtgaacatt ggcgtcgctc aaagaaggct caatgttgag catagcagtc
     1741 acctaggatg atagagcaaa gctgagtgaa ctgtaactgt taaacttaat tcctagcttt
     1801 tctctagtta ctgtaggatg tacgtaagca gtaagtgtat ttaggttaaa gcagttgaat
     1861 tatgttaaat gttgctctta tacatacatt gaacactgtt gatgcatgtt gaaaaacatg
     1921 cttttttgta aaactatagg agctgcgtct acaattaaag tgatacattt ggcatgtttg
     1981 ttaattctaa atttatttga taacctgtaa ggcacgtgag tttaaagctc ttttttttta
     2041 tttttaagtt aatggagaag ttttgagaga caataccatt attttttagg atttttggtc
     2101 ttagtgtttg tatgaaattc tgaggccttg atttaagtct ttcattgtat tgtgatttct
     2161 ttttaggtgt attgcgctaa gtgaaccttg tcaaataaat cttcctttta aaagcta
//
