LOCUS       NM_133834               2179 bp    mRNA    linear   ROD 24-APR-2024
DEFINITION  Mus musculus heterogeneous nuclear ribonucleoprotein F (Hnrnpf),
            transcript variant 1, mRNA.
ACCESSION   NM_133834
VERSION     NM_133834.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2179)
  AUTHORS   Liao,M.C., Lo,C.S., Pang,Y.C., Yang,W.X., Su,K., Zhao,X.P.,
            Miyata,K.N., Peng,J., Ingelfinger,J.R., Chan,J.S.D. and Zhang,S.L.
  TITLE     Heterogeneous nuclear ribonucleoprotein F deficiency in mouse
            podocyte promotes podocytopathy mediated by methyltransferase-like
            14 nuclear translocation resulting in Sirtuin 1 gene inhibition
  JOURNAL   Transl Res 267, 1-9 (2024)
   PUBMED   38195017
  REMARK    GeneRIF: Heterogeneous nuclear ribonucleoprotein F deficiency in
            mouse podocyte promotes podocytopathy mediated by
            methyltransferase-like 14 nuclear translocation resulting in
            Sirtuin 1 gene inhibition.
REFERENCE   2  (bases 1 to 2179)
  AUTHORS   Korff,A., Yang,X., O'Donovan,K., Gonzalez,A., Teubner,B.J.,
            Nakamura,H., Messing,J., Yang,F., Carisey,A.F., Wang,Y.D.,
            Patni,T., Sheppard,H., Zakharenko,S.S., Chook,Y.M., Taylor,J.P. and
            Kim,H.J.
  TITLE     A murine model of hnRNPH2-related neurodevelopmental disorder
            reveals a mechanism for genetic compensation by Hnrnph1
  JOURNAL   J Clin Invest 133 (14), e160309 (2023)
   PUBMED   37463454
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2179)
  AUTHORS   Feng,S., Li,J., Wen,H., Liu,K., Gui,Y., Wen,Y., Wang,X. and Yuan,S.
  TITLE     hnRNPH1 recruits PTBP2 and SRSF3 to modulate alternative splicing
            in germ cells
  JOURNAL   Nat Commun 13 (1), 3588 (2022)
   PUBMED   35739118
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2179)
  AUTHORS   Norrie,J.L., Lupo,M.S., Xu,B., Al Diri,I., Valentine,M., Putnam,D.,
            Griffiths,L., Zhang,J., Johnson,D., Easton,J., Shao,Y., Honnell,V.,
            Frase,S., Miller,S., Stewart,V., Zhou,X., Chen,X. and Dyer,M.A.
  TITLE     Nucleome Dynamics during Retinal Development
  JOURNAL   Neuron 104 (3), 512-528 (2019)
   PUBMED   31493975
REFERENCE   5  (bases 1 to 2179)
  AUTHORS   Lo,C.S., Miyata,K.N., Zhao,S., Ghosh,A., Chang,S.Y., Chenier,I.,
            Filep,J.G., Ingelfinger,J.R., Zhang,S.L. and Chan,J.S.D.
  TITLE     Tubular Deficiency of Heterogeneous Nuclear Ribonucleoprotein F
            Elevates Systolic Blood Pressure and Induces Glycosuria in Mice
  JOURNAL   Sci Rep 9 (1), 15765 (2019)
   PUBMED   31673025
  REMARK    GeneRIF: Tubular Deficiency of Heterogeneous Nuclear
            Ribonucleoprotein F Elevates Systolic Blood Pressure and Induces
            Glycosuria in Mice.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2179)
  AUTHORS   Sultana,D.A., Tomita,S., Hamada,M., Iwanaga,Y., Kitahama,Y.,
            Khang,N.V., Hirai,S., Ohigashi,I., Nitta,S., Amagai,T.,
            Takahashi,S. and Takahama,Y.
  TITLE     Gene expression profile of the third pharyngeal pouch reveals role
            of mesenchymal MafB in embryonic thymus development
  JOURNAL   Blood 113 (13), 2976-2987 (2009)
   PUBMED   19164599
REFERENCE   7  (bases 1 to 2179)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   8  (bases 1 to 2179)
  AUTHORS   Carninci,P., Waki,K., Shiraki,T., Konno,H., Shibata,K., Itoh,M.,
            Aizawa,K., Arakawa,T., Ishii,Y., Sasaki,D., Bono,H., Kondo,S.,
            Sugahara,Y., Saito,R., Osato,N., Fukuda,S., Sato,K., Watahiki,A.,
            Hirozane-Kishikawa,T., Nakamura,M., Shibata,Y., Yasunishi,A.,
            Kikuchi,N., Yoshiki,A., Kusakabe,M., Gustincich,S., Beisel,K.,
            Pavan,W., Aidinis,V., Nakagawara,A., Held,W.A., Iwata,H., Kono,T.,
            Nakauchi,H., Lyons,P., Wells,C., Hume,D.A., Fagiolini,M.,
            Hensch,T.K., Brinkmeier,M., Camper,S., Hirota,J., Mombaerts,P.,
            Muramatsu,M., Okazaki,Y., Kawai,J. and Hayashizaki,Y.
  TITLE     Targeting a complex transcriptome: the construction of the mouse
            full-length cDNA encyclopedia
  JOURNAL   Genome Res 13 (6B), 1273-1289 (2003)
   PUBMED   12819125
REFERENCE   9  (bases 1 to 2179)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   10 (bases 1 to 2179)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ048596.1, AK076478.1, BC047346.1 and CX218091.1.
            
            On Oct 23, 2009 this sequence version replaced NM_133834.1.
            
            Transcript Variant: This variant (1) represents the shortest
            transcript. Variants 1-7 encode the same protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC032197.1, AK076478.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-53                CJ048596.1         4-56
            54-1543             AK076478.1         12-1501
            1544-2157           BC047346.1         1785-2398
            2158-2179           CX218091.1         395-416
FEATURES             Location/Qualifiers
     source          1..2179
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 55.66 cM"
     gene            1..2179
                     /gene="Hnrnpf"
                     /gene_synonym="4833420I20Rik; Hnrpf"
                     /note="heterogeneous nuclear ribonucleoprotein F"
                     /db_xref="GeneID:98758"
                     /db_xref="MGI:MGI:2138741"
     exon            1..58
                     /gene="Hnrnpf"
                     /gene_synonym="4833420I20Rik; Hnrpf"
                     /inference="alignment:Splign:2.1.0"
     exon            59..187
                     /gene="Hnrnpf"
                     /gene_synonym="4833420I20Rik; Hnrpf"
                     /inference="alignment:Splign:2.1.0"
     exon            188..248
                     /gene="Hnrnpf"
                     /gene_synonym="4833420I20Rik; Hnrpf"
                     /inference="alignment:Splign:2.1.0"
     exon            249..2163
                     /gene="Hnrnpf"
                     /gene_synonym="4833420I20Rik; Hnrpf"
                     /inference="alignment:Splign:2.1.0"
     CDS             298..1545
                     /gene="Hnrnpf"
                     /gene_synonym="4833420I20Rik; Hnrpf"
                     /note="hnRNP F"
                     /codon_start=1
                     /product="heterogeneous nuclear ribonucleoprotein F"
                     /protein_id="NP_598595.1"
                     /db_xref="CCDS:CCDS20467.1"
                     /db_xref="GeneID:98758"
                     /db_xref="MGI:MGI:2138741"
                     /translation="MMLGPEGGEGYVVKLRGLPWSCSIEDVQNFLSDCTIHDGVAGVH
                     FIYTREGRQSGEAFVELESEDDVKLALKKDRESMGHRYIEVFKSHRTEMDWVLKHSGP
                     NSADSANDGFVRLRGLPFGCTKEEIVQFFSGLEIVPNGITLPVDPEGKITGEAFVQFA
                     SQELAEKALGKHKERIGHRYIEVFKSSQEEVRSYSDPPLKFMSVQRPGPYDRPGTARR
                     YIGIVKQAGLDRMRSGAYSAGYGGYEEYSGLSDGYGFTTDLFGRDLSYCLSGMYDHRY
                     GDSEFTVQSTTGHCVHMRGLPYKATENDIYNFFSPLNPVRVHIEIGPDGRVTGEADVE
                     FATHEEAVAAMSKDRANMQHRYIELFLNSTTGASNGAYSSQVMQGMGVSAAQATYSGL
                     ESQSVSGCYGAGYSGQNSMGGYD"
ORIGIN      
        1 cgtcttgcat ccttccggct ccgtcgtgga aggaggactg cgcctcgtct tcctgaaggt
       61 tgagaacaaa aagatgcacc tggactttcc ccggagccct ctgcgttttt aaggcgtcgg
      121 gtggagtttg agttcgtaag ccgcgttcct tactgaatat agaagtcact tctaccttcc
      181 tcccctggaa aacttgttac cttccattaa gtgtttccta cagaaggcat ctgtggtggt
      241 tctttaagct acaaaaaatt gcccaagctt gtgtgacatc agccctgtca agtgtccatg
      301 atgctgggcc ctgagggagg tgaaggctat gtggtcaaac tccgtggcct accctggtcc
      361 tgctcaattg aggacgtaca aaacttcctc tccgactgca caattcatga tggggtcgca
      421 ggtgttcatt tcatttatac tagagaaggc aggcagagtg gtgaggcttt tgttgaactt
      481 gagtcagaag atgatgtaaa attggctctg aaaaaagaca gggaaagcat gggacaccgg
      541 tatattgagg tgttcaagtc acacagaacc gagatggatt gggtgttgaa gcacagtggt
      601 ccaaacagcg ccgacagtgc caatgatggc tttgtgaggc ttcggggact cccatttgga
      661 tgcacaaagg aagaaatcgt tcagttcttc tcagggttgg aaattgtgcc aaacgggatc
      721 acactacctg tggacccgga aggcaagatt acaggggagg ccttcgttca gtttgcctca
      781 caagagttag ctgagaaagc tttagggaag cacaaggaga gaatagggca caggtatatt
      841 gaagtgttta agagcagtca ggaggaagtt agatcatact cagatccacc tctgaagttt
      901 atgtctgtgc aaaggcctgg gccttatgac aggcctggca cagcccggag gtacattggc
      961 attgtgaaac aggcaggtct ggataggatg aggtctggtg cctatagtgc aggctatggg
     1021 ggctatgaag aatacagtgg cctcagtgat ggctatggct tcaccactga cctgtttggg
     1081 agagacctca gctattgtct ctcaggaatg tatgaccaca gatatggaga cagcgagttc
     1141 acagtgcaga gcaccaccgg ccactgcgtc cacatgagag ggctgcccta caaagcaacg
     1201 gagaacgaca tttacaactt cttctctcca ctcaaccctg tgagagttca tattgagatt
     1261 ggtcctgatg gaagagtgac gggagaagct gatgttgagt ttgctactca tgaagaagca
     1321 gtggcagcta tgtccaagga cagggccaac atgcagcaca gatacataga actcttcctg
     1381 aattcaacaa caggggctag caatggggct tatagcagcc aggtgatgca gggcatgggc
     1441 gtgtcagctg cccaggcaac ttacagtggc ctggagagcc agtcagtgag tggctgttac
     1501 ggggccggct acagcggtca gaacagcatg ggcggatatg attagtattg taggaacatt
     1561 tgagttattt caatcagaaa atttcacagg cagccaataa gcagtcaaga gcagtttata
     1621 actctagagg aagctggggg acccactttg caccatgagt ttgtgaaatc tggattaaaa
     1681 aattacctct tcagtgtttc tcatgcaaac ttttcttcta gcatgtaata ttgagtaaac
     1741 taaaactatt ttcttccgct tttctcaatt aacatttttg gtagtatact taagagtgat
     1801 gttatctgag ttaagtagtt taagtatgtt gagtggatct ttaagcacac cacagtgaac
     1861 acactgggga tatgtacttt tctggagaac ccaaaggtgc tagatccctg atgcaaaaga
     1921 gaagcatttc tcatgttcat tctagttata ttttcattta aaatctttag gttaagttta
     1981 agctttttaa aagttagttt tgagaattga gacacaatac taatactgta ggaattggtg
     2041 aggccttgac ttaaagcttt ctttgtactg tgatttcctt ttgggtgtat tttgctaagt
     2101 gaaacttgtt aaattttttg ttaactaaat ttttttctta aaataaagac tttttcacaa
     2161 tgaaaaaaaa aaaaaaaaa
//
