LOCUS       NM_001077265            6811 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus heterogeneous nuclear ribonucleoprotein D (Hnrnpd),
            transcript variant 1, mRNA.
ACCESSION   NM_001077265
VERSION     NM_001077265.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6811)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6811)
  AUTHORS   Takada,Y., Fierro,L., Sato,K., Sanada,T., Ishii,A., Yamamoto,T. and
            Kotani,T.
  TITLE     Mature mRNA processing that deletes 3' end sequences directs
            translational activation and embryonic development
  JOURNAL   Sci Adv 9 (47), eadg6532 (2023)
   PUBMED   38000026
REFERENCE   3  (bases 1 to 6811)
  AUTHORS   Kattan,F.G., Koukouraki,P., Anagnostopoulos,A.K., Tsangaris,G.T.
            and Doxakis,E.
  TITLE     RNA binding protein AUF1/HNRNPD regulates nuclear export, stability
            and translation of SNCA transcripts
  JOURNAL   Open Biol 13 (11), 230158 (2023)
   PUBMED   37989221
  REMARK    GeneRIF: RNA binding protein AUF1/HNRNPD regulates nuclear export,
            stability and translation of SNCA transcripts.
REFERENCE   4  (bases 1 to 6811)
  AUTHORS   Das,O., Kundu,J., Ghosh,A., Gautam,A., Ghosh,S., Chakraborty,M.,
            Masid,A., Gauri,S.S., Mitra,D., Dutta,M., Mukherjee,B., Sinha,S.
            and Bhaumik,M.
  TITLE     AUF-1 knockdown in mice undermines gut microbial butyrate-driven
            hypocholesterolemia through AUF-1-Dicer-1-mir-122 hierarchy
  JOURNAL   Front Cell Infect Microbiol 12, 1011386 (2022)
   PUBMED   36601302
  REMARK    GeneRIF: AUF-1 knockdown in mice undermines gut microbial
            butyrate-driven hypocholesterolemia through AUF-1-Dicer-1-mir-122
            hierarchy.
            Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6811)
  AUTHORS   Wang,Y., Chen,D., Xie,H., Jia,M., Sun,X., Peng,F., Guo,F. and
            Tang,D.
  TITLE     AUF1 protects against ferroptosis to alleviate sepsis-induced acute
            lung injury by regulating NRF2 and ATF3
  JOURNAL   Cell Mol Life Sci 79 (5), 228 (2022)
   PUBMED   35391558
  REMARK    GeneRIF: AUF1 protects against ferroptosis to alleviate
            sepsis-induced acute lung injury by regulating NRF2 and ATF3.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6811)
  AUTHORS   Yasuda,S., Wada,S., Arao,Y., Kogawa,M., Kayama,F. and Katayama,S.
  TITLE     Interaction between 3' untranslated region of calcitonin receptor
            messenger ribonucleic acid (RNA) and adenylate/uridylate (AU)-rich
            element binding proteins (AU-rich RNA-binding factor 1 and Hu
            antigen R)
  JOURNAL   Endocrinology 145 (4), 1730-1738 (2004)
   PUBMED   14715706
  REMARK    GeneRIF: AUF1 p40, HuR, and the 3'UTR of the CTR mRNA transcript
            could be involved in posttranscriptional regulation of CTR mRNA
            expression.
REFERENCE   7  (bases 1 to 6811)
  AUTHORS   Pioli,P.A., Hamilton,B.J., Connolly,J.E., Brewer,G. and Rigby,W.F.
  TITLE     Lactate dehydrogenase is an AU-rich element-binding protein that
            directly interacts with AUF1
  JOURNAL   J Biol Chem 277 (38), 35738-35745 (2002)
   PUBMED   12107167
  REMARK    GeneRIF: interaction with lactate dehydrogenase
REFERENCE   8  (bases 1 to 6811)
  AUTHORS   Gouble,A., Grazide,S., Meggetto,F., Mercier,P., Delsol,G. and
            Morello,D.
  TITLE     A new player in oncogenesis: AUF1/hnRNPD overexpression leads to
            tumorigenesis in transgenic mice
  JOURNAL   Cancer Res 62 (5), 1489-1495 (2002)
   PUBMED   11888925
REFERENCE   9  (bases 1 to 6811)
  AUTHORS   Gouble,A. and Morello,D.
  TITLE     Synchronous and regulated expression of two AU-binding proteins,
            AUF1 and HuR, throughout murine development
  JOURNAL   Oncogene 19 (47), 5377-5384 (2000)
   PUBMED   11103939
REFERENCE   10 (bases 1 to 6811)
  AUTHORS   Ehrenman,K., Long,L., Wagner,B.J. and Brewer,G.
  TITLE     Characterization of cDNAs encoding the murine A+U-rich RNA-binding
            protein AUF1
  JOURNAL   Gene 149 (2), 315-319 (1994)
   PUBMED   7959009
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC049098.1, CX567003.1 and AC022062.10.
            
            On Sep 28, 2013 this sequence version replaced NM_001077265.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR10223970.7666.1, BC011172.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849380, SAMN00849383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1167              BC049098.1         1-1167
            1168-1736           CX567003.1         143-711
            1737-6811           AC022062.10        20606-25680
FEATURES             Location/Qualifiers
     source          1..6811
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 48.46 cM"
     gene            1..6811
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /note="heterogeneous nuclear ribonucleoprotein D"
                     /db_xref="GeneID:11991"
                     /db_xref="MGI:MGI:101947"
     exon            1..547
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /inference="alignment:Splign:2.1.0"
     CDS             315..1382
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /note="isoform a is encoded by transcript variant 1;
                     heterogeneous nuclear ribonucleoprotein D0; hnRNP D0;
                     AU-rich element RNA-binding protein 1"
                     /codon_start=1
                     /product="heterogeneous nuclear ribonucleoprotein D0
                     isoform a"
                     /protein_id="NP_001070733.1"
                     /db_xref="CCDS:CCDS39182.1"
                     /db_xref="GeneID:11991"
                     /db_xref="MGI:MGI:101947"
                     /translation="MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAAAAQGPAAAAGS
                     GSGGGGSAAGGTEGGSAEAEGAKIDASKNEEDEGHSNSSPRHTEAAAAQREEWKMFIG
                     GLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEH
                     KLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNK
                     TNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFA
                     GRARGRGGGPSQNWNQGYSNYWNQGYGNYGYNSQGYGGYGGYDYTGYNNYYGYGDYSN
                     QQSGYGKVSRRGGHQNSYKPY"
     exon            548..604
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /inference="alignment:Splign:2.1.0"
     exon            605..773
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /inference="alignment:Splign:2.1.0"
     exon            774..935
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /inference="alignment:Splign:2.1.0"
     exon            936..1067
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /inference="alignment:Splign:2.1.0"
     exon            1068..1167
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /inference="alignment:Splign:2.1.0"
     exon            1168..1314
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /inference="alignment:Splign:2.1.0"
     exon            1315..1412
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /inference="alignment:Splign:2.1.0"
     exon            1413..6811
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1723..1728
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /note="hexamer: AATAAA"
     polyA_site      1738
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
     polyA_site      1744
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /note="major polyA site"
     regulatory      2129..2134
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /note="hexamer: AATAAA"
     polyA_site      2150
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
     regulatory      6281..6286
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /note="hexamer: AATAAA"
     polyA_site      6302
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
     regulatory      6788..6793
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
                     /note="hexamer: ATTAAA"
     polyA_site      6811
                     /gene="Hnrnpd"
                     /gene_synonym="Auf1; Hnrpd"
ORIGIN      
        1 ccattttagg tggtccgcgg cggcgccatt aaagcgagga ggaggcgaga gtggccgccg
       61 ctgctacttc attctttttt ttttcagtgc agccggggag agcgagagag cgcgctgcgc
      121 gagagtggga ggcgaggggg gcaggccggg gagaggcgca ggagcccttg cagccacgcg
      181 cgcgccttgt ctagggtgcc tcgcgaggta gagcgggcat cgcgcggcgg cggcggggat
      241 tactttgctg ctagtttcgg ttcgcggcgg cggcggcgtc ggcgggtgtc gtcttcggcg
      301 gcggcagtag cactatgtcg gaggagcagt tcggagggga cggggcggcg gcggcggcaa
      361 cggcggcggt aggcggctcg gcgggcgagc aggagggagc catggtggcg gcggcggcgc
      421 aggggccggc ggcggcggcg ggaagcggga gcggcggcgg cggctctgcg gccggaggca
      481 ccgaaggagg cagcgccgag gcagagggag ccaagatcga cgccagtaag aacgaggagg
      541 atgaaggcca ttcaaactcc tccccacgac acactgaagc agcggcggca cagcgggaag
      601 aatggaaaat gtttatagga ggccttagct gggacaccac aaagaaagat ctgaaggact
      661 acttttccaa atttggtgaa gttgtagact gcactctgaa gttagatcct atcacagggc
      721 gatcaagggg ttttggcttt gtgctattta aagagtcgga gagtgtagat aaggtcatgg
      781 atcagaaaga acataaattg aatgggaaag tcattgatcc taaaagggcc aaagccatga
      841 aaacaaaaga gcctgtcaaa aaaatttttg ttggtggcct ttctccagac acacctgaag
      901 aaaaaataag agagtacttt ggtggttttg gtgaggttga atccatagag ctccctatgg
      961 acaacaagac caataagagg cgtgggttct gttttattac ctttaaggaa gaggagccag
     1021 tgaagaagat aatggaaaag aaataccaca atgttggtct tagtaaatgt gaaataaaag
     1081 tagccatgtc aaaggaacag tatcagcagc agcagcagtg gggatctaga ggagggtttg
     1141 caggcagagc tcgcggaaga ggtggaggcc ccagtcaaaa ctggaaccag ggatatagta
     1201 actattggaa tcaaggctat ggcaactatg gatataacag ccaaggttac ggaggttatg
     1261 gaggatatga ctacactggt tacaacaact actatggata tggtgattat agcaatcagc
     1321 agagtggtta tgggaaagta tccaggcgag gtggacatca aaatagctac aaaccatact
     1381 aaattattcc atttgcaact tatccccaac aggtggtgaa gcagtatttt ccaatttgaa
     1441 gattcatttg aaggtggctc ctgccacctg ctaatagcag ttcaaactaa attttttcta
     1501 tcaagttcct gaatggaagt atgacgttgg gtccctctga agtttaattc tgagttctca
     1561 ttaaaagaat ttgctttcat tgttttattt cttaattgct atgcttcagt atcaatttgt
     1621 gttttatgcc ccccctcccc cccagtattg tagagcaagt cttgtgttaa aaaaagccca
     1681 gtgtgacagt gtcatgatgt agtagtgtct tactggtttt ttaataaatc cttttgtata
     1741 aaaatgtatt ggctctttta tcatcagaat aggaggaagt gaaatactac aaatgtttgt
     1801 cttggattca agtcactaga agcataaatt tgaggggata aaaacaacgg taaactttgt
     1861 ctgaaagagg gcatggttaa aaatgtagtg aattttaaat gtttttagca aaatttgatt
     1921 ttgcccaaga atccctgtct gaattggaaa tgacttaatg tagtcaatgt gcttgttggt
     1981 tgtcttaata ttacttctgt agccattaag ttttatgagt aacttcccaa atacccacgt
     2041 ttttctttat atgtattgtg ctttttaaaa acaaatctgg aaaaatgggc aagaacattt
     2101 gcagacaatt gtttttaagc ttccattaaa taaaaaaaat gtggacttaa ggaaatctat
     2161 taatttaaat agaactgcag ctagtttaga gagtattttt ttcttaaagc tttggtgtaa
     2221 ttagggaaga ttttaaaaaa tgcatagtgt ttatttgtat gtgtgctctt tttttaagtc
     2281 aatttttggg gggttggtct gttaactgag tctaggattt aaaggtaaga tgttcctaga
     2341 aatcttgtca tcccaaaggg gcgggcgcta aggtgaaact tcagggttca gtcagggtca
     2401 ctgctttatg tgtgaaatca ctcaaattgg taagtctctt atgttagcat tcaggacatt
     2461 gatttcaact tggatggaca atttatagtt actactgaat tgtgtgttaa tgtgttcagt
     2521 cctggtaagt tttcagtttg atcagttagt tggaagcaga cttgaagagc tgttagtcac
     2581 gtgagccatg ggtgcagtcg atctgtggtc agatgcctga gtctgtgata gtgaattgtg
     2641 tctaaagaca ttttaatgat aaaagtcagt gctgtaaagt tgaaagttca tgagagacat
     2701 acaatgaggg ctgcagccca tttttaaaaa cattataata caaaagtatg cacatttgtt
     2761 tacatatccc tgcctttgta ttacagtggc aggtttgtgt acttaaactg ggaaagcctc
     2821 agatctatga ttacctggcc tatcatagaa agtgtctaaa taaatcactc tgtcaattga
     2881 atacattagt attagctagc atacttcatt atgcctgttt tccataaata ccacaccaaa
     2941 aacttgcttg gggcagtttg agcctagttc atgagctgct atcagattgg tcttgatcct
     3001 atataatagg ccaaatgtct gtaaacagct gtgctggtgg aatgtagaaa gtcactgcac
     3061 tcagattcaa cttcctgatt ggaagtcatc acagtgtgat taaacatttt cacaaagaat
     3121 agtagataaa taacttggtt tttaatgtta actttgtttc cattaagtca catttaaaaa
     3181 cttatcctca cgcctacctg agttaattat ctgttgacct agatatcttt ctggccactc
     3241 actgacttat ttcttgaact tttgccattt gcataaatct tgtcagcttt gttcttgatt
     3301 atgcattgtc caggctgagc tagttgtctt tccaggaatc cctttgtctc tgaattaggt
     3361 cctttgtttc ctaaatcatc ctgcttgttt ggcacaagtc ttcccaggcc agtgagacct
     3421 ccgtgtcctc tcagcaccat aggggtaggt aaccctggtt aggctggaca ggggtttgct
     3481 gagggagttt gttcatttga atctaggtct tacatgacgt ctttcaaata gggtttttac
     3541 cttgacacta aactgtccag tctaagcagt tctgcaaaat gtgagggaat tatgaacttc
     3601 ttcctgcagt gggtttttat ggttttggtt tgttttttgt tgttttggtt ctttgttgag
     3661 ccctggacaa aaacttccct agttctggtt tctacaattt aaattaaaaa cagaattcat
     3721 cttagaattt ttcaccctct tccccaacta ttctaatcaa tcttaagtat gcccttcatc
     3781 ttttttcctt cctaaggctt ttactgatag tgtaattccg tactcttcaa ccctgggaag
     3841 gctgaagtgg attcttgagc tcatttcaag gctgacctgg gtgttggcaa gaacccagct
     3901 tagaacaaac acatgcaagg ccatcttacc ttacatcctg ttgcttggac ttcttcctgc
     3961 tcaaagtttt tagtggatgc taagtgatct ttgcttccac tgaggagtgg aacactttag
     4021 aatgaacctc tagatagata tttttattgt ctggtgaggg ttactggagt ttcccaccct
     4081 gcctgaaggg tgaatctggc ttacagtgtt ctcatctcaa agggaagaag gcagatggct
     4141 gtgtccagag agagccatca cagtttgctt cagagacact agaatgggct ggaagatcta
     4201 gtggtcttaa tcagacttga aacctggcct ttcttcatta cccatatgtc taccagtact
     4261 tgggctaaca cttaagccat tagggccttt gtaggggtgt tttgagaccc cctccatgct
     4321 aacaaatata caggtttctt aacatttgct cataaacttg taaagcttac tttctcttaa
     4381 tccaccccac atttaacaag ccctggtact tagaatttca gaagagtaat ggcaggtagg
     4441 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgagagagag agagagagag
     4501 agagagagag agagagagag agagagagag agagagaagt ttgtggaaaa tcaggtaatg
     4561 acagctcatc cttttagaat tgtacttcag aatagaaaca tttggtgggc tgttaggtag
     4621 ctttgattac ttgtgggtag acctgctagt attgccagtc ctcaagcaat gagctttctg
     4681 tatcttgttt actagatata tactaccagg tgagtcattt cctggggttc tgttttcttt
     4741 taaaatcttt ccctaaactt aatatgtatt aaaaagtctg gcttttcagt ccattctttg
     4801 tgcactggga tggcaattgc ttcattatat gacaattgct gttcccaagt cagaattcag
     4861 tgtgctgatt tgacatcagt tcgtcccgaa taagttcctg ttaccaggat ttacattcag
     4921 cacattagaa acttgttggt gtgcttttat tcttggagca ttttccttag actaccttcc
     4981 actttgagtg ctctgtttag gatgttgagg tgttaggatt cttgacagcc agaaagactg
     5041 aacccactat ctgggcacag tgttcgtgtt gctctataaa tgtatgcttt ttttgatttg
     5101 gggttgtttt acctacattg tcaaactaga tccatgctta acagtgataa tgaaggcttt
     5161 ttgtttgttt tgtttgtggg tcctcccccc ccccccaaga cagggtttct ctgtaggctg
     5221 tcctagaact tgttcttttt taaccaaaat ttggcaaggc tgaaaatgga atcctataat
     5281 caatgctggc cacattaaag ttaatagttg agaagtcttg tctgaatttc cttgggcaaa
     5341 aagattctag ccagttcaat accctgttgt gcaaattcaa tttgctgtta taatttgctc
     5401 tcagttatca gttggaagga ggttaattct aatgtacttg gaagaggcct gtagaccatc
     5461 tataactgca tcagttgtac agcgttgttg cctgggattc tctagttcac ataaactccc
     5521 aagtcttagc cgtggtgatg gctacagtgt ggaagatggt gagcattcta gtgagtatcg
     5581 cgatgacggc agtaaagagc agcaggcagc cgtggctggg ctcactgacc gtggctgtaa
     5641 gttacggagg cagcacacac ttctgtacac acctctcatc agttaccgga gtcattgcat
     5701 tgcggactaa ctggctgact caagttgtct tgctactgaa gtcttgagtt ggtctcatgc
     5761 atttaccctg ttgacttgag caccttaaag tcgaaaggat gtctggttgt ggctttattg
     5821 taaacagcct taggtaaaga ggggagtata tcggttagga aggtgaaaaa tgatacttcc
     5881 aagttcagtg ggaaaccctg ggtttatccc ccagcttaag aaagaatgcc taacaatgtt
     5941 tcagaattag attctgtgga aggtgagggt gttagaacag tccaaatttg ttattgtaga
     6001 cttgcagtgg gaggaatttt taaatataca gatcagtcga cactcattaa cttcactgat
     6061 aaaggtggaa acggatgtgg caacacttct aagttcattt gtatatgttt gtaatttgat
     6121 tggttgtatt ctgttgcact ctagaatttg aaggcaaggt tacctctgct ttttaatttt
     6181 ttttttttta aagaaagaaa aaacactgaa agaaacttca aaagatctgt taatgctaat
     6241 acctgaatgt ggcatttaac atgtcatgga aactgctttg aataaatact tgagaaaagg
     6301 aatgaaataa ttgccgtttt tgttgttgag tgaatgggtg tggtttaatg agcgtaatca
     6361 tttttataaa acagctgtga gactgaagtg gaatccttat taaatgtgga aaatggcctt
     6421 tgaggattac agtagagatt caactaagag agtaaataaa gcttgaaact aattcgttgt
     6481 aaattgcttc tacaatcatt gctctatata gcatgctatt gccaatcagt tttatgtatt
     6541 aagacctatc agcatgtctt ttttaggttg acctcatttt aaattataag atgctctctg
     6601 taccgtttta acatttccag gatttattct ttctaggcaa attccactgg actgtttcca
     6661 ttgtagaagc ttccttatag attcttcaaa tgaagcttac agtgtgcttt cttggggttt
     6721 tgatttgcac taaattttat tttctgaaag atcacttatg tttataatgt agtgctttgt
     6781 cttaacaatt aaactttcca gcactcatgc a
//
