LOCUS       NM_178277               5211 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus HMG box domain containing 3 (Hmgxb3), transcript
            variant 1, mRNA.
ACCESSION   NM_178277
VERSION     NM_178277.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 5211)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 5211)
  AUTHORS   Butterfield,N.C., Curry,K.F., Steinberg,J., Dewhurst,H.,
            Komla-Ebri,D., Mannan,N.S., Adoum,A.T., Leitch,V.D., Logan,J.G.,
            Waung,J.A., Ghirardello,E., Southam,L., Youlten,S.E.,
            Wilkinson,J.M., McAninch,E.A., Vancollie,V.E., Kussy,F.,
            White,J.K., Lelliott,C.J., Adams,D.J., Jacques,R., Bianco,A.C.,
            Boyde,A., Zeggini,E., Croucher,P.I., Williams,G.R. and
            Bassett,J.H.D.
  TITLE     Accelerating functional gene discovery in osteoarthritis
  JOURNAL   Nat Commun 12 (1), 467 (2021)
   PUBMED   33473114
  REMARK    Erratum:[Nat Commun. 2021 May 28;12(1):3302. PMID: 34050183]
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 5211)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 5211)
  AUTHORS   Perez-Garcia,V., Fineberg,E., Wilson,R., Murray,A., Mazzeo,C.I.,
            Tudor,C., Sienerth,A., White,J.K., Tuck,E., Ryder,E.J., Gleeson,D.,
            Siragher,E., Wardle-Jones,H., Staudt,N., Wali,N., Collins,J.,
            Geyer,S., Busch-Nentwich,E.M., Galli,A., Smith,J.C., Robertson,E.,
            Adams,D.J., Weninger,W.J., Mohun,T. and Hemberger,M.
  TITLE     Placentation defects are highly prevalent in embryonic lethal mouse
            mutants
  JOURNAL   Nature 555 (7697), 463-468 (2018)
   PUBMED   29539633
REFERENCE   5  (bases 1 to 5211)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   6  (bases 1 to 5211)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 5211)
  AUTHORS   Guo,G., Huss,M., Tong,G.Q., Wang,C., Li Sun,L., Clarke,N.D. and
            Robson,P.
  TITLE     Resolution of cell fate decisions revealed by single-cell gene
            expression analysis from zygote to blastocyst
  JOURNAL   Dev Cell 18 (4), 675-685 (2010)
   PUBMED   20412781
REFERENCE   8  (bases 1 to 5211)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   9  (bases 1 to 5211)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   10 (bases 1 to 5211)
  AUTHORS   Piao,Y., Ko,N.T., Lim,M.K. and Ko,M.S.
  TITLE     Construction of long-transcript enriched cDNA libraries from
            submicrogram amounts of total RNAs by a universal PCR amplification
            method
  JOURNAL   Genome Res 11 (9), 1553-1558 (2001)
   PUBMED   11544199
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AB045322.1, BC058089.1 and BC025148.1.
            
            Transcript Variant: This variant (1) represents the longer
            transcript. It encodes the longer protein (isoform 1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC079580.1, SRR1660815.269788.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-702               AB045322.1         2-703
            703-3879            BC058089.1         1-3177
            3880-5211           BC025148.1         748-2079
FEATURES             Location/Qualifiers
     source          1..5211
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 34.41 cM"
     gene            1..5211
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /note="HMG box domain containing 3"
                     /db_xref="GeneID:106894"
                     /db_xref="MGI:MGI:2441817"
     exon            1..472
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            473..608
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     CDS             475..4335
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /note="isoform 1 is encoded by transcript variant 1"
                     /codon_start=1
                     /product="HMG domain-containing protein 3 isoform 1"
                     /protein_id="NP_840061.1"
                     /db_xref="CCDS:CCDS89249.1"
                     /db_xref="GeneID:106894"
                     /db_xref="MGI:MGI:2441817"
                     /translation="MDAPYDGAEVTVLMEEIEEAYYTSPGPPKKKKKYKIHGEKAKKP
                     RSAYLLYYYDIYLKVQQELPHLPQSEINKKISESWRLLSVAERSYYLEKAKLEKEGLD
                     PNSKLSALTAVVPDIPGFRKILPRSEYIIIPKSTLQEDRSCPQLELCVAQNQMSPKGS
                     TLMSNASPDVVASHAGMAEQCLAVEALAEEVGALPQPGTVQEIATSEILSHDMLLEEA
                     SLEVGESHQPYQTSLVIEETLVNGSSDLPTGSLAVPHSQVGESLSVVTVMRDSSESSP
                     SAPATQFIMLPLPAYSVVENPSSIKLTTTYTRRGHGTCTSPGCSFTYVTRHKPPKCPT
                     CGNFLGGKWIPKEKPAKVKVELASGVSSKGSVIKRNQQSVTTEQNPSKENASKLTLEN
                     SEAVSQLLNVAPPGEGGEDREWEEVIVSDAHVLVKEVPGNRGTAVTKMPVVKSGAQAE
                     ISLGTTENDSPGPDILPSAEGTSSSSLLQAHKKSPGVDLFTTGPKAPELKGRARGKPS
                     LLAAARPMRAILPAPTSVGRGSGVGLPRARQAFPLDKTPSVRTCGLKPSTLKQLGQPI
                     QQPPSTGEVKLSNCASSRTPQLKIVEVKPDLFPPYKYSCTVTLDLGLATSRGRGKCKN
                     PSCSYVYTNRHKPRICPSCGFNLAKDRTEKTPKAIEASSPHPDVPSTTEALNPTQREV
                     QRQSTLQLLRKVLQIPENESELAEVFALIHELNSSRLILSNVSEETVTIEQTSWSNYY
                     ESPSTQCLLCSSPLFKGGHNSLAGPQECWLLTANRLQVVTAQVKMCLNPHCLALHSFT
                     DIYTGLFNVGNKLLVSLDLLFAIRNQIKLGEDPRVSVGVVLKSVQEQTEKTLTSEELS
                     QLQELLCNGYWAFECLTVRDYNDMICGICGVAPKVEMAQRNEENVLALKSVEFTWPEF
                     LGSSEVNVEDFWTTMETEVIEQVAFPASIPITKFDASVIAPFFPPLMRGAVVVNTEKD
                     KTQDMQPVPGNGSALVRLLQEGTCKLEELGSYSGEELQYLLEQCDIPFSPEDSRDQLC
                     FSLLALYESVQNGARARPPPAHFTGGKIYKVCPHQVVCGSKYLVRGESARDHVDLLAS
                     SRHWPPVYVVDMATPVALCADLCYPELTSQMWGKNQGCFSNPTEPVVSVSCPELLDQH
                     YSVDVTEAENSVQHPVTKSATRRIVHANTKPDPSDPSAGHRSLSLCPELAPYASTTDS
                     KLSSVRQRPIAFDNATHYYLYNRLMDFLTSREIVNRQIHDIVQSCQPGEVVIRDTLYR
                     LGVAQIKTEAQEEGEEEEVASVVE"
     exon            609..783
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            784..1281
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            1282..1380
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..1512
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            1513..1931
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            1932..2104
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            2105..2202
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            2203..2301
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            2302..2451
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            2452..2753
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            2754..2881
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            2882..3013
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            3014..3198
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            3199..3418
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            3419..3552
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            3553..3669
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            3670..3879
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     exon            3880..5198
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /inference="alignment:Splign:2.1.0"
     regulatory      5165..5170
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /note="hexamer: AATAAA"
     regulatory      5175..5180
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /note="hexamer: ATTAAA"
     polyA_site      5183
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /note="major polyA site"
     polyA_site      5198
                     /gene="Hmgxb3"
                     /gene_synonym="2510002C16Rik; A630042L21Rik; mKIAA0194"
                     /note="major polyA site"
ORIGIN      
        1 gtgcgccgcg agggccgccg ggacgggtct ccctggcgat cagtggtgtg ctgtcgcctc
       61 tgccaccagc gcgccggtgc cacggagact cgtgtccttg ctaccttctt cgggcttccc
      121 ggggcctgat ccccggggcc ctcggcaggc gtcagccgag cctgtgcgcg aacctgcggc
      181 cctccgctcg cccttcacga cccggcagcg cgactcggac tcagggagcg aaagggactg
      241 tggcgactcc gcgccgtgtg tcgccgggcg gggccgcggg gccggggctc ctccagcccc
      301 cgggatgcgt gcgcgagctc tcgcctccac tttctcttta ccgctgtcac gcgtggagcc
      361 gcctctcgcc tacagcgggg agcgcgagtg cacagatcag cagcacccct gtcgagcccc
      421 ggtgccgggt acccccggga atgtgagccg cgaggctcgc aagctcctcc ggccatggat
      481 gccccgtatg atggtgctga ggtaactgtc ctgatggagg aaatcgagga agcttattac
      541 acttcccctg ggccgcctaa gaagaagaag aagtataaaa tacatggaga gaaggccaag
      601 aaacccaggt ctgcctacct actgtactac tacgacatct acttgaaagt gcagcaagag
      661 ctcccccacc tgccccagtc cgagatcaat aagaagatta gtgagagctg gaggctcctc
      721 agcgtggccg agagaagtta ctacttggag aaagccaagc tagagaagga agggttggat
      781 cctaactcta agctctctgc actgactgct gtggttccgg acatcccagg tttccgaaag
      841 atccttcccc gatcggaata catcatcatt cccaagagca ccctgcagga agacaggagc
      901 tgcccgcagc tagagctctg tgtggctcag aaccagatgt cccctaaagg atctactctc
      961 atgtctaatg cttccccaga tgtagtagcc agccatgccg gcatggcaga gcagtgcctg
     1021 gctgtggagg ccctggctga ggaagtggga gcccttcccc agccaggtac tgtgcaagag
     1081 attgccacct cagagatcct cagccacgat atgctcttgg aggaggcgtc cttggaggta
     1141 ggagagagcc accaacctta ccagacaagc ctggtaattg aagagacttt agtaaatggc
     1201 tcatcagacc tccccactgg aagcctggcc gtgccacatt cccaggttgg ggagagcttg
     1261 tcagtggtaa cagtcatgag ggactccagt gagagtagcc cgtctgctcc agccactcag
     1321 ttcatcatgc tgcctctgcc tgcttactcg gtcgtggaga acccttcttc catcaagctg
     1381 actacaacat acacccgtcg gggccacggg acatgcacaa gtccaggttg ttcttttacc
     1441 tatgtcacca ggcacaaacc acctaagtgc cctacttgtg gtaacttcct aggagggaag
     1501 tggatcccaa aggaaaagcc agccaaagtc aaagtggaat tggcttcggg tgtctcctcc
     1561 aaaggttctg tgattaaaag aaatcagcag tctgtcacca ctgagcaaaa cccctctaag
     1621 gaaaatgctt caaaactgac tctggagaac tcagaagctg taagccagct cttaaacgtg
     1681 gctcctccag gagaaggggg tgaggacaga gagtgggagg aagtgattgt ctccgatgct
     1741 catgttttgg tcaaggaagt tcctgggaat cgtggtacag cggtaactaa gatgcctgtt
     1801 gtcaagagtg gtgcccaggc tgagatctct ctggggacaa ctgagaatga cagtcctgga
     1861 ccggacatac tgccatcggc tgaggggacc agctcctcca gtttactcca agctcacaaa
     1921 aagtctccag gagttgacct gttcaccact ggacccaaag ccccagagct gaaaggcaga
     1981 gcacgaggca agccctcctt gctggctgca gcgagaccta tgagagcaat cctaccagcc
     2041 ccaacaagtg ttgggcgggg cagcggcgtg ggactgccca gggccaggca ggctttcccc
     2101 ctggataaga ctccctcggt gaggacttgt ggcctaaagc caagcacgct gaaacagctg
     2161 ggccaaccca tccagcagcc acctagcact ggtgaagtaa agctatccaa ctgcgcaagc
     2221 agcaggaccc cacagttgaa aatcgtagag gtcaagcctg acctgttccc tccgtataag
     2281 tatagctgca ctgtcacgct ggatttgggc ctggctacat cgagaggacg gggaaagtgc
     2341 aaaaatccct cctgtagcta tgtctacacc aaccgacaca aacctcggat ttgtcccagc
     2401 tgtggtttca accttgccaa agacaggact gagaaaactc caaaggccat tgaggcgagc
     2461 tcaccacacc ccgatgtgcc aagtaccaca gaagccctga acccaaccca gagggaggtc
     2521 cagcgtcagt ccacactgca gctgctgcgg aaagtcctgc agattcctga gaacgagtca
     2581 gagctggctg aggtctttgc cttgattcat gaactaaata gctctcgact tatcctgtcc
     2641 aacgtgagtg aggagacagt caccatcgag cagacctctt ggtcgaatta ttatgagtct
     2701 ccatccacgc agtgccttct ctgtagcagc ccattgttca aagggggaca caactctctg
     2761 gccgggcccc aagaatgctg gctcctgaca gctaaccggc tacaggtggt gactgcccag
     2821 gtgaagatgt gtctgaaccc tcattgtttg gccttgcaca gcttcacgga catctacaca
     2881 ggtctcttta atgtggggaa caagttgcta gtcagcctgg acttactttt cgcaatccgg
     2941 aaccagatta agctgggaga ggaccccaga gtgtctgtcg gtgttgtgct gaagtctgtg
     3001 caggaacaaa cagagaagac cctgacctca gaggagctga gccagctgca ggagctgttg
     3061 tgcaatggct attgggcttt tgagtgtctc actgttcgcg actacaatga catgatctgt
     3121 ggcatctgtg gtgtggcccc caaagtggaa atggctcaga ggaatgaaga gaatgtgctg
     3181 gccctgaaga gtgtggagtt tacctggcct gaattcttgg gctccagtga ggtgaacgta
     3241 gaggactttt ggaccacaat ggagacggaa gtgattgagc aggttgcgtt ccctgcgagc
     3301 atccccatca ccaagttcga tgcctctgtt attgctccct tcttcccacc actcatgcga
     3361 ggagctgtgg ttgtcaacac tgagaaagac aaaacccagg acatgcagcc agtacctggc
     3421 aacggcagtg ccttggtgag actgctgcag gaaggcacct gcaagcttga ggagcttggc
     3481 tcctacagtg gggaggaact acagtacctt ctggagcagt gcgacatccc ctttagccca
     3541 gaagactcga gggatcagct ctgcttctcc ttgttggccc tctatgaatc tgtacagaat
     3601 ggagccagag ccagacctcc cccagctcat ttcaccgggg gtaaaatcta caaagtgtgc
     3661 ccccatcagg tggtctgtgg ttccaagtat cttgttcgag gtgaaagtgc ccgtgatcac
     3721 gtggatctgc ttgcctcttc ccgccactgg ccacctgtct atgtggtaga tatggccaca
     3781 ccagtggccc tatgtgctga cctctgctac ccagagctca ctagccagat gtgggggaag
     3841 aaccagggct gtttctctaa ccctacagag ccagttgtga gtgtgtcctg ccctgaactc
     3901 ttggaccagc attattctgt ggatgtgaca gaggctgaaa actcagtgca gcatccagtc
     3961 accaagagtg cgacacggcg tattgtccat gcaaacacaa agcccgatcc cagtgacccc
     4021 agtgctggcc accgttcctt atcactgtgc ccagagctgg caccttatgc ctctaccacg
     4081 gacagcaagc tcagcagtgt ccgccagagg cccatcgcct ttgacaatgc cacccactat
     4141 tacctctaca accgcctcat ggacttcctc accagccgag agattgtcaa caggcagatc
     4201 catgacattg tgcagagctg ccagcctggc gaggtggtca ttcgcgacac cctctatcgc
     4261 cttggggttg cccagatcaa gacggaggcc caggaggaag gagaggaaga ggaagtagcc
     4321 tcagtggtgg aataagccag gtttttatgt acagggcctg catcatctct ctcaagccat
     4381 aatctggccc ttgcccaggg cagtcctatt gagggacctg cagtcctctt tagggagggc
     4441 ctctgactgc tggaactgac caaagagctt ccatttcatg agcacagtgg ggcctcgacc
     4501 tctggggctc aggagaggcg ctgggaagcc tctccttgac ctgagagagc acgtggaggc
     4561 aggacatgat gttcttaagg atctggtgct gataggaagg ccggggcctg gttgcccaga
     4621 cccacaacca cccgggttcc tgcaccaggt ggagccgcca ttgagctaag ctgtcccgcg
     4681 gggaggagct ctggctcctg tcttgtgggc ttcctagcct gccttgctgg cttatttact
     4741 cttggaatcc cttggggccc ttcattctcc ctaaaggagg ggtgcattct ctgttcctcc
     4801 aactctccct gttcccacac cttggggcag ttgaggagaa ggaacagctc ctccaggact
     4861 ctctcagccc cgggtttggg ggaagagaat ccttcctcct ttctctggcc actgctacta
     4921 taccctacgt cctctgggtc ctcagaccct caccacagag gggatgtggc ccgtggttgt
     4981 gacatagctg acaagcagta ggaaaactcc cttctgtgaa ggggaagcag atagggccat
     5041 aagcaaacag cagcatgggc tcaggtgccc gcggtttgct tagggcccag gattggccaa
     5101 gtgctattta atttattgag agggtgggat aggtggcttt ccctctcgtt cttcccccaa
     5161 caagaataaa gtttattaaa ttatctggtt ttgatgaaaa aaaaaaaaaa a
//
