LOCUS       NM_026122                923 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus high mobility group nucleosomal binding domain 3
            (Hmgn3), transcript variant a, mRNA.
ACCESSION   NM_026122
VERSION     NM_026122.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 923)
  AUTHORS   Zhang,W., Yao,C., Luo,Y., Li,Q., Zhao,Q., Zhao,Y., Wang,Y.,
            Geng,M., Wang,Q., Xu,M., Sun,S., Wu,D., Gao,Q., Wu,X. and Shuai,L.
  TITLE     Rif1 and Hmgn3 regulate the conversion of murine trophoblast stem
            cells
  JOURNAL   Cell Rep 38 (13), 110570 (2022)
   PUBMED   35354046
  REMARK    GeneRIF: Rif1 and Hmgn3 regulate the conversion of murine
            trophoblast stem cells.
REFERENCE   2  (bases 1 to 923)
  AUTHORS   Li,D.D., Guo,C.H., Yue,L., Duan,C.C., Yang,Z.Q., Cao,H., Guo,B. and
            Yue,Z.P.
  TITLE     Expression, regulation and function of Hmgn3 during decidualization
            in mice
  JOURNAL   Mol Cell Endocrinol 413, 13-25 (2015)
   PUBMED   26112184
  REMARK    GeneRIF: Hmgn3 may play an important role during mouse
            decidualization.
REFERENCE   3  (bases 1 to 923)
  AUTHORS   Osipovich,A.B., Long,Q., Manduchi,E., Gangula,R., Hipkens,S.B.,
            Schneider,J., Okubo,T., Stoeckert,C.J. Jr., Takada,S. and
            Magnuson,M.A.
  TITLE     Insm1 promotes endocrine cell differentiation by modulating the
            expression of a network of genes that includes Neurog3 and Ripply3
  JOURNAL   Development 141 (15), 2939-2949 (2014)
   PUBMED   25053427
REFERENCE   4  (bases 1 to 923)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   5  (bases 1 to 923)
  AUTHORS   Kugler,J.E., Horsch,M., Huang,D., Furusawa,T., Rochman,M.,
            Garrett,L., Becker,L., Bohla,A., Holter,S.M., Prehn,C.,
            Rathkolb,B., Racz,I., Aguilar-Pimentel,J.A., Adler,T., Adamski,J.,
            Beckers,J., Busch,D.H., Eickelberg,O., Klopstock,T., Ollert,M.,
            Stoger,T., Wolf,E., Wurst,W., Yildirim,A.O., Zimmer,A.,
            Gailus-Durner,V., Fuchs,H., Hrabe de Angelis,M., Garfinkel,B.,
            Orly,J., Ovcharenko,I. and Bustin,M.
  TITLE     High mobility group N proteins modulate the fidelity of the
            cellular transcriptional profile in a tissue- and variant-specific
            manner
  JOURNAL   J Biol Chem 288 (23), 16690-16703 (2013)
   PUBMED   23620591
  REMARK    GeneRIF: Phenotypic analysis of Hmgn1(tm1/tm1), Hmgn3(tm1/tm1), and
            Hmgn5(tm1/tm1) mice and their wild type littermates with a battery
            of standardized tests uncovered variant-specific abnormalities.
REFERENCE   6  (bases 1 to 923)
  AUTHORS   Tamplin,O.J., Kinzel,D., Cox,B.J., Bell,C.E., Rossant,J. and
            Lickert,H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   7  (bases 1 to 923)
  AUTHORS   Lucey,M.M., Wang,Y., Bustin,M. and Duncan,M.K.
  TITLE     Differential expression of the HMGN family of chromatin proteins
            during ocular development
  JOURNAL   Gene Expr Patterns 8 (6), 433-437 (2008)
   PUBMED   18502697
REFERENCE   8  (bases 1 to 923)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
REFERENCE   9  (bases 1 to 923)
  AUTHORS   West,K.L., Castellini,M.A., Duncan,M.K. and Bustin,M.
  TITLE     Chromosomal proteins HMGN3a and HMGN3b regulate the expression of
            glycine transporter 1
  JOURNAL   Mol Cell Biol 24 (9), 3747-3756 (2004)
   PUBMED   15082770
  REMARK    GeneRIF: results suggest that HMGN3 regulates glycine transporter 1
            expression and demonstrate that members of the HMGN family can
            regulate the transcription of specific genes
REFERENCE   10 (bases 1 to 923)
  AUTHORS   West,K.L., Ito,Y., Birger,Y., Postnikov,Y., Shirakawa,H. and
            Bustin,M.
  TITLE     HMGN3a and HMGN3b, two protein isoforms with a tissue-specific
            expression pattern, expand the cellular repertoire of
            nucleosome-binding proteins
  JOURNAL   J Biol Chem 276 (28), 25959-25969 (2001)
   PUBMED   11356838
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CJ150650.1, AK153223.1 and CD742335.1.
            
            On May 21, 2009 this sequence version replaced NM_026122.3.
            
            Transcript Variant: This variant (a) encodes the longer isoform
            (Hmgn3a).
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BK000004.1, DV064619.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-108               CJ150650.1         2-109
            109-667             AK153223.1         69-627
            668-923             CD742335.1         1-256               c
FEATURES             Location/Qualifiers
     source          1..923
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="9"
                     /map="9 45.29 cM"
     gene            1..923
                     /gene="Hmgn3"
                     /gene_synonym="1110002A15Rik; 6330514M13Rik; TRIP7"
                     /note="high mobility group nucleosomal binding domain 3"
                     /db_xref="GeneID:94353"
                     /db_xref="MGI:MGI:2138069"
     exon            1..177
                     /gene="Hmgn3"
                     /gene_synonym="1110002A15Rik; 6330514M13Rik; TRIP7"
                     /inference="alignment:Splign:2.1.0"
     CDS             163..462
                     /gene="Hmgn3"
                     /gene_synonym="1110002A15Rik; 6330514M13Rik; TRIP7"
                     /note="isoform Hmgn3a is encoded by transcript variant a;
                     high mobility group nucleosome-binding domain-containing
                     protein 3"
                     /codon_start=1
                     /product="high mobility group nucleosome-binding
                     domain-containing protein 3 isoform Hmgn3a"
                     /protein_id="NP_080398.1"
                     /db_xref="CCDS:CCDS52872.1"
                     /db_xref="GeneID:94353"
                     /db_xref="MGI:MGI:2138069"
                     /translation="MPKRKSPENTEGKDGTKLTKQEPTRRSARLSAKPVPPKPESKPR
                     KTSAKKEPGTKISRGAKGKKEEKQEAGEEGTAPSANGDTKVEEAQRTESIEKEGE"
     exon            178..228
                     /gene="Hmgn3"
                     /gene_synonym="1110002A15Rik; 6330514M13Rik; TRIP7"
                     /inference="alignment:Splign:2.1.0"
     exon            229..258
                     /gene="Hmgn3"
                     /gene_synonym="1110002A15Rik; 6330514M13Rik; TRIP7"
                     /inference="alignment:Splign:2.1.0"
     exon            259..309
                     /gene="Hmgn3"
                     /gene_synonym="1110002A15Rik; 6330514M13Rik; TRIP7"
                     /inference="alignment:Splign:2.1.0"
     exon            310..423
                     /gene="Hmgn3"
                     /gene_synonym="1110002A15Rik; 6330514M13Rik; TRIP7"
                     /inference="alignment:Splign:2.1.0"
     exon            424..911
                     /gene="Hmgn3"
                     /gene_synonym="1110002A15Rik; 6330514M13Rik; TRIP7"
                     /inference="alignment:Splign:2.1.0"
     regulatory      883..888
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hmgn3"
                     /gene_synonym="1110002A15Rik; 6330514M13Rik; TRIP7"
                     /note="hexamer: AATAAA"
     polyA_site      911
                     /gene="Hmgn3"
                     /gene_synonym="1110002A15Rik; 6330514M13Rik; TRIP7"
                     /note="major polyA site"
ORIGIN      
        1 gagcgagtgg agcgccgggg gaggaagcgg aggtgcaggt cggagaggcc gggctagccg
       61 agcccattgc gggagtagca gcagcggcca ggcagcatcc agcagtgtgc caggcggccc
      121 agaacattgc tttacttttt ttgctgcacc aacgtagtca ttatgccgaa gagaaagtct
      181 cccgagaaca cagagggcaa agatggaacc aagctaacta agcaggagcc cacaagacgg
      241 tcggccaggt tgtccgcgaa acctgttcca ccaaaaccgg agtctaaacc aagaaaaaca
      301 tcagctaaga aagaacctgg aacaaagatt agcagaggtg ctaaggggaa gaaggaagaa
      361 aagcaggaag ctggagagga aggtactgca ccatctgcaa atggtgacac taaagttgaa
      421 gaggcacaga gaactgaatc tatagaaaag gagggagagt gaattgtcgt ggaaaactag
      481 ggtcgatttc acgtacctct cgggacaact tttaaaagct atttttacca agtattttgt
      541 aaatgctaat tttttaggac tctattagtc agcataaaat ctatatgaag aagatggaca
      601 ttttatcctc ttatggtgat gttttttgga aatttccatc atcctcaagt cacgcaaata
      661 ccaatttcac atcggagctg cgtgtgaaat ggattcagca ttccgcgccc ttgctttaca
      721 attttagtcc tgtgcagact gtggtgtttt tactgagcgt atttgaattt tttcatgcaa
      781 tttttctaga gcaataatca gtggtgcttt tgtgcctagg ttttatgtga ttttaatgaa
      841 atatggatag ttgtggccac ctgctgacta tttgtggttt aaaataaaaa ggttttcttg
      901 tctgcaaaat aaaaaaaaaa aaa
//
