LOCUS       NM_001370902           15654 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus hemicentin 2 (Hmcn2), mRNA.
ACCESSION   NM_001370902 XM_006498502
VERSION     NM_001370902.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 15654)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 15654)
  AUTHORS   Zhang,J.L., Richetti,S., Ramezani,T., Welcker,D., Lutke,S.,
            Pogoda,H.M., Hatzold,J., Zaucke,F., Keene,D.R., Bloch,W., Sengle,G.
            and Hammerschmidt,M.
  TITLE     Vertebrate extracellular matrix protein hemicentin-1 interacts
            physically and genetically with basement membrane protein nidogen-2
  JOURNAL   Matrix Biol 112, 132-154 (2022)
   PUBMED   36007682
REFERENCE   3  (bases 1 to 15654)
  AUTHORS   Welcker,D., Stein,C., Feitosa,N.M., Armistead,J., Zhang,J.L.,
            Lutke,S., Kleinridders,A., Bruning,J.C., Eming,S.A., Sengle,G.,
            Niehoff,A., Bloch,W. and Hammerschmidt,M.
  TITLE     Hemicentin-1 is an essential extracellular matrix component of the
            dermal-epidermal and myotendinous junctions
  JOURNAL   Sci Rep 11 (1), 17926 (2021)
   PUBMED   34504132
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 15654)
  AUTHORS   Lin,M.H., Pope,B.D. 3rd, Sasaki,T., Keeley,D.P., Sherwood,D.R. and
            Miner,J.H.
  TITLE     Mammalian hemicentin 1 is assembled into tracks in the
            extracellular matrix of multiple tissues
  JOURNAL   Dev Dyn 249 (6), 775-788 (2020)
   PUBMED   32035013
REFERENCE   5  (bases 1 to 15654)
  AUTHORS   Naba,A., Clauser,K.R., Mani,D.R., Carr,S.A. and Hynes,R.O.
  TITLE     Quantitative proteomic profiling of the extracellular matrix of
            pancreatic islets during the angiogenic switch and insulinoma
            progression
  JOURNAL   Sci Rep 7, 40495 (2017)
   PUBMED   28071719
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 15654)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
REFERENCE   7  (bases 1 to 15654)
  AUTHORS   Naba,A., Clauser,K.R., Hoersch,S., Liu,H., Carr,S.A. and Hynes,R.O.
  TITLE     The matrisome: in silico definition and in vivo characterization by
            proteomics of normal and tumor extracellular matrices
  JOURNAL   Mol Cell Proteomics 11 (4), M111.014647 (2012)
   PUBMED   22159717
REFERENCE   8  (bases 1 to 15654)
  AUTHORS   Xu,X. and Vogel,B.E.
  TITLE     A secreted protein promotes cleavage furrow maturation during
            cytokinesis
  JOURNAL   Curr Biol 21 (2), 114-119 (2011)
   PUBMED   21215633
REFERENCE   9  (bases 1 to 15654)
  AUTHORS   Xu,X., Dong,C. and Vogel,B.E.
  TITLE     Hemicentins assemble on diverse epithelia in the mouse
  JOURNAL   J Histochem Cytochem 55 (2), 119-126 (2007)
   PUBMED   17015624
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL732572.10, AL928861.5 and AL732564.12.
            
            On Jun 11, 2019 this sequence version replaced XM_006498502.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were inferred from orthologous alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-345               AL732572.10        171436-171780
            346-416             AL732572.10        190959-191029
            417-575             AL732572.10        192518-192676
            576-698             AL732572.10        193611-193733
            699-870             AL732572.10        200160-200331
            871-977             AL732572.10        201116-201222
            978-1098            AL732572.10        201573-201693
            1099-1362           AL732572.10        203566-203829
            1363-1507           AL732572.10        207082-207226
            1508-1629           AL732572.10        207623-207744
            1630-1902           AL732572.10        209713-209985
            1903-2044           AL732572.10        210820-210961
            2045-2172           AL732572.10        211270-211397
            2173-2286           AL732572.10        211726-211839
            2287-2436           AL732572.10        213328-213477
            2437-2625           AL928861.5         6281-6469
            2626-2721           AL928861.5         7197-7292
            2722-2849           AL928861.5         7558-7685
            2850-2994           AL928861.5         9617-9761
            2995-3107           AL928861.5         14351-14463
            3108-3264           AL928861.5         14574-14730
            3265-3430           AL928861.5         16181-16346
            3431-3558           AL928861.5         23641-23768
            3559-3813           AL928861.5         25628-25882
            3814-3900           AL928861.5         26442-26528
            3901-4095           AL928861.5         27727-27921
            4096-4226           AL928861.5         29050-29180
            4227-4374           AL928861.5         29440-29587
            4375-4501           AL928861.5         30239-30365
            4502-4656           AL928861.5         30550-30704
            4657-4935           AL928861.5         32011-32289
            4936-5214           AL928861.5         33567-33845
            5215-5323           AL928861.5         34403-34511
            5324-5493           AL928861.5         34655-34824
            5494-5648           AL928861.5         36340-36494
            5649-5745           AL928861.5         36830-36926
            5746-5841           AL928861.5         37530-37625
            5842-6018           AL928861.5         38362-38538
            6019-6176           AL928861.5         40089-40246
            6177-6300           AL928861.5         41421-41544
            6301-6476           AL928861.5         42044-42219
            6477-6573           AL928861.5         42876-42972
            6574-6693           AL928861.5         43089-43208
            6694-6855           AL928861.5         44281-44442
            6856-7137           AL928861.5         45419-45700
            7138-7305           AL928861.5         47000-47167
            7306-7419           AL928861.5         47812-47925
            7420-7506           AL928861.5         49053-49139
            7507-7698           AL928861.5         50114-50305
            7699-7872           AL928861.5         50886-51059
            7873-7986           AL928861.5         51181-51294
            7987-8129           AL928861.5         51781-51923
            8130-8280           AL928861.5         52392-52542
            8281-8499           AL928861.5         54331-54549
            8500-8613           AL928861.5         56649-56762
            8614-8801           AL928861.5         57121-57308
            8802-8898           AL928861.5         57874-57970
            8899-9060           AL928861.5         58654-58815
            9061-9174           AL928861.5         58967-59080
            9175-9377           AL928861.5         59927-60129
            9378-9459           AL928861.5         60601-60682
            9460-9591           AL928861.5         62110-62241
            9592-9735           AL928861.5         65222-65365
            9736-9895           AL928861.5         65458-65617
            9896-10020          AL928861.5         65698-65822
            10021-10204         AL928861.5         66173-66356
            10205-10302         AL928861.5         68003-68100
            10303-10569         AL928861.5         68490-68756
            10570-10760         AL928861.5         69292-69482
            10761-10842         AL928861.5         69597-69678
            10843-10979         AL928861.5         69766-69902
            10980-11121         AL928861.5         70538-70679
            11122-11266         AL928861.5         70754-70898
            11267-11394         AL928861.5         71545-71672
            11395-11551         AL928861.5         72197-72353
            11552-11673         AL928861.5         73588-73709
            11674-11838         AL928861.5         74355-74519
            11839-11946         AL928861.5         75739-75846
            11947-12081         AL928861.5         76115-76249
            12082-12216         AL928861.5         76482-76616
            12217-12407         AL928861.5         77533-77723
            12408-12621         AL928861.5         78675-78888
            12622-12756         AL928861.5         80084-80218
            12757-12947         AL928861.5         81111-81301
            12948-13029         AL928861.5         83648-83729
            13030-13299         AL928861.5         90474-90743
            13300-13449         AL928861.5         96208-96357
            13450-13587         AL928861.5         98210-98347
            13588-13709         AL928861.5         98443-98564
            13710-13743         AL928861.5         98783-98816
            13744-13947         AL732564.12        2001-2204
            13948-14010         AL732564.12        3212-3274
            14011-14133         AL732564.12        3389-3511
            14134-14268         AL732564.12        4076-4210
            14269-14397         AL732564.12        5644-5772
            14398-14718         AL732564.12        6317-6637
            14719-14838         AL732564.12        7268-7387
            14839-14965         AL732564.12        7665-7791
            14966-15654         AL732564.12        8634-9322
FEATURES             Location/Qualifiers
     source          1..15654
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 21.81 cM"
     gene            1..15654
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /note="hemicentin 2"
                     /db_xref="GeneID:665700"
                     /db_xref="MGI:MGI:2677838"
     exon            1..345
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     CDS             84..15311
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /codon_start=1
                     /product="hemicentin-2 precursor"
                     /protein_id="NP_001357831.1"
                     /db_xref="GeneID:665700"
                     /db_xref="MGI:MGI:2677838"
                     /translation="MTPGAQLLPLLVAISTAVAAVVTSDAPTKTLSPATGDATLAFVF
                     DVTGSMWDDLMQVIDGASRILERSLSSRSRVIANYALVPFHDPDIGPVTLTADPVVFQ
                     RELRELYVQGGGDCPEMSVGAIKAAVEVANPGSFIYVFSDARAKDYHKKKELLQLLQL
                     KQSQVVFVLTGDCGDRTHPGYLVFEEIASTSSGQVFQLDKQQVSEVLKWVESAIQASK
                     VHLLSADHEEEGEHTWRIPFDPSLKEVTIALSGPGPEIEVRDPLGRVLQTDEGLNVLL
                     NIPDSAKVVAFKPEHPGLWAIKVYSSGRHSVRISGISNINFRAGFSMQPSLDLNHTIE
                     WPLQGVPISLVINSTGLQAPGHLESVELSHSSGRSLLTLPTQLLSNGSTHQLWAGPPF
                     HVPKERFYLKVKGKDHEGNPLLRVSGVSYSAVAPGVPLVSMAPKIHGYLQQPLLVSCS
                     VYSTLPFQLQLQRDGERLGEERYFQESGNSSWEIPRASKAEEGTYQCIAVSRAGSGRA
                     SAQIVITDPPPQLVPGPNVTVSPGETAILSCQVLGETPYNLTWVRDWRALPATTGRIS
                     QLSDLSLEVRSIIPTDGGQYQCVASNPNGVTRATTWLLVREAPQVSINARSQRFSQGV
                     EVRVSCSASGYPTPHISWSREGLALPEDSRIHVDAQGTLIIQGLAPEDAGNYSCQATN
                     EVGTDEETVTLYYTDPPSVSAVNAVVLTAVGEEAVLLCAASGVPPPRVIWYRGGLEVI
                     LAPGDSRSGTLRIPEAQERDAGLYTCKAVNELGDASAEIQLVVGNAPRLTDPPQDVTV
                     ELGKSVFLTCRATGRPPPIVTWRRGDGQALEPGRGSRTGQRDSGVLVFERVSLEDQAP
                     YVCEARNVFGKAQAEARLVVTGHAPPQIANSASVVRVLEGQPVSLTCVILAGRPLPER
                     RWLKAGSPLPPGNRHAVRADGSLHLDRALQEDAGRYSCVATNVAGSQHRDVELVVQVP
                     PRIHPTSTHHVTNEGVPASLPCIASGVPTPKITWTKETNALTTSGHYSVSRNGTLVIV
                     QPSPQDAGAYVCTATNSVGFSSQEMWLSVNTKPMIKMNGSQAVDVPLRVTVKAGEEVT
                     LDCEAQGSPTPLLTWTKDANPLLPVTNRYELLPSGSLRLAQAQVGDNGLYGCTASNPA
                     GATSRRYVLRVQVPPQVQPGPRVLKVLAGEALDLNCVAEGNPQPQLNWFKDGMALMGE
                     GAQGSVHFAAVKTSDAGLYRCEASNSAGTDTWKLELLVLEPPHWGTDETKSLLERVAG
                     ENASLPCPAQGTPKPRITWRRGPSSEPLNGRPDVAVLDEGSLFLSSVSLADSGEYECQ
                     ATNEVGSASRRAKLVVYVPPSIREEGHITNVSGLAGQPLTLECDINGFPAPEVAWLKD
                     GQLIPEASGHRLLDGSRSLHFPRIQESHSGLYSCQAENQAGSAQRDFNLAVFIPPSLL
                     GAGAAQEVLGLAGADVTLECQTSGVPTPQVEWTKDGQPILPGDPHILLQEDGQVLRII
                     SSHLGDEGQYQCVAFSPAGQQAKDFQLSIHSPPTIWGSNETGEVTVLEGHTAQLLCEA
                     RGMPSPAITWYKDGTLLAPSSEVVYSKGGRQLQLVKAQPSDAGLYTCQASNPAGITKK
                     STSLEVYVPPTIEGADGGPYLVQAVAGRPVALECVARGHPPPTISWQHEGLPVVDSNG
                     TWLEAGGALQLENPGEASGGLYSCVASSPAGEAVLQYSVEMQVPPQLLVAEGMGQVTA
                     TVGQSLDLPCQASGSPVPTIQWLQNGRPAEELAGVQLASQGTILHISHVELNHSGLFA
                     CQATNEAGTAGAEVEVSVHELPSVHIIGGENLTAPFLQPVTLQCVGIGVPTPSLRWWK
                     DGVAVATSGGNLQIEKADLRDEGVYTCSATNLAGESKKDVTLKVLVPPNIEPGPVNKV
                     VLENASVTLECLASGVPPPDVSWFKGRQPISTQRRVIVSADGRVLHIERVQLSDAGSY
                     RCVATNVAGSAGLKYGLRVNVPPRITLPPNLPGPVLLGTPFRLTCNATGTPRPTLIWL
                     KDGNPVSPEGIPGLKVFPGGQVLTVASARASDSGSYSCVAVSAVGEDRRDVILQVHMP
                     PSILGEELNMSVVVNESVTLECQSHAVPPPVLRWQKDGRPLEPHPGIRLSADKALLEV
                     DRAAVWDAGHYTCEAINQAGRSEKHFNLHVWVPPAFPSKEPYTLTVTEGQTARLSCDC
                     QGIPFPKISWRKDGQPLPGEGDSLEQVLAVGRLLYLGQAQSAQEGTYTCECSNAAGTS
                     SQEQSLEVLVPPQVTGLWEPLTTVSVIQDGNTTLACNATGKPLPVVTWQRDGQPVSVE
                     PGLRLQNQNHSLHVERAQASHAGGYSCVAENTAGRAERRFALSVLAPPHLTGDSDSLT
                     NVTATLHGSFTLLCEAAGVPAPTVQWFQEGQPISPREGTYLLAGGWMLKMTQAQEQDR
                     GLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVPEGQTAQLECNATGHPPPK
                     VTWFKDGQSLTVEDPYEMSPDGAFLWIPQANLSNAGHYSCIASNAVGEKTKHTQLSVL
                     VVPTILGVPEKNANEEVTVTINNPISLICEALAFPSPNITWMKDGSPFEASKNIQLLP
                     GTHGLQILNAQKEDAGQYTCVVTNELGEATKNYHVEVLIPPSISKDDPLGEVSVKEVK
                     TKVNSSLTLECECWATPPPSISWYKDGRPVTPSHRLSVLGEGRLLQIQPTQVSDSGRY
                     LCVATNVAGEDDQDFNVLIQVPPMFQKMGDVDAGFEPLPHEEEAQGRVTEYREIVENN
                     PAYLYCDTNAIPPPELTWYREGQPLSAADGVSVLQGGRILQLPLVQAEDAGRYSCKAA
                     NEVGEDWLHYELLVLTPPVIPGDTQELVEEVTVNASSAVSLECPALGNPAPAVSWFQN
                     GLPVSPSPRLQVLEEGQVLKVATAEVADAASYMCVAENQAGSAEKLFTLKVQVPPQIS
                     DWTTSQLTATLNSSVSLPCEVYAHPNPEVTWYKDGQPLSLGQEAFLLPGTHTLRLARA
                     QPADSGTYLCEALNAAGRDQKMVQLNVLVPPSFKQAPGGPQEAIQVRAGDKAILSCET
                     DSLPEPAVTWFKDQQPLALGQRIQGLQGGQTLEILDSQASDKGVYSCKVSNTAGEAIR
                     TFVLAIQVPPTFEKPERETVNQVAGRTLVLACDVSGIPAPTVTWLKDRLPVESSVVHG
                     VVSRGGRLQLSHLQPAQAGTYTCVAENAQAEARKDFVVSVLVPPQIQDSGMAQEHNVL
                     EKQEIRLHCEAEGQPPPDITWLKDGGLLDQHVGPHLRFYLDGSTLVLKGLRTADSGAY
                     TCVAHNPAGEDARLHTVNVLVPPTIKQQAGDTGTLVSRTGELVTMVCPVQGSPPIHVS
                     WLKDGLPLPLSQRTLLHSSGRTLRISQVQLADSGVFTCVAASPAGVADRNFTLLVLVP
                     PILEPVEFQNNVMAAQGSEVVLPCEARGSPLPLVSWMKDGEPLLPQSLEQGPGLKLES
                     VSVGDAGTYSCTAASEAGEARRHFQLTVMDPPHIEESGETSELSLTPGAHLELLCEAR
                     GIPPPNITWHKDGQALRRTENDSQAGRVLRVRDVQVDNAGLYTCLAESPAGEVEKSFR
                     VRVQAPPNVVGPRGPRSVVGLAPGQLILECSVEAEPAPEIEWHRGGVLLQADAHTHFP
                     EQGRFLKLQALSTADGGDYSCTARNRAGSTSVAFRVEIHTAPTIQSGPNTVNVSVNRT
                     TLLPCQTHGVPTPLVSWRKDGIPLHPGSPRLEFLPEGSLRIHPVLAQDAGHYLCLASN
                     SAGSDRKGLDLRVFEPPAIAPGPSNLTLTAYSPASLPCEARGSPKPLVTWWKDGQKLD
                     LRLQQGAYRLLPSNALFLTAPSPQDSAQFECVVSNEVGESRRRYQVTVHVPPTIADDQ
                     THFTVTRMAPVILTCHSTGSPTPAVSWSKAGTQLGARGSGYRILPSGALEIERALPLH
                     AGRYTCTARNSAGVARKHMVLTVQASPVVKPLPSVVQVVASEEVLLPCEASGIPQPMV
                     IWQKEGLSIPEGAHMQVLPSGQLRIMHASPEDAGNYFCIAQNSVGSAMAKTRLVVQVP
                     PVIENGLPDLSTIEGSHALLPCTAKGSPEPAITWEKDGHLVSGAEGKFTLQPSGELLV
                     KNSEGQDAGTYICTAENAVGRARRRVHLTILTLPVLTTLPGDRSLRLGDRLWLRCVAR
                     GSPTPRIGWTINDQPVTEGVSEQDGGSTLQRAAVTREDSGTYTCWAENRVGRVQAVSF
                     VHVKEAPVLQGEAFSYLVEPVGGSIQLHCVVRGDPAPDIHWTKDGLPLPISRLHFQLQ
                     NGSLTILRTKMDDAGRYQCLAVNEMGTVKKVVTVVLQSAPVFQVEPQDVTVRSGVDVE
                     LRCRATGEPVPTIEWLRAGRPLQAGRKLRALPDGSLWLEHVEAGDAGVYECVAHNHLG
                     SVTAKALLAVRGEPRGSRGSMTGVINGQEFGMATLNISVLQQGSSEAPTIWSSISQVP
                     ASVGPLMRVLVVTIAPIYWALARESGEALNGYSLTGGSFQQESQMEFSTGELLTMTQV
                     ARGLDPDGLLLVDMKINGMIPESLADGDLRVQDFQEHYVQTGPGQLFAGSTQRFLHDS
                     LPASLRCNHSIQYDETRGLQPQLVQHLRASSISSAFDPEAEALNFQLTTALQTEENEV
                     GCPEGFEPDVQGAFCVDKDECSGGPSPCSHTCRNAPGHFSCSCPTGFSLAWDHRNCRD
                     VDECAGNTHLCQEEQRCVNLLGSYNCLASCRPGFRVTADGSNCEDVDECLEQLDECHY
                     NQLCENTPGGHHCGCPRGYRQQGHSLPCLDINECLQLPTPCVYQCQNLQGSYRCLCPP
                     GQTLLRDGRTCIPLERNRQNITIVSHRSPFGPWLRSRVPRPSSSYHTWVSLRPGSGAL
                     NSVGRAWCPPGFIRQDGVCADLDECRVRSLCQHACQNTEGSYYCLCPSGYRLLPSGKN
                     CQDINECEEDGIECGPGQMCFNTRGSFQCVDTPCPTTYRQGSSPGTCFRRCSQDCSAS
                     GPSTLQYRLLPLPLGVRAHHDVARLAAFSEAGIPANRTELTVLEPDPRSPFALRQLRA
                     GQGAVYTRRALTRAGLYRLTVRAAAPRHQSVYILLIAVSPYPY"
     exon            346..416
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            417..575
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            576..698
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            699..870
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            871..977
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            978..1098
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            1099..1362
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            1363..1507
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            1508..1629
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            1630..1902
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            1903..2044
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            2045..2172
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            2173..2286
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            2287..2436
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            2437..2625
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            2626..2721
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            2722..2849
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            2850..2994
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            2995..3107
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            3108..3264
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            3265..3430
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            3431..3558
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            3559..3813
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            3814..3900
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            3901..4095
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            4096..4226
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            4227..4374
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            4375..4501
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            4502..4656
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            4657..4935
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            4936..5214
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            5215..5323
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            5324..5493
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            5494..5648
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            5649..5745
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            5746..5841
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            5842..6018
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            6019..6176
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            6177..6300
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            6301..6476
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            6477..6573
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            6574..6693
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            6694..6855
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            6856..7137
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            7138..7305
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            7306..7419
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            7420..7506
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            7507..7698
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            7699..7872
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            7873..7986
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            7987..8129
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            8130..8280
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            8281..8499
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            8500..8613
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            8614..8801
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            8802..8898
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            8899..9060
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            9061..9174
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            9175..9377
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            9378..9459
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            9460..9591
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            9592..9735
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            9736..9895
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            9896..10020
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            10021..10204
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            10205..10302
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            10303..10569
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            10570..10760
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            10761..10842
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            10843..10979
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            10980..11121
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            11122..11266
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            11267..11394
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            11395..11551
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            11552..11673
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            11674..11838
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            11839..11946
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            11947..12081
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            12082..12216
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            12217..12407
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            12408..12621
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            12622..12756
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            12757..12947
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            12948..13029
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            13030..13299
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            13300..13449
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            13450..13587
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            13588..13709
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            13710..13947
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            13948..14010
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            14011..14133
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            14134..14268
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            14269..14397
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            14398..14718
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            14719..14838
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            14839..14965
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     exon            14966..15654
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /inference="alignment:Splign:2.1.0"
     regulatory      15630..15635
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /note="hexamer: TATAAA"
     polyA_site      15654
                     /gene="Hmcn2"
                     /gene_synonym="D030068H01"
                     /note="major polyA site"
ORIGIN      
        1 ggtgaacccg ctagagcgag actgcactgc catctctcac tgcgacctgc gggtcccatc
       61 agggctgcag cctccggctc accatgacgc ctggggcgca gctcctgccg ctgctcgtgg
      121 cgatctctac agcagtggcg gcggtggtca cgtctgacgc gcccacgaag acgctgtccc
      181 ccgccacagg agacgccacc ctagccttcg tcttcgatgt caccggctcc atgtgggatg
      241 acctgatgca ggtgatcgac ggcgcctcgc gcattctgga gcgcagcctg agcagccgca
      301 gccgggtcat cgccaactat gcgctggtgc ctttccacga cccagatatt ggcccggtga
      361 ccctcacggc agacccagtg gtatttcaga gagagctgag agaactctat gttcagggag
      421 gaggtgattg cccagagatg agtgtggggg ccatcaaggc tgccgtggag gtcgccaacc
      481 caggctcctt catctacgtc ttctcggatg cccgtgccaa ggactaccac aagaagaagg
      541 agcttctgca gctcctgcag ctgaagcagt cacaggtggt ctttgtgctg actggagact
      601 gtggtgaccg cacccatcct ggctacctgg tcttcgagga gatcgcctcc accagttctg
      661 gccaggtgtt ccagctggac aaacagcagg tgtcggaggt gttaaagtgg gtggagtcag
      721 caatccaggc ctccaaagtt catctgctgt ctgcagacca tgaggaggag ggcgagcaca
      781 cgtggagaat cccctttgac cccagcctga aggaggtcac cattgcactg agcggaccag
      841 ggcctgagat tgaagtccgg gacccactgg gaagggtcct gcagacggat gaaggcctca
      901 atgtgctcct caacattcca gactcagcca aggtcgtagc ctttaagcct gagcacccag
      961 gactgtgggc catcaaggta tacagcagcg gccgccactc agtgaggata tcaggcatca
     1021 gcaacatcaa cttccgagcc ggcttctcca tgcagccctc cctggacctc aaccacacca
     1081 tcgagtggcc tttgcaaggc gtacccatct ccctggtgat caactctacg ggcctgcagg
     1141 cacctggcca ccttgagtct gtggagctct cacacagctc ggggaggtcc cttctcactc
     1201 tgcccacaca actcctctcc aatgggtcca cccatcagct gtgggctggg ccacccttcc
     1261 acgtgccgaa ggaacgcttt tatctcaagg tgaagggcaa agaccacgag gggaatcccc
     1321 tccttcgtgt ctctggagtt tcctacagtg cagtggcccc aggtgtgccg ctggtcagca
     1381 tggctcctaa gatccatggt tacctacagc agcccctgct ggtgtcctgc tctgtgtata
     1441 gcaccctccc cttccagcta cagctgcaga gagatggaga gaggctgggc gaggagcggt
     1501 actttcaaga gtcgggaaac agcagctggg agatcccgag agcctctaag gctgaggaag
     1561 gcacgtacca gtgcatagcc gtcagcagag ctgggtcagg acgagccagc gcccagattg
     1621 tcatcacaga ccctccacca cagctggtcc ctggccccaa tgtgaccgtg tccccagggg
     1681 agactgccat cctgtcatgc caagtcctag gtgaaactcc ttacaacttg acctgggtcc
     1741 gggactggcg agccttacca gccacaacag gtcggatctc ccagctgagt gacctgtctc
     1801 tggaagtccg cagcatcatt cccactgatg gtgggcagta ccagtgtgtg gccagcaacc
     1861 caaatggggt cacgagggca actacctggc tcctggtgcg agaggcccct caagtcagca
     1921 tcaatgcaag gtcccagcgc ttctcccagg gtgtggaggt gagggtcagc tgctcagcct
     1981 ctgggtaccc cacaccccat atctcatgga gccgtgaagg cctcgccttg ccagaggaca
     2041 gcagaatcca tgtggatgcc caaggcacac tcatcattca ggggttagcc cctgaggatg
     2101 ctgggaacta cagctgccag gccactaatg aagttggcac agatgaggag acagtcactc
     2161 tctactacac agatccacca tccgtgtctg ctgtcaatgc tgtggttctc acagctgttg
     2221 gggaagaggc tgtgctattg tgtgcagcat ctggggtccc cccaccccgg gtcatctggt
     2281 atcgaggagg tctggaagtg attctggctc ctggagactc taggtcgggg acactgcgga
     2341 tccctgaagc tcaggagaga gacgctggcc tctatacctg caaggctgtg aacgagctgg
     2401 gtgatgcctc tgctgaaata cagctggtgg tgggaaatgc acccaggctg acggatccgc
     2461 cccaggacgt cactgtggag ctgggcaaga gtgtcttcct cacctgccgg gccacaggcc
     2521 gcccaccccc aattgtcact tggcggcgtg gagatggcca ggccctggag cctgggaggg
     2581 ggagcagaac tggacagcga gattcaggag tcttggtctt tgaaagagtc tccctggaag
     2641 accaagcacc gtatgtgtgt gaagctcgca atgtgttcgg gaaggcccag gctgaggccc
     2701 ggctggtagt cactggacat gcacctccac agatcgccaa cagtgcttct gtcgtacgtg
     2761 tcctggaggg acagcccgtg tccctgacct gtgtcatcct ggcagggagg cccctccctg
     2821 agagacgctg gctcaaggct ggcagccctc tccccccagg caaccggcat gctgtccgtg
     2881 ctgacggcag cctacacctt gaccgagccc tgcaagaaga tgctggaaga tacagctgtg
     2941 tggccaccaa tgtggcaggc tctcagcacc gagatgtgga gctggtggtc caggtgccac
     3001 ctagaatcca tccgacttcc acccaccacg tcaccaacga aggagtgcca gcctccctcc
     3061 cctgcatagc ttcaggagtc cccaccccta aaatcacctg gaccaaggaa accaacgcct
     3121 tgactaccag cggtcactac agtgtgagca gaaatggtac cctggtcatt gtccagccat
     3181 ccccgcagga tgcaggtgcc tatgtgtgca cagccaccaa cagtgtgggc ttctccagcc
     3241 aggagatgtg gctgtctgtt aataccaagc ccatgatcaa gatgaatggc tcccaggctg
     3301 tggatgtccc tctgagagtg acagtcaagg ctggtgaaga ggtgaccctg gactgtgagg
     3361 cccaaggctc cccaactcca ctgctcacct ggaccaagga tgccaaccct ctactgcctg
     3421 tcaccaacag gtatgagctc ctcccatcag gctccctgcg cctggcacag gcccaggtgg
     3481 gtgacaatgg cctttatggg tgtacagcca gcaaccccgc gggggccaca tctcgccgct
     3541 acgtcctcag agttcaagtc ccccctcagg tgcagcctgg ccctcgggtc ctgaaggtac
     3601 tggctggaga agcccttgac ctgaactgtg tggccgaagg caacccccaa cctcagctga
     3661 actggttcaa ggacgggatg gccctgatgg gcgagggagc ccagggctct gtccactttg
     3721 ctgctgtcaa gacctctgat gctgggctgt accgctgtga ggcctccaat agcgctggca
     3781 cagatacctg gaagctggag ctccttgtgc tcgagccacc acactggggg actgacgaga
     3841 ccaagagcct gctggagcga gtggccggag agaatgccag tctgccatgt cctgcccaag
     3901 ggactccaaa gccacgaatc acatggcgga ggggcccatc ctcagagccc ctgaatggcc
     3961 ggccagatgt ggcggtgctg gatgaagggt cgctgttcct gtcctcagtc tctcttgcag
     4021 acagcgggga gtacgagtgc caggccacca atgaggtggg ctctgcatcc aggagagcca
     4081 agctggtggt ctatgtgccc cccagcatcc gggaagaggg gcacataacc aacgtgtcgg
     4141 gcctagctgg acagcccctg acgctggagt gtgacataaa cggctttcct gcccctgagg
     4201 tggcgtggct caaggatggg cagctgatcc cagaggcaag tggacatcgc ctcttggatg
     4261 gctcccggtc cctccacttc cctaggatcc aagagagcca ttctggcctc tattcctgcc
     4321 aggctgagaa tcaggcgggg agcgcccaga gagacttcaa tcttgctgtg ttcatccctc
     4381 cctccttgct gggagctggg gccgctcagg aggtgcttgg cctggctggt gctgatgtga
     4441 cattggagtg tcagacctca ggggttccca cgccccaggt ggagtggacc aaggatgggc
     4501 agcctatcct tccaggggat cctcacatcc tgctgcagga ggatggccaa gttctcagaa
     4561 ttatcagcag tcacttaggt gacgaagggc agtatcagtg tgtggccttc agcccagccg
     4621 gccagcaggc caaggacttt cagctcagca ttcactcacc acccaccatc tggggctcga
     4681 atgagacagg tgaggtgact gtcctggagg gccacaccgc acagctccta tgtgaggccc
     4741 gaggaatgcc atcccctgcc atcacctggt acaaggatgg gaccctgctg gcccccagct
     4801 cagaagtggt ttacagcaag ggcggccggc agctgcagct ggtgaaggcc cagccctccg
     4861 atgctggcct ctacacctgc caggccagca accctgcagg gattacgaag aaatccacca
     4921 gtctggaggt ttatgttcca cctaccattg agggtgctga cggagggcca tacctggtgc
     4981 aggctgtggc tgggagaccc gtggcactgg agtgtgtggc cagaggccat ccacccccta
     5041 cgatctcctg gcagcatgaa gggctgccag tggtggacag taatgggaca tggctggagg
     5101 caggaggtgc cctgcagctg gagaacccag gagaggcatc cggtggcctc tacagctgtg
     5161 tggccagcag ccccgctgga gaggctgtac tgcagtactc agtggagatg caggtgcccc
     5221 cacagctgct ggtggctgaa ggcatgggcc aggtcactgc caccgtggga cagtctctgg
     5281 atcttccctg ccaggcatca ggctccccag tgcccaccat ccaatggtta cagaatggtc
     5341 gcccagcaga ggagctggct ggggtgcagc tggcctcaca ggggaccata ctgcacatca
     5401 gccacgtgga gctgaaccac tcaggcctct ttgcctgcca ggccaccaac gaggcaggaa
     5461 cagctggggc tgaggtggag gtctctgtgc atgagcttcc ttcagtgcac atcattggtg
     5521 gggagaacct cacagcccct ttcctgcaac ctgtaaccct ccagtgtgta ggcattggag
     5581 tgcctacccc aagccttcgc tggtggaaag atggcgtggc cgtggcaacc tcagggggca
     5641 accttcagat tgagaaggca gacctgagag atgaaggtgt ctacacgtgt tcagccacca
     5701 acctggcagg ggagagcaag aaggatgtaa cactaaaggt tctggttcct cccaacattg
     5761 aaccaggccc agtcaacaag gtggttctgg agaatgcctc tgtgaccttg gagtgtctgg
     5821 cttccggtgt cccccctcca gacgtctcct ggttcaaggg tcgccagccc atctctaccc
     5881 agagacgggt gatagtgtca gctgatggaa gagttcttca tattgagcga gtccagcttt
     5941 ctgatgcagg gagctaccgc tgtgtggcga ccaatgtggc gggcagtgca gggctgaagt
     6001 atggcctacg ggtcaatgtg ccaccccgaa ttaccctgcc acccaaccta ccaggcccag
     6061 tactgcttgg cacacccttc cgcctgacct gtaatgccac tggcaccccc cgccccaccc
     6121 tgatatggct gaaggatgga aaccctgtgt ctcctgaagg aatccctggc ctcaaggtct
     6181 tccccggagg acaggtcctc actgtggcca gtgcccgtgc ctctgattcg ggcagctact
     6241 cctgtgtagc agtgagtgct gtgggtgagg atcgccggga tgtcatcctg caagttcaca
     6301 tgccccccag catcctcgga gaagagctaa acatgtccgt cgtcgtaaat gagtcagtga
     6361 ccctggagtg ccagagccat gcagtgccac cacccgtgct gagatggcag aaggacggga
     6421 gacccctgga gcctcaccct gggatccgcc tctctgcaga caaggccttg ctggaggtgg
     6481 accgagcggc ggtgtgggat gcaggccact acacctgtga agctattaac caggcaggcc
     6541 gctctgagaa acacttcaac ttgcatgtct gggtccctcc agcgttcccc tcaaaggagc
     6601 cctacactct cactgtgact gagggacaga ccgccagact gtcgtgtgac tgccagggca
     6661 ttcctttccc caagatctca tggaggaaag atggtcagcc tctgcctggg gagggggaca
     6721 gcctggaaca ggtgttggca gtcgggaggc tgctgtacct gggacaggcc cagtcggccc
     6781 aggaggggac atatacctgt gaatgcagca atgcagccgg gaccagcagc caggagcagt
     6841 cgctggaggt tctggttcct cctcaggtca ctggcctctg ggagcccctc acaacagtct
     6901 ccgtgatcca ggatggaaac accaccctgg cctgtaatgc cacagggaag cccctcccag
     6961 tggtgacatg gcagagggat ggtcagcctg tctcggtgga acccggcttg cggcttcaga
     7021 atcagaacca cagcctacac gtggaacggg ctcaggcctc ccacgccggc ggctacagct
     7081 gtgtggctga gaatacagct gggcgtgccg agaggaggtt tgcactgtct gtgctggcac
     7141 ctcctcatct tactggagac tcagactcac tgaccaatgt cactgctacc ttacacggct
     7201 ccttcacact gctctgtgaa gctgcagggg tcccggcccc aacagtccag tggtttcagg
     7261 aaggacagcc aatcagcccc agagagggca cctatctctt ggcaggtggc tggatgctga
     7321 agatgaccca ggcacaggag caggacagag gcctctattc gtgcctggcc agcaatgagg
     7381 ctggggaggc acggaggaac ttcagtgtag aggtcttggt tcctcccagc attgaaaatg
     7441 aagacttgga ggaagtgatc aaggtgcctg agggacagac tgcccagctg gagtgcaacg
     7501 ccacaggcca cccaccgccc aaggtcacat ggttcaaaga tggccagtcc ctgactgttg
     7561 aagaccctta tgagatgtcc ccagatgggg ccttcctgtg gatcccccag gccaatctgt
     7621 ccaatgctgg ccactattct tgcattgcta gcaatgctgt gggggagaag accaaacaca
     7681 cacagctcag tgtcctggtg gttcccacca tcctgggagt gccagagaag aatgccaacg
     7741 aggaagtgac tgtgaccatc aacaatccta tttccttgat ctgtgaggct ctggcctttc
     7801 catcccccaa tatcacctgg atgaaggatg ggtcgccctt tgaggcctca aaaaacattc
     7861 agctcctccc aggtacccac ggactacaga tcctgaatgc ccagaaggaa gatgccggcc
     7921 agtacacctg tgtagtcacc aatgagctgg gggaggcgac aaagaactac catgtggaag
     7981 tgctcattcc cccttccatc tccaaagatg accccttggg ggaggtcagc gtgaaggaag
     8041 tgaagaccaa ggtcaacagc tctctgaccc tggagtgtga atgctgggcc acacccccgc
     8101 cctccatcag ctggtacaaa gacggaaggc ctgtgacccc cagccaccgg ctcagtgtcc
     8161 tgggggaggg gcggctgctc cagatccaac ccacacaggt ctctgactct ggccgatacc
     8221 tgtgtgtggc caccaatgtg gctggcgagg acgaccagga cttcaatgtt ctcatccaag
     8281 tgccccctat gttccagaag atgggcgatg ttgatgcagg ctttgagccc ctgccccatg
     8341 aggaggaggc ccagggcagg gtgacagagt acagagagat tgtggagaac aacccagctt
     8401 acctgtactg cgataccaat gccattccac caccagagct cacgtggtac agggagggtc
     8461 agcccctgtc agctgctgat ggggtctcgg tactgcaagg aggccgaatc ctgcagctgc
     8521 ctcttgtgca ggcagaggat gcgggcaggt actcctgcaa ggctgccaat gaggtgggcg
     8581 aggactggct acattacgaa ctactggtgt tgacaccacc agtgatcccg ggagacacac
     8641 aggagctggt agaggaggtg acagtgaacg ctagcagtgc tgtcagccta gagtgcccag
     8701 ccctggggaa cccagcacct gctgtgtcat ggttccagaa tgggctgcct gtgtccccca
     8761 gcccacggct gcaggtccta gaggagggac aggtcttgaa ggttgccact gcagaggtag
     8821 ccgatgccgc cagctacatg tgtgttgcag agaaccaggc aggctctgca gagaaactct
     8881 ttaccctcaa ggtccaagta ccgccacaaa tctcagactg gaccaccagc cagctcaccg
     8941 ccaccctcaa cagcagtgtc tccctcccct gtgaagttta tgctcaccca aaccctgagg
     9001 tcacatggta caaggatggc cagcctctct ccctgggaca agaggctttc ctcctccccg
     9061 gtacccacac tctgcggctg gcacgagcac agccagctga ctccgggacc tacttgtgtg
     9121 aagccctcaa cgccgcaggc cgagaccaaa agatggtaca gctcaacgtt ctcgttcccc
     9181 ccagctttaa acaggctcct ggaggccccc aggaggctat ccaggttaga gcaggggaca
     9241 aagccatcct aagctgcgag acagactcac tcccagagcc agctgtgacc tggttcaagg
     9301 accagcagcc cctagccctg gggcagcgga ttcagggtct acaaggtgga caaacactgg
     9361 agatcctgga ctcacaggca tcagataagg gtgtgtacag ctgcaaagtt agcaatacag
     9421 ctggagaggc catccggacc tttgtccttg ccatccaagt gcctccaaca tttgagaagc
     9481 ccgagaggga gacagtgaac caggtagctg ggcggaccct agtcctggct tgtgatgtgt
     9541 ccggaatccc tgctcccact gtgacttggc tgaaggacag attacccgtg gagagcagcg
     9601 tggtacacgg agtggtctcc cgaggtggcc gcctccagct gagtcacctg cagccagccc
     9661 aggccggtac ctacacttgt gtggctgaga acgcccaggc agaggcccgc aaagactttg
     9721 tagtgtctgt cctagtgcct ccccagatcc aggactcagg catggcacaa gaacacaatg
     9781 tgttggagaa acaggagatt cggctgcact gtgaggctga aggccagcca ccaccagata
     9841 taacctggct gaaggacggt ggcctgttgg accagcacgt gggacctcac ctccggttct
     9901 atctggacgg cagtaccctg gtgctgaagg gcctaagaac agcggactcg ggtgcctaca
     9961 cctgtgtggc ccacaaccca gctggggagg atgccaggct acacacggtg aatgtactgg
    10021 ttcctcccac catcaagcaa caagctggtg acaccgggac cctggtgagc aggactggag
    10081 agctggtgac catggtgtgc cctgtccaag gatccccacc cattcacgtg agctggctca
    10141 aggacggcct gccccttcca ctctcccagc gcaccctcct ccacagctcc ggccgcaccc
    10201 tcaggatctc tcaggtgcag ctggcagatt caggcgtctt cacctgtgtg gctgcaagcc
    10261 cagctggtgt ggctgacagg aacttcacct tgctagtact cgtgcccccc atcctggaac
    10321 cagtggagtt tcagaacaac gtgatggctg cccaaggctc tgaagtagtc cttccgtgtg
    10381 aggcccgggg aagccccctg cctctcgtgt catggatgaa agatggggag cctttgttgc
    10441 cccagagcct tgagcagggg cctggcctga agctggaatc agtgagtgtt ggtgacgcag
    10501 ggacctactc ctgcacggca gcaagcgagg caggggaggc caggaggcac ttccagctga
    10561 cagtgatgga tccccctcac attgaggaat ctggtgagac ttcagagctg tcactgacac
    10621 ccggtgccca cctggaactc ctgtgtgagg cccgaggcat ccctccaccc aacatcactt
    10681 ggcataaaga cgggcaggcc ctgcgcagga cggaaaatga cagccaagct ggccgggtgc
    10741 tccgggtgcg ggatgtacag gtggacaatg ctgggctgta tacctgcctg gctgagagcc
    10801 ctgcaggtga agttgagaag agcttccggg tcagggttca agcccctcca aatgttgttg
    10861 ggccccgggg tccccgctct gtggttggct tggctccagg gcagctgatc ctggagtgct
    10921 ccgtggaggc agagccagca ccagagattg agtggcatcg aggtggtgtc ctgcttcagg
    10981 cagatgccca cactcacttt ccagagcagg gcagattcct caagctgcag gcgctgagca
    11041 ccgcggatgg tggggactac agctgcacag cccgcaacag ggcaggcagc accagcgtgg
    11101 ctttccgtgt ggagatccac acggcaccca ccatccaatc aggaccgaac actgtgaacg
    11161 tctcagtgaa ccgcacaacc ctgctgccct gccagaccca cggtgtgccc acgcccctcg
    11221 tgagctggag gaaggatggg atccctctgc accctgggag ccccaggcta gagtttctgc
    11281 ccgagggatc actgcggatt catccagtcc tggcacagga tgccggacac tacctctgcc
    11341 tagcatccaa ctctgctggc tccgaccgga aaggcctaga cctcagagtc ttcgagcccc
    11401 cggccattgc tcctggcccc tccaacctga ccctgacggc ctacagccca gcctcgctgc
    11461 cctgtgaagc cagaggctct cccaagccct tggtgacctg gtggaaggat gggcagaagc
    11521 tggacctccg cctacagcaa ggcgcctacc ggcttctgcc ttccaatgcc ctgttcctca
    11581 ccgctcccag ccctcaggac tcagcccagt ttgagtgtgt cgtgagcaat gaggtgggag
    11641 agtcccgcag gcgctaccag gtgaccgtcc atgtgcctcc caccattgcg gacgaccaga
    11701 cacatttcac ggtgaccagg atggcacctg tgatcctcac gtgccacagc acagggtcac
    11761 caaccccagc cgtgtcctgg agcaaggcag gcacccagct gggagcaagg ggcagcggct
    11821 accgcatctt gccctctgga gccctggaga ttgagcgggc cctccctctc catgctggcc
    11881 ggtacacctg cacagctcga aactctgcag gggtggcccg caagcacatg gtcctcacag
    11941 tgcaagcctc ccctgtggta aagccactcc ccagcgtggt tcaggttgtg gcatcggagg
    12001 aggtgctgct gccctgtgag gcctctggca tcccccagcc aatggtcatc tggcagaagg
    12061 agggtctcag catccctgaa ggagctcata tgcaggtcct ccccagcggc cagctgcgga
    12121 tcatgcacgc cagcccagag gatgctggga actacttctg cattgcccag aacagcgtgg
    12181 gcagtgccat ggcgaagacc aggctggtgg tgcaagtccc gcctgtgatt gagaatggcc
    12241 tcccagattt gtccaccatt gagggctccc acgccctcct gccctgcaca gccaagggca
    12301 gccctgaacc agccattacc tgggaaaagg atggccacct ggtatctgga gctgagggga
    12361 agtttaccct gcagccttcc ggggagctcc tggtgaagaa ctctgagggc caggatgcag
    12421 gcacttacat ctgcactgca gaaaatgccg tgggccgtgc ccgacgccgc gtgcatctca
    12481 ccatcctgac gctgcctgtc ctcaccacct tgcctgggga ccgaagcctg cgtcttgggg
    12541 acaggctatg gcttcgctgt gtggccaggg gcagcccaac accccgcatt ggctggacca
    12601 tcaatgacca gcctgtcaca gagggggtgt ctgagcagga cgggggcagc acactgcagc
    12661 gggcagccgt caccagagag gacagcggca catacacgtg ctgggccgag aacagagttg
    12721 gtcgtgtgca ggctgtcagc ttcgtccacg tgaaggaggc tccagtccta caaggggagg
    12781 ccttctctta cctggtagaa cctgtagggg gcagcatcca gctacactgt gtggttcgtg
    12841 gagacccagc tccagacatc cactggacca aagatggcct tccactgccc atcagccgcc
    12901 tccacttcca gctacagaac ggctccctga ccatcctcag gaccaagatg gacgacgcgg
    12961 gacggtacca atgcctggcc gtgaacgaga tgggcaccgt gaagaaagtg gtgacagttg
    13021 tgcttcagag tgccccagtg ttccaggtgg agcctcagga cgtgacagtg aggtccggag
    13081 tggatgtgga actgcgatgc cgggccactg gagagcctgt gcccacaatc gagtggctac
    13141 gggcaggcag gccgctacag gctggccgga agctccgggc cctgccagat ggaagcctgt
    13201 ggctggagca tgtggaagct ggagatgctg gagtgtatga gtgtgttgct cacaatcatc
    13261 tgggctctgt cacagccaag gcgttgctgg ccgtaagagg ggagccccgg ggcagccggg
    13321 gcagcatgac tggagtcatc aatggtcagg aatttggaat ggctactctc aacatcagtg
    13381 tgctacagca gggcagctct gaggctccaa ccatctggag cagcatcagt caagtcccag
    13441 caagtgtggg gcctctaatg cgggtgctgg tggtcacgat tgcccccatc tactgggccc
    13501 tggctagaga gagcggagag gccttaaatg gctactctct gacgggtggc agcttccagc
    13561 aggagtcaca gatggaattt tctacagggg agctactcac aatgacccag gtggctcggg
    13621 gcctggatcc tgatggactc ctgctcgtgg acatgaaaat caatggcatg atcccagaga
    13681 gcctggctga cggagatctg cgagtacagg acttccagga gcactacgtg cagacagggc
    13741 ctggccagct atttgcgggc tccacacagc gtttcctcca cgacagcctc ccagcctccc
    13801 tgcgctgcaa tcacagcatc cagtatgatg agacccgggg cctccagccc cagctggtgc
    13861 agcatcttcg ggcctcttct atcagctcgg cctttgaccc tgaggcagag gccctgaact
    13921 tccagcttac cacagccctg caaacagagg aaaatgaagt tggctgtccc gagggctttg
    13981 agccggatgt gcagggagca ttttgtgtgg acaaggacga atgctcagga ggtcccagcc
    14041 cctgctctca tacctgccgc aatgctcctg gtcatttctc ctgctcctgc cccactggct
    14101 tctccctggc ttgggaccac aggaattgta gagatgtgga tgagtgtgcg ggcaacaccc
    14161 acctctgcca ggaggaacag cgctgtgtga acctgcttgg atcctataac tgcctcgctt
    14221 cctgtagacc tggcttccgg gtaactgctg acggaagcaa ctgtgaagat gtggatgaat
    14281 gtctagaaca gctggatgag tgtcactaca atcaactctg tgagaacact ccaggtggcc
    14341 accactgtgg ttgtcccaga gggtaccgcc aacagggtca cagcctgcct tgcctagaca
    14401 tcaacgagtg cctacagctg cccacaccct gtgtctacca gtgtcagaac ctccagggca
    14461 gctaccgatg cctgtgccca ccaggccaga ctctcctacg ggatggcagg acctgtatcc
    14521 ccctggaacg gaaccgtcaa aacattacca ttgtcagcca ccggagccca tttgggccct
    14581 ggctgcggtc tcgggtaccc aggcccagta gttcctacca cacctgggtc tccctccggc
    14641 ctggttctgg ggccctgaat agtgtgggcc gggcctggtg cccacctggc ttcataaggc
    14701 aggatggcgt gtgtgcagac cttgatgagt gccgtgttag gagcctgtgt cagcatgcct
    14761 gccaaaacac agagggtagc tactattgcc tgtgcccctc tggctaccgc ctccttccca
    14821 gcgggaagaa ctgccaggac atcaacgagt gtgaggaaga tggcatcgag tgtgggcctg
    14881 gccagatgtg cttcaacacc cgaggcagct tccagtgtgt agacacgccc tgtcctacca
    14941 cctaccggca gggctccagc cccgggacct gcttccgccg ctgctctcag gactgcagcg
    15001 ccagcggccc gtctacactg cagtaccgcc tgctgccgct gcccctcggc gtgcgcgccc
    15061 accacgacgt ggcccgcctg gccgccttct ccgaggctgg catccctgcc aaccgcacgg
    15121 agctcaccgt gctggagccc gacccacgca gccccttcgc tctccgccag ctacgcgctg
    15181 gacaaggcgc ggtctacacc cgcagagcgc tcacccgcgc cgggctctac cgcttgactg
    15241 tgcgcgcagc ggcaccccgc caccagagcg tctacatcct gctaatcgca gtgtcgcctt
    15301 acccgtactg aggccagagc tgcagatcca ccctgacctc gcagagagga acagagtggc
    15361 ccttgcccat gacacctaca gtgacagaga acatcctctt ctcccgcccc cgtgcgtcag
    15421 tgagatcttt ggtaaacact gctgtgcgca gagccttgac cccagggcag agaccgctgc
    15481 ccctttgatg gcaaagccaa tgggtcaggc ctgagtcccg tctttcctca gatctcagcg
    15541 gggagctggg caagatctca gtggtccagg acagacccag taggggtgga agcgactggc
    15601 actgtcctga ccacatggaa tgtgtatagt ataaaaaaaa ttttttttta ctga
//
