LOCUS       NM_009210               4956 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus helicase-like transcription factor (Hltf), transcript
            variant 1, mRNA.
ACCESSION   NM_009210
VERSION     NM_009210.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4956)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 4956)
  AUTHORS   Kaur,G., Helmer,R.A., Martinez-Marin,D., Sennoune,S.R.,
            Washburn,R.L., Martinez-Zaguilan,R., Dufour,J.M. and Chilton,B.S.
  TITLE     Helicase-like transcription factor (Hltf)-deletion activates
            Hmgb1-Rage axis and granzyme A-mediated killing of pancreatic beta
            cells resulting in neonatal lethality
  JOURNAL   PLoS One 18 (8), e0286109 (2023)
   PUBMED   37624843
  REMARK    GeneRIF: Helicase-like transcription factor (Hltf)-deletion
            activates Hmgb1-Rage axis and granzyme A-mediated killing of
            pancreatic beta cells resulting in neonatal lethality.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4956)
  AUTHORS   Li,J., Cheng,C., Xu,J., Zhang,T., Tokat,B., Dolios,G.,
            Ramakrishnan,A., Shen,L., Wang,R. and Xu,P.X.
  TITLE     The transcriptional coactivator Eya1 exerts transcriptional
            repressive activity by interacting with REST corepressors and
            REST-binding sequences to maintain nephron progenitor identity
  JOURNAL   Nucleic Acids Res 50 (18), 10343-10359 (2022)
   PUBMED   36130284
REFERENCE   4  (bases 1 to 4956)
  AUTHORS   Helmer,R.A., Martinez-Zaguilan,R., Kaur,G., Smith,L.A., Dufour,J.M.
            and Chilton,B.S.
  TITLE     Helicase-like transcription factor-deletion from the tumor
            microenvironment in a cell line-derived xenograft model of
            colorectal cancer reprogrammed the human
            transcriptome-S-nitroso-proteome to promote inflammation and
            redirect metastasis
  JOURNAL   PLoS One 16 (5), e0251132 (2021)
   PUBMED   34010296
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 4956)
  AUTHORS   Dhont,L., Mascaux,C. and Belayew,A.
  TITLE     The helicase-like transcription factor (HLTF) in cancer: loss of
            function or oncomorphic conversion of a tumor suppressor?
  JOURNAL   Cell Mol Life Sci 73 (1), 129-147 (2016)
   PUBMED   26472339
  REMARK    Review article
REFERENCE   6  (bases 1 to 4956)
  AUTHORS   Hishiki,A., Hara,K., Ikegaya,Y., Yokoyama,H., Shimizu,T., Sato,M.
            and Hashimoto,H.
  TITLE     Structure of a Novel DNA-binding Domain of Helicase-like
            Transcription Factor (HLTF) and Its Functional Implication in DNA
            Damage Tolerance
  JOURNAL   J Biol Chem 290 (21), 13215-13223 (2015)
   PUBMED   25858588
REFERENCE   7  (bases 1 to 4956)
  AUTHORS   Suzuki,T., Li,W., Zhang,Q., Novak,E.K., Sviderskaya,E.V.,
            Wilson,A., Bennett,D.C., Roe,B.A., Swank,R.T. and Spritz,R.A.
  TITLE     The gene mutated in cocoa mice, carrying a defect of organelle
            biogenesis, is a homologue of the human Hermansky-Pudlak syndrome-3
            gene
  JOURNAL   Genomics 78 (1-2), 30-37 (2001)
   PUBMED   11707070
REFERENCE   8  (bases 1 to 4956)
  AUTHORS   Zhang,Q., Ekhterae,D. and Kim,K.H.
  TITLE     Molecular cloning and characterization of P113, a mouse
            SNF2/SWI2-related transcription factor
  JOURNAL   Gene 202 (1-2), 31-37 (1997)
   PUBMED   9427542
REFERENCE   9  (bases 1 to 4956)
  AUTHORS   Gong,X., Kaushal,S., Ceccarelli,E., Bogdanova,N., Neville,C.,
            Nguyen,T., Clark,H., Khatib,Z.A., Valentine,M., Look,A.T. and
            Rosenthal,N.
  TITLE     Developmental regulation of Zbu1, a DNA-binding member of the
            SWI2/SNF2 family
  JOURNAL   Dev Biol 183 (2), 166-182 (1997)
   PUBMED   9126292
REFERENCE   10 (bases 1 to 4956)
  AUTHORS   Osborn,M., Johnsson,N., Wehland,J. and Weber,K.
  TITLE     The submembranous location of p11 and its interaction with the p36
            substrate of pp60 src kinase in situ
  JOURNAL   Exp Cell Res 175 (1), 81-96 (1988)
   PUBMED   3126079
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY007037.1, BC059240.1 and BB007413.1.
            
            On Dec 3, 2013 this sequence version replaced NM_009210.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the functional protein.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660813.18706.1, BC057116.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849381, SAMN00849388
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-31                BY007037.1         8-38
            32-4946             BC059240.1         1-4915
            4947-4956           BB007413.1         284-293
FEATURES             Location/Qualifiers
     source          1..4956
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="BALB/c"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 6.15 cM"
     gene            1..4956
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /note="helicase-like transcription factor"
                     /db_xref="GeneID:20585"
                     /db_xref="MGI:MGI:1196437"
     exon            1..197
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     CDS             178..3189
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /EC_number="2.3.2.27"
                     /note="SWI/SNF-related matrix-associated actin-dependent
                     regulator of chromatin subfamily A member 3; TNF-response
                     element-binding protein; sucrose nonfermenting protein
                     2-like 3; RING-type E3 ubiquitin transferase HLTF"
                     /codon_start=1
                     /product="helicase-like transcription factor"
                     /protein_id="NP_033236.2"
                     /db_xref="CCDS:CCDS17261.1"
                     /db_xref="GeneID:20585"
                     /db_xref="MGI:MGI:1196437"
                     /translation="MSYTFTRGPVWKYSQSVQYGSHENIPRLSYSTFLPHFEFQDIIP
                     PDDFLTSDEEQDLVLFGTMRGQVVGLRYYTGVVNNNEMVALQREPNNPYDKNAIKVNN
                     VNGNQVGHIKREIAAAVAYIMDNKLAQVEGVVPFGASNTFTMPLYMTFWGKEENRNVV
                     LEQLKKHGFKLGPTPKTLGSSLENAWGSGRAGPSYSRPAHVAVQMTTDQLKTEFDKLF
                     EDLKEDDRTVEMEPAEAIETPLLPHQKQALAWMIARENSKELPPFWEQRNDLYYNTIT
                     NFSVKERPENVHGGILADDMGLGKTLTAIAVILTNFDDGRPLLSKRGKKNHPGKEYKD
                     ETIKRRGSNMDKKEDGHSESSTCGEEPSISGTPEKSSCTLSQLSSVCPKRRKISVQYI
                     ESSDSEEIETSELPQKMKGKLKNVQLNTKSRVKGSSKVKEDSKFALTFFASATQRKML
                     KKGMSMMECSEACDTGERTRATLIICPLSVLSNWIDQFGQHVKSEVHLNFYVYYGPDR
                     IRDSAWLSKQDIILTTYNILTHDYGTKDDSPLHSIKWLRVILDEGHAIRNPNAQQTKA
                     VLELEAERRWVLTGTPIQNSLKDLWSLLSFLKLKPFIDREWWYRIIQRPVTTGDEGGL
                     RRLQSLIKNITLRRTKTSKIKGKPVLELPERKVFIQHITLSEEERKIYQSVKNEGKAA
                     IGRYFTEGTVLAHYADVLGLLLRLRQICCHTHLLTNGMSSSGPSRSDTPEELRKMLIE
                     KMKIILSSGSDEECAICLDSLTFPVITHCAHVFCKPCICQVIHSEQPHAKCPLCRNEI
                     HGDNLLECPPEELACDSDKESSMEWKSSSKINALMHALIELRTKDPNIKSLVVSQFTT
                     FLSLIETPLKASGFVFTRLDGSMAQKKRVESIQRFQNTEAGSPTIMLLSLKAGGVGLN
                     LCAASRVFLMDPAWNPAAEDQCFDRCHRLGQKQEVIITKFIVKDSVEENMLKIQNTKR
                     DLAAGAFGTKKTDANDMKQAKINEIRTLIDL"
     exon            198..405
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            406..572
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            573..706
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            707..804
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            805..879
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            880..1071
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            1072..1167
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            1168..1234
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            1235..1328
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            1329..1408
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            1409..1453
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            1454..1534
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            1535..1632
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            1633..1776
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            1777..1915
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            1916..2051
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            2052..2231
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            2232..2356
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            2357..2535
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            2536..2661
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            2662..2774
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            2775..2955
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            2956..3036
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     exon            3037..4956
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4931..4936
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /note="hexamer: AATAAA"
     polyA_site      4950
                     /gene="Hltf"
                     /gene_synonym="P113; Smarca3; Snf2l3"
                     /note="major polyA site"
ORIGIN      
        1 ggtttctcag actgttgcag gaaggagtgg tgtggacacg tctcaccggg cggacgcggc
       61 ctggcggttc tgatttggat tccggcgcct gggccacgac gccttgagga gctttatcag
      121 gctgtctggg aagatctggg gagcccaggg catcccgaag tcaccccgcc ccgcgccatg
      181 tcctatacgt tcacgagggg tcctgtttgg aagtattcgc agtctgtcca gtatggatca
      241 cacgaaaata ttccaagact ttcatactca actttcttgc cacattttga attccaagac
      301 attattcctc cagatgactt cctaacgagt gatgaagagc aagatttggt tttatttgga
      361 actatgagag gacaagttgt tggactacgc tattacacag gagttgtaaa taataatgaa
      421 atggttgctt tacaacgaga gcctaataat ccctatgata agaatgctat taaagtaaat
      481 aatgtgaatg gaaatcaggt tggccatata aagagagaga ttgcagctgc cgtggcctat
      541 atcatggaca acaaattggc acaagtggaa ggtgtagttc cttttggtgc aagtaatact
      601 tttaccatgc ctctttatat gactttctgg ggaaaagaag aaaatagaaa cgtggtttta
      661 gagcagttga agaaacatgg atttaagttg ggtcccacac caaagacttt agggtcgagt
      721 ttggagaacg catggggctc tggaagagct ggaccaagct atagtaggcc ggctcatgtg
      781 gcagtacaga tgacaactga ccagctcaaa acggaatttg acaaattatt tgaagattta
      841 aaagaagatg atagaactgt tgaaatggaa ccagctgagg ctattgaaac accgttgctt
      901 ccacaccaaa aacaagctct agcttggatg atcgcacgag agaacagtaa agaactacca
      961 ccattctggg aacagcgcaa tgacttatat tataatacaa taacaaattt ttctgtgaag
     1021 gaacgaccgg aaaatgttca tggaggaatt ttagcggatg atatgggttt gggcaaaact
     1081 cttactgcta ttgctgtcat tcttaccaac tttgatgatg gcaggcctct tctcagtaag
     1141 agaggcaaga agaatcatcc aggaaaggaa tacaaggatg agaccattaa acgcagagga
     1201 agtaatatgg acaagaagga agatggacac tcagagtcat ccacgtgtgg tgaagaaccc
     1261 agtatttcag gaactccgga gaagagtagc tgtactctgt cgcagctgtc tagcgtctgc
     1321 cctaagagaa gaaaaatttc tgtacagtac attgaaagta gtgattcaga ggaaatcgag
     1381 acaagcgaac tgccccagaa aatgaaaggc aagctgaaaa atgtacagtt aaatactaaa
     1441 agtagagtaa aaggatcatc taaggttaag gaagattcaa aatttgcact tacttttttt
     1501 gcctctgcaa cacaaaggaa aatgttgaaa aaaggcatgt ctatgatgga gtgctcagag
     1561 gcatgtgaca ctggagagag gacaagagca acactgatca tctgtccact ctctgtgctc
     1621 agcaactgga ttgaccagtt tggacaacat gtaaaatcag aagtgcactt gaatttttat
     1681 gtttattatg gtcctgatcg tattagagat tcagcctggc tttcaaaaca ggatattatt
     1741 ttgactactt acaatatttt aactcatgat tatggaacta aagatgatag tccattgcat
     1801 agcatcaagt ggttaagggt gatcctggat gaaggccatg ccattcgaaa tccaaacgct
     1861 cagcagacaa aagctgtact tgagttagag gcagaaagaa gatgggtatt gacaggtact
     1921 cctatccaga attctttaaa ggacttgtgg tctcttctgt ccttcttaaa acttaagcca
     1981 tttattgata gagagtggtg gtataggatc atacagcgtc ctgtcactac aggagatgag
     2041 ggaggactta ggcgtttaca gtccttaata aaaaatatca cgcttagaag aacaaagaca
     2101 agcaaaatta aagggaaacc tgttttggag ttgccagaaa ggaaagtatt tattcagcac
     2161 attactctgt cagaagaaga gagaaagatt tatcagtctg ttaaaaatga aggcaaagct
     2221 gccattggaa ggtattttac tgaagggact gtccttgcac actatgcaga tgtcttgggt
     2281 cttctgctta gattgcggca gatttgttgc catacccatc ttcttacaaa cggaatgtct
     2341 tcaagtggcc cctccagaag tgacacgcct gaagagctga gaaagatgtt aatagagaag
     2401 atgaagataa ttctgagctc tggttcagat gaggaatgtg caatctgcct ggattcctta
     2461 acatttcctg tgataaccca ctgtgcacac gtgttctgta aaccttgtat ctgtcaggtc
     2521 attcacagtg agcagccaca tgcaaagtgt cctttgtgca gaaatgagat acatggagat
     2581 aatctattag aatgtcctcc cgaagaattg gcatgtgaca gtgacaaaga gtccagtatg
     2641 gaatggaagt ccagctcaaa gattaatgct ctaatgcatg ctttgattga attacggaca
     2701 aaggacccca acataaaaag tttagttgtt tctcagttta ccacattctt gtctttaata
     2761 gaaacacctc ttaaagcctc aggatttgtg tttactcgtt tagatggttc catggctcaa
     2821 aagaaaagag ttgaatcaat tcagcgtttt caaaacacag aagcaggatc tcctacgata
     2881 atgctactgt ccttaaaagc aggtggagtt ggcttgaatc tctgcgcagc ttctcgagtg
     2941 ttcttaatgg atcccgcctg gaatcctgct gcagaagatc agtgctttga ccggtgccat
     3001 cgacttggcc agaagcaaga ggtgatcatc acaaaattca ttgtgaagga ctctgtggaa
     3061 gaaaatatgt tgaaaataca gaacacgaag cgagaccttg cagctggagc ctttggcact
     3121 aagaaaacag acgccaatga catgaaacaa gctaaaatca acgaaatcag aactttaatt
     3181 gacttgtaac ttgtggggtg tttctaaggt cagtttgaac agacacttaa gtcttacaga
     3241 tgaaaaatac atatttaagg atggcatcta gagaatactt tatggggggc atattttatg
     3301 ttaatacagt agtgttactg acacatcttc tatacctgaa tctcttttta tgatacttca
     3361 cacagcagtg agttccattg taaaccggcc tgagacacat gtgcatagag ggccctttgc
     3421 tctccaggtt ggcattccct tgctgagggt attttcctac atttcccatg tttcccacat
     3481 cttcactgaa gtgtggttga agcttctact tgtaaccact tactcaccaa agccttttgg
     3541 taatgattca gtgaatctac agtccttgta aattatgaac aagtatatac agactataag
     3601 aaagatttta ctggatgttc aaaaattata cttgcattca taactaaacc ttgactaaaa
     3661 caccaaagtt cagagggcaa gttaattttt ctttgttgag atataacaaa tatgtgactt
     3721 tccatatgtg tttagagaaa atttagagaa aaaaaaaagc attgtgtgtt cattttagtg
     3781 aagtggtgca ttcattattt aaatgtgatg atagaggcac aaggtgtaaa tggtatgtag
     3841 gggtgaagga accagttcta cctggtttgt cttgaatgct tatattatgt aatttaaata
     3901 gatatttttg taagtgctct ctatttatgt aggtgttttg gaaatccaac tttataaatg
     3961 taatacagag actactgctg aacctgagaa gtgtgataat caggatggaa attgggttgg
     4021 ataaccttca aagttcaact cttaaagaca ttttaatccc gaatctaaaa atgcctttgt
     4081 gagtttagaa tccgaattta actttggaat tttattaatt gatctcttca tttttttaaa
     4141 cccttttttg ggaagttaat gactatgact catagttaaa acaaagacgc agtcagggta
     4201 tataacaata gctttctttt ctgttgttgt ttttgaatcc agagacaaga tgactaagaa
     4261 gaagctttat ggcttatgat ataaactgaa gaacaactga gactgtattt atgctctgag
     4321 agtcttacct gactaagaga gatgatagat acccttctaa atcctcacag aatcctcccc
     4381 agcctgttag tcctccgagg ggacaggact agccggcaag catcttctca gctcccttgc
     4441 tcgggcagcc aggcgaggca gagtagcatt caggtcaggt tttctgtagc ggtgaaagtg
     4501 gaataactgg gagtggcctg cttgggtgag tagcccatag gatttgtagg actagtatca
     4561 catacaaatc aagtctcatt atgtatggca ttggagttct ttagttccta tacacagtga
     4621 aattaagtgt aaactagtta tggcccaaat aaacaagaaa gaaactcagt ttactcattt
     4681 taattacaaa taaactgagg ttccaaagtg aaggccatgt gcgtcttgtc cagaaaacta
     4741 cagagctatc tatgctttaa aacatgagaa caatcaaatt tggtgttaat aaaaaaagtg
     4801 aattctaaga tatatgaacc cctgggatga gggatgctgc gctctgctgt tttactactt
     4861 agaaatgtac tgaaaatatt atatttcaaa ttgtgtttcc aactggattc ttctttaaat
     4921 taaaaaaatc aataaaaatc taaaaattta ccttct
//
