LOCUS       NM_010657               9021 bp    mRNA    linear   ROD 17-SEP-2024
DEFINITION  Mus musculus human immunodeficiency virus type I enhancer binding
            protein 3 (Hivep3), mRNA.
ACCESSION   NM_010657 XM_622355
VERSION     NM_010657.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9021)
  AUTHORS   Li,N., Shi,B., Li,Z., Han,J., Sun,J., Huang,H., Yallowitz,A.R.,
            Bok,S., Xiao,S., Wu,Z., Chen,Y., Xu,Y., Qin,T., Huang,R., Zheng,H.,
            Shen,R., Meng,L., Greenblatt,M.B. and Xu,R.
  TITLE     Schnurri-3 inhibition rescues skeletal fragility and vascular
            skeletal stem cell niche pathology in the OIM model of osteogenesis
            imperfecta
  JOURNAL   Bone Res 12 (1), 46 (2024)
   PUBMED   39183236
  REMARK    GeneRIF: Schnurri-3 inhibition rescues skeletal fragility and
            vascular skeletal stem cell niche pathology in the OIM model of
            osteogenesis imperfecta.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9021)
  AUTHORS   Li,Z., Shi,B., Li,N., Sun,J., Zeng,X., Huang,R., Bok,S., Chen,X.,
            Han,J., Yallowitz,A.R., Debnath,S., Cung,M., Ling,Z., Zhong,C.Q.,
            Hong,Y., Li,G., Koenen,M., Cohen,P., Su,X., Lu,H., Greenblatt,M.B.
            and Xu,R.
  TITLE     Bone controls browning of white adipose tissue and protects from
            diet-induced obesity through Schnurri-3-regulated SLIT2 secretion
  JOURNAL   Nat Commun 15 (1), 6697 (2024)
   PUBMED   39107299
  REMARK    GeneRIF: Bone controls browning of white adipose tissue and
            protects from diet-induced obesity through Schnurri-3-regulated
            SLIT2 secretion.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9021)
  AUTHORS   Bartolome,R.A., Martin-Regalado,A., Pintado-Berninches,L.,
            Robles,J., Ramirez-Gonzalez,M.A., Boukich,I., Sanchez-Gomez,P.,
            Balyasnikova,I.V. and Casal,J.I.
  TITLE     Schnurri-3 drives tumor growth and invasion in cancer cells
            expressing interleukin-13 receptor alpha 2
  JOURNAL   Cell Death Dis 14 (11), 742 (2023)
   PUBMED   37963919
  REMARK    GeneRIF: Schnurri-3 drives tumor growth and invasion in cancer
            cells expressing interleukin-13 receptor alpha 2.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 9021)
  AUTHORS   Sun,J., Hu,L., Bok,S., Yallowitz,A.R., Cung,M., McCormick,J.,
            Zheng,L.J., Debnath,S., Niu,Y., Tan,A.Y., Lalani,S., Morse,K.W.,
            Shinn,D., Pajak,A., Hammad,M., Suhardi,V.J., Li,Z., Li,N., Wang,L.,
            Zou,W., Mittal,V., Bostrom,M.P.G., Xu,R., Iyer,S. and
            Greenblatt,M.B.
  TITLE     A vertebral skeletal stem cell lineage driving metastasis
  JOURNAL   Nature 621 (7979), 602-609 (2023)
   PUBMED   37704733
REFERENCE   5  (bases 1 to 9021)
  AUTHORS   Stavre,Z., Kim,J.M., Yang,Y.S., Nundel,K., Chaugule,S., Sato,T.,
            Park,K.H., Gao,G., Gravallese,E.M. and Shim,J.H.
  TITLE     Schnurri-3 inhibition suppresses bone and joint damage in models of
            rheumatoid arthritis
  JOURNAL   Proc Natl Acad Sci U S A 120 (19), e2218019120 (2023)
   PUBMED   37141171
  REMARK    GeneRIF: Schnurri-3 inhibition suppresses bone and joint damage in
            models of rheumatoid arthritis.
REFERENCE   6  (bases 1 to 9021)
  AUTHORS   Oukka,M., Kim,S.T., Lugo,G., Sun,J., Wu,L.C. and Glimcher,L.H.
  TITLE     A mammalian homolog of Drosophila schnurri, KRC, regulates TNF
            receptor-driven responses and interacts with TRAF2
  JOURNAL   Mol Cell 9 (1), 121-131 (2002)
   PUBMED   11804591
  REMARK    GeneRIF: KRC overexpression inhibits while antisense or
            dominant-negative KRC enhances NFkappaB-dependent transactivation
            and JNK phosphorylation and consequently, apoptosis and cytokine
            gene expression
REFERENCE   7  (bases 1 to 9021)
  AUTHORS   Hjelmsoe,I., Allen,C.E., Cohn,M.A., Tulchinsky,E.M. and Wu,L.C.
  TITLE     The kappaB and V(D)J recombination signal sequence binding protein
            KRC regulates transcription of the mouse metastasis-associated gene
            S100A4/mts1
  JOURNAL   J Biol Chem 275 (2), 913-920 (2000)
   PUBMED   10625627
REFERENCE   8  (bases 1 to 9021)
  AUTHORS   Mak,C.H., Li,Z., Allen,C.E., Liu,Y. and Wu,L.
  TITLE     KRC transcripts: identification of an unusual alternative splicing
            event
  JOURNAL   Immunogenetics 48 (1), 32-39 (1998)
   PUBMED   9601941
REFERENCE   9  (bases 1 to 9021)
  AUTHORS   Wu,L.C., Liu,Y., Strandtmann,J., Mak,C.H., Lee,B., Li,Z. and
            Yu,C.Y.
  TITLE     The mouse DNA binding protein Rc for the kappa B motif of
            transcription and for the V(D)J recombination signal sequences
            contains composite DNA-protein interaction domains and belongs to a
            new family of large transcriptional proteins
  JOURNAL   Genomics 35 (3), 415-424 (1996)
   PUBMED   8812474
REFERENCE   10 (bases 1 to 9021)
  AUTHORS   Wu,L.C., Mak,C.H., Dear,N., Boehm,T., Foroni,L. and Rabbitts,T.H.
  TITLE     Molecular cloning of a zinc finger protein which binds to the
            heptamer of the signal sequence for V(D)J recombination
  JOURNAL   Nucleic Acids Res 21 (22), 5067-5073 (1993)
   PUBMED   8255760
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL606916.4, AL606930.13 and AL607142.16.
            
            On Jan 25, 2007 this sequence version replaced NM_010657.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY454345.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849387, SAMN01164131
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-113               AL606916.4         116049-116161
            114-192             AL606930.13        110331-110409
            193-389             AL607142.16        29304-29500
            390-5876            AL607142.16        58401-63887
            5877-6019           AL607142.16        68149-68291
            6020-6195           AL607142.16        87309-87484
            6196-6282           AL607142.16        92713-92799
            6283-7190           AL607142.16        96159-97066
            7191-9021           AL607142.16        98018-99848
FEATURES             Location/Qualifiers
     source          1..9021
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 55.51 cM"
     gene            1..9021
                     /gene="Hivep3"
                     /gene_synonym="2900056N03Rik; A130075N07; E030045D18Rik;
                     KBP-1; KBP1; Krc; Rc; Schnurri-3; Shn3; Zas3"
                     /note="human immunodeficiency virus type I enhancer
                     binding protein 3"
                     /db_xref="GeneID:16656"
                     /db_xref="MGI:MGI:106589"
     exon            1..113
                     /gene="Hivep3"
                     /gene_synonym="2900056N03Rik; A130075N07; E030045D18Rik;
                     KBP-1; KBP1; Krc; Rc; Schnurri-3; Shn3; Zas3"
                     /inference="alignment:Splign:2.1.0"
     exon            114..192
                     /gene="Hivep3"
                     /gene_synonym="2900056N03Rik; A130075N07; E030045D18Rik;
                     KBP-1; KBP1; Krc; Rc; Schnurri-3; Shn3; Zas3"
                     /inference="alignment:Splign:2.1.0"
     exon            193..389
                     /gene="Hivep3"
                     /gene_synonym="2900056N03Rik; A130075N07; E030045D18Rik;
                     KBP-1; KBP1; Krc; Rc; Schnurri-3; Shn3; Zas3"
                     /inference="alignment:Splign:2.1.0"
     exon            390..5876
                     /gene="Hivep3"
                     /gene_synonym="2900056N03Rik; A130075N07; E030045D18Rik;
                     KBP-1; KBP1; Krc; Rc; Schnurri-3; Shn3; Zas3"
                     /inference="alignment:Splign:2.1.0"
     CDS             915..7961
                     /gene="Hivep3"
                     /gene_synonym="2900056N03Rik; A130075N07; E030045D18Rik;
                     KBP-1; KBP1; Krc; Rc; Schnurri-3; Shn3; Zas3"
                     /note="recombinant component; kappa-binding protein 1;
                     zinc finger protein ZAS3; KB-binding and regognition
                     component; kappa-B and V(D)J recombination signal
                     sequences-binding protein; human immunodeficiency virus
                     type I enhancer-binding protein 3 homolog; kappa B and Rss
                     recognition component; KB-binding and recognition
                     component"
                     /codon_start=1
                     /product="transcription factor HIVEP3"
                     /protein_id="NP_034787.2"
                     /db_xref="CCDS:CCDS38863.1"
                     /db_xref="GeneID:16656"
                     /db_xref="MGI:MGI:106589"
                     /translation="MDPDQSIKGTKKADGSPRKRLTKGEAIQTSVSSSAPYPGSGTTA
                     PSESATQELLATQPFSGPSQEKTGQQQKPARRPSIEASVHISQLPQHPLTPAFMSPGK
                     PEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASILPPEELPGIPKVFVPR
                     PSQVSLKPAEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPC
                     GFSFKTKSNLYKHRKSHAHRIKAGLASGSSSEMYPPGLEMERIPGEEFEEPTEGESTD
                     SEEETGAASGPSTDVLPKPKHPLLSSSLYSSGSHGSSQERCSLSQSSTGPSLEDPAPF
                     AEASSEHPLSHKPEDTHTIKQKLALRLSERKKLIEEQTFLSPGSKGSTESGYFSRSES
                     AEQQVSPPNTNAKSYAEIIFGKCGRIGQRTSMLASTSTQPLLPLSSEDKPSLVPLSVP
                     RTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLTRRSSVESPKSSLYRDSLSSHGEK
                     TKQEQSLLSLQHPPSSTHPVPLLRSHSMPSAACTISTHHHTFRGSYSFDDHVADPEVP
                     SRNTPVFTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDPTSKPSDEPEPKESDLTKK
                     TKKGFKTKGANYECTICGARYKKRDNYEAHKKYYCSELQITKAHSVGAHEVEKTQAEP
                     EPWSQMMHYKLGATLELTPLRKRRKEKSLGDEEEPPAFGSPGPSETAHNRPLGSTKSP
                     AEASKSAPSLEGPTSFQPRTPKPGAGSEPGKERRTMSKEISVIQHTSSFEKSDPPEQP
                     SGLEEDKPPAQFSSPPPAPHGRSAHSLQPRLVRQPNIQVPEILVTEEPDRPDTEPEPP
                     PKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSP
                     SQESSISLSGSSRSASFDREDHGKAEAPGPFSDTRSKTLGSHMLTVPSHHPHAREMRR
                     SASEQSPNVPHSSHMTETRSKSFDYGSLSPTGPSLAVPAAPPPPAAPPERRKCFLVRQ
                     ASLNRPPEAELEAVPKGKQESSEEPAASKPSTKSSVPQISVGTTQGGPSGGKSQMQDR
                     PPLGSSPPYTEALQVFQPLGTQLPPPASLFSLQQLLPQEQEQSSEFFPTQAMAGLLSS
                     PYSMPPLPPSLFQAPPLPLQPTVLHPSQLHLPQLLPHAADIPFQQPPSFLPMPCPAPS
                     TLSGYFLPLQSQFALQLPGEIESHLPPVKTSLPPLATGPPGPSSSTEYSSDIQLPPVT
                     PQATSPAPTSAPPLALPACPDAMVSLVVPVRIQTHMPSYGSAMYTTLSQILVTQSPGS
                     PASTALTKYEEPSSKSMTVCEADVYEAEPGPSSISKEQNRGYQTPYLRVPERKGTSLS
                     SEGILSLEGCSSTASGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVSTCS
                     VVLTSTEDRKKTEKPHVGGQGRSRREAETLSSLSSDVSDPKELSPLSHSTLSHGTAPG
                     SEALKEYAQPSSKAHRRGLPPMSVKKEDPKEQTDLPPLAPPSSLPLSDTSPKPAKLQE
                     GTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVS
                     TKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSNSRKPRMTEVHLPSLVSPESQKD
                     PARVEKEEKQGKAEEGTPTSKRGEPARVKIFEGGYKSNEEYIYVRGRGRGRYVCEECG
                     IRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETGVLEE
                     LEAEEGTSDDLHQDSEGQEGAEAVEEHQFSDLEDSDSDSDLDEDEEEEEEEEESQDEL
                     SGPCSEAAPPCLPPTLQENSSPVEGPQAPDSTSDEVPQGSSISEATHLTASSCSTPSR
                     GTQGLPRLGLAPLEKDMSSAPSPKATSPRRPWSPSKEAGSRPSLTRKHSLTKNDSSPQ
                     QCSPAREAQASVTSTPGPQMGPGRDLGPHLCGSPRLELSCLTPYPIGREAPAGLERAT
                     DTGTPRYSPTRRWSLGQAESPPQTVLPGKWALAGPCSPSADKSGLGLGPVPRALLQPV
                     PLPHTLLSRSPETCTSAWRKTESRSPSAGPAPLFPRPFSAPHDFHGHLPSRSEENLFS
                     HLPLHSQLLSRAPCPLIPIGGIQMVQARPGAQPTVLPGPCAAWVSGFSGGGSDLTGAR
                     EAQERSRWSPTESPSASVSPVAKVSKFTLSSELEEERTGRGPGRPPDWEPHRAEAPPG
                     PMGTHSPCSPQLPQGHQVAPSWRGLLGSPHTLANLKASSFPPLDRSSSMDCLAETSTY
                     SPPRSRNLSGEPRTRQGSPELLGRGELRTPLFLPKGSGPPSI"
     exon            5877..6019
                     /gene="Hivep3"
                     /gene_synonym="2900056N03Rik; A130075N07; E030045D18Rik;
                     KBP-1; KBP1; Krc; Rc; Schnurri-3; Shn3; Zas3"
                     /inference="alignment:Splign:2.1.0"
     exon            6020..6195
                     /gene="Hivep3"
                     /gene_synonym="2900056N03Rik; A130075N07; E030045D18Rik;
                     KBP-1; KBP1; Krc; Rc; Schnurri-3; Shn3; Zas3"
                     /inference="alignment:Splign:2.1.0"
     exon            6196..6282
                     /gene="Hivep3"
                     /gene_synonym="2900056N03Rik; A130075N07; E030045D18Rik;
                     KBP-1; KBP1; Krc; Rc; Schnurri-3; Shn3; Zas3"
                     /inference="alignment:Splign:2.1.0"
     exon            6283..7190
                     /gene="Hivep3"
                     /gene_synonym="2900056N03Rik; A130075N07; E030045D18Rik;
                     KBP-1; KBP1; Krc; Rc; Schnurri-3; Shn3; Zas3"
                     /inference="alignment:Splign:2.1.0"
     exon            7191..9021
                     /gene="Hivep3"
                     /gene_synonym="2900056N03Rik; A130075N07; E030045D18Rik;
                     KBP-1; KBP1; Krc; Rc; Schnurri-3; Shn3; Zas3"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      8587
                     /gene="Hivep3"
                     /gene_synonym="2900056N03Rik; A130075N07; E030045D18Rik;
                     KBP-1; KBP1; Krc; Rc; Schnurri-3; Shn3; Zas3"
                     /note="major polyA site"
ORIGIN      
        1 gtgtttatga aaaaaaatgc acaatatccc gactgaccgg aataattgaa gaagggtgct
       61 ggatccgtgg gtcagagaac acacaggacc agcttgctac cccaaggctg aaggcctccc
      121 tctgacacag ccttgaagct ttcagaatct ctggcctagc tccaccatga catcacagct
      181 tgctccttat aggatcagag gcacaaacca agctgcctcg aagtagctca tggaagactc
      241 tggagagccg ctggccaggc acgctacccc ttcctcaggg agaagcagtg tgtaagcaga
      301 ggctttgcgg ccggagtgga catgaacgct ggcttccaga gagagcagcg cttcagtttt
      361 ggtcatcgga agtggtgcct gcagcgcaga agaccgtgat ttctcctccg aggctgctat
      421 tctccaatac agaattcaag ggcagaagag ggccgcccca gcatccattg tggcatctct
      481 ccggcccgga ctagggatga caggcccatg gacatggatg tctccgacct tcagctgttc
      541 atatagcaca caggggactc gtgggggccg cttgtcaccc aaacccactc aatggcaata
      601 ctgacatctt ccaggctgtt ttcaagacag gcgttcaggc agaaaaatgc cagtatgctt
      661 tctgtctgca gagtagtggg ctatgccaca ccaatatgaa cagcgtgggc cctgggacct
      721 gctctgagtc cacttgcagc cactgacact tgaggggatt aaaaaaaaaa gcccagcccc
      781 aaaaccatcg tggggttggc ttccatggct cttgaccaat gtggccaaag ctagacacct
      841 cgggacactt ggattattca taaatgcgac ctaccccaaa ctccctgagt agcatctgaa
      901 gtcttgtgaa ggtcatggat cctgaccaaa gcatcaaggg caccaagaag gctgatggaa
      961 gtccccggaa gcggctgacc aaaggagagg ccattcagac gagtgtttct tccagtgctc
     1021 catacccagg cagcggcact actgctccct cagagagtgc cacccaggag ctcctagcca
     1081 cgcagccttt ctcaggcccc tctcaggaga aaacgggcca gcagcagaag cctgcccgga
     1141 ggccttccat cgaggcctcg gtccacatct ctcagcttcc gcagcaccct ctgacaccag
     1201 cattcatgtc cccgggcaag ccagagcatc tcctcgaggg gtccacgtgg cagctggttg
     1261 accccatgag acctggaccc tcgggctcct ttgtggcccc cgggctgcat ccgcagagcc
     1321 agctcctccc atcccatgct tctatccttc ctcctgagga gctgcctggc atccctaagg
     1381 tctttgtgcc tcgtccctca caggtctccc tgaaacctgc agaagaggca cacaagaaag
     1441 agaggaaacc gcagaagcca ggcaagtata tatgtcaata ctgcagccga ccctgcgcca
     1501 agcccagtgt gctccagaaa cacattcgct cacacacagg tgagaggccc tacccctgcg
     1561 gcccctgcgg cttctccttc aagaccaaga gtaacctcta caagcacagg aagtcccatg
     1621 cccaccgtat caaagctggc ctggcctcgg gctccagcag tgagatgtac ccccctgggc
     1681 tggagatgga gaggatcccc ggggaagagt ttgaggaacc caccgaggga gaaagcacag
     1741 actctgagga ggaaacgggt gccgcatcag gtccctccac agatgttctc cccaaaccca
     1801 agcaccccct gctctcaagt agtttgtaca gctccgggag ccacggttcc agccaggaac
     1861 gctgctccct ctcccagtca agcactggcc catcactaga ggaccccgcc ccatttgcag
     1921 aagcctcatc ggaacatccc ctgagccata aaccggaaga cacgcacacc atcaagcaga
     1981 agctggcact ccgcctgagt gagaggaaga agctgatcga agagcagaca ttcctgagcc
     2041 cagggagcaa aggcagcaca gagtccgggt acttctcacg ctctgagagc gctgagcagc
     2101 aggtcagccc ccccaacacc aacgcaaagt cctacgcaga gatcatcttc ggcaagtgtg
     2161 gacggattgg gcagcggacc tccatgctgg catccacctc tacccagccc ctactgcctc
     2221 tatcctcgga agacaagccc agcttggtac ctttgtctgt gcccaggaca caagtgatcg
     2281 aacatatcac caagctcatc accatcaatg aagccgtggt ggacaccagt gagatcgaca
     2341 gtgtgaagcc caggaggagc tctctaacca ggcgcagcag cgtggagtcc ccgaagtcca
     2401 gcctctaccg ggactcacta tcgtcccatg gggagaagac taagcaggag caatcactgc
     2461 tgagcctcca gcacccaccc agctccacgc accctgtgcc tctcctgaga agtcactcaa
     2521 tgccttctgc cgcctgcacc atcagcaccc accaccacac cttccgtggt agctactcct
     2581 ttgatgacca cgtcgctgac cccgaggtcc ccagccgcaa cactcccgtg tttacctccc
     2641 acccacggat gctaaagcgc cagccagcca ttgaattacc tttggggggt gagtacagtt
     2701 ccgaggagcc tggaccgagc agcaaggacc ccacctccaa gccctccgat gaaccagaac
     2761 ccaaggaaag cgaccttacc aaaaagacca agaaggggtt caaaacaaaa ggcgcgaact
     2821 atgaatgtac catctgcggt gctcggtaca aaaagagaga taattacgaa gctcataaga
     2881 agtactactg ctctgagctc cagatcacaa aagcccactc tgtaggtgct catgaagtgg
     2941 aaaagactca ggctgagcct gagccttggt cccagatgat gcattataaa ctgggggcca
     3001 ccttggaact cactccgctg agaaaaagac ggaaagaaaa gagccttgga gatgaggaag
     3061 agccacctgc ctttggcagc ccaggccctt cagaaacagc tcataaccgt cccctggggt
     3121 ccaccaagtc accagcagaa gcaagcaaat cagcgccctc tctagaggga cccacgagct
     3181 tccagcccag gactcccaag ccaggagctg ggtcagaacc agggaaggag aggagaacaa
     3241 tgtccaaaga aatttccgtc atccagcaca ccagctcctt tgagaagtct gacccaccgg
     3301 agcagcccag tggcctggag gaagacaagc ccccggccca gttctcatcc ccaccacctg
     3361 ccccgcacgg acgctccgct cactccctgc agccaaggtt ggtccggcag cccaacattc
     3421 aggttccaga gatcctcgtg acagaagaac cggacaggcc tgacacagag cctgagccgc
     3481 cccccaagga gcctgagaag acagaagaat tccagtggcc ccagcgcagc cagacactgg
     3541 cacaactccc agcggagaag ctgccaccca agaaaaagag actccgcctg gctgagatgg
     3601 cgcagtcctc gggggagtcc agctttgagt cctccgtgcc tctgtctcga agcccaagcc
     3661 aggagagcag catttctctg agtggctcca gccgctcggc ttcattcgac agggaagacc
     3721 atggaaaagc tgaggcccct ggacccttct cagacacacg ctccaaaacc ttgggctccc
     3781 acatgctgac tgtccccagc caccacccac atgcccgaga gatgagacgg tcagcctcag
     3841 agcagagccc caatgtgccc cattcctcac acatgactga gacccgaagc aaatcctttg
     3901 actacggcag cttgtcccct acaggaccat ccttagcagt gcctgctgct ccgccacccc
     3961 cagccgcccc gccagaaaga agaaaatgct ttctggtacg tcaggcctcc ctgaacagac
     4021 ctccagaagc cgagctggag gctgtgccca agggaaaaca agagagcagt gaggagcccg
     4081 cagccagcaa gccttccaca aaaagctctg tgccccagat ctctgtgggc actacgcaag
     4141 gtgggccttc agggggcaaa agccagatgc aggacaggcc cccactggga tccagcccac
     4201 cctacacaga agctctgcaa gtgttccaac ctctcggcac ccagctgccc cctccagcct
     4261 ctctcttctc cttgcaacag ctcttgcctc aggagcaaga acaatcctct gagttcttcc
     4321 ccacacaagc aatggccggc ctcctctcct ccccatactc catgcccccg ctcccacctt
     4381 ccttgttcca agccccacca cttcctctac agcctactgt gctacacccc agccagctcc
     4441 atctccccca gctcctgcct cacgctgcag atatcccctt ccagcagccc ccttcctttc
     4501 tccccatgcc atgccctgcc ccttcaaccc tctccggata tttcctccct ctgcaatccc
     4561 agtttgcact gcagctccct ggtgaaatag aaagccactt gcccccagtc aaaaccagcc
     4621 tgccccctct ggccacagga cctcctggcc cctccagcag cacagaatac agcagtgaca
     4681 tccagctgcc tcctgtgact ccccaagcca cctccccagc tcccacatca gccccaccac
     4741 tggcccttcc tgcctgtcca gatgccatgg tgtcactggt tgttcctgtc cgaatccaga
     4801 cccatatgcc atcctatgga agtgccatgt acaccacttt gtctcagatc ttggtcacac
     4861 agtctccggg tagcccagca agcacggccc ttaccaagta cgaggaaccc tcctccaaaa
     4921 gtatgactgt ttgtgaggct gatgtatatg aggctgagcc tgggccatcg agcataagca
     4981 aggaacaaaa cagaggttac cagacaccat atctgagagt acctgaaagg aaaggcactt
     5041 cactgtcttc tgagggtatc ctgagcctgg aggggtgctc atccacagcc agtggaagca
     5101 agcgcgtcct ttccccagct ggcagtcttg aacttaccat ggaaacccag cagcagaaaa
     5161 gggtaaagga ggaagaagct tccaaggcag atgaaaaact ggagcttgtg agtacctgta
     5221 gtgtcgtgct gacaagtaca gaggatagga agaagacaga gaaaccccat gtgggtggcc
     5281 agggccggag caggagggag gcagaaacac tgtccagctt gtcttcagat gtatccgacc
     5341 caaaagaact ttctcccctc tctcattcca cattgtccca tgggacagcc ccaggctcag
     5401 aagctttgaa ggaatatgcc caaccatcta gcaaagctca ccgaagaggt ctgcctccaa
     5461 tgagtgtaaa gaaagaagat ccaaaggaac agactgacct ccctcccctg gcacccccta
     5521 gttctctgcc tctgtcagat acttccccta aaccagccaa attgcaagaa ggtacggact
     5581 caaagaaggt actgcagttc cccagcctcc acacaaccac taatgtcagt tggtgctatt
     5641 taaactacat taagccaaat cacatccagc atgcagatag gaggtcctct gtttacgctg
     5701 gttggtgcat aagtttgtac aaccccaacc ttccaggggt ttccactaaa gctgctttgt
     5761 ccctcctgcg atctaagcag aaggtgagca aagagacata taccatggcc acagctccgc
     5821 atcctgaggc aggaaggctg gttccatcca actcccgaaa gccccgcatg acagaggtgc
     5881 acctcccgtc gctggtttcc ccagagagcc agaaagaccc agctagagtg gaaaaggaag
     5941 aaaagcaagg gaaggcggag gaaggtactc ccacttccaa gagaggcgag ccggcgaggg
     6001 tcaagatctt cgaaggaggg tacaaatcaa acgaagagta tatatatgtg cgaggccgcg
     6061 gccgagggag atatgtttgt gaggaatgtg gaattcgctg caagaagccc agcatgctga
     6121 agaaacacat ccgcacccac actgacgtcc ggccctatgt gtgcaagcac tgtcactttg
     6181 cttttaaaac caaagggaat ctgactaagc acatgaagtc gaaagcccac agcaaaaagt
     6241 gccaagagac gggggtgctg gaggagctgg aagccgaaga aggaaccagt gatgacctgc
     6301 accaggactc agaggggcaa gagggcgccg aggctgtgga ggagcaccag ttctcagacc
     6361 tggaggactc tgactcagac tcagacctgg atgaagatga ggaggaggaa gaggaggagg
     6421 aagagagcca ggatgagctg tctgggccat gctcggaggc agctccgcct tgcctgcccc
     6481 ccacactaca ggagaactcc tcacccgttg agggccctca ggctccagat agcacttctg
     6541 acgaggtccc gcaaggcagc tccatctcag aagccacgca tttgaccgcc agcagttgtt
     6601 ccacacctag ccggggtacc caaggccttc ccaggctggg actggcccca ctggagaagg
     6661 acatgagctc agccccgagt cccaaggcca cgtcccctag gaggccgtgg tccccaagca
     6721 aagaagcagg cagccgcccc tcactcactc gcaaacattc actcaccaaa aatgactcgt
     6781 ctccccagca atgttcaccg gcccgagaag ctcaggcctc agtaacgagc acacctggtc
     6841 cccagatggg cccaggaagg gacctgggcc ctcacctttg tgggtctcca agactggagc
     6901 tgtcctgtct cactccctac cccataggaa gagaagcgcc cgctggactc gagcgtgcca
     6961 cagacacagg cacccccaga tattcaccca ccaggagatg gtctctgggt caggccgagt
     7021 caccgccaca gacagtgctg ccagggaaat gggccctggc tgggccctgc agcccctcag
     7081 cggacaagag tggcctgggc ttggggccgg ttccacgggc cctcctccag cccgtgcctc
     7141 tacctcacac acttctcagc agaagccctg aaacgtgcac ctctgcatgg cggaagactg
     7201 agtcccgaag tccatcagct ggccctgctc ctctcttccc ccgaccattc tccgcccctc
     7261 atgacttcca tggccacctc cctagccgaa gtgaggagaa cctcttcagc cacctgcctc
     7321 tgcattccca gctcctgagc cgcgccccct gccccctcat tcccatcggt gggatccaga
     7381 tggtacaggc ccggccagga gcccagccca ccgtgcttcc tggaccctgc gcggcctggg
     7441 tcagtggctt ctcagggggc ggcagtgacc taactggggc ccgagaggcc caggagcgca
     7501 gccgctggag tcccacagag agcccttcag catcggtgtc ccctgtggcc aaggtctcca
     7561 agtttacact ctcgtcagag ctggaagagg aaaggaccgg cagaggccca ggaagacctc
     7621 ctgactggga acctcacagg gctgaagccc ctccaggacc catgggcaca cacagcccct
     7681 gctccccaca gctgccccaa ggccaccagg tggcaccttc ctggaggggc ctcttggggt
     7741 caccacacac actggccaac ctaaaggcct caagcttccc accactggat cgcagcagct
     7801 ccatggactg cctggcagag acctccactt actctccacc ccggagcagg aacctctctg
     7861 gagaacccag gacccgtcaa ggctcccctg agctcttagg tagaggggag ctcaggacac
     7921 ctctattcct gcccaagggt agtggccccc caagcatcta gcctctacag ctacttcagc
     7981 gcctggcctc cagtgtcggc agcagacatg cccagacaac cgcctggagt catcttgctc
     8041 ccttgggcat cctctcccat ctgtccatct gtccatctat ccatgcagct tctgctcagc
     8101 cccatctgtt ctatttctcc acatatgcag ttacctgtgc ctttttctag accttttgtt
     8161 gcttgagaaa aaaaaaaaga aacaaaacaa atcacacaca tccataaaca aaacaaaaca
     8221 aaacaaaacg catccctgag gagctgaagg ctgtgagtgt gctctgggga caaggctgga
     8281 ggagggaatc tcacctccac caccaccatg tgccacatgg gcagctgtcc ccacctcaag
     8341 gtccaggaga gggtctgtgg cactgagaga gaagaagaaa aggggagaaa aactgtaatt
     8401 aaattcaaag gcaagcactc ctacagtcag atgcccacca tccccactga aagacgcaca
     8461 gctcgtagcc gcccttctct gccatcagag ggacacaaat acaggcagga accaatctac
     8521 cactccccac cctacccgac caaggacatt atcttttatc cttttttttt ttttcaagag
     8581 taggaaccaa aaagaaaaac tactttctag catctcagca gcacagacta gcagcaggaa
     8641 agagaagaat tctgtagtat gaactgtggc tctcacttct cccttccaca ccccacctcc
     8701 cctcccctca ccccacccca tcccccaggc tcataaagga gcccgggttg cccatctcct
     8761 ttctcctata cactataggt ctctgcctcc caggcctggc caaaggctgg ctcctctatg
     8821 attagaaata cctgcaggat gaagggacca aggccggact agggatggtc ctagtctggg
     8881 cctgttttga gcctggggtt tggattggtt cacctctgtc cctgaggaac aacatgtcac
     8941 atttccttca tggctggatt aacgtatgtg tgtgtgtata tagatacaca gagagaaacc
     9001 aaagatggtg tttggtactt t
//
