LOCUS       NM_030175               2769 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus hedgehog interacting protein-like 2 (Hhipl2),
            transcript variant 1, mRNA.
ACCESSION   NM_030175
VERSION     NM_030175.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2769)
  AUTHORS   Katoh,Y. and Katoh,M.
  TITLE     Comparative genomics on HHIP family orthologs
  JOURNAL   Int J Mol Med 17 (2), 391-395 (2006)
   PUBMED   16391842
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AEKQ02108034.1, AK019671.1 and AW909171.1.
            
            On Apr 21, 2015 this sequence version replaced NM_030175.4.
            
            Transcript Variant: This variant (1) represents the longer
            transcript and encodes the longer isoform (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11927937.4217010.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849383, SAMN00849384
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-360               AEKQ02108034.1     49397-49756         c
            361-2520            AK019671.1         148-2307
            2521-2769           AW909171.1         1-249               c
FEATURES             Location/Qualifiers
     source          1..2769
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1"
     gene            1..2769
                     /gene="Hhipl2"
                     /gene_synonym="4930507C10Rik; Hhip3"
                     /note="hedgehog interacting protein-like 2"
                     /db_xref="GeneID:78772"
                     /db_xref="MGI:MGI:1926022"
     exon            1..360
                     /gene="Hhipl2"
                     /gene_synonym="4930507C10Rik; Hhip3"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..2196
                     /gene="Hhipl2"
                     /gene_synonym="4930507C10Rik; Hhip3"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; HHIP-like protein 2"
                     /codon_start=1
                     /product="HHIP-like protein 2 isoform 1 precursor"
                     /protein_id="NP_084451.2"
                     /db_xref="CCDS:CCDS56664.1"
                     /db_xref="GeneID:78772"
                     /db_xref="MGI:MGI:1926022"
                     /translation="MLGKHTSPHTVPGHRAPWLSPGIFCLGLPFLLGWVGLLQGHPQC
                     LDYGPPFRPPQHLDFCSDYDSFGCCDQRKDRRIAARYWDIMSYFDLKAHELCGGYIKD
                     ILCQECSPYAAHLYDAENPQTPLRNLPGLCSDYCSAFHRSCHSAISLLTNDRGLQESH
                     GKDGARFCHLLNLPDEDYCFPNVLRNDQLNRNLGVVAEDQQGCLQLCLVEVANGLRNP
                     VSMVHAGDGTHRFFVAEQVGVVWVYLPDGSRLEQPFLDLKSMVLTTPWIGDERGFLGL
                     AFHPKFRHNRKFYIYYSCLGKRKVEKIRISEMKVSLSDGNRADPKSERVILEIDEPAS
                     NHNGGQLLFGLDGYLYIFTGDGGQAGDPFGKFGNAQNKSSLLGKVLRIDVNGADVDGQ
                     RYRVPLDNPFVSEPGAHPAVYAYGVRNMWRCAVDRGDPVTHRGRGRIFCGDVGQNKFE
                     EVDLIVKGGNYGWRAKEGFECYDKRLCRNASLDDILPIYAYGHGVGKSVTGGYVYRGC
                     ESPNLNGLYIFGDFMSGRLMALQEDRKTQKWTKRDICLGNSTCAFPGLISAYSRFIIS
                     FAEDEAGELYFLATSYPSAYAPHGSIYKFVDPSRRAPPGKCKYKPVPVKTKSKKVRFR
                     PLAATVLDLLKEESQKAARKASNATFTSSSDRVASQKGSLKKPASSRSSKKTFRRPGT
                     KKKSRVWSPRPQGKRKPNLDSHGVGMRQAAGRSHP"
     exon            361..1013
                     /gene="Hhipl2"
                     /gene_synonym="4930507C10Rik; Hhip3"
                     /inference="alignment:Splign:2.1.0"
     exon            1014..1157
                     /gene="Hhipl2"
                     /gene_synonym="4930507C10Rik; Hhip3"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1489
                     /gene="Hhipl2"
                     /gene_synonym="4930507C10Rik; Hhip3"
                     /inference="alignment:Splign:2.1.0"
     exon            1490..1616
                     /gene="Hhipl2"
                     /gene_synonym="4930507C10Rik; Hhip3"
                     /inference="alignment:Splign:2.1.0"
     exon            1617..1759
                     /gene="Hhipl2"
                     /gene_synonym="4930507C10Rik; Hhip3"
                     /inference="alignment:Splign:2.1.0"
     exon            1760..1841
                     /gene="Hhipl2"
                     /gene_synonym="4930507C10Rik; Hhip3"
                     /inference="alignment:Splign:2.1.0"
     exon            1842..1924
                     /gene="Hhipl2"
                     /gene_synonym="4930507C10Rik; Hhip3"
                     /inference="alignment:Splign:2.1.0"
     exon            1925..2769
                     /gene="Hhipl2"
                     /gene_synonym="4930507C10Rik; Hhip3"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2498..2503
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hhipl2"
                     /gene_synonym="4930507C10Rik; Hhip3"
                     /note="hexamer: AATAAA"
     polyA_site      2523
                     /gene="Hhipl2"
                     /gene_synonym="4930507C10Rik; Hhip3"
                     /note="major polyA site"
     regulatory      2749..2754
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hhipl2"
                     /gene_synonym="4930507C10Rik; Hhip3"
                     /note="hexamer: AATAAA"
     polyA_site      2769
                     /gene="Hhipl2"
                     /gene_synonym="4930507C10Rik; Hhip3"
                     /note="major polyA site"
ORIGIN      
        1 ggccaaccca ggaaggagca gcagagaatt cccaaggtcc aaatgctggg aaaacatact
       61 agcccacaca ctgttcctgg tcatcgggcc ccgtggctct ctcctggcat tttctgcctg
      121 ggcctcccgt tcttgttggg ctgggtgggc ctgctgcagg gacaccccca gtgcttggat
      181 tatggaccac ccttccgtcc tcctcagcac ctggactttt gctctgacta tgactccttc
      241 ggctgctgtg atcagcgcaa agaccgccgc atcgctgcca ggtactggga catcatgagc
      301 tactttgacc tgaaggccca cgagctgtgt ggaggttaca ttaaagacat cctttgccag
      361 gagtgttctc cctacgcggc tcacctctac gatgccgaga acccccagac accgctccgg
      421 aaccttccgg gcctctgctc tgactactgc tctgccttcc accgcagctg ccactcggcc
      481 atctccttgc taaccaatga ccgtggcctc caggagtccc atggcaaaga tggtgctcgc
      541 ttctgtcacc tcctcaacct tcctgacgag gactactgct tccccaatgt cctgaggaac
      601 gatcaactca accgcaacct gggagtggtg gctgaggacc agcagggctg cctgcagctc
      661 tgcctggtcg aggtggccaa tggcttgagg aaccctgtgt ccatggtcca cgctggggat
      721 ggcacccacc gcttctttgt cgctgagcag gtaggagtgg tgtgggtcta cctccctgat
      781 gggagccgcc tggaacagcc cttcctggat ctcaagagca tggtgctgac cacaccgtgg
      841 atcggggatg agagaggctt cttgggtctc gcttttcacc ccaaattccg ccacaaccgc
      901 aagttctaca tttattattc atgcctgggc aagaggaagg tggagaaaat ccggattagt
      961 gagatgaagg tttccctgtc tgacggcaac agagcagatc ccaaatcaga gagggtcatc
     1021 ttggagatag acgaaccagc ctccaaccac aatggtggac agcttctctt tggcctggat
     1081 ggttatctgt acatattcac tggggacgga gggcaggctg gggatccctt tggcaagttc
     1141 ggaaatgctc agaacaaaag ttctctgctg gggaaagtgt taaggattga tgtgaatggg
     1201 gcagacgtgg atggccagcg gtaccgagtg cccctggaca atccgtttgt ctctgagcca
     1261 ggtgcccacc ctgccgtcta tgcttacggg gtcagaaaca tgtggcgctg tgctgtggac
     1321 cgaggagacc ccgtcacaca ccggggccga ggtcggatat tctgtgggga cgtgggccag
     1381 aacaagttcg aggaagtcga ccttatagtt aaaggcggga actatggctg gagagccaag
     1441 gaagggtttg aatgttatga caagagactt tgccgtaatg cgtccttgga tgacattctg
     1501 cccatctatg cttatggcca tggggtagga aagtcagtca ctggagggta tgtctaccgt
     1561 gggtgtgaat cccccaatct caatggactc tacatctttg gggacttcat gagtggtcga
     1621 cttatggctt tgcaggaaga taggaaaacc cagaaatgga caaagcgaga catctgcttg
     1681 ggcaactcga cctgcgcctt cccggggctg atcagtgcat acagcaggtt catcatctcc
     1741 tttgctgaag atgaagcagg agagctgtat ttcctggcca cctcctaccc aagtgcctat
     1801 gcgccacatg gatctattta caagtttgtc gatccttcaa ggcgagcccc accaggcaag
     1861 tgcaaataca agccagtgcc cgtgaaaacc aagagtaaga aggtccggtt ccggccactc
     1921 gccgccacag tcttggactt gctgaaggag gaatcgcaga aagcagcccg aaaagcatcc
     1981 aacgcaacct tcacttctag ctcagacagg gttgcatctc agaagggctc cctcaagaag
     2041 ccagcttctt cccgaagcag caagaaaaca tttcgaaggc ctggtaccaa gaagaaaagc
     2101 agagtgtggt ccccacgtcc ccagggcaag aggaagccca atcttgacag ccatggtgta
     2161 gggatgagac aggccgcagg cagaagtcac ccatgacctc ttggtcatct tggccgatga
     2221 gacctgagac aggagaatgc ttcactgagt gcataatgct gtccattctg agtctgggac
     2281 tcagacagtc aagaagcctg ggtggcggtg ggctgttttc tgtgtggtct tttccctccc
     2341 tgggaaatct tgctgtctac tgaagaaaca tgagcctggt ctgcgggcag catttctgtg
     2401 gagataccac agcccacagg accttgcacg tggcttatgg catgtccagt gtgcatacct
     2461 gcctggcatc ccacctgaca tcctttctac ctggggtaat aaattacctt tggcttacac
     2521 gtacacatcc tttgatctca gtgtttggca atggggaatc tagcatgttt cagccagctt
     2581 gctttagcag ctcgctcctc tctgctgctg cctgtgactg gctcctatgt aagccctctg
     2641 gaagatagat ggcccctttc tttcctccag acagaagcct gtgaactgaa gacaaggagg
     2701 cttgcctctg atcctccagc agttgttatt tgggttcagc taatggccaa taaacacaac
     2761 tgcattcca
//
