LOCUS       NM_020259               9094 bp    mRNA    linear   ROD 21-AUG-2024
DEFINITION  Mus musculus Hedgehog-interacting protein (Hhip), transcript
            variant 1, mRNA.
ACCESSION   NM_020259
VERSION     NM_020259.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 9094)
  AUTHORS   Yoshida,S., Tsuneoka,Y., Tsukada,T., Nakakura,T., Kawamura,A.,
            Kai,W. and Yoshida,K.
  TITLE     Primary Cilia are Required for Cell-Type Determination and
            Angiogenesis in Pituitary Development
  JOURNAL   Endocrinology 165 (8) (2024)
   PUBMED   39001875
REFERENCE   2  (bases 1 to 9094)
  AUTHORS   Kumari,A., Franks,N.E., Li,L., Audu,G., Liskowicz,S., Johnson,J.D.,
            Mistretta,C.M. and Allen,B.L.
  TITLE     Distinct expression patterns of Hedgehog signaling components in
            mouse gustatory system during postnatal tongue development and
            adult homeostasis
  JOURNAL   PLoS One 19 (6), e0294835 (2024)
   PUBMED   38848388
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 9094)
  AUTHORS   Leung,A.O.W., Poon,A.C.H., Wang,X., Feng,C., Chen,P., Zheng,Z.,
            To,M.K., Chan,W.C.W., Cheung,M. and Chan,D.
  TITLE     Suppression of apoptosis impairs phalangeal joint formation in the
            pathogenesis of brachydactyly type A1
  JOURNAL   Nat Commun 15 (1), 2229 (2024)
   PUBMED   38472182
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 9094)
  AUTHORS   Wang,X., Zhang,Y., Yu,J., Ma,Y., Xu,Y., Shi,J., Qi,Z. and Liu,X.
  TITLE     Identification and analysis of key circRNAs in the mouse embryonic
            ovary provides insight into primordial follicle development
  JOURNAL   BMC Genomics 25 (1), 139 (2024)
   PUBMED   38310234
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 9094)
  AUTHORS   Zanini,F., Che,X., Suresh,N.E., Knutsen,C., Klavina,P., Xie,Y.,
            Domingo-Gonzalez,R., Liu,M., Kum,A., Jones,R.C., Quake,S.R.,
            Alvira,C.M. and Cornfield,D.N.
  TITLE     Hyperoxia prevents the dynamic neonatal increases in lung
            mesenchymal cell diversity
  JOURNAL   Sci Rep 14 (1), 2033 (2024)
   PUBMED   38263350
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 9094)
  AUTHORS   Chuang,P.T., Kawcak,T. and McMahon,A.P.
  TITLE     Feedback control of mammalian Hedgehog signaling by the
            Hedgehog-binding protein, Hip1, modulates Fgf signaling during
            branching morphogenesis of the lung
  JOURNAL   Genes Dev 17 (3), 342-347 (2003)
   PUBMED   12569124
REFERENCE   7  (bases 1 to 9094)
  AUTHORS   Kawakami,T., Kawcak,T., Li,Y.J., Zhang,W., Hu,Y. and Chuang,P.T.
  TITLE     Mouse dispatched mutants fail to distribute hedgehog proteins and
            are defective in hedgehog signaling
  JOURNAL   Development 129 (24), 5753-5765 (2002)
   PUBMED   12421714
REFERENCE   8  (bases 1 to 9094)
  AUTHORS   Gritli-Linde,A., Bei,M., Maas,R., Zhang,X.M., Linde,A. and
            McMahon,A.P.
  TITLE     Shh signaling within the dental epithelium is necessary for cell
            proliferation, growth and polarization
  JOURNAL   Development 129 (23), 5323-5337 (2002)
   PUBMED   12403705
REFERENCE   9  (bases 1 to 9094)
  AUTHORS   Outram,S.V., Varas,A., Pepicelli,C.V. and Crompton,T.
  TITLE     Hedgehog signaling regulates differentiation from double-negative
            to double-positive thymocyte
  JOURNAL   Immunity 13 (2), 187-197 (2000)
   PUBMED   10981962
  REMARK    Erratum:[Immunity 2000 Oct;13(4):585]
REFERENCE   10 (bases 1 to 9094)
  AUTHORS   Chuang,P.T. and McMahon,A.P.
  TITLE     Vertebrate Hedgehog signalling modulated by induction of a
            Hedgehog-binding protein
  JOURNAL   Nature 397 (6720), 617-621 (1999)
   PUBMED   10050855
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY142826.1, BC053012.1, AK031841.1, CV561558.1, AC109146.26 and
            AW121326.1.
            
            On Nov 16, 2007 this sequence version replaced NM_020259.3.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data because no single transcript was available
            for the full length of the gene. The extent of this transcript is
            supported by transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK031539.1, BC053012.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                BY142826.1         2-16
            16-1910             BC053012.1         1-1895
            1911-1911           AK031841.1         1421-1421
            1912-3055           BC053012.1         1897-3040
            3056-3312           CV561558.1         336-592
            3313-8585           AC109146.26        120757-126029       c
            8586-9094           AW121326.1         1-509               c
FEATURES             Location/Qualifiers
     source          1..9094
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 37.95 cM"
     gene            1..9094
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /note="Hedgehog-interacting protein"
                     /db_xref="GeneID:15245"
                     /db_xref="MGI:MGI:1341847"
     exon            1..772
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /inference="alignment:Splign:2.1.0"
     CDS             494..2596
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1"
                     /codon_start=1
                     /product="hedgehog-interacting protein isoform 1
                     precursor"
                     /protein_id="NP_064655.4"
                     /db_xref="CCDS:CCDS22440.1"
                     /db_xref="GeneID:15245"
                     /db_xref="MGI:MGI:1341847"
                     /translation="MLKMLSFKLLLLAVALGFFEGDAKFGERNEGSGARRRRCLNGNP
                     PKRLKRRDRRVMSQLELLSGGEILCGGFYPRVSCCLQSDSPGLGRLENKIFSATNNSE
                     CSRLLEEIQCAPCSPHSQSLFYTPERDVLDGDLALPLLCKDYCKEFFYTCRGHIPGLL
                     QTTADEFCFYYARKDAGLCFPDFPRKQVRGPASNYLGQMEDYEKVGGISRKHKHNCLC
                     VQEVMSGLRQPVSAVHSGDGSHRLFILEKEGYVKILTPEGELFKEPYLDIHKLVQSGI
                     KGGDERGLLSLAFHPNYKKNGKLYVSYTTNQERWAIGPHDHILRVVEYTVSRKNPHQV
                     DVRTARVFLEVAELHRKHLGGQLLFGPDGFLYIILGDGMITLDDMEEMDGLSDFTGSV
                     LRLDVDTDMCNVPYSIPRSNPHFNSTNQPPEVFAHGLHDPGRCAVDRHPTDININLTI
                     LCSDSNGKNRSSARILQIIKGRDYESEPSLLEFKPFSNGPLVGGFVYRGCQSERLYGS
                     YVFGDRNGNFLTLQQSPVTKQWQEKPLCLGASSSCRGYFSGHILGFGEDELGEVYILS
                     SSKSMTQTHNGKLYKIVDPKRPLMPEECRVTVQPAQPLTSDCSRLCRNGYYTPTGKCC
                     CSPGWEGDFCRIAKCEPACRHGGVCVRPNKCLCKKGYLGPQCEQVDRNVRRVTRAGIL
                     DQIIDMTSYLLDLTSYIV"
     exon            773..965
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1122
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1123..1324
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1325..1476
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1477..1650
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1651..1794
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1795..1916
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1917..2040
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2041..2171
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2172..2253
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2254..2402
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /inference="alignment:Splign:2.1.0"
     exon            2403..9078
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      9055..9060
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /note="hexamer: ATTAAA"
     polyA_site      9078
                     /gene="Hhip"
                     /gene_synonym="Hhip1"
                     /note="major polyA site"
ORIGIN      
        1 atgagaggct gtgtgagaag ctgcagccgc cggcagagga gacctcagca tcctcgggag
       61 cccagcgcca accctgcctc cgcccggccc gctgccacca ccgccgccct ttcggttcct
      121 gctactgtct cacctaaaca actcccattc agcggacaag cgaagttcta tgactctctt
      181 ctcctctcct tcctcctctt cttccaactc cttctcctcc cacttcccaa ccgctgtgga
      241 aagcccctaa cccaacagac gctggcaagg ctgcggacaa gtgtcatctg cactttatct
      301 tgctgctcct actgccctaa ggcaaagttg catagctcta catctttctt tcccagccac
      361 ctccctctgc ccccaagagc gtcccgccgc cccgcagcac tctcctggag ctgcgcccta
      421 gtgcccctgc tgggcagtgg cctttccccc accccatcct cccgcgtcct gcccttgctg
      481 ctccgggcag acgatgctga agatgctctc gtttaagctg ctactgctgg ccgtggctct
      541 gggcttcttt gaaggagatg cgaagtttgg ggaaaggaac gaggggagcg gagcgagaag
      601 gagacggtgc ctgaatggga accccccaaa gcgcctaaag agaagggaca ggcgggtgat
      661 gtcccagctg gagctgctca gtggaggaga gatcctgtgt ggtggcttct acccacgagt
      721 atcttgctgc ctgcagagtg acagccctgg attggggcgt ctggagaaca agatcttttc
      781 tgccaccaac aactcagaat gcagcaggct gctggaggag atccaatgtg ctccctgctc
      841 cccgcattcc cagagcctct tctacacacc tgaaagagat gtcctggatg gggacctagc
      901 acttccactc ctctgcaaag actactgcaa agaattcttt tatacttgcc gaggccatat
      961 tccaggtctt cttcaaacaa ctgctgatga attttgcttt tactatgcaa gaaaagatgc
     1021 tgggttatgc tttccagact tcccgagaaa gcaagtcaga ggaccagcat ctaactactt
     1081 gggccagatg gaagactacg agaaagtggg ggggatcagc agaaaacaca aacacaactg
     1141 cctctgtgtc caggaggtca tgagtgggct gcggcagcct gtgagcgctg tgcacagcgg
     1201 ggatggctcc catcggctct tcattctaga gaaggaaggc tacgtgaaga ttctaacccc
     1261 agaaggagaa ctgttcaagg agccttactt ggacattcac aaacttgttc aaagtggaat
     1321 aaagggagga gacgaaaggg gcctgctaag cctggcattc catcccaatt acaagaaaaa
     1381 tggaaagctg tatgtgtctt ataccaccaa ccaggaacgg tgggctattg ggcctcacga
     1441 ccacattctt cgggttgtgg aatacacagt atccaggaaa aacccccatc aagttgatgt
     1501 gagaacagcc agggtgtttc tggaagtcgc agagctccac cgaaagcatc ttgggggaca
     1561 gctgctcttt ggtcctgatg gctttttgta catcatcctt ggggatggta tgatcacatt
     1621 ggatgacatg gaagagatgg atgggttaag tgacttcaca ggctctgtgc tgaggctgga
     1681 cgtggacacc gacatgtgca atgtgcctta ttccatacct cggagtaacc ctcacttcaa
     1741 cagcaccaac cagcccccag aagtatttgc ccacggcctc catgatccag gcagatgtgc
     1801 cgtggatcga catcctactg atataaacat caatttaaca atactttgct cagattccaa
     1861 cgggaaaaac aggtcatcag ccagaatcct acagataata aagggaagag attatgaaag
     1921 tgagccatct cttcttgaat tcaagccatt cagtaacggc cctttggttg gtggatttgt
     1981 ttacagaggc tgtcagtctg aaagattgta cggaagctat gtgttcggag atcgcaatgg
     2041 gaatttctta accctccagc aaagcccagt gaccaagcaa tggcaagaaa agccgctctg
     2101 cctgggtgcc agcagctcct gtcgaggcta cttttcgggt cacatcttgg gatttggaga
     2161 agatgaatta ggagaggttt acattctatc aagcagtaag agtatgaccc agactcacaa
     2221 tggaaaactc tacaagatcg tagaccccaa aagaccttta atgcctgagg aatgcagagt
     2281 cacagttcaa cctgcccagc cactgacctc cgattgctcc cggctctgtc gaaacggcta
     2341 ctacaccccc actggcaagt gctgctgcag tcccggctgg gagggagact tctgcagaat
     2401 tgccaagtgt gagccagcgt gccgtcatgg aggtgtctgt gtcagaccga acaagtgcct
     2461 ctgtaaaaag ggctatcttg gtcctcaatg tgaacaagtg gacaggaacg tccgcagagt
     2521 gaccagggca ggtatccttg atcagatcat tgacatgacg tcttacttgc tggatctcac
     2581 aagttacatt gtatagtttc tgggacagtt cgagtctatc tttccagtgg gcatttattt
     2641 tgaccttgtc atcattaaaa agagagactg tccttctgct acacacctct gtgatttcat
     2701 tcttctttta gtaatttaaa agcaattatc agaaatgtac agctctcagc atgtatgttg
     2761 gcacatttct tcacatctgc atacacacgc acaaccccaa actcgaggtt gtataacaga
     2821 aggatttttt tgttgtgttt tgttttgttt ttaatatcta cttgctggta tggagtactt
     2881 tacacagaag ttccactgca aattcgtcac agagtttttt atggcattgg aagatattct
     2941 tttacatttc aggaaattct gtctgtaatt actaaagttg accttagtag ggttttgaaa
     3001 tgttcttgtg caatgtagtg gaagtatttt tatattaaag gtctataata agagagcatg
     3061 tttccaaact ccttggtgaa tttctgaaca agcagcttga tgtaagattg taatcttcat
     3121 ttctgttgat atatctgatt acagaacgtt gtgcacttag ctttttattt gacagagcaa
     3181 tctgattact tcagcttagt ctcaagatgg ttttccaata ttttatgatt aaatcagaac
     3241 aacctatttg aaagagcagt cttcatgaat gtgctgcttc tattgtatat tttgtgtaac
     3301 aataggctct gggtttctgt tacatattta tattttttat tttattttta taatatagac
     3361 atcacctaga tgagacacct ttaccctgtc ctgtaaaata ctaaagttac gttttcacca
     3421 acttaattgg aaagaagggg agtaaggaag caaacagcct tcaatgtgct gtggatctaa
     3481 tgtagcaatg tgtacttgtg ccaacatgta gtcactccca tcagatgaaa aagcaagaaa
     3541 gcagccagtt cttataaaat tccagcattt catgcatgta aagtgctttc accatagcaa
     3601 gaatatcaga gtctgtgcga ttaaaaggct acagtgtgtg ctcttaatcc atcctccctg
     3661 gagaagagct tgctccttca cagccaaccc aggctgtata taagctggtc acatgtatgg
     3721 attcttatga tcttcattct tggcaaatct gacttctagt gcatatactc ctttaggtct
     3781 ctgtgacaat accctttggt tcttgcctca ataaattttc tacaagtgtt ctgttcagat
     3841 tttcttaaag aaatgatgtg ccctagcttt caattgcaag agtctgacag acatttttct
     3901 tgatggtttt ccatttgcca tctctccatg tttggattta acaaagaatt tttgtactac
     3961 tgacattgga ccatgataag tgcacactct caaccatagc attcattcct ctggaatcca
     4021 agctgtagaa tcataaaagt gtgcagcact ggctgacagt gcacgcacct cttcctcctc
     4081 aggaatatgg ctcaacaaca gtggtctccc agctaggatc cctctatggt cttatagtga
     4141 gagagttgca actcaagcac atggtgcatt tctaaggaat tcacactgta gaatatttgt
     4201 tgggtccact gctcctgtct tccatatttg attgcttggg ttccagtgac ctcatatgaa
     4261 atgggcatgg gttgggaaat cttggtacgt agggaacaat tgcctgcatt aaaaagtgct
     4321 tgcataattt tgcacaattt agattcaatt gacagtctat tcagagaagt cttgggacta
     4381 aatgagcatg gagaccaaat tgccctctta ccctagaaaa gaggtggtcc cttctggtct
     4441 taccaacact ccactggccc aacactgaca aatcttgcaa tgagtcatgc agtagccttc
     4501 atctgtaggt taatagtctt ttgtctctgt tactttctct tcatagtctt ttaaccaaat
     4561 tccattacag aaagtcttac aattaaaaat aaataaaaaa aaggaaaaat taccctggca
     4621 accatttttg tgagtgggcc ttactatcaa atcatccctt attcagtgtg ggtgacattg
     4681 atagactgtg aacttctcat gaaaccagct gtctaaattt gtcaaattgt acagttttat
     4741 tgcatgtact cccattcata gtttgagtaa aaacaataag gatgcctcta gaaagtcagc
     4801 aaaagtctta aaacccaaga gcttcttttt ataactttaa aagagaagat gctccattgg
     4861 cagacgctct tctgcaaata accttggcta agatgaccag atccagagct gttttatata
     4921 gacctttccc aagtgaaaag tgacttcaag aagcaccccg aagttattgc cttttctata
     4981 aggaactatt aaaatgaaag aacaaattat ctttaaagac tgtgacccat ggatatgtaa
     5041 cccaagcaaa gaaaatcact agaatccttt ctttccatcc ttaggagaaa agtagatagc
     5101 aataactggt agatgatggt gtgactatgt gaccaattcc aaatttctct ttgaccttga
     5161 agttgatttt taattgatca taaacggttc atgaaagaca gatgggaatt gtttaaaaac
     5221 catgagatga gaaaaataaa tatttaatga tttaaaagta caaatctacc catctaacaa
     5281 agctgatgtg aatgacaaag gagaaataag ccatgtttag tatgcctgcc cactctagac
     5341 tttaggcttt gggtaccagc tgagtagaaa ccaccttcct acctgtgttg gtgcaaagtt
     5401 ctggcctgtt tcaaagcaca taaagcaatg atccaagagc taaattggca tctcattaag
     5461 atgtaaaaga gcgatagtta agaaattcca atgatagcaa aggtgattca ggccatatct
     5521 cttcatctta aaacactatt taaggtattg gaaaacactt cctaagcttc actcagaagt
     5581 ttctaccagt taactgatca atttcataat ggatgggcaa agaaaatcta tacatgttta
     5641 taaaacccac caagaaaatt atttctttac catatgtata gctctgaata gtcatgactt
     5701 ccttagttac tgtttttggg aattgttgta gaataacata ctgttattta gtatctttgt
     5761 ttctggcttg ttttattacc cgaaccacaa agtatacagc aaatctactc agggtgagaa
     5821 atgaggtcag acactgaacc tgaggtcttt caaagtacac gctaattcaa gatcttatgt
     5881 gtttctctgt tgtctcttgg cacgtgaaag aaacccagtt taagttttta agggggaaga
     5941 agtatatcag caaggtttgt gaatggtaca tcagcttatt gtctgagcat ctgtctagaa
     6001 tattacctaa ggctccacac cctacccttc tctgtaccac cactcctatc tctctacctg
     6061 tctctctttg aacctcttcc tcttccactc tcctgtattt atcttggttt tcactaaaca
     6121 gacacgtcat gtctgccaat catgaagctg tcctagagca gatgccagga cattttgttg
     6181 ttgggttttt ttgtttgttt tctgttccag aatcacattg actcaaagtt agtatcacta
     6241 agaaaagtag agaaatagct ttccaggctg cactcctaga gtaactctta aagaaatgac
     6301 aaaaagtata cacatctgct agcataggtg cttcattctg gtcttccagc aaagttacag
     6361 gaaagattag gacagttgcc ctagtagaga gcttgacctg acaggaagga cggccctagc
     6421 tagttcctac caaagtgatg accatctcta tgatatctac tttgaggaaa actattctac
     6481 atccatttgg aagaaaatta gtcccttggt aatggtggcc tcagacacat tttctctgtt
     6541 atgtggtctg tactttcaga gaacacaacc aaagttctat gcccagaaaa tgaacacatc
     6601 tatattccct gaggaatcag gtggcctgtt tctgggagga ctgacaaatt cccatcagaa
     6661 atctcctctt tccataactg aaacatgcat ttgctctctg actctctgtc atatgtgcac
     6721 aaactagcca catatctgat tactaatatg gcatagaaca agttaggaag cctaggaagg
     6781 gaagggttta catgtggaaa acgttctcag agcctgtcag atacaggtct tagccaagtt
     6841 ctacctgtct tcctcatctc catctctctg agtaacttct gggaatgatc ttgaggttgc
     6901 cttgtaggag aggccaaagg atctgtgtga gcatcaaggg gcgttagctg ctcaattccc
     6961 aatcaccatg atgctttcta gcagctttgg agagattcgt tcatttatga aattggcatt
     7021 ttttaaagtt atattaaata tgaagtgaag atctgcccat cactcacctt gctttgccat
     7081 agaatgtatt agggcatgta ccagccagtt ggaaagatgc aagcaagtaa tagattcctt
     7141 gcatcaataa aaagccttat gcctaaaatt tctcatttgt ttttgtcagt caacagcaaa
     7201 attaaaaaga aaatcaacat agtatcaatt cagtactcat cctaaggtaa tcactcatgt
     7261 acaccacaaa gtaagatatc attgtttatt tcagtttttc ctttttgaat gtttattatt
     7321 tatagattca aaatagatat acccatatgc tggcaagtga acatcccata tatattatct
     7381 gttggctatc attttttaaa taaaaagaac attttattat ctaatatatg tatatatatc
     7441 atctattata tatacatata atatatacat atgtgtgcat gtatacatgt ttatatgtat
     7501 atatgtgtgt atgtatataa tatataatat atacatacat acattaagga aaatgaaata
     7561 ggttgtgatg gaaaattgat agtggccaaa tataagcttt ttctttacag ttagaagttc
     7621 agtcttgaac atttctttct gtactgaaaa ataactagtc agtagtttcc attcatatga
     7681 ataaggtatg attaggcttg gtatggtctg cgccagaaca aacatcggat atttttttac
     7741 tccataatct taaaatctga ggcatgactt tcctggaatg aactaagaat ccatgcttat
     7801 aaggttcact tcataatatt atttttgata aactaaactg acagctttat gagagatcat
     7861 atatccccca tatcttgttc tagtcagagg atgtgtgtga acatgagtgg cactaagaac
     7921 catgaagtac taaggtgggt aatactgaag taatgtggaa ttttagaaac tggatgccct
     7981 aagacatgct acaacagact actattcgaa atgaatctat caaattgcaa cgaatatttt
     8041 atagaattat gaccatgagc atgaaagact tctagtagga aaatcttgtg tcttccttgg
     8101 atttaactgt gattggtttg ttggtgattg gtgttgagga gttttgtgtt ctgctcttct
     8161 cagacatttc agtgttccac attgtccatt tccttcaagc tgttgaaatt taaagcagtc
     8221 tgtttataat cttacaagat tatgagaatc ttataagatt cagaaacaat ccatcctcag
     8281 gtttctgtta atacactaat aagaggcaga aggaagagcc cagatgcacg tttaaaggat
     8341 cagaattagc ataggaactg ttacaatttc tagactgtct ccagaaatta atatgcatag
     8401 gtactggctc acaggacctt cttgagtttg cactaatctg gctcactaaa tcagtttgta
     8461 aagacatgca gttttccttg attggtcctc tactattcag ccccccatgt attcattaac
     8521 gcaatataaa tgctgaagtg cctcgcatga cttcacgctg tagagagggg aaggcacctg
     8581 caagggcagc accggaagct cactgggatg attgacacgt tggaggcaaa agagcacatg
     8641 caaccggctc cagcttggct cagctttaga ctccaggagt ttacaagtag tacagatggc
     8701 ctcaagtaca tctgtgtgta tttgtacatg tgcacacacc catgtatata tatttatcta
     8761 tctgtacaaa cactacatat gtatacacac tatctatgta atatataata tatgtataat
     8821 gcatataaat tctaacaagt gtatttgtgt tatctttaaa atagaacaat tgtatcttga
     8881 aatggtaaat gcagagactt ggctttattg ttgatctgtg gatttaatga atttttaggt
     8941 gaaaggatgt tttaagtgta taatttcttt tcttaattta atatatttat gtaaatgcat
     9001 gcctgaaatt tgattagatt ggctgttctt ttgtgtctta acatgatcaa atgtattaaa
     9061 ctttatctta tgacttcaaa aaaaaaaaaa aaaa
//
