LOCUS       NM_027658               1928 bp    mRNA    linear   ROD 23-APR-2024
DEFINITION  Mus musculus hexamethylene bis-acetamide inducible 2 (Hexim2),
            transcript variant 1, mRNA.
ACCESSION   NM_027658 XM_203501 XM_903070 XM_906311 XM_985837
VERSION     NM_027658.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1928)
  AUTHORS   Okamura,D., Maeda,I., Taniguchi,H., Tokitake,Y., Ikeda,M.,
            Ozato,K., Mise,N., Abe,K., Noce,T., Izpisua Belmonte,J.C. and
            Matsui,Y.
  TITLE     Cell cycle gene-specific control of transcription has a critical
            role in proliferation of primordial germ cells
  JOURNAL   Genes Dev 26 (22), 2477-2482 (2012)
   PUBMED   23154982
REFERENCE   2  (bases 1 to 1928)
  AUTHORS   Galatioto,J., Mascareno,E. and Siddiqui,M.A.
  TITLE     CLP-1 associates with MyoD and HDAC to restore skeletal muscle cell
            regeneration
  JOURNAL   J Cell Sci 123 (Pt 21), 3789-3795 (2010)
   PUBMED   20940258
REFERENCE   3  (bases 1 to 1928)
  AUTHORS   Montano,M.M., Doughman,Y.Q., Deng,H., Chaplin,L., Yang,J., Wang,N.,
            Zhou,Q., Ward,N.L. and Watanabe,M.
  TITLE     Mutation of the HEXIM1 gene results in defects during heart and
            vascular development partly through downregulation of vascular
            endothelial growth factor
  JOURNAL   Circ Res 102 (4), 415-422 (2008)
   PUBMED   18079413
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY295186.1, BC026458.1 and BI076707.2.
            
            On Jul 26, 2008 this sequence version replaced NM_027658.1.
            
            Transcript Variant: This variant (1) represents the longest
            transcript.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC026458.1, BG261997.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849378
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-4                 BY295186.1         2-5
            5-1896              BC026458.1         1-1892
            1897-1928           BI076707.2         1-32                c
FEATURES             Location/Qualifiers
     source          1..1928
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 66.71 cM"
     gene            1..1928
                     /gene="Hexim2"
                     /gene_synonym="4933402L21Rik"
                     /note="hexamethylene bis-acetamide inducible 2"
                     /db_xref="GeneID:71059"
                     /db_xref="MGI:MGI:1918309"
     exon            1..99
                     /gene="Hexim2"
                     /gene_synonym="4933402L21Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            100..206
                     /gene="Hexim2"
                     /gene_synonym="4933402L21Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             144..1085
                     /gene="Hexim2"
                     /gene_synonym="4933402L21Rik"
                     /note="hexamthylene bis-acetamide inducible 2"
                     /codon_start=1
                     /product="protein HEXIM2"
                     /protein_id="NP_081934.1"
                     /db_xref="CCDS:CCDS25514.1"
                     /db_xref="GeneID:71059"
                     /db_xref="MGI:MGI:1918309"
                     /translation="MATVNHTNCNTASPAALEEAKTSGGLRSPQIAHEPHDFGGSQLL
                     PSGQEIQSEDEGTVPAGDGSSCNIRGSRTQSPGGCSVEAVLARKKHRRRPSKRKRHWR
                     PYLELSWAEKQQRDERQSQRASRVREEMFAKGQPLAPYNTTQFLMNDRDLEEPNLDVL
                     HGPSHSGSGGENEAGDSDGQGRAHGEFQQRDFSEAYERYHTESLQGRSKQELVRDYLD
                     LERRLSQAEQETRRLRQLQGCSSRQPCQQVEELAAEVERLRTENQRLRQENEMWNREG
                     GYCDQEKPASEGTPWPKVEAPFQTHTGQLGHREAGDR"
     exon            207..1928
                     /gene="Hexim2"
                     /gene_synonym="4933402L21Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1189..1194
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hexim2"
                     /gene_synonym="4933402L21Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1231
                     /gene="Hexim2"
                     /gene_synonym="4933402L21Rik"
                     /note="major polyA site"
     regulatory      1895..1900
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hexim2"
                     /gene_synonym="4933402L21Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1924
                     /gene="Hexim2"
                     /gene_synonym="4933402L21Rik"
                     /note="major polyA site"
ORIGIN      
        1 aagagatagg gcagaggcgt tgagactctc atggacaggc ggtcgcacag aaagacacac
       61 agaggtagtg gtgtacacta agcccttgac agcaaatagg tgacagtagt taaagacatc
      121 atctgctgca agagtaggag aagatggcca ctgtgaacca taccaactgc aacacagcgt
      181 caccagctgc tctggaggag gccaagactt ccggtggtct tcggagcccc cagatagccc
      241 atgagcctca tgacttcggt ggttcccagc ttctgccatc aggacaggag atccaatcag
      301 aggatgaagg gactgtcccc gctggcgatg gctcaagttg taacattagg ggttctcgaa
      361 cccagagccc agggggctgt tcggtggagg cggtgctggc ccgaaagaag caccgtaggc
      421 ggccatcgaa gcgcaagcgg cactggcggc cctacttgga gctgagctgg gccgagaagc
      481 aacagcgaga tgagaggcag agccagaggg cctctcgggt ccgtgaggag atgttcgcca
      541 aaggtcagcc cctggcgccc tacaacacca cccagttcct catgaatgat cgtgacctgg
      601 aggagcctaa cctcgatgtg cttcacgggc cctcccactc tggctccggt ggggagaacg
      661 aagcagggga cagtgatggg caaggccgag cccatgggga atttcagcag agggacttct
      721 ctgaggccta tgagcggtac cacactgaga gccttcaggg ccgcagcaag caggagctgg
      781 tgcgagacta cctggatcta gagaggcgtc tgtcacaggc tgagcaggaa actcggaggc
      841 tccggcagct gcagggttgc tccagcaggc aaccctgtca acaggtggaa gagctggctg
      901 ctgaggtgga gaggctcaga actgaaaacc agcggctgcg tcaggagaac gagatgtgga
      961 accgagaggg cggctactgt gaccaggaga aaccagcctc agaagggacc ccttggccca
     1021 aggttgaagc cccatttcag acccacacag gccagctggg tcatagggag gcaggtgaca
     1081 gatgaaagct actccctgtc tccactgaga actgctaaga caaggtcaga gtttcccctg
     1141 ccattttcat ggttggatct ttaatgtcat ctaacttttt acacagcaat taaacaacct
     1201 tgtgagagcc agtgagagtg gctacaattg atttcactgg ggctcttctt gtgttcaagc
     1261 ttcctttttt atttttaaaa aagtactgtg caccacatgt gcagaggcca gaagagacct
     1321 ttggatcccc ttgggactgg agttgcagac agttgttagc tgccctgtgg gtgctggcaa
     1381 ctctacctgg gtcctctgga agagaagggg cccctaactt ccgagtcgcc cctccagccc
     1441 tcttcatttt ctaaagtttc tttgtattct ggaggagttt cagatagctg aggctagcct
     1501 gcctgatctt ccttcacttc cccagatgtg ggattgcaga tgggcaccac tcactctgcc
     1561 cggcttgtgt catgctgtgg ctcaaacaca gggcttcgtg gatgctaagc aagagctctg
     1621 gcaactgcag cagcacgtct ccagccagag ctgagaggtg atgggtcagg gtgaagagac
     1681 cgacctcact gttctcttag aggactgcag tttggtttcc tccatctatc tgcaggtgac
     1741 tcacaactgt gtgtaactgc agctcctgag gatctcgtgt cctcttttga cctcttgtca
     1801 cacacacacg cacacacaca cacacacaca tgtatgtaca tacctatgta gtgcatatgc
     1861 acacataaat atgtaaagac gaaatcctgc aaaaaataaa aagaacttgt ggcctgggaa
     1921 taaaggtt
//
