LOCUS       NM_178899               2134 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus HEPACAM family member 2 (Hepacam2), transcript variant
            1, mRNA.
ACCESSION   NM_178899
VERSION     NM_178899.6
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2134)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2134)
  AUTHORS   Gu,Z., Imai,F., Kim,I.J., Fujita,H., Katayama,Ki., Mori,K.,
            Yoshihara,Y. and Yoshida,Y.
  TITLE     Expression of the immunoglobulin superfamily cell adhesion
            molecules in the developing spinal cord and dorsal root ganglion
  JOURNAL   PLoS One 10 (3), e0121550 (2015)
   PUBMED   25826454
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 2134)
  AUTHORS   Hald,J., Galbo,T., Rescan,C., Radzikowski,L., Sprinkel,A.E.,
            Heimberg,H., Ahnfelt-Ronne,J., Jensen,J., Scharfmann,R.,
            Gradwohl,G., Kaestner,K.H., Stoeckert,C. Jr., Jensen,J.N. and
            Madsen,O.D.
  TITLE     Pancreatic islet and progenitor cell surface markers with cell
            sorting potential
  JOURNAL   Diabetologia 55 (1), 154-165 (2012)
   PUBMED   21947380
REFERENCE   4  (bases 1 to 2134)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   5  (bases 1 to 2134)
  AUTHORS   Hoffman,B.G., Zavaglia,B., Witzsche,J., Ruiz de Algara,T.,
            Beach,M., Hoodless,P.A., Jones,S.J., Marra,M.A. and Helgason,C.D.
  TITLE     Identification of transcripts with enriched expression in the
            developing and adult pancreas
  JOURNAL   Genome Biol 9 (6), R99 (2008)
   PUBMED   18554416
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC022453.5.
            
            On Aug 26, 2022 this sequence version replaced NM_178899.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC096374.1, AK033728.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-110               AC022453.5         197542-197651       c
            111-464             AC022453.5         190065-190418       c
            465-749             AC022453.5         186432-186716       c
            750-1046            AC022453.5         179051-179347       c
            1047-1172           AC022453.5         170766-170891       c
            1173-1197           AC022453.5         170656-170680       c
            1198-1235           AC022453.5         170531-170568       c
            1236-1309           AC022453.5         169266-169339       c
            1310-1419           AC022453.5         166403-166512       c
            1420-2134           AC022453.5         160344-161058       c
FEATURES             Location/Qualifiers
     source          1..2134
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 1.8 cM"
     gene            1..2134
                     /gene="Hepacam2"
                     /note="HEPACAM family member 2"
                     /db_xref="GeneID:101202"
                     /db_xref="MGI:MGI:2141520"
     exon            1..110
                     /gene="Hepacam2"
                     /inference="alignment:Splign:2.1.0"
     CDS             32..1423
                     /gene="Hepacam2"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; mitotic kinetics regulator"
                     /codon_start=1
                     /product="HEPACAM family member 2 isoform 1 precursor"
                     /protein_id="NP_849230.1"
                     /db_xref="CCDS:CCDS39414.1"
                     /db_xref="GeneID:101202"
                     /db_xref="MGI:MGI:2141520"
                     /translation="MGQDAFMELLRSMVGLSLCKIHLLLIAGSCLGLKVTVPSYTVHG
                     IRGQALYLPVHYGFHTPASDIQIIWLFERSHTMPKYLLGSVNKSVVPDLEYQHKFTMM
                     PPNASLLINPLQFTDEGNYIVKVNIQGNGTLSASQKIQVTVDDPVMKPMVQFHPASGA
                     VEYVGNITLTCQVEGGTRLVYQWRKSGKPISINSSHSFSPQNNTLWIVPVTKEDIGNY
                     TCLVSNPVSEMESDIIMPTIYYGPYGLQVNSDKGLKVGEVFTVDLGEAVLFDCSADSY
                     PPNTYSWIQRSDNTTHVIKHGPHLEVASEKVAQKTADYVCCAYNNITGRRDETRFTVI
                     ITSVGLEKLAQRGKSLSPLASITGISLFLIISMCLLFLWKKYQPYKAIRQKLEGRPES
                     EYRKAQTFSGHEDALSDFGIYEFVTFPDASGVSRMSSRSSPASDGVTGQDIHGTIYEV
                     IQHIPEQQQENTE"
     exon            111..464
                     /gene="Hepacam2"
                     /inference="alignment:Splign:2.1.0"
     exon            465..749
                     /gene="Hepacam2"
                     /inference="alignment:Splign:2.1.0"
     exon            750..1046
                     /gene="Hepacam2"
                     /inference="alignment:Splign:2.1.0"
     exon            1047..1172
                     /gene="Hepacam2"
                     /inference="alignment:Splign:2.1.0"
     exon            1173..1197
                     /gene="Hepacam2"
                     /inference="alignment:Splign:2.1.0"
     exon            1198..1235
                     /gene="Hepacam2"
                     /inference="alignment:Splign:2.1.0"
     exon            1236..1309
                     /gene="Hepacam2"
                     /inference="alignment:Splign:2.1.0"
     exon            1310..1419
                     /gene="Hepacam2"
                     /inference="alignment:Splign:2.1.0"
     exon            1420..2134
                     /gene="Hepacam2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2109..2114
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hepacam2"
                     /note="hexamer: AATAAA"
     polyA_site      2134
                     /gene="Hepacam2"
                     /note="major polyA site"
ORIGIN      
        1 aacttgccac tgagaacagg gcgccgcatg catgggacag gatgctttta tggagcttct
       61 cagaagcatg gttgggctct ctctttgcaa aatacacctt cttcttatag caggttcttg
      121 tctgggactg aaggtgaccg tgccgtcata cactgtccac ggcatcaggg gacaggccct
      181 ctaccttcca gtgcactatg gcttccacac tccagcatct gacatccaga tcatatggct
      241 gtttgaaaga tcccacacaa tgcccaaata cttgctaggc tccgttaata agtctgtggt
      301 tcctgacttg gaataccagc acaagttcac catgatgcca cccaatgcat ctctgctcat
      361 caacccgctg cagttcaccg atgagggcaa ttacatcgtg aaggtcaaca tccaggggaa
      421 tggaactctg tctgcaagtc agaagataca agtcactgtc gatgatcctg tcatgaagcc
      481 aatggttcag ttccatcctg cttctggggc tgttgagtat gtgggcaaca ttaccttgac
      541 ctgccaggta gaaggaggta ccaggctggt ttaccagtgg cgaaaaagtg ggaaacccat
      601 ttccatcaac tccagccact ctttttctcc ccaaaacaac accctttgga ttgttccagt
      661 gacaaaagaa gacattggaa actacacctg cctcgtgtca aaccccgtca gtgagatgga
      721 aagtgatatc attatgccca ccatatatta tggaccttat ggacttcagg ttaattctga
      781 taaagggcta aaagtgggag aagtattcac tgttgacctg ggagaagctg tcctctttga
      841 ctgttcagct gattcttatc cccctaacac ctactcctgg atccaaagat ctgacaatac
      901 tacacatgtc attaagcatg ggcctcattt agaagttgca tctgagaaag tggcccagaa
      961 gacagctgac tatgtgtgct gtgcttacaa caacatcacc ggaagacgcg atgaaactcg
     1021 attcacagtc atcataactt ccgtaggact ggagaagctt gcacaaaggg gaaaatccct
     1081 gtccccacta gcaagtataa ctggaatatc actgtttttg attatatcca tgtgccttct
     1141 ttttctgtgg aaaaaatatc aaccttacaa agctataaga cagaagctag aaggcagacc
     1201 agagtcagaa tacagaaaag ctcaaacatt ttcaggccat gaagatgccc tgagtgactt
     1261 cgggatctac gagtttgtga cttttccgga tgcatctggt gtttccagga tgtcaagtag
     1321 gtcttcccct gcctctgatg gtgtaacagg gcaagatatt cacggaacaa tttatgaagt
     1381 cattcagcat atcccagaac aacagcaaga aaatacagag tgagattcaa tgggcaaaat
     1441 agtatattgg agtaaaatca caaagaaaca ttttgaaagg aaacatctgg aatctgtgaa
     1501 aaatacaatc ctagcaacct tcagttacat cttgatgcag agtagaggcg cctgtgcaga
     1561 ctgaaggctg gttttctgac gtgcgcaatg ggctgtgtga cagaggaaca ccgtaggaat
     1621 attcttccgt ggacagttta tcacccagac tgggaggaag aagagaacga agctccctag
     1681 ttacttgcta ctgaaacttc caagcgttcc aactggggct cgcccatgct cctccactcg
     1741 gatcagtgaa gcactactct gtgtcacctg caaactccgg ggtttcacct tggtagatgt
     1801 tcgcaataag ctttgtttta ttaagtgctc attactgtta tgaaagtaaa accacctttt
     1861 ttttcccttt gtcccaaatt gatttcttgt tgtttgtgtc acaaaaaatt aaggatgctt
     1921 aacacagagg taagactgtg ccttttccct ggctctcagt gaactttggt atcaacagtg
     1981 tatttggaaa gacaggcaaa atggtttttt gtttgtttgg ttggtttgtt ttggttggtt
     2041 tgtttggttg ttttgtttgg tttgttaaaa tctcattttg atttttgttc aaagaaagaa
     2101 aaaattgaaa taaagtattc tgtttgcctt ttta
//
