LOCUS       NM_144788               8830 bp    mRNA    linear   ROD 12-AUG-2024
DEFINITION  Mus musculus HECT domain E3 ubiquitin protein ligase 1 (Hectd1),
            transcript variant 1, mRNA.
ACCESSION   NM_144788 XM_915167 XM_974905
VERSION     NM_144788.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8830)
  AUTHORS   Xing,Y., Li,P., Jia,Y., Zhang,K., Liu,M. and Jiang,J.
  TITLE     Dorsal root ganglion-derived exosomes deteriorate neuropathic pain
            by activating microglia via the microRNA-16-5p/HECTD1/HSP90 axis
  JOURNAL   Biol Res 57 (1), 28 (2024)
   PUBMED   38750549
  REMARK    GeneRIF: Dorsal root ganglion-derived exosomes deteriorate
            neuropathic pain by activating microglia via the
            microRNA-16-5p/HECTD1/HSP90 axis.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8830)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 8830)
  AUTHORS   Liao,S., Zheng,Q., Shen,H., Yang,G., Xu,Y., Zhang,X., Ouyang,H. and
            Pan,Z.
  TITLE     HECTD1-Mediated Ubiquitination and Degradation of Rubicon Regulates
            Autophagy and Osteoarthritis Pathogenesis
  JOURNAL   Arthritis Rheumatol 75 (3), 387-400 (2023)
   PUBMED   36121967
  REMARK    GeneRIF: HECTD1-Mediated Ubiquitination and Degradation of Rubicon
            Regulates Autophagy and Osteoarthritis Pathogenesis.
REFERENCE   4  (bases 1 to 8830)
  AUTHORS   Zeng,X., Dong,X., Xiao,Q. and Yao,J.
  TITLE     Vitamin C Inhibits Ubiquitination of Glutamate Transporter 1
            (GLT-1) in Astrocytes by Downregulating HECTD1
  JOURNAL   ACS Chem Neurosci 13 (5), 676-687 (2022)
   PUBMED   35148069
  REMARK    GeneRIF: Vitamin C Inhibits Ubiquitination of Glutamate Transporter
            1 (GLT-1) in Astrocytes by Downregulating HECTD1.
REFERENCE   5  (bases 1 to 8830)
  AUTHORS   Harris,L.D., Le Pen,J., Scholz,N., Mieszczanek,J., Vaughan,N.,
            Davis,S., Berridge,G., Kessler,B.M., Bienz,M. and Licchesi,J.D.F.
  TITLE     The deubiquitinase TRABID stabilizes the K29/K48-specific E3
            ubiquitin ligase HECTD1
  JOURNAL   J Biol Chem 296, 100246 (2021)
   PUBMED   33853758
REFERENCE   6  (bases 1 to 8830)
  AUTHORS   Garcia-Garcia,M.J., Eggenschwiler,J.T., Caspary,T., Alcorn,H.L.,
            Wyler,M.R., Huangfu,D., Rakeman,A.S., Lee,J.D., Feinberg,E.H.,
            Timmer,J.R. and Anderson,K.V.
  TITLE     Analysis of mouse embryonic patterning and morphogenesis by forward
            genetics
  JOURNAL   Proc Natl Acad Sci U S A 102 (17), 5913-5919 (2005)
   PUBMED   15755804
REFERENCE   7  (bases 1 to 8830)
  AUTHORS   Okazaki,N., F-Kikuno,R., Ohara,R., Inamoto,S., Koseki,H.,
            Hiraoka,S., Saga,Y., Seino,S., Nishimura,M., Kaisho,T., Hoshino,K.,
            Kitamura,H., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
REFERENCE   8  (bases 1 to 8830)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 8830)
  AUTHORS   Araki,K., Imaizumi,T., Sekimoto,T., Yoshinobu,K., Yoshimuta,J.,
            Akizuki,M., Miura,K., Araki,M. and Yamamura,K.
  TITLE     Exchangeable gene trap using the Cre/mutated lox system
  JOURNAL   Cell Mol Biol (Noisy-le-grand) 45 (5), 737-750 (1999)
   PUBMED   10512203
REFERENCE   10 (bases 1 to 8830)
  AUTHORS   Kasarskis,A., Manova,K. and Anderson,K.V.
  TITLE     A phenotype-based screen for embryonic lethal mutations in the
            mouse
  JOURNAL   Proc Natl Acad Sci U S A 95 (13), 7485-7490 (1998)
   PUBMED   9636176
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC157213.2 and AC159644.3.
            
            On Apr 21, 2022 this sequence version replaced NM_144788.2.
            
            Sequence Note:.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMN00849374, SAMN00849375
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-175               AC157213.2         133560-133734
            176-337             AC157213.2         135424-135585
            338-572             AC157213.2         156341-156575
            573-800             AC157213.2         159041-159268
            801-1082            AC157213.2         160121-160402
            1083-1353           AC157213.2         160503-160773
            1354-1430           AC157213.2         161965-162041
            1431-1529           AC157213.2         162124-162222
            1530-1644           AC157213.2         164169-164283
            1645-1819           AC157213.2         164926-165100
            1820-1958           AC159644.3         194764-194902       c
            1959-2129           AC159644.3         194439-194609       c
            2130-2352           AC159644.3         191245-191467       c
            2353-2616           AC159644.3         190377-190640       c
            2617-2693           AC159644.3         190197-190273       c
            2694-2828           AC159644.3         187870-188004       c
            2829-2975           AC159644.3         185834-185980       c
            2976-3070           AC159644.3         184207-184301       c
            3071-3176           AC159644.3         182507-182612       c
            3177-3311           AC159644.3         176521-176655       c
            3312-3451           AC159644.3         174676-174815       c
            3452-3775           AC159644.3         173852-174175       c
            3776-3942           AC159644.3         172564-172730       c
            3943-4119           AC159644.3         172299-172475       c
            4120-4956           AC159644.3         168554-169390       c
            4957-5178           AC159644.3         167581-167802       c
            5179-5312           AC159644.3         164046-164179       c
            5313-5435           AC159644.3         162449-162571       c
            5436-5592           AC159644.3         161039-161195       c
            5593-5815           AC159644.3         159244-159466       c
            5816-5870           AC159644.3         157072-157126       c
            5871-6053           AC159644.3         154946-155128       c
            6054-6261           AC159644.3         154240-154447       c
            6262-6347           AC159644.3         154068-154153       c
            6348-6475           AC159644.3         153766-153893       c
            6476-6677           AC159644.3         151881-152082       c
            6678-6815           AC159644.3         150346-150483       c
            6816-7423           AC159644.3         148429-149036       c
            7424-7502           AC159644.3         146298-146376       c
            7503-7596           AC159644.3         146119-146212       c
            7597-7747           AC159644.3         145406-145556       c
            7748-7892           AC159644.3         144791-144935       c
            7893-8830           AC159644.3         143746-144683       c
FEATURES             Location/Qualifiers
     source          1..8830
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="12"
                     /map="12 22.11 cM"
     gene            1..8830
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /note="HECT domain E3 ubiquitin protein ligase 1"
                     /db_xref="GeneID:207304"
                     /db_xref="MGI:MGI:2384768"
     exon            1..175
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            176..337
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     CDS             198..8030
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /EC_number="2.3.2.26"
                     /note="isoform 1 is encoded by transcript variant 1; E3
                     ubiquitin-protein ligase HECTD1; protein open mind; HECT
                     domain-containing protein 1; HECT-type E3 ubiquitin
                     transferase HECTD1; HECT domain containing 1"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase HECTD1 isoform 1"
                     /protein_id="NP_659037.2"
                     /db_xref="CCDS:CCDS49064.1"
                     /db_xref="GeneID:207304"
                     /db_xref="MGI:MGI:2384768"
                     /translation="MADVDPDTLLEWLQMGQGDERDMQLIALEQLCMLLLMSDNVDRC
                     FETCPPRTFLPALCKIFLDESAPDNVLEVTARAITYYLDVSAECTRRIVGVDGAIKAL
                     CNRLVVVELNNRTSRDLAEQCVKVLELICTRESGAVFEAGGLNCVLTFIRDSGHLVHK
                     DTLHSAMAVVSRLCGKMEPQDSSLEICVESLSSLLKHEDHQVSDGALRCFASLADRFT
                     RRGVDPAPLAKHGLTEELLSRMAAAGGTVSGPSSACKPGRSTTGAPSAAADSKLSNQV
                     STIVSLLSTLCRGSPLVTHDLLRSELPDSIESALQGDERCVLDTMRLVDLLLVLLFEG
                     RKALPKSSAGSTGRIPGLRRLDSSGERSHRQLIDCIRSKDTDALIDAIDTGAFEVNFM
                     DDVGQTLLNWASAFGTQEMVEFLCERGADVNRGQRSSSLHYAACFGRPQVAKTLLRHG
                     ANPDLRDEDGKTPLDKARERGHSEVVAILQSPGDWMCPVNKGDDKKKKDTNKDEEECN
                     EPRGDPEMAPLYLKRLLPVFAQTFQHTMLPSIRKASLALIRKMIHFCSEALLKEVCDS
                     DVGHNLPTTLVEITATVLDQEDDDDGHLLALQIIRDLVDKGGDIFLDQLARLGVISKV
                     SALAGPSSDDENEEESKPEKEDEPQEDAKELQQGKPYHWRDWSIIRGRDCLYIWSDAA
                     ALELSNGSNGWFRFILDGKLATMYSSGSPEGGSDSSESRSEFLEKLQRARGQVKPSTS
                     SQPILSAPGPTKLTVGNWSLTCLKEGEIAIHNSDGQQATILKEDLPGFVFESNRGTKH
                     SFTAETSLGSEFVTGWTGKRGRKLKSKLEKTKQKVRTMARDLYDDHFKAVESMPRGVV
                     VTLRNIATQLESSWELHTNRQCIEGENTWRDLMKTALENLIVLLKDENTISPYEMCSS
                     GLVQALLTVLNNSIDLDMKQDCSQLVERINVFKTAFSESEDDESRPAVALIRKLIAVL
                     ESIERLPLHLYDTPGSTYNLQILTRRLRFRLERAPGETSLIDRTGRMLKMEPLATVES
                     LEQYLLKMVAKQWYDFDRSSFVFVRKLREGQNFIFRHQHDFDENGIIYWIGTNAKTAY
                     EWVNPAAYGLVVVTSSEGRNLPYGRLEDILSRDNSALNCHSNDDKNAWFAIDLGVWVI
                     PSAYTLRHARGYGRSALRNWVFQVSKDGQNWTSLYTHVDDCSLNEPGSTATWPLDPAK
                     DEKQGWRHVRLKQMGKNASGQTHYLSLSGFELYGTVNGVCEDQLGKAAKEAEANLRRQ
                     RRLVRSQVLKYMVPGARVIRGLDWKWRDQDGSPQGEGTVTGELHNGWIDVTWDAGGSN
                     SYRMGAEGKFDLKLAPGYDPDTVASPKPVSSTVSGTTQSWSSLVKNNCPDKTSAAAGS
                     SSRKGSSSSVCSVASSSDISLASTKTERRSEIVMEHSIVSGADVHEPIVVLSSAENVP
                     QTEVGSSSSASTSTLTAETGSENAERKLGPDSSVRAPGESSAISMGIVSVSSPDVSSV
                     SELTNKEAASQRPLSSSASNRLSVSSLLAAGAPMSSSASVPNLSSRETSSLESFVRRV
                     ANIARTNATNNMNLSRSSSDNNTNTLGRNVMSTATSPLMGAQSFPNLTTPGTTSTVTM
                     STSSVTSSSNVATATTVLSVGQSLSNTLTTSLTSTSSESDTGQEAEYSLYDFLDSCRA
                     STLLAELDDDEDLPEPDEEDDENEDDNQEDQEYEEVMILRRPSLQRRAGSRSDVTHHV
                     VTSQLPQVPSGAGSRPVGEQEEEEYETKGGRRRAWDDDYVLKRQFSALVPAFDPRPGR
                     TNVQQTTDLEIPPPGTPHSELLEEVECTPSPRLALTLKVTGLGTTREVELPLTNFRST
                     IFYYVQKLLQLSCNGNVKSDKLRRIWEPTYTIMYREMKDSDKEKENGKMGCWSIEHVE
                     QYLGTDELPKNDLITYLQKNADAAFLRHWKLTGTNKSIRKNRNCSQLIAAYKDFCEHG
                     TKSGLNQGAISSLQSSDILNLTKEQPQAKAGNGQSPCGVEDVLQLLRILYIVASDPYS
                     RISQEDGDEQPQFTFPPDEFTSKKITTKILQQIEEPLALASGALPDWCEQLTSKCPFL
                     IPFETRQLYFTCTAFGASRAIVWLQNRREATVERTRTTSSVRRDDPGEFRVGRLKHER
                     VKVPRGESLMEWAENVMQIHADRKSVLEVEFLGEEGTGLGPTLEFYALVAAEFQRTDL
                     GTWLCDDNFPDDESRHVDLGGGLKPPGYYVQRSCGLFTAPFPQDSDELERITKLFHFL
                     GIFLAKCIQDNRLVDLPISKPFFKLMCMGDIKSNMSKLIYESRGDRDLHCTESQSEAS
                     TEEGHDSLSVGSFEEDSKSEFILDPPKPKPPAWFNGILTWEDFELVNPHRARFLKEIK
                     DLAIKRRQILGNKSLSEDEKNTKLQELVLRNPSGSGPPLSIEDLGLNFQFCPSSRIYG
                     FTAVDLKPSGEDEMITMDNAEEYVDLMFDFCMHTGIQKQMEAFRDGFNKVFPMEKLSS
                     FSHEEVQMILCGNQSPSWAAEDIINYTEPKLGYTRDSPGFLRFVRVLCGMSSDERKAF
                     LQFTTGCSTLPPGGLANLHPRLTVVRKVDATDASYPSVNTCVHYLKLPEYSSEEIMRE
                     RLLAATMEKGFHLN"
     exon            338..572
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            573..800
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            801..1082
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            1083..1353
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            1354..1430
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            1431..1529
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            1530..1644
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            1645..1819
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            1820..1958
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            1959..2129
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            2130..2352
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            2353..2616
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            2617..2693
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            2694..2828
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            2829..2975
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            2976..3070
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            3071..3176
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            3177..3311
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            3312..3451
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            3452..3775
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            3776..3942
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            3943..4119
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            4120..4956
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            4957..5178
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            5179..5312
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            5313..5435
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            5436..5592
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            5593..5815
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            5816..5870
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            5871..6053
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            6054..6261
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            6262..6347
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            6348..6475
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            6476..6677
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            6678..6815
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            6816..7423
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            7424..7502
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            7503..7596
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            7597..7747
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            7748..7892
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     exon            7893..8830
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8811..8816
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /note="hexamer: ATTAAA"
     polyA_site      8830
                     /gene="Hectd1"
                     /gene_synonym="A630086P08Rik; b2b327Clo; opm"
                     /note="major polyA site"
ORIGIN      
        1 caccgggtcc ccgcggagga aggggaggga cgagacacgg cttttcctgt gccgcctgcc
       61 tggctcgacc tgcgcggcct gcggtttcct aggaactcga gggccgcggc cgggccaggc
      121 tctgcccgcg gcctgcttgg agctggaccg gagctgtttg gtacggcgag ccagggcaaa
      181 ggagcatttt aaagacaatg gcagatgtag atcctgatac gttgctggaa tggctgcaga
      241 tgggacaggg agatgaaagg gacatgcagc taatagccct ggagcagcta tgcatgctgc
      301 ttttgatgtc tgacaatgtg gatcgctgtt ttgaaacatg tccacctcgt actttcctgc
      361 cagctctctg caaaattttc cttgatgaaa gtgctccaga caatgtctta gaggtgacag
      421 cccgtgccat aacatactac ctggatgttt ctgcagaatg cacccggagg atagtagggg
      481 tggatggagc tataaaagca ctttgtaatc gcttggtggt agttgaactt aacaacagga
      541 ccagcagaga tttagctgaa cagtgtgtaa aggtgctgga actgatctgc acgcgtgagt
      601 caggggcagt ctttgaggct ggtggtttga attgtgttct caccttcatt cgtgacagcg
      661 gacacctcgt tcataaagat acattacact ctgcgatggc tgtggtatcg agactctgtg
      721 gcaaaatgga gcctcaggat tcctctttag aaatttgtgt agagtctcta tctagtttat
      781 taaagcatga agatcatcag gtttccgatg gagctctgcg gtgttttgca tcactagctg
      841 accggtttac tcgtcgtggg gtagacccag ctccattggc caagcatgga ttaactgagg
      901 agctgttgtc tcgaatggca gcggctggtg gtactgtatc aggaccatct tcagcatgca
      961 aaccaggtcg cagtaccaca ggagccccct ctgctgctgc agattccaaa ttgagtaacc
     1021 aggtgtcgac aattgtaagt ctcctctcaa cgctttgcag aggctctcca ctagtaacac
     1081 acgatcttct gaggtcagag cttccagatt caatcgaaag tgcattacag ggtgatgaaa
     1141 gatgtgtgct tgataccatg cgtctggttg acctcctctt ggtgctgtta tttgaaggac
     1201 gaaaggcttt gcctaagtct agtgctggat ctacaggcag aatcccagga ctgcggagat
     1261 tggatagttc tggggagcgc tcccatcggc agcttataga ctgtattcga agtaaagata
     1321 ctgatgctct catagatgcg attgacacag gagcctttga agtcaatttt atggatgatg
     1381 tgggtcagac tctattaaac tgggcctctg cgtttggaac tcaggaaatg gtagaatttc
     1441 tttgtgagag gggtgctgat gttaatagag gccaaaggtc ctcctcatta cactatgctg
     1501 catgttttgg aagacctcaa gtagcaaaga ctctgttacg gcatggtgca aatccggatc
     1561 tcagagatga agatgggaaa acaccattgg ataaagctcg agaaagaggc cacagtgaag
     1621 tagtagcaat tctccagtct ccaggtgatt ggatgtgtcc agttaataaa ggggatgaca
     1681 aaaaaaagaa agatacaaac aaagatgaag aggaatgcaa tgaacccaga ggggatccag
     1741 aaatggcacc gctctacttg aagaggttgc tgccagtgtt tgcacagaca tttcagcaca
     1801 ctatgctgcc ttcaataagg aaagccagtc ttgctttaat ccgaaaaatg attcattttt
     1861 gctctgaagc actgttaaaa gaagtttgtg attctgacgt tggtcacaat ttgcccacaa
     1921 cactagtgga aatcactgca actgtccttg atcaagagga tgatgatgat ggccacttgc
     1981 tagctttgca gatcataagg gatctagtag ataaaggtgg tgatattttt ttggatcagc
     2041 ttgccagact tggtgtaatt agcaaagtgt cagctttggc aggtccttct tctgatgatg
     2101 agaacgaaga ggaatcaaaa ccagaaaagg aagacgaacc acaggaagat gctaaggaat
     2161 tgcagcaagg taaaccgtat cattggagag actggtcaat aattagagga agggactgct
     2221 tatatatttg gagtgatgct gcagctttgg aattatctaa tggcagtaat ggatggttca
     2281 gatttatctt ggatggaaaa cttgctacca tgtattcaag tggtagtcct gaaggtggat
     2341 cggatagttc agaaagcaga agtgaattct tagagaagtt acaaagagcc cggggccaag
     2401 taaagccatc tacttcaagt caacctatac tgtcagcacc gggacccacg aaactgactg
     2461 tagggaactg gtcattaaca tgcttgaaag aaggagaaat tgctattcat aactcagatg
     2521 gtcagcaagc tacaatacta aaagaagatt tgcctggttt tgtatttgaa tctaatagag
     2581 gaacgaaaca ttcgtttact gcagaaacat ctctgggttc agagtttgtg actggctgga
     2641 ctggcaaaag aggcagaaaa ctcaaatcca agttggagaa aacaaagcaa aaggtacgaa
     2701 ctatggctcg agacttgtat gacgaccact ttaaagctgt tgaaagcatg cctcgtgggg
     2761 tggtagtgac actcagaaat atagcaactc agctggagtc atcttgggaa ctccatacga
     2821 atagacaatg tatcgaaggt gaaaacactt ggcgagactt aatgaagaca gccttagaaa
     2881 acctaattgt actgctgaag gatgagaaca cgatctcacc gtatgaaatg tgtagtagtg
     2941 gtttagtcca ggcacttctt actgttctaa acaatagtat agatttggat atgaagcaag
     3001 attgtagtca actggtagaa agaataaatg tcttcaaaac agcctttagt gaaagtgaag
     3061 atgatgagag cagaccagca gttgcattaa ttcgaaaatt aatagctgta ctagaatcaa
     3121 ttgaacgcct acctctccat ttgtatgaca caccaggatc cacgtataac ctccagatac
     3181 ttacaagaag attacgcttt cggttggaac gtgcacctgg tgaaacttca ttaatagacc
     3241 ggacaggcag gatgctgaag atggagccct tagctacagt tgaatctctg gaacagtatc
     3301 tgctgaaaat ggtggcaaag cagtggtacg actttgacag atcctcattt gtttttgttc
     3361 gaaaattaag agaaggccaa aattttatat tccggcacca acatgacttt gatgagaatg
     3421 gaatcattta ctggattgga acaaatgcaa aaactgcgta tgaatgggta aatcctgcag
     3481 cttatggact cgtagtcgtc acatcatcag aaggaaggaa tctgccctat ggccgcttgg
     3541 aggacatact aagtcgagat aattcagctt taaattgtca cagcaatgat gataaaaatg
     3601 cctggtttgc catagatctg ggtgtctggg taataccttc agcatacaca cttcgtcatg
     3661 ctcgtggcta tggaaggtct gcactgagaa attgggtttt ccaggtatcc aaagatggac
     3721 agaactggac ttctttgtat acccatgttg atgactgcag tctcaatgaa ccagggtcaa
     3781 ctgcaacatg gccccttgac ccagcgaagg atgaaaagca agggtggcgg catgtcaggc
     3841 tgaagcagat ggggaagaac gccagtggac agacgcacta cctctcgctc tccggctttg
     3901 aactctatgg cactgtgaat ggcgtgtgcg aagaccaact agggaaagca gctaaagaag
     3961 cagaagctaa tcttagaagg cagaggcgcc tggtgcgctc tcaggtcctc aagtacatgg
     4021 ttccaggagc acgtgttatc aggggccttg attggaagtg gcgagatcag gatggcagcc
     4081 cgcagggaga aggcacagtc acaggcgagc tccacaatgg ctggattgat gtcacctggg
     4141 atgctggtgg ctcaaactct taccgtatgg gcgcagaagg aaaatttgac ctcaagcttg
     4201 caccagggta cgaccctgat acagtggcat cacccaaacc tgtttcatcc actgtttcag
     4261 gcacaacgca atcatggagc agcttggtga aaaacaactg tccagacaag acgtctgctg
     4321 ctgcaggctc ctcaagtaga aaagggagca gcagctctgt gtgtagcgtg gccagtagca
     4381 gcgacatcag cttggcttcg accaaaacgg aacggagatc agaaattgta atggaacaca
     4441 gtatagtttc aggagctgat gtccatgaac caattgttgt tctttcatct gctgaaaacg
     4501 tccctcaaac agaagtaggg tcatcttcca gtgcaagcac cagcacccta acagcggaaa
     4561 cgggaagtga aaatgcggaa aggaagttag gccctgatag ttctgttcga gctcctgggg
     4621 agtctagtgc gatatccatg gggattgtta gcgttagctc tcctgatgtt agttcggtat
     4681 ctgaattaac caataaggaa gcagcttcac aacgacccct tagctcttcg gcaagtaaca
     4741 gactgtcggt gagctctctg ttggcagccg gggcccctat gagctccagt gcgagtgtac
     4801 ctaacctgtc ctcaagagag acatctagct tggagagctt tgtcaggaga gtggcaaaca
     4861 tagcacggac taatgccacc aacaacatga acctaagccg aagcagcagt gacaacaaca
     4921 ctaacacttt ggggaggaac gtgatgagca ccgcaacttc tccacttatg ggtgctcaga
     4981 gtttccctaa tttgaccaca cctggtacta catcaacagt gacaatgtca acatcgagtg
     5041 ttacgagcag cagcaatgta gctacggcaa ccacagtttt atcagtgggt caatcattaa
     5101 gtaatacttt aaccaccagc ctcacatcaa cctctagtga gagtgacaca ggccaggaag
     5161 cagaatactc cttatatgat ttcctcgaca gctgccgtgc cagtactctc ttagctgaac
     5221 tagatgatga cgaggatttg cctgagcctg acgaggaaga cgatgagaat gaagatgaca
     5281 atcaggagga ccaagaatac gaggaggtta tgattctgag acgtccctcc ctgcaacgcc
     5341 gagctggctc tcgctctgac gtaacacacc atgtcgtcac ctcccagctc ccacaggtcc
     5401 cttctggagc agggagccgg cctgttgggg aacaggaaga agaagagtat gaaaccaaag
     5461 gaggccgccg cagagcctgg gatgacgact atgtgctaaa gcgccagttt tctgcactgg
     5521 tccctgcttt tgatcctaga cctggtcgta ccaatgtcca gcagacaact gacctagaaa
     5581 ttcctccccc aggaacacct cactcagagc tcttggagga agttgaatgt actccgtcac
     5641 ctcgcttggc tctcacactg aaagtgacgg ggcttggaac aacgcgggaa gttgaactgc
     5701 cacttaccaa tttcagatcc accatctttt actatgtaca aaaactgctt caactgtctt
     5761 gtaatggcaa tgtgaagtca gataaactta ggcgtatttg ggagcccact tacacaatca
     5821 tgtatagaga aatgaaggat tctgataaag aaaaggaaaa tgggaaaatg ggttgctggt
     5881 ctatagagca tgtggaacag taccttggca ctgacgaatt accaaagaat gacttgataa
     5941 cctacctgca gaagaatgca gatgccgctt tcctgcgcca ctggaaatta actggcacta
     6001 ataaaagtat taggaaaaac agaaattgtt ctcagcttat agctgcatat aaggattttt
     6061 gtgagcatgg aacaaagtct ggattaaacc agggggctat ttctagtctt caaagtagtg
     6121 atattcttaa tttgacaaaa gagcagcctc aggctaaagc aggcaacggg cagagcccct
     6181 gtggagtaga ggacgtcctt cagcttctgc ggattctgta tatagttgca agtgatcctt
     6241 attcaaggat atcccaagaa gatggcgatg agcagcctca gtttactttt ccacctgatg
     6301 aatttacaag taaaaaaatc accacaaaaa ttttgcagca gattgaggaa ccgttggcac
     6361 tggccagtgg ggctctgcca gactggtgtg aacagttaac cagcaagtgt cctttcctga
     6421 tcccattcga gacgaggcag ctttatttca cctgtactgc atttggtgcg tccagagcaa
     6481 tagtgtggct acagaacagg cgggaagcca ctgtggagcg aactcggacc acgagcagtg
     6541 tacggcgaga tgatcctggg gaatttagag tgggtcgcct caagcacgaa agagtgaaag
     6601 ttccccgtgg agagtctctg atggagtggg ccgagaatgt catgcagata cacgcagatc
     6661 ggaagtcagt tctcgaggtt gaatttctag gagaagaagg aactggcttg ggacccactt
     6721 tagagtttta tgctcttgtg gcggctgagt ttcagaggac tgacttgggg acttggcttt
     6781 gtgatgataa ttttccagat gatgaatctc gtcatgttga tcttggaggt ggattgaagc
     6841 ctccaggata ctatgtacag cggtcatgtg gactgttcac agcgccattc ccacaggaca
     6901 gtgatgagct tgaaaggatc acaaaactct tccatttcct tgggattttc ttggccaaat
     6961 gtattcagga caatagactg gtggacttgc ctatctctaa gcctttcttt aaacttatgt
     7021 gcatgggcga cattaaaagc aatatgagca aactaatcta tgagtcccgc ggcgacagag
     7081 acttgcactg tactgaaagt cagtcggaag cttctacaga agaaggccat gactccctct
     7141 cagtgggaag ctttgaagag gattcaaaat cagaatttat cctcgatccc cctaagccca
     7201 aacccccagc ctggtttaat gggattttaa cttgggaaga ttttgaacta gtaaatcctc
     7261 acagagccag atttttaaaa gaaattaaag accttgctat taagaggcgc cagattctag
     7321 gcaataaaag tctttctgaa gatgagaaga acacaaagtt acaggaactc gtgctcagga
     7381 atccatcagg ctcgggacct ccactgagca tcgaggactt aggtttaaat ttccagtttt
     7441 gcccatcttc aagaatatat ggctttacag ctgtggatct caagccaagt ggggaagatg
     7501 agatgataac aatggataat gcagaagaat atgtggattt gatgtttgac ttctgtatgc
     7561 atacgggtat tcagaaacag atggaagctt ttcgagatgg gtttaataaa gtttttccaa
     7621 tggagaaatt aagttccttc agccatgagg aagtccagat gattctttgt ggaaatcagt
     7681 caccatcctg ggcagcagag gacattatca attacacgga acctaagctt ggctatacac
     7741 gtgacagtcc tggcttcctg cggtttgtga gggttttatg tggcatgtcc tcagatgaaa
     7801 ggaaagcatt cctgcagttt accactggct gttcaactct gcccccaggt ggactggcta
     7861 acctgcatcc gaggctcaca gttgtacgaa aggttgatgc tactgatgcg agctatccat
     7921 cggtcaacac ctgtgtccac tatcttaagt tacctgagta ttcttctgag gagatcatga
     7981 gagagcgctt gctagctgct acaatggaga aaggctttca tctcaattga gtcttgaaat
     8041 gcagaagaga cagagtctgg gtgaagcctc ttgtgtttgt gtgaagagaa gtgtatgatt
     8101 ctccacaata atgacacttg ccttgttttc caccattaag gcttcgagaa cacgtggaat
     8161 aagttcctta gctgctaatg acaaaacaaa ccctttaact acccagccag caggtatcca
     8221 gcacaggaca ctgtgttgct ttacaagggc tcacgtgact ggaaaaggtg gctctaccta
     8281 actgttccac agggcagcct ctcagatcat cagtgctcac tgtaaatgga accgtgtttg
     8341 tatcaagttt gtcatcgttt catacttcat acactacagt tgccatcact gacccccatt
     8401 ttgctggctt ttttagctac ttggtcaaaa atactgcttc cttaaaacat agagtgttag
     8461 tgagcatctc cagccgtttc ttttcctctt taatgacaga cacctgcact accagagtgt
     8521 cccgtgctct ctgtctgtcc cgcacataat catgcacacc cttgtcattt ctttaaggtg
     8581 ggagtatatt ttttttttca taaataccat tctataaaga tgaaattcta aagtgtgttt
     8641 gtgcagctca aaataaagat atattaaggg aggggcagac actggcctag gtgcaaggca
     8701 cactcacagc gacttttatg tttggttgta ttttctttgt atattataaa catttattta
     8761 acttgttgca gtttgaagta aatttctgaa atgtatgctc aacaataatc attaaaatgt
     8821 ttgcagcgta
//
