LOCUS       NM_001301364            6282 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus high density lipoprotein (HDL) binding protein
            (Hdlbp), transcript variant 2, mRNA.
ACCESSION   NM_001301364 XM_006529073
VERSION     NM_001301364.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6282)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6282)
  AUTHORS   Zinnall,U., Milek,M., Minia,I., Vieira-Vieira,C.H., Muller,S.,
            Mastrobuoni,G., Hazapis,O.G., Del Giudice,S., Schwefel,D., Bley,N.,
            Voigt,F., Chao,J.A., Kempa,S., Huttelmaier,S., Selbach,M. and
            Landthaler,M.
  TITLE     HDLBP binds ER-targeted mRNAs by multivalent interactions to
            promote protein synthesis of transmembrane and secreted proteins
  JOURNAL   Nat Commun 13 (1), 2727 (2022)
   PUBMED   35585045
  REMARK    GeneRIF: HDLBP binds ER-targeted mRNAs by multivalent interactions
            to promote protein synthesis of transmembrane and secreted
            proteins.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6282)
  AUTHORS   Begg,D.P., Steinbrecher,K.A., Mul,J.D., Chambers,A.P., Kohli,R.,
            Haller,A., Cohen,M.B., Woods,S.C. and Seeley,R.J.
  TITLE     Effect of guanylate cyclase-C activity on energy and glucose
            homeostasis
  JOURNAL   Diabetes 63 (11), 3798-3804 (2014)
   PUBMED   24898144
REFERENCE   4  (bases 1 to 6282)
  AUTHORS   Combes,A.N., Lesieur,E., Harley,V.R., Sinclair,A.H., Little,M.H.,
            Wilhelm,D. and Koopman,P.
  TITLE     Three-dimensional visualization of testis cord morphogenesis, a
            novel tubulogenic mechanism in development
  JOURNAL   Dev Dyn 238 (5), 1033-1041 (2009)
   PUBMED   19334288
REFERENCE   5  (bases 1 to 6282)
  AUTHORS   McKee,A.E., Minet,E., Stern,C., Riahi,S., Stiles,C.D. and
            Silver,P.A.
  TITLE     A genome-wide in situ hybridization map of RNA-binding proteins
            reveals anatomically restricted expression in the developing mouse
            brain
  JOURNAL   BMC Dev Biol 5, 14 (2005)
   PUBMED   16033648
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6282)
  AUTHORS   Rohwedel,J., Kugler,S., Engebrecht,T., Purschke,W., Muller,P.K. and
            Kruse,C.
  TITLE     Evidence for posttranscriptional regulation of the multi K homology
            domain protein vigilin by a small peptide encoded in the 5' leader
            sequence
  JOURNAL   Cell Mol Life Sci 60 (8), 1705-1715 (2003)
   PUBMED   14504658
REFERENCE   7  (bases 1 to 6282)
  AUTHORS   Welch,C.L., Xia,Y.R., Hong,H., Stallcup,M.R. and Lusis,A.J.
  TITLE     Localization of the mouse glucocorticoid receptor-interacting
            protein 1 gene (Grip1) to proximal chromosome 1 by linkage analysis
  JOURNAL   Mamm Genome 8 (8), 620-621 (1997)
   PUBMED   9250876
REFERENCE   8  (bases 1 to 6282)
  AUTHORS   Welch,C.L., Xia,Y.R., Shechter,I., Farese,R., Mehrabian,M.,
            Mehdizadeh,S., Warden,C.H. and Lusis,A.J.
  TITLE     Genetic regulation of cholesterol homeostasis: chromosomal
            organization of candidate genes
  JOURNAL   J Lipid Res 37 (7), 1406-1421 (1996)
   PUBMED   8827514
  REMARK    Erratum:[J Lipid Res 1996 Oct;37(10):2269]
REFERENCE   9  (bases 1 to 6282)
  AUTHORS   Spur,N.K., Bashir,R., Bushby,K., Cox,A., Cox,S., Hilde Brandt,F.,
            Hill,N., Kao,F.T., Krols,L., Marzella,R., Miller,N., Nothwang,H.G.,
            Rocchi,M., Sarfarazi,M., Stratakis,C.A., Wallgren-Petterson,C. and
            Naylor,S.
  TITLE     Report and abstracts of the Fourth International Workshop on Human
            Chromosome 2 Mapping 1996
  JOURNAL   Cytogenet Cell Genet 73 (4), 255-273 (1996)
   PUBMED   8751373
REFERENCE   10 (bases 1 to 6282)
  AUTHORS   LeBoeuf,R.C., Xia,Y.R., Oram,J.F. and Lusis,A.J.
  TITLE     Mapping of the gene for high-density lipoprotein binding protein
            (Hdlbp) to proximal mouse chromosome 1
  JOURNAL   Genomics 23 (1), 296-298 (1994)
   PUBMED   7829095
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB854571.1, AK161663.1, AK132355.1, AC108412.8 and CK638858.1.
            
            [WARNING] On Aug 5, 2024 this sequence was replaced by
            NM_001301364.2.
            
            On Aug 13, 2014 this sequence version replaced XM_006529073.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK153965.1, AK132355.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-49                BB854571.1         2-50
            50-2407             AK161663.1         2-2359
            2408-4438           AK132355.1         2394-4424
            4439-5613           AC108412.8         50849-52023         c
            5614-6282           CK638858.1         23-691
FEATURES             Location/Qualifiers
     source          1..6282
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="1"
                     /map="1 47.24 cM"
     gene            1..6282
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /note="high density lipoprotein (HDL) binding protein"
                     /db_xref="GeneID:110611"
                     /db_xref="MGI:MGI:99256"
     exon            1..122
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            123..187
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            188..300
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     CDS             225..4031
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /note="HDL-binding protein; high density
                     lipoprotein-binding protein"
                     /codon_start=1
                     /product="vigilin"
                     /protein_id="NP_001288293.1"
                     /db_xref="CCDS:CCDS15189.1"
                     /db_xref="GeneID:110611"
                     /db_xref="MGI:MGI:99256"
                     /translation="MSSVAVLTQESFAEHRSGLVPQQIKVATLNSEEENDPPTYKDAF
                     PPLPEKAACLESAQEPAGAWSNKIRPIKASVITQVFHVPLEERKYKDMNQFGEGEQAK
                     ICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVPIPKE
                     HHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAE
                     QDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQ
                     LAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPS
                     DSISETVILRGEPEKLGQALTEVYAKANSFTVSSVSAPSWLHRFIIGKKGQNLAKITQ
                     QMPKVHIEFTEGEDKITLEGPTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHRHL
                     IGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENER
                     TKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKC
                     TKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNS
                     ETIIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEE
                     CGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHK
                     FLIGKGGGKIRKVRDSTGARIIFPAAEDKDQDLITIIGKEDAVREAQKELEALIQNLE
                     NVVEDYMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCV
                     EAAKKRIQEIIEDLEAQVTVECAIPQKFHRSVMGPKGSRIQQITRDYNVQIKFPDREE
                     NPVHSVEPSIQENGDEAGEGREAKETDPGSPRRCDIIIISGRKEKCEAAKEALEALVP
                     VTIEVEVPFDLHRYIIGQKGSGIRKMMDEFEVNIHVPAPELQSDTIAITGLAANLDRA
                     KAGLLDRVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHEVNIQF
                     PDKDDGNQPQDQITITGYEKNTEAARDAILKIVGELEQMVSEDVPLDHRVHARIIGAR
                     GKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLADVVDS
                     EALQVYMKPPAHEESRAPSKGFVVRDAPWTSNSSEKAPDMSSSEEFPSFGAQVAPKTL
                     PWGPKR"
     exon            301..458
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            459..674
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            675..881
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            882..1097
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            1098..1304
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            1305..1412
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            1413..1517
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            1518..1596
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            1597..1736
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            1737..1841
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            1842..1955
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            1956..2042
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            2043..2174
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            2175..2393
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            2394..2615
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            2616..2834
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            2835..2973
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            2974..3128
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            3129..3233
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            3234..3368
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            3369..3512
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            3513..3698
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            3699..3815
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            3816..3944
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     exon            3945..6264
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4411..4416
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /note="hexamer: AATAAA"
     polyA_site      4442
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /note="major polyA site"
     regulatory      6246..6251
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /note="hexamer: AATAAA"
     polyA_site      6264
                     /gene="Hdlbp"
                     /gene_synonym="1110005P14Rik; D1Ertd101e"
                     /note="major polyA site"
ORIGIN      
        1 gggattggag cctccgccct atatagcagc ggcggcccgg gcgccgcgcc tcggagcgtc
       61 ccggcttctc ccgcgcagcg gcagcgacag acggacagac tctcgggtgg tcacactcac
      121 gataaaagct ggcaggctga cagaggcaac ctcaggacgg actttctggc tactgaccat
      181 tttgctgtgt cttactagga tcgtgtgtgg acgtgagatc aaccatgagc tccgttgcag
      241 ttttgaccca agagagtttt gctgaacatc gaagtgggct ggttccacaa caaatcaaag
      301 ttgccacctt aaattcagaa gaggaaaatg accctccaac ctacaaggat gccttccctc
      361 cacttcctga gaaagcagct tgcttggaga gtgcccaaga acctgccgga gcctggagta
      421 acaagatccg gcccatcaag gcctctgtca tcactcaggt gtttcatgta cccctggaag
      481 agagaaaata taaggacatg aaccagtttg gagagggtga acaagcaaaa atctgccttg
      541 agatcatgca gaggactggt gctcacctgg aactctctct ggctaaagat caaggtctct
      601 ccatcatggt ctcagggaag ctggatgccg tcatgaaagc ccgcaaagac attgttgcta
      661 gactacagac acaggcctca gcaactgttc ccattcctaa agagcaccat cgctttgtta
      721 ttggcaaaaa cggagagaaa ctgcaagact tagaactaaa aactgcaacc aaaatccaga
      781 tcccacgccc agatgacccc agtaatcaga tcaagatcac tggcaccaaa gaaggcatcg
      841 agaaagctcg ccatgaagtc ctcctaatct ctgctgagca ggacaagcgt gctgtagaga
      901 ggctagaagt ggagaaggct ttccacccct tcatcgctgg gccgtacaac agacttgtgg
      961 gtgaaatcat gcaggagaca gggacgcgaa tcaacatccc tccacccagt gttaaccgta
     1021 cagaaatcgt cttcactgga gagaaggagc agctggctca ggctgtggct cgcattaaga
     1081 agatttatga ggaaaagaag aagaagacta caaccattgc ggtagaggtg aagaagtctc
     1141 agcacaagta tgttattggg ccaaagggca attcactgca agaaatcctg gaaagaactg
     1201 gagtttctgt tgagatccca ccctccgaca gcatctctga gactgtgata cttagaggcg
     1261 aacctgaaaa gttgggacag gcgttgactg aagtctatgc caaggccaac agttttacag
     1321 tctcctcagt ctctgcccct tcctggcttc atcgtttcat cattggtaag aaagggcaga
     1381 acctggccaa aatcactcag caaatgccaa aggttcacat tgagttcaca gaaggtgagg
     1441 acaagatcac cctggagggc cccacagagg atgtgaatgt agcccaagaa cagattgaag
     1501 gaatggtcaa agacctgatt aataggatgg actatgtaga gatcaacatt gaccataaat
     1561 tccacagaca cctcattgga aagagcggag ccaacatcaa cagaatcaaa gaccagtaca
     1621 aagtgtctgt gcgcatcccc cctgacagtg aaaagagtaa cctgatccga attgagggag
     1681 acccacaggg tgttcagcag gccaagcggg agctgctgga gcttgcttct cgcatggaaa
     1741 atgagcgcac caaggatcta atcatcgagc aaagatttca tcgcacaatc attgggcaga
     1801 aaggtgaacg gattcgagaa attcgtgaca aattcccaga ggttatcatc aactttccag
     1861 acccagcaca aaaaagtgat attgtacaac tcagaggccc caagaatgag gtggagaagt
     1921 gcactaagta tatgcagaag atggtcgcag acctggtgga aaatagctat tcaatttctg
     1981 taccaatctt caaacagttt cacaagaata tcatcgggaa aggaggcgca aacattaaaa
     2041 agatccgtga agagagcaac accaagattg accttcctgc agagaacagc aactctgaga
     2101 ccattattat cactggcaag cgagccaact gtgaagctgc ccgcagccgg attctgtcta
     2161 tccagaaaga tctggccaac atagctgaag tggaggtctc aattcctgcc aaactacaca
     2221 actctctcat tggcacaaag ggccgtctga tccgctccat catggaggaa tgtggtggcg
     2281 tccatattca ctttcctgtg gaaggttctg gaagcgacac tgttgtcatc aggggtcctt
     2341 cctcagatgt agagaaggcc aagaagcagc tcctgcacct ggctgaggag aagcaaacca
     2401 agagttttac tgtggacatc cgagccaagc cagaatacca caaattcctc attggcaaag
     2461 ggggaggtaa aatccgaaag gtgcgtgaca gtactggagc ccgcatcata tttccggctg
     2521 ctgaagataa ggaccaggac ctgatcacaa tcataggaaa ggaggatgct gtccgtgagg
     2581 cccaaaagga gctggaagca ttgatccaga acctggagaa tgtggttgaa gactatatgc
     2641 tggtggaccc caaacaccac cgccattttg tcatccgaag aggacaagtt ttacgagaaa
     2701 ttgctgaaga gtatggcggg gtgatggtca gcttcccacg ctctggcacg cagagtgata
     2761 aagtcactct caagggtgcc aaggactgtg tggaggcagc caagaaacgc attcaggaaa
     2821 tcattgagga tctggaagct caagtgacag tggaatgtgc tataccccag aagtttcacc
     2881 gatcggtcat gggtcccaaa ggttcaagaa tccagcagat cactcgggac tacaatgttc
     2941 aaatcaagtt cccagataga gaggaaaatc cagttcacag tgtagagcct tccatccagg
     3001 agaatggaga tgaggctgga gagggcagag aggccaagga gaccgaccct ggctctccca
     3061 ggaggtgtga catcataatc atctctggcc ggaaagagaa atgcgaggct gccaaggaag
     3121 ccctggaggc actggttcca gtcaccatcg aggtagaggt accctttgat cttcaccgct
     3181 acatcattgg gcaaaaagga agtggaatcc gcaagatgat ggatgagttt gaggtgaaca
     3241 tccatgtacc agcccccgag ctgcagtcag acaccatcgc catcactggc cttgcagcaa
     3301 atttggacag ggctaaggcg gggctactgg atcgagtaaa ggagctgcag gctgagcagg
     3361 aagatcgggc tttaaggagt tttaagctga gtgtcactgt agaccccaaa taccatccca
     3421 aaattatcgg gagaaaagga gcagtgatca cccagatccg cttggaacat gaagtgaaca
     3481 tccaatttcc tgataaggat gatgggaacc agccccagga ccaaatcacc atcacagggt
     3541 atgagaagaa cactgaagct gcccgtgatg ctatcctgaa aattgtgggt gagcttgagc
     3601 agatggtttc tgaggatgtt ccactggatc accgtgtgca cgctcgaatc attggtgccc
     3661 ggggcaaagc catccggaaa ataatggatg aattcaaggt ggacattcgc ttcccacaga
     3721 gtggagcgcc agaccccaat tgcgtcactg tgacaggact cccagagaat gtggaggaag
     3781 ctatcgacca tatcctcaac ctagaagagg aatatctggc agatgtggtg gacagtgagg
     3841 cactgcaagt ttacatgaag cccccagcac atgaagagtc cagggcacca tccaaaggct
     3901 ttgtggtgcg agatgctccc tggacctcca acagcagtga gaaggctcct gatatgagca
     3961 gctctgaaga atttcccagc tttggggctc aagtggcccc caagaccctc ccttggggcc
     4021 ccaaacgata atgatcaaaa agaaaccttt ccagcctgct gcccaaaccc aaccacacaa
     4081 tggtttgtct caatctgacc cagcagctgg accctcgtaa attgttgatg ctctttcccc
     4141 tccccgaggt ctcgcagcaa agcctggtgg gctggccttg tgtggctgct tctccaggcc
     4201 tggtcagcac ccagcaggct cagggtctgc tcctgatgct gtgctctggg acaggcacgc
     4261 cactgtgtga aacactaagc aaggtaatcg agcatttcgt gatcacagac tccagcttcc
     4321 tggtccaccc agcatgtagt cagcactctg accttcacac cagagctcca cagcggctag
     4381 gagttgactt cctgtgtcat gacctcagga aataaatttc cttgacttta taaaagccaa
     4441 aacgtttgcc ctcttccttt cccacctccc tcctgcccac cacctgtcgc ccagaccttc
     4501 ctctgttgaa agcagtcagc ttcctttagc tgtcaaaatc tgcttagcac aggcttcagg
     4561 ataggaggaa ggcatggtat cggacagcaa gaggtcagat gtcctggtga tagagtgggc
     4621 tgagaagtag agggtggcct gggtcctcag atagtgctga ccgtgcccac tttgggttcc
     4681 gaaagcatca ggggcttcta ttgcagcttt agcctcatga tcctatgtat cttagaggca
     4741 cagctgtgtg tattccactt gggttccctg tgactatcac agtggactag ggtggcttga
     4801 gactttgggg gaaaggggag gtagagactg gcttttcttt tggtgatggg gagggggctc
     4861 aaccctaagt gacagctcag ctttcccacg acctttagcc tctgcctgcc ttgttcagtt
     4921 gccttctttc tacctcagcc agtgtggtag tactctcatg tgggttagtg ccacccaagg
     4981 ctcttcttgt gatgtagaca tttctggtga ttctgggctt gccattgagt tgagggtgga
     5041 ggccagtgct ttccctcagt ccacatgatt cagggactgg gccagagctg ggtgttcctt
     5101 cccagccagc ctgaccatgc aggctctggc aagcataacc tggatgcttt atgcagtcct
     5161 aaggaacagg cttaaggggc aggtctcgtc gatagaggtg gtcatttagg gtggattcac
     5221 agggaaggca gaatgaaaac aacccaaagc agggagcaca gctatctgaa ggagatcttt
     5281 tcctcaggta caagaggtaa tttttggacc actggcctcc agctagcttg gctgtaggcc
     5341 aaccctcacc aagaaaagtg gtcccgagca gacaaacccc tgtcaggctg tggaaactga
     5401 ggacagacct tttatctcca ggtcatctga tcaactagca acatgtcccc tcccagatac
     5461 ttgggttact agaaaagcca acttgtggcg atctcatggc cttccctggg aactgtcact
     5521 tctactatga tacctttccc cctcaagtct ttgactcccc catttaataa ctcaggcttg
     5581 gctacctgta gactctaatc ctaagtggat ccagaattgc tttcccaagt ctaacttcag
     5641 ttccctttgg atggaaccag tcccacatgt acccacttag aagaacgata ctgagatggg
     5701 aaaagaacat ctactttgtt cagtaggctg gcagcttaag ccaggtgggt gagacgggga
     5761 gagcgcttcc ctgcctttcc ctggagccgt ctcttctccc atctgcatga gactggggac
     5821 accttgcttc cctccttccc ttccagcccc ctcttcatct tcattgtcat cctacaacat
     5881 ccagtctccc ctcactgaag gtaaagttta aattatcacc aggattttgc acatctcctt
     5941 ttattgctaa gtgctgtaga tgtaagccct atcctaagct gttcagggtc tcactccttt
     6001 tctctgattg ttaataagga ctatgaaatt gactgtaccc aggtcacctc tctgcagcct
     6061 ccaagatgtt gaggagccta gggcaggggt gggagtgtct tttcctcctt gttgaatgtc
     6121 ttccatgtcc tatgtttcca tagctacatc catcccttgg ccttaacttt ggaatttgga
     6181 gattatatgc aaacatgtgt aaaggctcat gaatatggat gacactggaa ttttataaat
     6241 tctaaaataa aacccaaaac cagaaaaaaa aaaaaaaaaa aa
//
