LOCUS       NM_029826               2318 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus haloacid dehalogenase-like hydrolase domain containing
            2 (Hdhd2), transcript variant 1, mRNA.
ACCESSION   NM_029826
VERSION     NM_029826.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2318)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2318)
  AUTHORS   Wang,B., Harrison,W., Overbeek,P.A. and Zheng,H.
  TITLE     Transposon mutagenesis with coat color genotyping identifies an
            essential role for Skor2 in sonic hedgehog signaling and cerebellum
            development
  JOURNAL   Development 138 (20), 4487-4497 (2011)
   PUBMED   21937600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY069367.1, AK137285.1 and AC132608.2.
            
            On Jan 28, 2006 this sequence version replaced NM_029826.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660817.19068.1,
                                           SRR1660813.84843.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                BY069367.1         11-21
            12-1596             AK137285.1         4-1588
            1597-2318           AC132608.2         84181-84902
FEATURES             Location/Qualifiers
     source          1..2318
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="18"
                     /map="18 51.98 cM"
     gene            1..2318
                     /gene="Hdhd2"
                     /gene_synonym="0610039H12Rik; 3110052N05Rik"
                     /note="haloacid dehalogenase-like hydrolase domain
                     containing 2"
                     /db_xref="GeneID:76987"
                     /db_xref="MGI:MGI:1924237"
     exon            1..71
                     /gene="Hdhd2"
                     /gene_synonym="0610039H12Rik; 3110052N05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            72..182
                     /gene="Hdhd2"
                     /gene_synonym="0610039H12Rik; 3110052N05Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             82..861
                     /gene="Hdhd2"
                     /gene_synonym="0610039H12Rik; 3110052N05Rik"
                     /note="isoform 1 is encoded by transcript variant 1;
                     haloacid dehalogenase-like hydrolase domain-containing
                     protein 2"
                     /codon_start=1
                     /product="haloacid dehalogenase-like hydrolase
                     domain-containing protein 2 isoform 1"
                     /protein_id="NP_084102.1"
                     /db_xref="CCDS:CCDS37863.1"
                     /db_xref="GeneID:76987"
                     /db_xref="MGI:MGI:1924237"
                     /translation="MAARRALKAVLVDLNGTLHIEDAAVPGAQEALKRLRATSVMVRF
                     VTNTTKESKKDLLERLKKLEFEISEDEIFTSLTAARNLIEQKQVRPMLLVDDRALPEF
                     TGVQTQDPNAVVIGLAPEHFHYQLLNQAFRLLLDGAPLIAIHKARYYKRKDGLALGPG
                     PFVTALEYATDTKAMVVGKPEKTFFLEALRDADCAPEEAVMIGDDCRDDVDGAQNIGM
                     LGILVKTGKYKAADEEKINPPPYLTCESFPHAVDHILQHLL"
     exon            183..391
                     /gene="Hdhd2"
                     /gene_synonym="0610039H12Rik; 3110052N05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            392..476
                     /gene="Hdhd2"
                     /gene_synonym="0610039H12Rik; 3110052N05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            477..693
                     /gene="Hdhd2"
                     /gene_synonym="0610039H12Rik; 3110052N05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            694..757
                     /gene="Hdhd2"
                     /gene_synonym="0610039H12Rik; 3110052N05Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            758..2318
                     /gene="Hdhd2"
                     /gene_synonym="0610039H12Rik; 3110052N05Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1528..1533
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hdhd2"
                     /gene_synonym="0610039H12Rik; 3110052N05Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      1548
                     /gene="Hdhd2"
                     /gene_synonym="0610039H12Rik; 3110052N05Rik"
                     /note="major polyA site"
     polyA_site      1600
                     /gene="Hdhd2"
                     /gene_synonym="0610039H12Rik; 3110052N05Rik"
     polyA_site      1779
                     /gene="Hdhd2"
                     /gene_synonym="0610039H12Rik; 3110052N05Rik"
     polyA_site      1800
                     /gene="Hdhd2"
                     /gene_synonym="0610039H12Rik; 3110052N05Rik"
ORIGIN      
        1 cgactgcatc cgggttggaa ggcgtgctcg gcggcgctcg ggcctttcca gaggacagcg
       61 gggctgcgag gggcatgaag gatggcagcg cgccgtgcgt taaaagctgt tttggtggat
      121 ctcaatggca cacttcacat tgaagatgca gctgtgccag gcgcacagga agctcttaaa
      181 aggttgcgtg ccacttctgt gatggttcgg tttgtgacca atacaaccaa agagagcaag
      241 aaagacctac tggagagact gaaaaaactg gagtttgaga tctccgaaga tgaaatattt
      301 acttccctga cagcagcccg aaacttaatc gagcagaagc aagtcaggcc catgctcctg
      361 gttgatgacc gcgcactgcc tgagttcaca ggagttcaaa cccaggaccc caacgctgtg
      421 gtcattggac tggcaccaga gcattttcat tatcagcttc tgaaccaagc attccggcta
      481 ctcctggatg gagcccctct gatagctatc cacaaggcca ggtactacaa gagaaaagat
      541 ggcttagcct tgggaccagg accatttgtg actgccttag agtatgccac agacacgaaa
      601 gccatggtgg tggggaaacc agagaagaca ttctttctgg aagccttgag ggatgctgac
      661 tgtgcaccgg aggaggccgt catgatagga gacgattgca gggatgatgt cgatggggct
      721 cagaacattg gcatgctggg catcttagtt aaaaccggga aatacaaagc agcagatgaa
      781 gaaaaaatta atccacctcc ctacttaact tgcgagagct tccctcacgc tgtggaccac
      841 attctgcagc acctcctgtg aaccagcatg tgttgtctgg actggatgga tccctaacaa
      901 ggtggcatca gtaggctgcg ccatccagtg ctgatcctat ttaacccttt cattgtgcat
      961 taattagaaa gagggggatt ggattgcagc caaccctaaa ccttgctaat ctcttttgtt
     1021 ttataaaaga agatgggacc tgaagaaagg gagagctgag attttgtgcc attcctgtta
     1081 aaatattcat caggttcact gggctggagg agaagctcct gtgggcgcag aggagcagta
     1141 gctctccact cctccgtggt ggaagtgaga ggatcctctg tgagcatgac tgactcacac
     1201 agagatgcac tggaaggtgc attaggctgt cagcaagatg ccagagttga gccgtgaagc
     1261 tctgcagaca agccacagag aagcaagcta gcagcagtgt ggcgagccct tcagctgaga
     1321 tccagtgaag ttgctttaac agatgtggaa agccagatct tccactgtat tcccagcgca
     1381 gatgactttt tttctgttca ttagccagag atgactaatt taaatttaga acccgaattt
     1441 aatttaaaat aatatttcca ttaataacct attcattgca gatacctatt atactgtgta
     1501 acagttgttt tggaaatttt atgtaaaatt aaaactatca gtattttaca gatgttttaa
     1561 ttagacattg ttattaacag gaacagtgca gaaaccaaaa tcaagccttt aatgtcttat
     1621 agaccgtgca tttctgaagt tagtgtcccc cggggaccta ttaactgtgc atttgcaaga
     1681 tttcattatt tttgcctctg acactatggg agaaatcttt taggaactat tgggacagat
     1741 tcaggctttt atgtacttct tactacagtt gtaaaatgag atctcgtctc ggtgcctgga
     1801 tgattcttct catgttatac ccacccagat gaaggagatg aagtagggaa tggctttcct
     1861 gctgcatttg catgctgtgc caatcctcgg ccgtggcagt tgttttacgg ggctcttggg
     1921 cactgaatta ttaggataga atcgtgcatc atcacagtgc tcaccttatt gaggcgcaca
     1981 ctgatgttaa tgagcttcag gctttgatgc ttgtttagag ctcagctccg tcttagatgg
     2041 aagggaacaa agctagggaa atggtgtctt agtgagtgct ctgttcttgg ctttacggat
     2101 gccctaactt cgtactcaca cactggcagg tgcccggtgc tctgactgag agcacgtaac
     2161 tcacctcacc cccttctgtg cagtattgaa catggaatgt aggaactaaa tactaaggac
     2221 ttagcccaga aaacctcaca ggagcaagct cgatgagggt tggtcttgaa aagctgcatt
     2281 tggatgaaag ctcagcctga gggacagcac gctgctca
//
