LOCUS       NM_001378971            4062 bp    mRNA    linear   ROD 12-FEB-2025
DEFINITION  Mus musculus histone deacetylase 7 (Hdac7), transcript variant 9,
            mRNA.
ACCESSION   NM_001378971 XM_006521203
VERSION     NM_001378971.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4062)
  AUTHORS   Ye,J., Zhong,S., Wan,H., Guo,X., Yao,X., Liu,Q., Chen,L., Wang,J.Z.
            and Xiao,S.
  TITLE     Upregulated astrocyte HDAC7 induces Alzheimer-like tau pathologies
            via deacetylating transcription factor-EB and inhibiting lysosome
            biogenesis
  JOURNAL   Mol Neurodegener 20 (1), 5 (2025)
   PUBMED   39806423
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4062)
  AUTHORS   Cheung,K.L., Zhao,L., Sharma,R., Ghosh,A.A., Appiah,M., Sun,Y.,
            Jaganathan,A., Hu,Y., LeJeune,A., Xu,F., Han,X., Wang,X., Zhang,F.,
            Ren,C., Walsh,M.J., Xiong,H., Tsankov,A. and Zhou,M.M.
  TITLE     Class IIa HDAC4 and HDAC7 cooperatively regulate gene transcription
            in Th17 cell differentiation
  JOURNAL   Proc Natl Acad Sci U S A 121 (18), e2312111121 (2024)
   PUBMED   38657041
  REMARK    GeneRIF: Class IIa HDAC4 and HDAC7 cooperatively regulate gene
            transcription in Th17 cell differentiation.
REFERENCE   3  (bases 1 to 4062)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   4  (bases 1 to 4062)
  AUTHORS   Helms,R.S., Marin-Gonzalez,A., Patel,C.H., Sun,I.H., Wen,J.,
            Leone,R.D., Duvall,B., Gao,R.D., Ha,T., Tsukamoto,T., Slusher,B.S.,
            Pomerantz,J.L. and Powell,J.D.
  TITLE     SIKs Regulate HDAC7 Stabilization and Cytokine Recall in Late-Stage
            T Cell Effector Differentiation
  JOURNAL   J Immunol 211 (12), 1767-1782 (2023)
   PUBMED   37947442
  REMARK    GeneRIF: SIKs Regulate HDAC7 Stabilization and Cytokine Recall in
            Late-Stage T Cell Effector Differentiation.
REFERENCE   5  (bases 1 to 4062)
  AUTHORS   Ling,S., Chen,T., Wang,S., Zhang,W., Zhou,R., Xia,X., Yao,Z.,
            Fan,Y., Ning,S., Liu,J., Qin,L., Tucker,H.O., Wang,N. and Guo,X.
  TITLE     Deacetylation of FOXP1 by HDAC7 potentiates self-renewal of
            mesenchymal stem cells
  JOURNAL   Stem Cell Res Ther 14 (1), 188 (2023)
   PUBMED   37507770
  REMARK    GeneRIF: Deacetylation of FOXP1 by HDAC7 potentiates self-renewal
            of mesenchymal stem cells.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4062)
  AUTHORS   Kao,H.Y., Verdel,A., Tsai,C.C., Simon,C., Juguilon,H. and
            Khochbin,S.
  TITLE     Mechanism for nucleocytoplasmic shuttling of histone deacetylase 7
  JOURNAL   J Biol Chem 276 (50), 47496-47507 (2001)
   PUBMED   11585834
REFERENCE   7  (bases 1 to 4062)
  AUTHORS   McKinsey,T.A., Zhang,C.L. and Olson,E.N.
  TITLE     Identification of a signal-responsive nuclear export sequence in
            class II histone deacetylases
  JOURNAL   Mol Cell Biol 21 (18), 6312-6321 (2001)
   PUBMED   11509672
REFERENCE   8  (bases 1 to 4062)
  AUTHORS   Dressel,U., Bailey,P.J., Wang,S.C., Downes,M., Evans,R.M. and
            Muscat,G.E.
  TITLE     A dynamic role for HDAC7 in MEF2-mediated muscle differentiation
  JOURNAL   J Biol Chem 276 (20), 17007-17013 (2001)
   PUBMED   11279209
REFERENCE   9  (bases 1 to 4062)
  AUTHORS   Downes,M., Ordentlich,P., Kao,H.Y., Alvarez,J.G. and Evans,R.M.
  TITLE     Identification of a nuclear domain with deacetylase activity
  JOURNAL   Proc Natl Acad Sci U S A 97 (19), 10330-10335 (2000)
   PUBMED   10984530
REFERENCE   10 (bases 1 to 4062)
  AUTHORS   Kao,H.Y., Downes,M., Ordentlich,P. and Evans,R.M.
  TITLE     Isolation of a novel histone deacetylase reveals that class I and
            class II deacetylases promote SMRT-mediated repression
  JOURNAL   Genes Dev 14 (1), 55-66 (2000)
   PUBMED   10640276
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC158787.14.
            
            On Mar 17, 2020 this sequence version replaced XM_006521203.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR13422600.1249956.1,
                                           SRR13422598.988947.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-137               AC158787.14        64158-64294         c
            138-328             AC158787.14        44237-44427         c
            329-419             AC158787.14        44062-44152         c
            420-531             AC158787.14        43652-43763         c
            532-647             AC158787.14        42723-42838         c
            648-773             AC158787.14        42200-42325         c
            774-865             AC158787.14        41766-41857         c
            866-976             AC158787.14        41459-41569         c
            977-1157            AC158787.14        41152-41332         c
            1158-1354           AC158787.14        40764-40960         c
            1355-1549           AC158787.14        40393-40587         c
            1550-1751           AC158787.14        39265-39466         c
            1752-1885           AC158787.14        35482-35615         c
            1886-2006           AC158787.14        35229-35349         c
            2007-2056           AC158787.14        34875-34924         c
            2057-2164           AC158787.14        33494-33601         c
            2165-2220           AC158787.14        32560-32615         c
            2221-2308           AC158787.14        32356-32443         c
            2309-2428           AC158787.14        31023-31142         c
            2429-2526           AC158787.14        30740-30837         c
            2527-2645           AC158787.14        29632-29750         c
            2646-2779           AC158787.14        28897-29030         c
            2780-2864           AC158787.14        28546-28630         c
            2865-3000           AC158787.14        26729-26864         c
            3001-4062           AC158787.14        25480-26541         c
FEATURES             Location/Qualifiers
     source          1..4062
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 53.79 cM"
     gene            1..4062
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /note="histone deacetylase 7"
                     /db_xref="GeneID:56233"
                     /db_xref="MGI:MGI:1891835"
     exon            1..137
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     CDS             119..3046
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /EC_number="3.5.1.98"
                     /note="isoform 9 is encoded by transcript variant 9;
                     histone deacetylase 7A; protein deacetylase HDAC7"
                     /codon_start=1
                     /product="histone deacetylase 7 isoform 9"
                     /protein_id="NP_001365900.1"
                     /db_xref="GeneID:56233"
                     /db_xref="MGI:MGI:1891835"
                     /translation="MHSPGAGCPALQPDTPGSQPQPMDLRVGQRPTVEPPPEPALLTL
                     QHPQRLHRHLFLAGLHQQQRSAEPMRLSMDPPMPELQGGQQEQELRQLLNKDKSKRSA
                     VASSVVKQKLAEVILKKQQAALERTVHPSSPSIPYRTLEPLDTEGAARSVLSSFLPPV
                     PSLPTEPPEHFPLRKTVSEPNLKLRYKPKKSLERRKNPLLRKESAPPSLRRRPAETLG
                     DSSPSSSSTPASGCSSPNDSEHGPNPALGSEALLGQRLRLQETSLAPFALPTVSLLPA
                     ITLGLPAPARADGDRRTHSTLGPRGPVLGNPHAPLFLHHGLEPEAGGTLPSRLQPILL
                     LDPSVSHAPLWTVPGLGPLPFHFAQPLLTTERLSGSGLHRPLNRTRSEPLPPSATASP
                     LLAPLQPRQDRLKPHVQLIKPAISPPQRPAKPSEKPRLRQIPSAEDLETDGGGVGPMA
                     NDGLEHRESGRGPPEGRGSISLQQHQQVPPWEQQHLAGRLSQGSPGDSVLIPLAQVGH
                     RPLSRTQSSPAAPVSLLSPEPTCQTQVLNSSETPATGLVYDSVMLKHQCSCGDNSKHP
                     EHAGRIQSIWSRLQERGLRSQCECLRGRKASLEELQSVHSERHVLLYGTNPLSRLKLD
                     NGKLTGLLAQRTFVMLPCGGVGVDTDTIWNELHSSNAARWAAGSVTDLAFKVASRELK
                     NGFAVVRPPGHHADHSTAMGFCFFNSVAIACRQLQQHGKASKILIVDWDVHHGNGTQQ
                     TFYQDPSVLYISLHRHDDGNFFPGSGAVDEVGTGSGEGFNVNVAWAGGLDPPMGDPEY
                     LAAFRIVVMPIAREFAPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAG
                     GAVVLALEGGHDLTAICDASEACVAALLGNKVDPLSEESWKQKPNLSAIRSLEAVVRV
                     HRKYWGCMQRLASCPDSWLPRVPGADAEVEAVTALASLSVGILAEDRPSERLVEEEEP
                     MNL"
     exon            138..328
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            329..419
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            420..531
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            532..647
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            648..773
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            774..865
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            866..976
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            977..1157
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1354
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            1355..1549
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            1550..1751
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            1752..1885
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            1886..2006
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            2007..2056
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            2057..2164
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            2165..2220
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            2221..2308
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            2309..2428
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            2429..2526
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            2527..2645
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            2646..2779
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            2780..2864
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            2865..3000
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     exon            3001..4062
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      4031
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /note="major polyA site"
     polyA_site      4062
                     /gene="Hdac7"
                     /gene_synonym="5830434K02Rik; HD7; HD7a; Hdac7a;
                     mFLJ00062"
                     /note="major polyA site"
ORIGIN      
        1 ccttcctctc gccgtctcac agtcgctctg cagcctccgg cgaccggggg gatgtgaggc
       61 cggcgccccg gccccccgcc cgccatgagc ccccggctct gagggccccg gcccctggat
      121 gcacagcccc ggcgcgggct gccctgccct ccagccagac acaccaggct ctcagcccca
      181 acccatggac ctgcgggtgg gccagcggcc cacggtggag cccccaccag agcctgcgct
      241 gctgaccctg caacaccccc aacgcctgca ccgccatctc ttcctggcag gcttacacca
      301 gcaacagcgc tcagccgagc ccatgaggct ctccatggac ccaccaatgc cggagctgca
      361 ggggggacag caggagcaag aacttcggca acttctcaat aaagacaaga gcaagcgaag
      421 tgccgtagcc agcagtgtgg tcaagcagaa gctggctgaa gtgatcctga agaaacagca
      481 ggcagccctt gagagaacag tccatcccag cagccccagt attccctaca gaactcttga
      541 gcccttggac acagagggtg ctgcccgctc cgtgcttagc agcttcctgc ctcctgttcc
      601 cagcctgccc actgaacccc cggaacactt tcccttgcgt aaaacagtgt ctgaacccaa
      661 cctgaagttg cgctacaaac ccaagaaatc cctggagaga cgcaagaatc ccctgctcag
      721 gaaggagagt gccccgccca gccttcggag gaggcctgcc gagacccttg gagattcctc
      781 ccccagtagt agcagcacac ccgcgtcagg gtgcagctcc cctaatgaca gcgagcatgg
      841 ccctaaccct gccctaggct cagaggcgct cttgggccag cggctgcggc tgcaggagac
      901 ttctctggcc ccgttcgctt tgccgacagt gtccttgctg cccgcaatca cactggggct
      961 gcctgcccct gccagggctg atggtgaccg caggacccat tcaactttag gccctcgggg
     1021 tcctgtactg gggaaccccc atgctcccct cttcctgcac cacggtctgg agccagaggc
     1081 tgggggcacc ttaccctctc gcctgcaacc cattctcctg ctggacccct cagtctctca
     1141 tgccccactg tggactgtgc ctggccttgg gcccttgccc ttccactttg cccagccctt
     1201 actgaccacc gagcggctct ctgggtcagg cctccatcga ccacttaacc ggacccgctc
     1261 agagcccctg ccccccagcg ccacagcctc ccctctgctg gcccccctgc agccccgcca
     1321 ggatcggctc aaacctcacg tccagctgat caagccagcc atctcccctc cccagaggcc
     1381 tgccaagccc agtgagaagc cccgactgcg acagataccc tcggctgagg acctagagac
     1441 agatggtggg ggagtgggac ctatggcgaa tgatggcctg gaacataggg agtcaggccg
     1501 tgggcctcct gagggcagag gctccatttc tctgcagcag catcaacagg tgccaccctg
     1561 ggagcagcag catctagccg ggcggctctc tcagggaagc cccggggact ccgtgctgat
     1621 acctctggcc caggttggac accggcccct gtccagaacc cagtcttccc cagcagcacc
     1681 tgtctccctg ctgagcccag agcccacctg tcagacccaa gtcctcaaca gctcagagac
     1741 acctgctaca gggctggtct atgactcggt gatgctgaaa caccaatgtt cctgtggaga
     1801 caacagcaag catcccgagc atgcaggccg catccagagc atctggtccc ggctgcagga
     1861 acggggtctc cgcagccagt gtgagtgtct ccgaggccga aaggcttccc tagaggagct
     1921 gcagtcagtc cactctgaac ggcacgtgct cctctacggc acgaacccac tcagccgcct
     1981 caaactggat aacgggaagc ttacaggact cctggcacag cggacgtttg tgatgctacc
     2041 ctgtggcggg gttggggtcg atactgacac catctggaac gagctgcatt cctccaatgc
     2101 agcccgctgg gctgcgggca gtgtcaccga ccttgccttc aaagtagctt cccgagagct
     2161 gaagaatggc tttgctgtgg tgcgaccccc gggacaccat gcagatcatt ctacagccat
     2221 gggcttctgc ttcttcaact ccgtggccat cgcctgccga cagctacagc aacacggcaa
     2281 agccagcaag atcctcattg ttgactggga tgttcaccat ggcaacggca cacagcagac
     2341 tttctaccag gaccccagtg tgctctacat ttcccttcat cgccatgacg acggcaactt
     2401 cttcccaggc agtggggccg tggatgaggt gggaactggc agtggcgagg gcttcaatgt
     2461 caacgtggct tgggctgggg gcttggatcc acccatgggg gatcctgagt acctggctgc
     2521 tttcaggata gtggtgatgc ccattgcccg agagtttgct ccagacctgg tcctggtgtc
     2581 tgctgggttt gatgctgcgg agggtcaccc agccccgctg ggtggctacc atgtttctgc
     2641 caaatgtttt gggtacatga cgcagcagtt gatgaacttg gcaggaggcg ccgtggtgtt
     2701 ggccttagag ggtggacatg acctcacggc catctgtgat gcctcggagg cctgtgtagc
     2761 tgctcttctg ggcaacaagg tggaccccct ttcagaagaa agctggaaac agaaacccaa
     2821 cctcagtgcc atccgctcgc tggaagctgt ggtcagggtg cacaggaaat actggggctg
     2881 catgcagcgc ttggcctcct gtccagactc ctggctaccc agagtgccgg gagctgatgc
     2941 agaagtggaa gccgtgaccg cgctggcatc cctttctgtg ggcatcctgg ctgaagacag
     3001 gccctcggag cggctggtgg aagaggaaga acccatgaac ctctagggtt tcagaacaga
     3061 tcgcgcttca aatgtggctc tcctcgtctc tgatgtcagc cctggtcctg ggtcttcaga
     3121 gatcctctgg gcaggtagtc aggtccagag cacagcctac cctgacggct atcccaagga
     3181 acttgagaag accatgggat ctgggtaggg gaccagggag gactctggga ggaagcaggt
     3241 tgggcactag ggcacagctg ggctcttcca gaacagatta ggccgtctgg tgtccacacc
     3301 cctagctgtg gtctccatcc ctccctcagg actgcacaga gggggactgg ctcaactggg
     3361 ccacccataa ccactattct taacttggcc tcggccaggg tggcctttct caggttctga
     3421 agggctagga gctggaggag ccaagggtcc cctattcctg agtacaggag agtttcctct
     3481 ctcctgtttc ctcaaatgcc tttctggtag ctctgggctc tgagagccat tctgagctgc
     3541 tctctccctg tgagtagtag tcacctgcaa gtctcccatc agtcactgtc tcgccagagg
     3601 ccaccctatg tggaccatct cagtgccccg gtgcagcaga caggtgctct ctgagtcctg
     3661 tgtctcctaa cccaacggtg ccaaaccttc atctcccttc aaaagcacaa cacaatccca
     3721 gggatgcctg gtcactgtcc ccagtatgag ccttctgttt ctggggtccc tcccacccct
     3781 cagctctggc tgctgcccca cataggacta gcttggctga ggggaacaag atgggagagt
     3841 agacagacat gggggagggg aggccacccc agaagtcttc gaggcttttg aggtttaggt
     3901 ctgggaccaa gaaagagtat ttgtgtgtat gtgtgtgtat gagtgcgtgc aagagggtat
     3961 atgtgtgtgt gtcttcccac aaccccaccg taccttgtct atgtatgcat gtttttgtaa
     4021 aaaagaaaaa agtgaaaaaa aaaaacaaac ttctgaacaa ta
//
